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公开(公告)号：US5468847A
公开(公告)日：1995-11-21
申请号：US209700
申请日：1994-03-10
申请人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson , Jerald K. Rassmussen , Michael G. Williams
发明人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson , Jerald K. Rassmussen , Michael G. Williams
IPC分类号： G01N33/48 , A61K38/00 , A61K47/48 , B01D15/08 , B01D39/08 , B01D39/16 , C07K1/22 , C07K1/34 , C07K17/14 , C08B37/00 , C12P21/00 , G01N1/10 , C07K1/16 , B01D61/08 , C07K1/18
CPC分类号： B01D39/083 , B01D15/08 , B01D39/086 , B01D39/1623 , B01D39/18 , B01D39/2068 , C07K1/34 , B01D15/361 , B01D15/3804 , B01D2239/0407 , B01D2239/0428 , B01D2239/1291
摘要： The invention provides a method of separating a biomacromolecule which comprises the steps of providing a separation system including a filter element which comprises a composite filtration medium, the composite filtration medium comprising a filtration layer on the upstream surface of which are located insoluble stationary phase particulates, the particulates being capable of binding to a biomacromolecule or class of biomacromolecules, a reservoir containing a solution mixture comprising at least one biomacromolecule as solute, and a pump and associated tubing to form a closed loop assembly, and recirculation pumping the solution mixture through the filter cartridge so as to bind the at least one biomacromolecule to the stationary phase particulate so as to form a biomacromolecule:stationary phase particulate product. An eluting solution can be pumped through the closed loop assembly which is capable of reversing the biomacromolecule:stationary phase particulate product binding interaction so as to liberate the biomacromolecule.
摘要翻译： 本发明提供了分离生物大分子的方法，其包括提供包括复合过滤介质的过滤元件的分离系统的步骤，所述复合过滤介质在其上游表面上设置有不溶性固定相颗粒的过滤层， 能够结合生物大分子或一类生物大分子的颗粒，含有至少一种作为溶质的生物大分子的溶液混合物的储存器，以及泵和相关管道以形成闭环组件，以及再循环泵送溶液混合物通过过滤器 以便将至少一种生物大分子结合至固定相颗粒，以便形成生物大分子：固定相颗粒产物。 洗脱溶液可以泵送通过闭环组件，其能够逆转生物大分子：固定相颗粒产物结合相互作用以释放生物大分子。
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公开(公告)号：US5614105A
公开(公告)日：1997-03-25
申请号：US425585
申请日：1995-04-20
申请人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson
发明人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson
摘要： Insolubilized enzyme particulates are located on the upstream surface of a filtration layer of a filtering element which can be used in a cartridge filter. Employed in a recycling flow reaction system at relatively high flux rates, the cartridges are useful for conducting catalyzed chemical reactions of dissolved solutes, for example, esterifications, isomerizations, oxidations, reductions, and cyclizations.
摘要翻译： 不溶解的酶微粒位于可用于筒式过滤器的过滤元件的过滤层的上游表面上。 在相对较高的通量速率下在回收流动反应系统中使用，所述筒可用于进行溶解的溶质的催化化学反应，例如酯化，异构化，氧化，还原和环化。
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公开(公告)号：US5478466A
公开(公告)日：1995-12-26
申请号：US427281
申请日：1995-04-21
申请人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson
发明人： Steven M. Heilmann , Gary J. Drtina , Philip D. Eitzman , Louis C. Haddad , Frederick W. Hyde , Todd W. Johnson
IPC分类号： B01D39/14 , C12M1/40 , C12N11/00 , C12N11/02 , C12N11/04 , C12N11/08 , B01D36/00 , B01D27/00
摘要： Insolubilized enzyme particulates are located on the upstream surface of a filtration layer of a filtering element which can be used in a cartridge filter. Employed in a recycling flow reaction system at relatively high flux rates, the cartridges are useful for conducting catalyzed chemical reactions of dissolved solutes, for example, esterifications, isomerizations, oxidations, reductions, and cyclizations.
