公开(公告)号：US07209775B2

公开(公告)日：2007-04-24

申请号：US10824387

申请日：2004-04-15

申请人： Sang-kon Bae ,  Gil-won Yoon ,  Jong-youn Lee

发明人： Sang-kon Bae ,  Gil-won Yoon ,  Jong-youn Lee

IPC分类号： A61B5/00 ,  A61B5/02 ,  A61B5/08

CPC分类号： G01J5/04 ,  A61B5/0002 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/02438 ,  A61B5/0816 ,  A61B5/14552 ,  A61B5/6817 ,  G01J5/02 ,  G01J5/025 ,  G01J5/049 ,  G01J5/08 ,  G01J5/0846 ,  H04R1/1016 ,  H04R2420/07

摘要： An apparatus for measuring a bio signal including a bio signal measurement unit, which is insertable into an ear to be in close contact with an internal surface of the ear, the bio signal measurement unit having a photo plethysmography (PPG) measurement module for radiating light of different wavelengths onto the internal surface of the ear, detecting light transmitted through the ear, and outputting a PPG signal including bio information, a control unit having a PPG signal processor for generating the bio information using the PPG signal measured by the PPG measurement module, and an output unit for displaying the bio information generated from the control unit.

摘要翻译： 一种用于测量生物信号的装置，包括生物信号测量单元，该生物信号测量单元可插入耳朵以与耳朵的内表面紧密接触，所述生物信号测量单元具有用于照射光的照相体积描记术（PPG）测量模块 在耳内表面上检测透过耳朵的光，并输出包含生物信息的PPG信号，具有PPG信号处理器的控制单元，用于使用由PPG测量模块测量的PPG信号产生生物信息 以及用于显示从控制单元生成的生物信息的输出单元。

公开(公告)号：US07169110B2

公开(公告)日：2007-01-30

申请号：US10830113

申请日：2004-04-23

申请人： Jong-youn Lee ,  Gil-won Yoon

发明人： Jong-youn Lee ,  Gil-won Yoon

IPC分类号： A61B5/08

CPC分类号： A61B5/14551 ,  A61B5/4818 ,  A61B2503/06

摘要： An apparatus for diagnosing sleep apnea, which detects a temporary cessation of breathing during sleep by applying light to a part of a subject's body and processing light output therefrom, includes a light source unit for sequentially generating light of at least two different wavelengths according to a control signal, a photodetecting unit for detecting the light, which are generated by the light source unit and applied to the body part, and for converting the detected light signals into electric signals, a diagnosis unit for substantially removing a time delay between the electric signals output from the photodetecting unit, for calculating a ratio between the electric signals, and for comparing the ratio with a predetermined reference value to diagnose sleep apnea, and a controller for outputting the control signal to the light source unit to generate the light signals, and for providing the predetermined reference value to the diagnosis unit.

摘要翻译： 一种用于诊断睡眠呼吸暂停的装置，其通过将光照射到被检体的一部分并且处理从其输出的光来检测睡眠期间的呼吸暂时停止，该装置包括：光源单元，其用于依次产生至少两个不同波长的光， 控制信号，用于检测由光源单元产生并施加到身体部分的光的光检测单元，以及用于将检测到的光信号转换为电信号;诊断单元，用于基本上消除电信号之间的时间延迟 从所述光检测单元输出，用于计算所述电信号之间的比例，以及将所述比率与预定参考值进行比较以诊断睡眠呼吸暂停;以及控制器，用于将所述控制信号输出到所述光源单元以产生所述光信号，以及 用于向诊断单元提供预定的参考值。

公开(公告)号：US06719702B2

公开(公告)日：2004-04-13

申请号：US10155136

申请日：2002-05-28

申请人： Jong-youn Lee ,  Gil-won Yoon

发明人： Jong-youn Lee ,  Gil-won Yoon

IPC分类号： A61B502

CPC分类号： A61B5/02225 ,  A61B5/021

摘要： An apparatus and method for measuring blood pressure using linearly varying air pressure, including a compression unit; an air pump that injects air into the compression unit; a pressure sensor that senses and outputs the air pressure of the compression unit; an ADC that converts and outputs the result of the sensing as a pressure signal; a controller that calculates a current pressure value of the compression unit from the pressure signal and a linear pressure of the compression unit that is linearly dropped corresponding to the current pressure value and generates the first control signal in response to the current pressure value and a second control signal from the result of a comparison of the current pressure value and the linear pressure; a DAC that converts and outputs the second control signal as an exhaust control signal; and a proportional control valve that exhausts air from the compression unit.

