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公开(公告)号：US07955059B2
公开(公告)日：2011-06-07
申请号：US10598031
申请日：2005-03-02
申请人： Theodore D. Ciolkosz , Peter Kirby , Mark W. Moeller , Russell Keene , Daniel J. McCormick , Charles Murphy , Joseph A. Luongo , David R. Friswell , Theodore Dourdeville
发明人： Theodore D. Ciolkosz , Peter Kirby , Mark W. Moeller , Russell Keene , Daniel J. McCormick , Charles Murphy , Joseph A. Luongo , David R. Friswell , Theodore Dourdeville
CPC分类号： F16K15/04 , F04B53/1002 , G01N2030/326 , Y10T137/791 , Y10T137/7911 , Y10T137/7912
摘要： In various embodiments a fluid control device suitable for high pressure analytical instruments includes a housing having an interior surface with an end wall. The interior surface defines a chamber. A valve assembly disposed in the chamber controls the flow of fluid through the chamber. An end cap is disposed in the housing opposite the end wall to enclose the chamber. The end wall and end cap each have an opening to pass a fluid to the chamber or to remove a fluid from the chamber. The housing and end cap each has an abutment surface to receive the other abutment surface. At least one of the abutment surfaces has a plastic seal coating. A means of compression, such as a compression housing and compression sleeve, is included to engage the end cap to deform the plastic seal coating between the abutment surfaces and thereby seal the chamber.
摘要翻译： 在各种实施例中，适用于高压分析仪器的流体控制装置包括具有带有端壁的内表面的壳体。 内表面限定了一个室。 设置在腔室中的阀组件控制通过腔室的流体流动。 端盖设置在壳体中与端壁相对以封闭室。 端壁和端盖各自具有用于将流体传递到室的开口或从腔室去除流体。 壳体和端盖各自具有邻接表面以接收另一个邻接表面。 至少一个邻接表面具有塑料密封涂层。 包括诸如压缩壳体和压缩套筒的压缩装置以接合端盖，以使邻接表面之间的塑料密封涂层变形，从而密封腔室。
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公开(公告)号：US20080190498A1
公开(公告)日：2008-08-14
申请号：US10598072
申请日：2005-03-02
申请人： Russell Keene , David R. Friswell
发明人： Russell Keene , David R. Friswell
IPC分类号： F16K31/10 , F16K31/02 , F16K11/074
CPC分类号： F16K11/0853 , F16K5/0428 , F16K11/076 , G01N30/28 , G01N2030/207 , G01N2030/328 , Y10T137/86863 , Y10T137/86871 , Y10T137/87161
摘要： A flow through isolation valve having a stationary member; a movable member, with a surface of the stationary member interfacing with a surface of the movable member; and at least one pin isolation valve. The pin isolation valve has a flow through internal conduit and is movable so that the internal conduit can fluidically communicate with at least one blank opening in the movable member and with a flow through internal conduit in the movable member. Movement is by rotation, linear or curvilinear translation. At least one pin isolation valve is fluidically coupled typically to a sample loop of a face seal valve, or to a pump supplying high pressure liquid to or to a column discharging liquid from a face seal valve of a high pressure liquid chromatography (HPLC) system or directly to the face seal valve.
摘要翻译： 具有静止构件的通过隔离阀的流动; 可动构件，其中所述固定构件的表面与所述可动构件的表面相接合; 和至少一个针式隔离阀。 针式隔离阀具有通过内部导管的流动并且可移动，使得内部导管可与可移动构件中的至少一个坯件开口流动连通，并且流过可移动构件中的内部导管。 运动是通过旋转，线性或曲线翻译。 至少一个针式隔离阀通常流体耦合到面密封阀的样品回路，或者向从高压液相色谱（HPLC）系统的面密封阀排出液体的柱提供高压液体的泵 或直接到面密封阀。
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公开(公告)号：US20080290309A1
公开(公告)日：2008-11-27
申请号：US10597525
申请日：2005-02-18
IPC分类号： F16K1/00
CPC分类号： G01N30/20 , G01N30/22 , G01N2030/201 , G01N2030/202 , G01N2030/204 , G01N2030/207 , Y10T137/87249 , Y10T137/87692 , Y10T137/87708 , Y10T137/87788
摘要： A pin valve assembly and a method of controlling the flow of fluids comprising a pin block housing pin valves, a fluid plate with a fluid channel for fluidically communicating with the pin valves, and a fitting block housing fittings for fluidic communication with the fluid plate and for fluidic communication with fluidic components. The fluid flow through the channels of the fluid plate are controlled by the fluidic components and the pin valves.