摘要翻译： 不溶解的酶微粒位于可用于筒式过滤器的过滤元件的过滤层的上游表面上。 在相对较高的通量速率下在回收流动反应系统中使用，所述筒可用于进行溶解的溶质的催化化学反应，例如酯化，异构化，氧化，还原和环化。
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公开(公告)号：US5679779A
公开(公告)日：1997-10-21
申请号：US447852
申请日：1995-05-23
申请人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
发明人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
IPC分类号： B01J31/06 , A61K47/32 , C08F20/36 , C08F212/36 , C08F220/20 , C08F220/34 , C08F220/36 , C08F220/56 , C08G18/64 , C08G18/72 , C12N11/08 , C08K17/02
CPC分类号： C08G18/728 , C08F20/36 , C08F220/36 , C08G18/6446 , C12N11/08 , Y10S530/815
摘要： Insoluble supports are prepared which possess high surface areas and efficiently dispersed isocyanate groups. These reactive supports are useful for covalently binding proteins which preferably are enzymes and provide catalysts for conducting organic reactions.
摘要翻译： 制备具有高表面积和有效分散的异氰酸酯基团的不溶性载体。 这些反应性支持物可用于共价结合蛋白质，其优选为酶并提供用于进行有机反应的催化剂。
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公开(公告)号：US6018009A
公开(公告)日：2000-01-25
申请号：US771889
申请日：1996-12-23
申请人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
发明人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
IPC分类号： B01J31/06 , A61K47/32 , C08F20/36 , C08F212/36 , C08F220/20 , C08F220/34 , C08F220/36 , C08F220/56 , C08G18/64 , C08G18/72 , C12N11/08 , C08F26/02 , C08F126/02 , C08F226/02
CPC分类号： C08G18/728 , C08F20/36 , C08F220/36 , C08G18/6446 , C12N11/08 , Y10S530/815
摘要： Insoluble supports are prepared which possess high surface areas and efficiently dispersed isocyanate groups. These reactive supports are useful for covalently binding proteins which preferably are enzymes and provide catalysts for conducting organic reactions.
摘要翻译： 制备具有高表面积和有效分散的异氰酸酯基团的不溶性载体。 这些反应性支持物可用于共价结合蛋白质，其优选为酶并提供用于进行有机反应的催化剂。
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公开(公告)号：US5760152A
公开(公告)日：1998-06-02
申请号：US453316
申请日：1995-05-30
申请人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
发明人： Steven M. Heilmann , Gary J. Drtina , Louis C. Haddad , Frederick W. Hyde , Dean M. Moren , Robert A. Pranis
IPC分类号： B01J31/06 , A61K47/32 , C08F20/36 , C08F212/36 , C08F220/20 , C08F220/34 , C08F220/36 , C08F220/56 , C08G18/64 , C08G18/72 , C12N11/08 , C08F26/02
CPC分类号： C08G18/728 , C08F20/36 , C08F220/36 , C08G18/6446 , C12N11/08 , Y10S530/815
摘要： Insoluble supports are prepared which possess high surface areas and efficiently dispersed isocyanate groups. These reactive supports are useful for covalently binding proteins which preferably are enzymes and provide catalysts for conducting organic reactions.
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公开(公告)号：US20140033777A1
公开(公告)日：2014-02-06
申请号：US13967523
申请日：2013-08-15
申请人： Frederick J. Schendel , Marc von Keitz , Kenneth J. Valentas , Steven M. Heilmann , Lindsey R. Jader , Brandon M. Wood
发明人： Frederick J. Schendel , Marc von Keitz , Kenneth J. Valentas , Steven M. Heilmann , Lindsey R. Jader , Brandon M. Wood
CPC分类号： C05B17/00 , C05F5/008 , C05F11/02 , C10L5/44 , C10L5/447 , C10L9/086 , C10L2290/26 , C10L2290/543 , Y02A40/212 , Y02E50/10 , Y02E50/30
摘要： The present invention concerns a process for producing synthetic coal and aqueous liquid plant fertilizing solution products from a fermentation residue such as is left over from the corn based process of producing ethanol. The synthetic coal has a high heat value commensurate with naturally occurring coals and is lower in ash and sulfur content and thus has value as a clean burning energy source. The aqueous fertilizer includes commercially useful amounts of phosphorous, potassium and nitrogen in solution. The process of the invention is also energy efficient in that the products produced thereby involve the use of substantially less energy as compared to the traditional methods of processing fermentation residues in the corn based ethanol production industry.