摘要翻译： 一种使用线性变化的空气压力测量血压的装置和方法，包括压缩单元; 空气泵，其将空气注入压缩单元; 感测并输出压缩单元的空气压力的压力传感器; 将感测结果转换并输出作为压力信号的ADC; 控制器，根据压力信号计算压缩单元的当前压力值，以及根据当前压力值线性下降的压缩单元的线性压力，并响应于当前压力值产生第一控制信号，第二 根据当前压力值与线性压力的比较结果的控制信号; DAC，其作为排气控制信号转换并输出第二控制信号; 以及从压缩单元排出空气的比例控制阀。

公开(公告)号：US08507281B2

公开(公告)日：2013-08-13

申请号：US10753218

申请日：2004-01-07

申请人： Jong-youn Lee ,  Gil-won Yoon

发明人： Jong-youn Lee ,  Gil-won Yoon

IPC分类号： G01N33/49

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  G06F19/00 ,  Y10T436/102499 ,  Y10T436/105831 ,  Y10T436/106664

摘要： A method of removing abnormal data in a blood component analysis system using spectroscopy to estimate a concentration of a blood component by analyzing a photo-plethysmographic (PPG) signal obtained by radiating light of first and second wavelengths reacting to the blood component on a subject and detecting light corresponding to the first and second wavelengths output from the subject, includes collecting the PPG signal corresponding to the first and second wavelengths for a predetermined unit period of time, calculating “n” parameters, with respect to “n” pulse data included in the collected PPG signal, where n is a positive integer, calculating an average of the “n” parameters, and comparing a ratio of a number of parameters whose deviation from the average is greater than a predetermined standard deviation to the “n” parameters with a predetermined removal reference value to determine whether the “n” pulse data is valid.

摘要翻译： 一种使用光谱法去除血液成分分析系统中的异常数据的方法，通过分析通过辐射对受试者对血液成分起反应的第一和第二波长的光而获得的光体积描记（PPG）信号来估计血液成分的浓度， 检测对应于从被摄体输出的第一和第二波长的光，包括在预定的单位时间段内收集对应于第一和第二波长的PPG信号，相对于包括在“ 收集的PPG信号，其中n是正整数，计算“n”个参数的平均值，并且将与平均值的偏差大于预定标准偏差的参数数的比率与“n”个参数进行比较， 预定的去除参考值以确定“n”个脉冲数据是否有效。

公开(公告)号：US06990426B2

公开(公告)日：2006-01-24

申请号：US10387552

申请日：2003-03-14

申请人： Gil-won Yoon ,  Hong-sig Kim ,  Kye-jin Jeon ,  Jong-youn Lee ,  Kun-kook Park ,  Su-jin Kim ,  Hoon-jong Jwa

发明人： Gil-won Yoon ,  Hong-sig Kim ,  Kye-jin Jeon ,  Jong-youn Lee ,  Kun-kook Park ,  Su-jin Kim ,  Hoon-jong Jwa

IPC分类号： A61B5/02

CPC分类号： A61B5/02007 ,  A61B5/02416 ,  A61B5/0816 ,  A61B5/14551 ,  A61B5/7239 ,  G01N21/31

摘要： A diagnosis method and apparatus for measuring blood hemoglobin concentration, oxygen saturation, pulse rate, respiration rate, or degree of aging of blood vessels using light includes an input/output unit for receiving a command for measurement from a user and for providing information on the result of a measurement to the user; a control unit for receiving the command for measurement from the input/output unit and for generating a control signal; a light generating unit for generating at least two light beams for measurement according to the control signal; a light receiving unit for receiving the light beams transmitted through an object that is subject to measurement and for converting the received light beams into electrical signals; and a data processing unit for processing the electrical signals received from the light receiving unit and for outputting information on the result of a predetermined measurement.