摘要翻译： 一种针阀组件和一种控制流体流动的方法，该流体组件包括销块容纳销阀，具有用于与销阀流体连通的流体通道的流体板，以及用于与流体板流体连通的配合块壳体配件，以及 用于与流体组分的流体连通。 通过流体板的通道的流体流动由流体组件和销阀控制。
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公开(公告)号：US08931519B2
公开(公告)日：2015-01-13
申请号：US10597525
申请日：2005-02-18
CPC分类号： G01N30/20 , G01N30/22 , G01N2030/201 , G01N2030/202 , G01N2030/204 , G01N2030/207 , Y10T137/87249 , Y10T137/87692 , Y10T137/87708 , Y10T137/87788
摘要： A pin valve assembly and a method of controlling the flow of fluids comprising a pin block housing pin valves, a fluid plate with a fluid channel for fluidically communicating with the pin valves, and a fitting block housing fittings for fluidic communication with the fluid plate and for fluidic communication with fluidic components. The fluid flow through the channels of the fluid plate are controlled by the fluidic components and the pin valves.
摘要翻译： 一种针阀组件和一种控制流体流动的方法，该流体组件包括销块容纳销阀，具有用于与销阀流体连通的流体通道的流体板，以及用于与流体板流体连通的配合块壳体配件，以及 用于与流体组分的流体连通。 通过流体板的通道的流体流动由流体组件和销阀控制。
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公开(公告)号：US08539982B2
公开(公告)日：2013-09-24
申请号：US10598072
申请日：2005-03-02
申请人： Russell Keene , David R. Friswell
发明人： Russell Keene , David R. Friswell
IPC分类号： F16K11/085
CPC分类号： F16K11/0853 , F16K5/0428 , F16K11/076 , G01N30/28 , G01N2030/207 , G01N2030/328 , Y10T137/86863 , Y10T137/86871 , Y10T137/87161
摘要： A flow through isolation valve having a stationary member; a movable member, with a surface of the stationary member interfacing with a surface of the movable member; and at least one pin isolation valve. The pin isolation valve has a flow through internal conduit and is movable so that the internal conduit can fluidically communicate with at least one blank opening in the movable member and with a flow through internal conduit in the movable member. Movement is by rotation, linear or curvilinear translation. At least one pin isolation valve is fluidically coupled typically to a sample loop of a face seal valve, or to a pump supplying high pressure liquid to or to a column discharging liquid from a face seal valve of a high pressure liquid chromatography (HPLC) system or directly to the face seal valve.
摘要翻译： 具有静止构件的通过隔离阀的流动; 可动构件，其中所述固定构件的表面与所述可动构件的表面相接合; 和至少一个针式隔离阀。 销隔离阀具有通过内部导管的流动并且可移动，使得内部导管可与可移动构件中的至少一个毛坯开口流动连通，并且流过可移动构件中的内部导管。 运动是通过旋转，线性或曲线翻译。 至少一个针式隔离阀通常流体耦合到面密封阀的样品回路，或者向从高压液相色谱（HPLC）系统的面密封阀排出液体的柱提供高压液体的泵 或直接到面密封阀。
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公开(公告)号：US07735878B2
公开(公告)日：2010-06-15
申请号：US10597829
申请日：2005-03-02
申请人： Russell Keene
发明人： Russell Keene
IPC分类号： F16L25/00
CPC分类号： F16L15/009 , G01N30/6026
摘要： A coupling element (1) comprising a male sealing element (5) is disclosed herein. The male sealing element comprises a first end (7), second end (9), and a longitudinal axis extending between the first and second end. The coupling element is housed within a nut (3). In one aspect, the male sealing element has a generally cylindrical shape. Also, the male sealing element defines a fluid passageway therethrough for the transmission of fluid. The male sealing element is secured to a ferrule (13) which is located within a cavity of the nut. The first end of the male sealing element defines a conical sealing surface. In one aspect, the male conical sealing surface (17) mates with a female sealing element (23) which has a receptacle that is defined by a nearly complementary conical geometry. In this aspect, the male conical sealing surface has a mismatched angle when compared to the complementary conical female sealing element. The coupling element also has a biasing element (19) disposed between a retaining ring and the ferrule located within the nut cavity. This biasing element facilitates a fluid-tight, metal to metal (or metal to plastic, or plastic to plastic) seal between the male sealing element and female sealing element.
摘要翻译： 本文公开了包括阳密封元件（5）的联接元件（1）。 阳密封元件包括第一端（7），第二端（9）和在第一端和第二端之间延伸的纵向轴线。 联接元件容纳在螺母（3）内。 在一个方面，阳密封元件具有大致圆柱形形状。 此外，阳密封元件限定了通过其的流体通道用于流体的传输。 阳密封元件固定到位于螺母的腔内的套圈（13）。 阳密封元件的第一端限定锥形密封表面。 在一个方面，阳锥形密封表面（17）与阴密封元件（23）配合，凹密封元件（23）具有由几乎互补的圆锥形几何形状限定的容座。 在这个方面，与互补锥形阴密封元件相比，阳锥形密封表面具有不匹配的角度。 联接元件还具有设置在保持环和位于螺母腔内的套圈之间的偏置元件（19）。 该偏置元件有助于在阳密封元件和阴密封元件之间的流体密封的金属对金属（或金属对塑料或塑料到塑料）的密封。
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7.发明申请公开(公告)号：US20050194298A1
公开(公告)日：2005-09-08
申请号：US11072906
申请日：2005-03-04
IPC分类号： G01N30/22 , B01D15/08 , G01N1/14 , G01N30/04 , G01N30/06 , G01N30/16 , G01N30/20 , G01N30/24 , G01N30/26 , G01N30/32 , G01N30/86
CPC分类号： G01N1/14 , G01N2001/1427 , G01N2001/1445
摘要： The present invention is a pressurized fluid sample injector system consisting of a sample needle, multiport valve, sample loop, metering syringe and a pressure source. The method and apparatus of the present invention provides increased speed of sample transport into the sample loop by pressurizing the fluid in the system and metering the sample into the sample loop. The elevated system pressure allows the fluids to be moved faster than the vapor pressure would normally allow in a system at ambient pressure.
