公开(公告)号：US20160047740A1

公开(公告)日：2016-02-18

申请号：US14824180

申请日：2015-08-12

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Sung Ha PARK ,  Sang Bum PARK ,  Beom Seok LEE ,  Kui Hyun KIM ,  Joo Hee PARK ,  Kyung Mi SONG ,  Euy Hyun CHO ,  Ha Na KIM

IPC: G01N21/31 ,  G01N33/49

CPC classification number: G01N21/31 ,  B01L3/5023 ,  B01L3/502715 ,  B01L3/50273 ,  B01L2200/025 ,  B01L2200/04 ,  B01L2200/148 ,  B01L2200/16 ,  B01L2300/024 ,  B01L2300/0806 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2300/161 ,  B01L2400/0409 ,  G01N21/05 ,  G01N21/274 ,  G01N21/314 ,  G01N33/492 ,  G01N2021/3129 ,  G01N2333/9108 ,  Y10T436/146666

Abstract: A sample test method, microfluidic device, and test device efficiently and accurately compensates for interference of an interfering substance present in a sample using optical measurement without addition of a separate reagent for detecting the interfering substance. The sample test method includes: measuring an optical characteristic value of a target substance present in a sample; measuring an optical characteristic value of an interfering substance present in the sample; and determining a concentration of the target substance for which interference of the interfering substance is compensated for based on the optical characteristic value of the interfering substance.

Abstract translation: 样品测试方法，微流体装置和测试装置使用光学测量有效且准确地补偿样品中存在的干扰物质的干扰，而不添加用于检测干扰物质的单独的试剂。 样品测试方法包括：测量样品中存在的目标物质的光学特性值; 测量样品中存在的干扰物质的光学特性值; 并根据干扰物质的光学特性，确定补偿了干扰物质的干扰的目标物质的浓度。

公开(公告)号：US20180180536A1

公开(公告)日：2018-06-28

申请号：US15891632

申请日：2018-02-08

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Sung Ha PARK ,  Sang Bum PARK ,  Beom Seok LEE ,  Kui Hyun KIM ,  Joo Hee PARK ,  Kyung Mi SONG ,  Euy Hyun CHO ,  Ha Na KIM

IPC: G01N21/31 ,  G01N21/05 ,  G01N21/27 ,  G01N33/49

CPC classification number: G01N21/31 ,  B01L3/5023 ,  B01L3/502715 ,  B01L3/50273 ,  B01L2200/025 ,  B01L2200/04 ,  B01L2200/148 ,  B01L2200/16 ,  B01L2300/024 ,  B01L2300/0806 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2300/161 ,  B01L2400/0409 ,  G01N21/05 ,  G01N21/274 ,  G01N21/314 ,  G01N33/492 ,  G01N2021/3129 ,  G01N2333/9108 ,  Y10T436/146666

Abstract: A sample test method, microfluidic device, and test device efficiently and accurately compensates for interference of an interfering substance present in a sample using optical measurement without addition of a separate reagent for detecting the interfering substance. The sample test method includes: measuring an optical characteristic value of a target substance present in a sample; measuring an optical characteristic value of an interfering substance present in the sample; and determining a concentration of the target substance for which interference of the interfering substance is compensated for based on the optical characteristic value of the interfering substance.

公开(公告)号：US20150147769A1

公开(公告)日：2015-05-28

申请号：US14528157

申请日：2014-10-30

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Kui Hyun KIM ,  Taguchi TAKAYUKI ,  Sung Joon PARK ,  Chang Soo PARK ,  Sang Hyun BAEK ,  Tae Han LEE

IPC: C12Q1/40 ,  G01N21/78

CPC classification number: C12Q1/40 ,  G01N21/78 ,  Y10T436/19

Abstract: A method of testing a sample to determine a concentration of a target material included in the sample and a microfluidic device in which a reaction of the sample and a reagent occurs are provided. The method includes mixing a sample with a reagent that changes optical characteristics in accordance with a concentration of chlorine ions in the sample, and a capturing material that captures some of the chlorine ions in the sample; measuring the optical characteristics after mixing the sample with the reagent and the capturing material; and determining a concentration of the chlorine ions in the sample based on the measured optical characteristics.

Abstract translation: 提供了测试样品以确定样品中包含的靶材料的浓度的方法和其中发生样品和试剂的反应的微流体装置。 该方法包括将样品与根据样品中氯离子的浓度改变光学特性的试剂和捕获样品中的一些氯离子的捕获材料混合; 测量样品与试剂和捕获材料混合后的光学特性; 并根据所测量的光学特性确定样品中氯离子的浓度。

公开(公告)号：US20150168361A1

公开(公告)日：2015-06-18

申请号：US14567541

申请日：2014-12-11

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Takashi SHIMAYAMA ,  Kui Hyun KIM ,  Ji Yun KANG ,  Soo Hong KIM ,  Sung Joon PARK

IPC: G01N31/22 ,  G01N27/00 ,  G01N21/00

CPC classification number: G01N31/22 ,  C12Q1/00 ,  G01N21/00 ,  G01N27/00 ,  G01N33/573 ,  G01N33/84

Abstract: An assay method enhances reliability of assay of a target material by removing interfering influence of non-target materials through controlling the concentration of the target material in a sample. A reagent kit, a microfluidic device, and a test apparatus are disclosed. The method includes capturing a target material using a capturing agent which selectively binds the target material and determining measured values of reaction products of an enzyme which is activated by the target material, wherein enzyme reactions are conducted in the presence and absence of the capturing agent.

Abstract translation: 测定方法通过通过控制样品中目标材料的浓度来消除非目标材料的干扰影响来提高目标材料的测定的可靠性。 公开了一种试剂盒，微流体装置和测试装置。 该方法包括使用选择性结合目标材料并确定被靶材料活化的酶的反应产物的测量值的捕获剂捕获目标物质，其中在存在和不存在捕获剂的情况下进行酶反应。

公开(公告)号：US20130115135A1

公开(公告)日：2013-05-09

申请号：US13730554

申请日：2012-12-28

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Beom Seok LEE ,  Ji Won KIM ,  Jeong Gun LEE ,  Kui Hyun KIM

IPC: B01L3/00

CPC classification number: B01L3/50273 ,  B01L3/502738 ,  B01L3/545 ,  B01L2200/0621 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2300/021 ,  B01L2300/0806 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/161 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0677 ,  G01N21/07 ,  G01N33/54386 ,  G01N35/00069

Abstract: Provided is a microfluidic apparatus including: a microfluidic structure for providing spaces for receiving a fluid and for forming channels, through which the fluid flows; and valves for controlling the flow of fluid through the channels in the microfluidic apparatus. The microfluidic structure includes: a sample chamber; a sample separation unit receiving the sample from the sample chamber and separating a supernatant from the sample by using a centrifugal force; a testing unit receiving the supernatant from the sample separation unit for detecting a specimen from the supernatant using an antigen-antibody reaction, and a quality control chamber for identifying reliability of the test.

Abstract translation: 提供了一种微流体装置，包括：微流体结构，用于提供用于接收流体的空间和用于形成流体流过的通道; 以及用于控制通过微流体装置中的通道的流体流动的阀。 微流体结构包括：样品室; 样品分离单元，从样品室接收样品，并通过离心力从样品中分离上清液; 接收来自样品分离单元的上清液的测试单元，用于使用抗原 - 抗体反应从上清液检测样品;以及质量控制室，用于识别测试的可靠性。