公开(公告)号：US6026314A

公开(公告)日：2000-02-15

申请号：US149219

申请日：1998-09-08

申请人： Airat K. Amerov ,  Kye-jin Jeon ,  Yoen-joo Kim ,  Gil-won Yoon

发明人： Airat K. Amerov ,  Kye-jin Jeon ,  Yoen-joo Kim ,  Gil-won Yoon

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1455

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  A61B5/14546

摘要： A method and device for noninvasive measurement of blood component concentrations utilizes pulsed polychromatic light source emitting, light in the near infrared range 800-1850 nm. The light is back scattered from or transmitted through a part of a patient's body. Back scattered light from blood-containing tissues and blood vessels has information on blood component concentrations. That light is collected to avoid the surface reflection from the skin surface and to minimize the effects of changes in the scattering background. The concentrations of blood components are calculated from the spectral analysis based on selected wavelengths by a defined algorithm. A microprocessor calculates and determines the blood component concentrations by comparing a ratio with a calibration curve stored in a memory of the microprocessor. The calculated concentration values are displayed on a display.

摘要翻译： 用于非侵入性测量血液成分浓度的方法和装置利用发射近红外范围800-1850nm的光的脉冲多色光源。 光从背部散开或通过患者身体的一部分传播。 来自血液的组织和血管的背散射光具有关于血液成分浓度的信息。 收集该光以避免来自皮肤表面的表面反射并使散射背景中的变化的影响最小化。 血液成分的浓度由基于所选择的波长的光谱分析通过定义的算法计算。 微处理器通过将比率与存储在微处理器的存储器中的校准曲线进行比较来计算和确定血液成分浓度。 计算出的浓度值显示在显示屏上。

公开(公告)号：US06921366B2

公开(公告)日：2005-07-26

申请号：US10390614

申请日：2003-03-19

申请人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang

发明人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang

IPC分类号： G01N29/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B8/00 ,  G01N21/00 ,  G01N21/17 ,  G01N21/49

CPC分类号： A61B5/1455 ,  A61B5/0059 ,  A61B5/0095 ,  A61B5/14532 ,  G01N21/1702 ,  G01N21/49 ,  G01N2021/1706

摘要： An apparatus and method for non-invasively measuring bio-fluid concentrations using photoacoustic spectroscopy includes a light source for irradiating an incident light having a predetermined wavelength band to be absorbed into a targeted component of a living body, an acoustic signal generator for generating a first acoustic signal having a similar frequency band as a photoacoustic signal that is generated when the incident light is absorbed into the targeted component, a ultrasonic translator for detecting the photoacoustic signal and a second acoustic signal that is a modulated signal of the first acoustic signal, a controller for generating the first acoustic signal in a predetermined frequency band, a light detector for detecting an intensity of the incident light, and a calculator capable of calculating a signal compensation value based on the incident light, the photoacoustic signal, and the coefficient of sound wave transmission, and capable of computing a concentration of the targeted component.

摘要翻译： 使用光声波光谱法非侵入性地测量生物流体浓度的装置和方法包括用于将具有预定波长带的入射光照射以吸收到生物体的目标组分中的光源;声信号发生器，用于产生第一 声光信号具有与入射光被吸收到目标成分中时产生的光声信号相似的频带，用于检测光声信号的超声波转换器和作为第一声信号的调制信号的第二声信号， 用于产生预定频带中的第一声信号的控制器，用于检测入射光强度的光检测器和能够基于入射光，光声信号和声系数计算信号补偿值的计算器 波传输，并能计算浓度 目标组件。

公开(公告)号：US07572229B2

公开(公告)日：2009-08-11

申请号：US10632963

申请日：2003-08-04

申请人： Hyung-sok Yeo ,  Hong-sig Kim ,  Gil-won Yoon

发明人： Hyung-sok Yeo ,  Hong-sig Kim ,  Gil-won Yoon

IPC分类号： A61B5/00

CPC分类号： A61B5/6826 ,  A61B5/02241 ,  A61B5/14552 ,  A61B5/6838 ,  A61B5/6843

摘要： A probe for use in photoplethysmographic (PPG) measurement includes a light source unit including a light source that contacts a predetermined site of an object and emits light onto the predetermined site, a photodetector unit positioned facing the light source unit to receive the light emitted from the light source unit and transmitted through the object, a body having a space for receiving the object and in which the light source unit and the photodetector unit are positioned in a same optical axis, and a pressure application unit coupled to the body for applying a pressure to the object via the light source unit. A biological signal measuring system includes the above probe, a controller for controlling operations of the probe and for recording and analyzing signals output from the probe, a detected light intensity display unit for displaying an intensity of detected light, and a biological signal display unit.

