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    Interstitial fluid methods and devices for determination of an analyte in the body
    1.
    发明授权
    Interstitial fluid methods and devices for determination of an analyte in the body 有权
    用于测定体内分析物的组织液方法和装置

    公开(公告)号：US06251083B1

    公开(公告)日：2001-06-26

    申请号：US09391002

    申请日：1999-09-07

    申请人： Su I. Yum ,  Jeffrey N. Roe ,  Joel S. Douglas

    发明人： Su I. Yum ,  Jeffrey N. Roe ,  Joel S. Douglas

    IPC分类号： A61B500

    CPC分类号： A61B5/14514 ,  A61B5/14532

    摘要： Devices and methods for utilizing dry chemistry dye indicator systems for body fluid analysis, such as glucose level provided by incorporating a porous membrane in a disposable patch. The devices also provide for microtitration of fluid samples in fixed volumetric openings containing indicator reagent. The devices provided are low cost due to efficient manufacturing methods provided.

    摘要翻译： 用于使用干化学染料指示剂系统进行体液分析的装置和方法，例如通过将多孔膜并入一次性贴片而提供的葡萄糖水平。 该装置还提供含有指示剂试剂的固定体积开口中的液体样品的微量滴定。 所提供的装置由于提供的有效制造方法而成本低。

    Body fluid sampling device and methods of use
    3.
    发明授权
    Body fluid sampling device and methods of use 有权
    体液取样装置及使用方法

    公开(公告)号：US07901363B2

    公开(公告)日：2011-03-08

    申请号：US10753973

    申请日：2004-01-08

    申请人： Brent G. Duchon ,  Joel S. Douglas ,  Jeffrey N. Roe ,  Ryszard Radwanski ,  Andrew M. Drexler

    发明人： Brent G. Duchon ,  Joel S. Douglas ,  Jeffrey N. Roe ,  Ryszard Radwanski ,  Andrew M. Drexler

    IPC分类号： A61B5/00

    CPC分类号： A61B10/0045 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150717 ,  A61B5/150824 ,  A61B5/15111 ,  A61B5/15117 ,  A61B5/1513 ,  A61B5/1519 ,  A61B5/15194 ,  A61B2010/008 ,  A61B2017/00765 ,  A61B2562/0295

    摘要： A device for sampling body fluid includes a housing having a sleeve at a forward end thereof which is displaceable in response to being pressed against a user's skin to trigger the firing of a lancet. After the lancet is removed from the incision, the sleeve is repeatedly pressed against the skin to depress a ring of body tissue in surrounding relationship to the incision to express body fluid outwardly through the incision. A pusher member is then actuated to push a capillary tube through a front end of the housing for drawing-in body fluid. The lancet is a disposable lancet which includes a body supporting a skin-lancing member and the capillary tube. The disposable lancet passes through an upper end of a lancet carrier when being installed or removed. The device cannot be armed until the disposable lancet is installed in the housing, because the capillary tube functions to push a safety device to a non-safety position.

    摘要翻译： 用于体液取样的装置包括：壳体，其在其前端具有套筒，该壳体可响应于压靠使用者的皮肤而移位，以触发刺血针的点燃。 在从切口中取出刺血针之后，套筒被重复地压在皮肤上，以与切口围绕的关系压下身体组织环，以通过切口向外表达体液。 然后致动推动器构件以推动毛细管穿过壳体的前端以吸入体液。 柳叶刀是一次性的柳叶刀，其包括支撑皮肤穿刺部件和毛细管的主体。 当安装或拆卸时，一次性柳叶刀穿过柳叶刀托架的上端。 由于毛细管的作用是将安全装置推到非安全位置，因此该装置将不会挂起，直到一次性的柳叶刀安装在外壳中。

    Electrochemical test device and related methods
    6.
    发明授权
    Electrochemical test device and related methods 失效

    公开(公告)号：US07018848B2

    公开(公告)日：2006-03-28

    申请号：US10224875

    申请日：2002-08-21

    申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  John H. Priest

    发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  John H. Priest

    IPC分类号： G01N33/551

    CPC分类号： C12Q1/001 ,  C12Q1/004 ,  C12Q1/006 ,  Y10S435/817 ,  Y10S436/805 ,  Y10S436/806

    摘要： An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode. The test device electrodes can be constructed on a flexible film substrate, such as a polymeric film or a metal foil coated with a non-conductive coating.

    METHODS AND APPARATUS FOR EXPRESSING BODY FLUID FROM AN INCISION
    9.
    发明申请
    METHODS AND APPARATUS FOR EXPRESSING BODY FLUID FROM AN INCISION 审中-公开
    用于从体内表达体液的方法和装置

    公开(公告)号：US20110046515A1

    公开(公告)日：2011-02-24

    申请号：US12938784

    申请日：2010-11-03

    申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  Henry M. Grage

    发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  Henry M. Grage

    IPC分类号： A61B5/151

    CPC分类号： A61B5/15194 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150083 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B10/0045 ,  A61B2010/008 ,  A61B2017/00765 ,  A61B2562/0295

    摘要： A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.

    摘要翻译： 体液例如血液或间质液的样品通过使用者的皮肤的一部分优选在指尖以外的区域穿刺而从身体获得，以形成切口。 在针从切口移除之后，施加力以形成与切口周围关系的形成凹陷的身体组织的环的方式来压下皮肤，导致切口凸起并且切口的两侧打开，由此 体液通过切口的开口被迫出来。 刺激构件安装到用于施加力的刺血针承载壳体的端部。 刺激器构件可以相对于壳体可移动，并且可以被加热或振动以促进体液的移动。