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1.发明申请Phospholipases, Nucleic Acids Encoding Them and Methods for Making and Using Them 有权磷脂酶，编码它们的核酸及其制备和使用方法公开(公告)号：US20080317731A1
公开(公告)日：2008-12-25
申请号：US10592450
申请日：2005-03-08
申请人： Svetlana Gramatikova , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Andrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
发明人： Svetlana Gramatikova , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Andrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
IPC分类号： A61K38/43 , C12N15/11 , C12N15/00 , C12N5/06 , C12N1/20 , C12N1/19 , C12N5/04 , A01K67/027 , A01H5/00 , C12N9/99 , C12N9/20 , C12N11/00 , C40B40/10 , C07K16/18 , G01N33/573 , C12P21/04 , C12Q1/44 , G06F19/00 , A61P43/00 , A61K31/7088 , C07H1/00 , C12P19/34 , C40B50/06 , C12Q1/68 , C11C1/00 , C11D7/42 , D06M16/00 , C10G32/00 , C12P7/64
CPC分类号： C12N15/8242 , C07K2319/00 , C12N9/16 , C12N9/18 , C12N9/20 , C12N15/8247 , C12P7/6418 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, phosphatidic acid phosphatases (PAP)) and/or lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，磷脂酸磷酸酶（PAP））和/或脂质酰基水解酶（LAH）活性，编码它们的核酸和抗体 绑定到他们。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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2.发明授权Phospholipases, nucleic acids encoding them and methods for making and using them 有权磷脂酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US07226771B2
公开(公告)日：2007-06-05
申请号：US10796907
申请日：2004-03-08
IPC分类号： C12N9/18
CPC分类号： C12N15/8242 , C07K2319/00 , C12N9/16 , C12N9/18 , C12N9/20 , C12N15/8247 , C12P7/6418 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，脂质酰基水解酶（LAH）活性，编码它们的核酸和与它们结合的抗体。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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3.发明授权Phospholipases, nucleic acids encoding them and methods for making and using them 有权磷脂酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US07943360B2
公开(公告)日：2011-05-17
申请号：US11625765
申请日：2007-01-22
申请人： Svetlana Gramatikova , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
发明人： Svetlana Gramatikova , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
CPC分类号： C12N9/16 , C07K2319/00 , C12N9/18 , C12N9/20 , C12N15/8242 , C12N15/8247 , C12P7/6418 , C12P7/6445 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，脂质酰基水解酶（LAH）活性，编码它们的核酸和与它们结合的抗体。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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4.发明授权Phospholipases, nucleic acids encoding them and methods for making and using them 有权磷脂酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US07977080B2
公开(公告)日：2011-07-12
申请号：US10592450
申请日：2005-03-08
申请人： Svetlana Gramatikova , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
发明人： Svetlana Gramatikova , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
CPC分类号： C12N15/8242 , C07K2319/00 , C12N9/16 , C12N9/18 , C12N9/20 , C12N15/8247 , C12P7/6418 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, phosphatidic acid phosphatases (PAP)) and/or lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，磷脂酸磷酸酶（PAP））和/或脂质酰基水解酶（LAH）活性，编码它们的核酸和抗体 绑定到他们。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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5.发明申请公开(公告)号：US20090053191A1
公开(公告)日：2009-02-26
申请号：US11625765
申请日：2007-01-22
申请人： Svetlana GRAMATIKOVA , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
发明人： Svetlana GRAMATIKOVA , Geoff Hazlewood , David Lam , Nelson R. Barton , Blake G. Sturgis , Dan E. Robertson , Jincai Li , Joel A. Kreps , Roderick James Fielding , Robert C. Brown , Amit Vasavada , Xuqiu Tan , Adrian Badillo , Wilhelmus P. Van Hoek , Giselle Janssen , Charles Isaac , Mark J. Burk