摘要翻译： 用于光电容积测量（PPG）测量的探针包括光源单元，其包括接触物体的预定位置并将光发射到预定位置的光源;光检测器单元，定位成面对光源单元，以接收从 所述光源单元并且透过所述物体，具有用于接收所述物体的空间并且所述光源单元和所述光电检测器单元位于同一光轴上的主体，以及耦合到所述主体的施加压力的压力施加单元， 通过光源单元对物体的压力。 生物信号测量系统包括上述探针，控制器，用于控制探头的操作，以及用于记录和分析从探头输出的信号，检测的光强度显示单元，用于显示检测到的光的强度;以及生物信号显示单元。

公开(公告)号：US07107087B2

公开(公告)日：2006-09-12

申请号：US10801612

申请日：2004-03-17

申请人： In-duk Hwang ,  Gil-won Yoon ,  Sang-joon Han ,  Kye-jin Jeon

发明人： In-duk Hwang ,  Gil-won Yoon ,  Sang-joon Han ,  Kye-jin Jeon

IPC分类号： A61B5/00 ,  G01J3/42

CPC分类号： A61B5/1455 ,  A61B5/14532 ,  G01J3/1256 ,  G01N21/31

摘要： A method of measuring a concentration of a component in a subject includes setting an intensity relationship equation between a positive-order beam and a negative-order beam with respect to a reference matter at a particular wavelength, applying a light having a first wavelength band absorbed by the component and detecting an intensity of a positive-order beam output from the subject and an intensity of a negative-order beam output from the reference matter, the positive-order beam and the negative-order beam having a second wavelength band, calculating an intensity of a positive-order beam input to the subject by applying the intensity of the negative-order beam output from the reference matter to the intensity relationship equation, and calculating absorbance using the intensity of the positive-order beam output from the subject and the intensity of the positive-order beam input to the subject and measuring a concentration of the component using the absorbance.

摘要翻译： 测定被检体内成分浓度的方法包括：在特定波长下设定正序光束与负光束之间的强度关系方程式，将具有吸收的第一波长带的光 通过分量并检测从对象输出的正阶光束的强度和从参考物质输出的负光束的强度，正阶光束和负光束具有第二波长带，计算 通过将从参考物质输出的负光束的强度施加到强度关系式来输入到对象的正阶光束的强度，并且使用从被摄体输出的正阶光束的强度来计算吸光度，以及 输入到对象的正阶光束的强度，并使用吸光度测量成分的浓度。

公开(公告)号：US07248911B2

公开(公告)日：2007-07-24

申请号：US10802920

申请日：2004-03-18

申请人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang ,  Sang-joon Han

发明人： Kye-jin Jeon ,  Gil-won Yoon ,  In-duk Hwang ,  Sang-joon Han

IPC分类号： A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/0053 ,  A61B5/107 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B2560/0223 ,  G01N21/359 ,  G01N2021/036 ,  G01N2021/3144 ,  G01N2201/0662

摘要： In an apparatus and method of noninvasively measuring a concentration of a blood component, the method includes (a) varying a thickness of a body part of a subject, measuring absorption spectrums at different thicknesses of the body part, obtaining a first differential absorption spectrum between the absorption spectrums measured at different thicknesses, actually measuring concentrations of the blood component, and establishing a statistical model using the first differential absorption spectrum and the actually measured concentrations; and (b) estimating the concentration of the blood component using a second differential absorption spectrum obtained with respect to the body part based on the statistical model.

摘要翻译： 在非侵入性地测量血液成分浓度的装置和方法中，该方法包括：（a）改变被检体的身体部位的厚度，测量身体部位的不同厚度的吸收光谱，获得第一差异吸收光谱， 在不同厚度下测量的吸收光谱，实际测量血液成分的浓度，并使用第一个差示吸收光谱和实际测量的浓度建立统计模型; 和（b）基于统计模型使用相对于身体部位获得的第二差分吸收光谱估计血液成分的浓度。