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公开(公告)号：US20060084930A1
公开(公告)日：2006-04-20
申请号：US11252176
申请日：2005-10-17
申请人： Sridevi Dhanaraj , Dhanuraj Shetty , Hiep Do , Sanyog Pendharkar
发明人： Sridevi Dhanaraj , Dhanuraj Shetty , Hiep Do , Sanyog Pendharkar
IPC分类号： A61F13/00
CPC分类号： A61L31/042 , A61F2/0063 , A61F13/00 , A61F2013/00604 , A61F2013/00927 , A61L15/26 , A61L15/28 , A61L27/18 , A61L27/20 , A61L27/48 , A61L27/58 , A61L31/06 , A61L2430/06 , A61L2430/10 , A61L2430/24 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/06 , B32B5/10 , B32B5/26 , B32B9/04 , B32B2250/02 , B32B2250/20 , B32B2262/0276 , B32B2262/04 , B32B2262/06 , B32B2307/726 , B32B2459/00 , B32B2535/00 , D04H1/435 , D04H1/4374 , Y10T442/3707 , Y10T442/494 , C08L67/04 , C08L1/00 , C08L1/24 , C08L1/04
摘要： The present invention is directed to a method of using a multilayered fabric comprising a first absorbable nonwoven fabric and a second absorbable woven or knitted fabric in tissue repair and regeneration.
摘要翻译： 本发明涉及一种在组织修复和再生中使用包含第一可吸收性无纺布和第二可吸收编织物或针织物的多层织物的方法。
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公开(公告)号：US08221780B2
公开(公告)日：2012-07-17
申请号：US11427477
申请日：2006-06-29
IPC分类号： A61F2/00
CPC分类号： A61L27/56 , A61F2/30756 , A61F2/3872 , A61F2002/30766 , A61L27/18 , A61L27/54 , A61L27/58 , A61L2300/252 , A61L2300/414 , A61L2430/06 , C08L67/04
摘要： A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.
摘要翻译： 公开了一种生物相容性半月板修复装置。 所述组织修复装置包括适于与弯液面中的缺陷接触的支架，所述支架包括高密度干法铺设的非织造聚合物材料和生物相容性泡沫。 支架提供增加的缝线拉拔强度。
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公开(公告)号：US20090246247A1
公开(公告)日：2009-10-01
申请号：US12411428
申请日：2009-03-26
CPC分类号： A61K35/38 , A61F2/042 , A61K35/22 , A61L27/18 , A61L27/3604 , A61L27/3629 , A61L27/3679 , A61L27/56 , A61L2430/22 , C08L67/04
摘要： The present invention relates to methods for tissue augmentation or regeneration. More specifically, the present invention provides for a composite enterocystoplasty procedure using a biocompatible scaffold and minced autologous tissue for implantation in a mammalian bladder.
摘要翻译： 本发明涉及组织增生或再生的方法。 更具体地，本发明提供了使用生物相容性支架和切割的自体组织用于植入哺乳动物膀胱中的复合肠内成形术程序。
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公开(公告)号：US08110210B2
公开(公告)日：2012-02-07
申请号：US10828838
申请日：2004-04-20
IPC分类号： A61F2/00
摘要： A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.
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公开(公告)号：US20080268016A1
公开(公告)日：2008-10-30
申请号：US12107290
申请日：2008-04-22
CPC分类号： A61K35/22 , A61L27/3604 , A61L27/3629 , A61L27/3641 , A61L27/3804 , A61L27/48 , A61L2430/26
摘要： Biocompatible tissue repair implant devices and their methods of use are provided for repairing a diseased kidney tissue. The present invention relates to methods of removing a portion of kidney tissue from a host or donor, mincing it, placing it on a bioresorbable scaffold, and implanting the scaffold into a defect site in a kidney of a host or patient for use in the treatment of degenerative kidney diseases. The compositions and methods provide a pluripotent milieu for the de-novo generation of renal tubular structures in the replacement of diseased kidney tissue. The processes and devices are useful in the treatment of medical conditions and diseases relating to the kidneys such as trauma, necrosis, and both acute and chronic forms of renal failure.