摘要翻译： 本发明是由样品针，多端口阀，样品环，计量注射器和压力源组成的加压流体样品注射器系统。 本发明的方法和装置通过加压系统中的流体并将样品计量到样品环中，提高了样品运送到样品回路中的速度。 升高的系统压力允许流体比在环境压力下的系统中通常允许的蒸汽压力更快地移动。
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8.发明授权公开(公告)号：US07951597B2
公开(公告)日：2011-05-31
申请号：US11532234
申请日：2006-09-15
CPC分类号： G01N1/14 , G01N2001/1427 , G01N2001/1445 , Y10T436/11 , Y10T436/119163 , Y10T436/2575
摘要： The present invention is a pressurized fluid sample injector system consisting of a sample needle, multiport valve, sample loop, metering syringe and a pressure assist pump. The speed of sample transport into the sample loop is increased by pressurizing the fluid in the system and metering the sample into the sample loop. The elevated system pressure allows the fluids to be moved faster than the vapor pressure would normally allow in a system at ambient pressure.
摘要翻译： 本发明是由采样针，多端口阀，样品回路，计量注射器和压力辅助泵组成的加压流体样品注射器系统。 通过对系统中的流体加压并将样品计量到样品回路中，样品输送到样品环中的速度增加。 升高的系统压力允许流体比在环境压力下的系统中通常允许的蒸汽压力更快地移动。
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9.发明申请Combination flow through injection and isolation valve for high pressure fluids 有权用于高压流体的注射和隔离阀的组合流公开(公告)号：US20070137713A1
公开(公告)日：2007-06-21
申请号：US10597990
申请日：2005-03-04
申请人： Russell Keene
发明人： Russell Keene
IPC分类号： F16K11/074
CPC分类号： F16K11/0856 , B01D15/14 , G01N30/20 , G01N30/22 , Y10T137/86863
摘要： A flow through injection valve having a stationary member, a movable member, a surface of the stationary member interfacing with a surface of the movable member; and at least one pin isolation valve having a flow through internal conduit and movably positioned so that the internal conduit can interface with at least one flow through conduit in the movable member. The pin isolation valves are movably positioned so that the internal conduit is also capable of fluidically communicating with another flow through internal conduit in the movable member. The flow through injection valve can be combined with a similar flow through isolation valve to serve as a multiple valve and typically for replacing a conventional face seal valve of a high pressure liquid chromatography system. The multiple valve allows flow to be transferred through without need for switching or rotating under high pressure. Movement is by rotation or translation.
摘要翻译： 具有固定构件，可动构件，与所述可动构件的表面接合的所述固定构件的表面的流过注射阀; 以及至少一个销隔离阀，其具有通过内部导管的流动并且可移动地定位，使得内部导管可与通过可移动构件中的导管的至少一个流体相接合。 销隔离阀可移动地定位，使得内部导管也能够与通过可移动构件中的内部导管的另一流体流体连通。 通过注射阀的流动可以与通过隔离阀的类似流体组合以用作多阀，并且通常用于替换高压液相色谱系统的常规面密封阀。 多个阀允许流动通过而不需要在高压下切换或旋转。 运动是通过旋转或翻译。
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公开(公告)号：US20080236243A1
公开(公告)日：2008-10-02
申请号：US10598075
申请日：2005-03-02
摘要： A device comprising a pressure monitor and a control means that receives a signal representing measured pressure at the pressure monitor and controls the controllable elements of a fluid system is utilized to monitor a fluid system for error conditions, to optimize operations and to diagnose the fluid system. By following a testing protocol that selectively enables parts of the system, the control means narrows the list of possible failing components. Comparing the measured pressure against normal pressures allows the device to identify error conditions. Determining the volume of fluid being transported and controlling the duration of the flow optimizes operation of the fluid system.
摘要翻译： 包括压力监测器和控制装置的装置用于接收表示压力监测器上测量的压力并控制流体系统的可控元件的信号，以监测流体系统的误差状况，优化操作并诊断流体系统 。 通过遵循选择性地启用系统部件的测试协议，控制装置缩小可能出现故障的部件的列表。 将测量的压力与正常压力进行比较允许设备识别错误状况。 确定正在运输的流体的体积并控制流动持续时间优化了流体系统的运行。
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