IPC分类号： A61K38/46 , C12N15/11 , C07H21/04 , C12P19/34 , C12P21/04 , C12N15/00 , C12N1/20 , C12N5/06 , C12N1/19 , C12N5/04 , A01K67/027 , A01H5/00 , C07H21/02 , C12N9/20 , C12N11/14 , C40B40/10 , C12N11/08 , C07K16/18 , G06F19/00 , C11D7/42 , C11D3/386 , C12N15/82 , C12P7/64 , C10G32/00 , A61K31/7088 , A61K38/00 , C12Q1/44
CPC分类号： C12N9/16 , C07K2319/00 , C12N9/18 , C12N9/20 , C12N15/8242 , C12N15/8247 , C12P7/6418 , C12P7/6445 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，脂质酰基水解酶（LAH）活性，编码它们的核酸和与它们结合的抗体。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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6.发明申请Phosholipases, nucleic acids encoding them and methods for making and using them 有权磷脂酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US20050108789A1
公开(公告)日：2005-05-19
申请号：US10796907
申请日：2004-03-08
CPC分类号： C12N15/8242 , C07K2319/00 , C12N9/16 , C12N9/18 , C12N9/20 , C12N15/8247 , C12P7/6418 , C12P7/6481
摘要： The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
摘要翻译： 本发明提供具有磷脂酶活性的新型多肽，包括例如磷脂酶A，B，C和D活性，patatin活性，脂质酰基水解酶（LAH）活性，编码它们的核酸和与它们结合的抗体。 还提供了工业方法，例如油脱胶，以及包含使用这些磷脂酶的产品。
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7.发明授权Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US07504120B2
公开(公告)日：2009-03-17
申请号：US10463720
申请日：2003-06-16
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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8.发明授权Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US08728769B2
公开(公告)日：2014-05-20
申请号：US12402421
申请日：2009-03-11
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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9.发明申请Xylanases, Nucleic Acids Encoding Them and Methods for Making and Using Them 有权木聚糖酶，编码它们的核酸及其制备和使用方法公开(公告)号：US20130337507A1
公开(公告)日：2013-12-19
申请号：US13835743
申请日：2013-03-15
申请人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
发明人： Brian Steer , Walter Callen , Shaun Healey , Geoff Hazlewood , Di Wu , David Blum , Alireza Esteghlalian
IPC分类号： C12N9/24
CPC分类号： C12N9/248 , A01K2217/05 , C07K2319/00 , C07K2319/02 , C12N9/2434 , C12N9/2482 , C12P19/14 , C12Y302/01008 , D21C5/005 , D21H17/005 , Y02E50/16 , Y02E50/17
摘要： The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及木聚糖酶和编码木聚糖酶的多核苷酸。 此外，还提供了设计新的木聚糖酶的方法及其使用方法。 木聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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10.发明申请AMYLASES AND GLUCOAMYLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权琥珀酸和谷氨酰胺，编码它们的核酸及其制备和使用它们的方法公开(公告)号：US20110039308A1
公开(公告)日：2011-02-17
申请号：US12520523
申请日：2007-12-21
申请人： Malgorzata Slupska , Geoff Hazlewood , Cathy Chang , Peter Luginbuhl , Ellen Burke , Michelle Cayouette , Uvini Gunavardena , Majid Ghassemian , Aron Silverstone , Yan Zhang
发明人： Malgorzata Slupska , Geoff Hazlewood , Cathy Chang , Peter Luginbuhl , Ellen Burke , Michelle Cayouette , Uvini Gunavardena , Majid Ghassemian , Aron Silverstone , Yan Zhang
IPC分类号： C12P19/04 , C10L1/00 , A23L1/28 , C12P7/04 , C12P7/16 , C12P7/06 , C12N9/26 , C12N9/34 , C12N5/10 , C12N15/63 , C40B50/00 , C07H21/04 , C10L1/224
CPC分类号： C12N9/96 , C12N9/2408 , C12N9/2414 , C12N9/2425 , C12N9/2428 , Y02E50/16 , Y02E50/17
摘要： In one aspect, the invention is directed to polypeptides having an amylase and/or glucoamylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of polysaccharide, oligosaccharide or starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating. In alternative embodiments, enzymes are used to make biofuels, e.g., ethanol, butanol, propanol, or a gasoline-ethanol mix, including a bioethanol, biopropanol, biobutanol, or a biodiesel, or for any form of fuel or biomass processing.
摘要翻译： 一方面，本发明涉及具有淀粉酶和/或葡糖淀粉酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 一方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化多糖，寡糖或淀粉水解成糖。 一方面，本发明提供包含通过胶乳聚合物涂层涂覆的所需成分的延迟释放组合物。 在替代实施方案中，酶用于制备生物燃料，例如乙醇，丁醇，丙醇或汽油 - 乙醇混合物，包括生物乙醇，生物丙醇，生物丁醇或生物柴油，或用于任何形式的燃料或生物质处理。
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