摘要翻译： 生物相容性组织修复植入装置及其使用方法被提供用于修复患病的肾组织。 本发明涉及从宿主或供体去除一部分肾组织的方法，将其切碎，将其置于生物可再吸收的支架上，以及将支架植入宿主或患者的肾脏中的缺陷部位用于治疗 的退行性肾脏疾病。 组合物和方法提供用于替代患病肾组织的肾小管结构的新生代的多功能环境。 方法和装置可用于治疗与肾脏相关的医学病症和疾病，例如创伤，坏死，以及急性和慢性肾衰竭形式。
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公开(公告)号：US20050232967A1
公开(公告)日：2005-10-20
申请号：US10828838
申请日：2004-04-20
CPC分类号： A61L27/56 , A61F2/3872 , A61L27/18 , A61L2430/06 , C08L67/04
摘要： A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.
摘要翻译： 公开了一种生物相容性半月板修复装置。 所述组织修复装置包括适于与弯液面中的缺陷接触的支架，所述支架包括高密度干法铺设的非织造聚合物材料和生物相容性泡沫。 支架提供增加的缝线拉拔强度。
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公开(公告)号：US08105621B2
公开(公告)日：2012-01-31
申请号：US11427477
申请日：2006-06-29
IPC分类号： A61F2/00
摘要： A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.
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公开(公告)号：US20090263484A1
公开(公告)日：2009-10-22
申请号：US12107408
申请日：2008-04-22
申请人： Joseph J. Hammer , Dhanuraj Shetty , Sridevi Dhanaraj , Ziwei Wang , Jeffrey C. Geesin , Daniel J. Keeley
发明人： Joseph J. Hammer , Dhanuraj Shetty , Sridevi Dhanaraj , Ziwei Wang , Jeffrey C. Geesin , Daniel J. Keeley
CPC分类号： A61K35/34 , A61K35/22 , A61K38/00 , A61L27/3604 , A61L27/3834 , A61K2300/00
摘要： Tissue engineering devices and methods are provided for the reconstruction, repair, augmentation, or replacement of a luminal organ or tissue structure involving the use of a biodegradable polymer matrix conforming to a portion of a laminarly arranged luminal organ, the processing of autologous, allogeneic or xenogeneic tissue comprising multiple cell populations to obtain a minced tissue composition, the seeding of the matrix with the composition, and the implanting of the seeded polymer matrix into a patient.
摘要翻译： 提供组织工程装置和方法用于重建，修复，增加或更换腔内器官或组织结构，其涉及使用符合层状布置的器官器官的一部分的生物可降解聚合物基质，自体，异基因或 包含多个细胞群体的异种组织以获得切碎的组织组合物，用组合物接种基质，以及将接种的聚合物基质植入患者体内。
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公开(公告)号：US08137686B2
公开(公告)日：2012-03-20
申请号：US10828838
申请日：2004-04-20
IPC分类号： A61F2/00
CPC分类号： A61L27/56 , A61F2/3872 , A61L27/18 , A61L2430/06 , C08L67/04
摘要： A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.
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公开(公告)号：US20090148495A1
公开(公告)日：2009-06-11
申请号：US11954100
申请日：2007-12-11
CPC分类号： A61F2/30756 , A61F2/30907 , A61F2002/30062 , A61F2002/30766 , A61F2210/0004 , A61F2310/00329 , A61L27/18 , A61L27/38 , A61L27/56 , C08L67/04
摘要： An implantable biodegradable porous fibrous matrix is disclosed, the fibrous matrix being constructed of fibers arranged in a nonwoven array. The density of the nonwoven array is adjusted in the manufacturing process to obtain an optimum density of the array for tissue ingrowth. When implanted, the optimum density fibrous matrix provides for a superior biological response of the host in terms of tissue growth, especially for tissues containing glycosaminoglycans (GAGs). The optimum density fibrous matrix is therefore provided with properties useful in repair and/or regeneration of mammalian tissue.
摘要翻译： 公开了可植入的可生物降解的多孔纤维基质，所述纤维基质由布置成无纺布阵列的纤维构成。 在制造过程中调节非织造布阵列的密度以获得用于组织向内生长的阵列的最佳密度。 当植入时，最佳密度纤维基质在组织生长方面提供了优异的宿主生物反应，特别是对于含有糖胺聚糖（GAG）的组织。 因此，最佳密度纤维基质具有可用于哺乳动物组织的修复和/或再生的性质。
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