摘要翻译： 本发明涉及一种生产合成煤和水性液体植物施肥溶液产品的方法，该发酵残渣例如从生产乙醇的基于玉米的方法遗留下来。 合成煤具有与天然煤相当的高热值，灰分和硫含量较低，因此具有清洁燃烧能源的价值。 含水肥料在溶液中包括商业上有用量的磷，钾和氮。 本发明的方法也是能量效率的，因为所生产的产品与传统的在玉米基乙醇生产工业中发酵残余物的加工方法相比使用的能量要少得多。
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8.发明申请SYNTHETIC COAL AND METHODS OF PRODUCING SYNTHETIC COAL FROM FERMENTATION RESIDUE 审中-公开合成煤和从发酵残渣生产合成煤的方法公开(公告)号：US20110271588A1
公开(公告)日：2011-11-10
申请号：US12941533
申请日：2010-11-08
申请人： Frederick J. Schendel , Marc von Keitz , Kenneth J. Valentas , Lindsey Jader , Steven M. Heilmann
发明人： Frederick J. Schendel , Marc von Keitz , Kenneth J. Valentas , Lindsey Jader , Steven M. Heilmann
IPC分类号： C10L5/00
摘要： Synthetic coal, methods of producing synthetic coal, produced from fermentation residue, such as the residue from ethanol production, by subjecting the fermentation residue to hydrothermal carbonization in an aqueous solution at a temperature and a pressure sufficient to form a synthetic coal solid and a liquid component. The solid synthetic coal component has a low ash content and may be used as a carbon source for energy production, such as for combustive thermal energy generation, or for gassification for the production of synthesis gas.
摘要翻译： 合成煤，由发酵残渣生产的合成煤的方法，例如乙醇生产的残留物，通过使发酵残渣在水溶液中在足以形成合成煤固体和液体的温度和压力下进行水热碳化 零件。 固体合成煤组分具有低灰分含量，并且可以用作能量产生的碳源，例如用于可燃热能产生或用于生产合成气的气化。
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公开(公告)号：US20110056124A1
公开(公告)日：2011-03-10
申请号：US12715595
申请日：2010-03-02
申请人： Steven M. Heilmann , Kenneth J. Valentas , Marc von Keitz , Frederick J. Schendel , Paul A. Lefebvre , Michael J. Sadowsky
发明人： Steven M. Heilmann , Kenneth J. Valentas , Marc von Keitz , Frederick J. Schendel , Paul A. Lefebvre , Michael J. Sadowsky
IPC分类号： C10L5/44
摘要： Algae-derived synthetic coal and filtrates. The invention described herein provides an algae-derived synthetic coal product and filtrates and process for preparing the same using an improved hydrothermal carbonization process. The synthetic coal product is similar to natural bituminous coal in terms of percent carbon content and energy equivalency while at the same time containing relatively low levels of sulfur and contaminant heavy metals. Unlike natural coal and other fossil fuels, because the carbon of the biomass is formed through photosynthesis, carbon dioxide formed during combustion is a “carbon neutral” event with little or no “new” carbon dioxide being added to the earth's atmosphere. The algae-derived filtrates contain useful constituents.
摘要翻译： 藻类衍生的合成煤和滤液。 本文描述的本发明提供了一种藻类衍生的合成煤产品和滤液，以及使用改进的水热碳化方法制备该产品的方法。 合成煤产品与碳含量和能量当量的百分比类似于天然烟煤，同时含有较低含量的硫和污染重金属。 与天然煤和其他化石燃料不同，由于生物质碳通过光合作用形成，燃烧过程中形成的二氧化碳是一种“碳中和”事件，几乎没有或没有将“新”二氧化碳加入到大气中。 藻类衍生的滤液含有有用成分。
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公开(公告)号：US07459489B2
公开(公告)日：2008-12-02
申请号：US11463103
申请日：2006-08-08
申请人： Kevin M. Lewandowski , Duane D. Fansler , Michael S. Wendland , Steven M. Heilmann , Babu N. Gaddam
发明人： Kevin M. Lewandowski , Duane D. Fansler , Michael S. Wendland , Steven M. Heilmann , Babu N. Gaddam
CPC分类号： C08G65/329 , A61L15/22 , C08F265/04 , C08F283/06 , C08F291/00 , C08F293/005 , C08L51/003 , C08L51/006 , C08L51/08 , C08L71/02 , C09D151/003 , C09D151/006 , C09D151/08 , C08L2666/02
摘要： Hydrophilic compositions are described, which are prepared from a first oligomer containing pendent polymerizable groups and pendent hydrophilic groups, crosslinked with a co-reactive second component oligomer possessing photoinitiator groups. The compositions may be used as in preparation of hydrophilic gel coatings or layers for medical devices.
摘要翻译： 描述了亲水性组合物，其由包含侧链可聚合基团和侧链亲水基团的第一低聚物制备，与具有光引发剂基团的共反应性第二组分低聚物交联。 组合物可用于制备用于医疗装置的亲水凝胶涂层或层。
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