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23 条记录 (耗时 0.04 秒)

    Methods of modulating the activity of TANGO332
    1.
    发明授权
    Methods of modulating the activity of TANGO332 失效
    调节TANGO332活性的方法

    公开(公告)号：US08076086B2

    公开(公告)日：2011-12-13

    申请号：US11499835

    申请日：2006-08-04

    申请人： Susan J. Kirst ,  Douglas A. Holtzman ,  Christopher C. Fraser ,  John D. Sharp ,  Thomas S. Barnes

    发明人： Susan J. Kirst ,  Douglas A. Holtzman ,  Christopher C. Fraser ,  John D. Sharp ,  Thomas S. Barnes

    IPC分类号： G01N33/53 ,  A61K38/00 ,  C07K17/00

    CPC分类号： C07K16/18 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/47 ,  C07K16/28 ,  G01N33/5058

    摘要： The invention provides isolated nucleic acids encoding a variety of proteins and nucleic acids having diagnostic, preventive, therapeutic, and other uses. These nucleic acids and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.

    摘要翻译： 本发明提供编码具有诊断，预防，治疗和其它用途的各种蛋白质和核酸的分离的核酸。 这些核酸和蛋白质可用于诊断，预防和治疗许多人类和其他动物疾病。 本发明还提供反义核酸分子，含有本发明的核酸分子的表达载体，已经引入了表达载体的宿主细胞和其中引入了本发明的核酸分子的非人转基因动物，或 中断了 本发明还进一步提供分离的多肽，融合多肽，抗原肽和抗体。 还提供了利用本发明组合物的诊断，筛选和治疗方法。 本发明的核酸和多肽可用作调节各种细胞过程的调节剂。

    TANGO 332 polypeptides
    2.
    发明授权
    TANGO 332 polypeptides 失效
    TANGO 332多肽

    公开(公告)号：US06960651B2

    公开(公告)日：2005-11-01

    申请号：US10188495

    申请日：2002-07-02

    申请人： Susan J. Kirst ,  Douglas A. Holtzman ,  Christopher C. Fraser ,  John D. Sharp ,  Thomas S. Barnes

    发明人： Susan J. Kirst ,  Douglas A. Holtzman ,  Christopher C. Fraser ,  John D. Sharp ,  Thomas S. Barnes

    IPC分类号： A61K38/00 ,  C07K14/47 ,  A61K39/00

    CPC分类号： C07K16/18 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/47 ,  C07K16/28 ,  G01N33/5058

    摘要： The invention provides isolated nucleic acids encoding a variety of proteins and nucleic acids having diagnostic, preventive, therapeutic, and other uses. These nucleic acids and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.

    摘要翻译： 本发明提供编码具有诊断，预防，治疗和其它用途的各种蛋白质和核酸的分离的核酸。 这些核酸和蛋白质可用于诊断，预防和治疗许多人类和其他动物疾病。 本发明还提供反义核酸分子，含有本发明的核酸分子的表达载体，已经引入了表达载体的宿主细胞和其中引入了本发明的核酸分子的非人转基因动物，或 中断了 本发明还进一步提供分离的多肽，融合多肽，抗原肽和抗体。 还提供了利用本发明组合物的诊断，筛选和治疗方法。 本发明的核酸和多肽可用作调节各种细胞过程的调节剂。