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    Injector Assemblies and Microreactors Incorporating The Same
    4.
    发明申请
    Injector Assemblies and Microreactors Incorporating The Same 有权
    注射器组件和包含它的微反应器

    公开(公告)号：US20090297410A1

    公开(公告)日：2009-12-03

    申请号：US12396114

    申请日：2009-03-02

    申请人： Olivier Lobet ,  Stephane Poissy ,  Pierre Woehl

    发明人： Olivier Lobet ,  Stephane Poissy ,  Pierre Woehl

    IPC分类号： B01J10/00 ,  B01L5/00

    CPC分类号： B01J19/0093 ,  B01F3/0446 ,  B01F5/0077 ,  B01F5/045 ,  B01J4/002 ,  B01J2219/0081 ,  B01J2219/0086 ,  B01J2219/00891 ,  B05B7/0433

    摘要： A microreactor assembly (100) is provided comprising a fluidic microstructure (10) and an injector assembly (20). The injector assembly (20) comprises a liquid inlet (22), a gas inlet (24), a liquid outlet (26), a gas outlet (28), a liquid flow portion (30) extending from the liquid inlet (22) to the liquid outlet (26), and a gas flow portion (40) extending from the gas inlet (24) to the gas outlet (28). Further, the injector assembly (20) defines an injection interface with a microchannel input port (14) of the fluidic microstructure (10). The injector assembly (20) is configured such that the gas outlet (28) of the gas flow portion (40) is positioned to inject gas into the liquid flow portion (30) upstream of the liquid outlet (26), into the liquid flow portion (30) at the liquid outlet (26), or into an extension (35) of the liquid flow portion (30) downstream of the liquid outlet (26). Further, the injector assembly (20) is configured such that gas is injected into the liquid flow portion (30) or the extension thereof as a series of gas bubbles. The resulting microreactor assembly (100), and the injector assemblies utilized therein, which can be used with a variety of microreactor designs, effectively improves the interfacial surface area within the microstructure without requiring excessive reduction of microchannel dimensions.

    摘要翻译： 提供了包括流体微结构（10）和喷射器组件（20）的微反应器组件（100）。 喷射器组件（20）包括液体入口（22），气体入口（24），液体出口（26），气体出口（28），从液体入口（22）延伸的液体流动部分（30） 到液体出口（26）和从气体入口（24）延伸到气体出口（28）的气体流动部分（40）。 此外，喷射器组件（20）限定与流体微结构（10）的微通道输入端口（14）的注入界面。 喷射器组件（20）构造成使得气体流动部分（40）的气体出口（28）定位成将气体喷射到液体出口（26）上游的液体流动部分（30）中，进入液体流 在液体出口（26）处的部分（30），或液体出口（26）下游的液体流动部分（30）的延伸部（35）中。 此外，喷射器组件（20）构造成使得气体作为一系列气泡被喷射到液体流动部分（30）或其延伸部分中。 可以与各种微反应器设计一起使用的所得微反应器组件（100）和其中使用的喷射器组件有效地改善了微结构内的界面表面积，而不需要过度减小微通道尺寸。

    Injector assemblies and microreactors incorporating the same
    5.
    发明授权
    Injector assemblies and microreactors incorporating the same 有权
    引入组件和包括其的微反应器

    公开(公告)号：US08101128B2

    公开(公告)日：2012-01-24

    申请号：US12396114

    申请日：2009-03-02

    申请人： Olivier Lobet ,  Stephane Poissy ,  Pierre Woehl

    发明人： Olivier Lobet ,  Stephane Poissy ,  Pierre Woehl

    IPC分类号： B01J19/00 ,  B01J8/00 ,  B01J10/00

    CPC分类号： B01J19/0093 ,  B01F3/0446 ,  B01F5/0077 ,  B01F5/045 ,  B01J4/002 ,  B01J2219/0081 ,  B01J2219/0086 ,  B01J2219/00891 ,  B05B7/0433

    摘要： A microreactor assembly is provided comprising a fluidic microstructure and an injector assembly. The injector assembly comprises a liquid inlet, a gas inlet, a liquid outlet, a gas outlet, a liquid flow portion extending from the liquid inlet to the liquid outlet, and a gas flow portion extending from the gas inlet to the gas outlet. Further, the injector assembly defines an injection interface with a microchannel input port of the fluidic microstructure. The injector assembly is configured such that the gas outlet of the gas flow portion is positioned to inject gas into the liquid flow portion upstream of the liquid outlet, into the liquid flow portion at the liquid outlet, or into an extension of the liquid flow portion downstream of the liquid outlet and is configured such that gas is injected into the liquid flow portion or the extension thereof as a series of gas bubbles.

    摘要翻译： 提供了包括流体微结构和喷射器组件的微反应器组件。 喷射器组件包括液体入口，气体入口，液体出口，气体出口，从液体入口延伸到液体出口的液体流动部分，以及从气体入口延伸到气体出口的气体流动部分。 此外，喷射器组件限定了与流体显微组织的微通道输入端口的注入界面。 喷射器组件被构造成使得气体流动部分的气体出口定位成将气体注入到液体出口上游的液体流动部分中，在液体出口处进入液体流动部分，或者进入液体流动部分的延伸部分 在液体出口的下游并且被配置为使得气体作为一系列气泡注入到液体流动部分或其延伸部分中。

    Multiple flow path microreactor design
    7.
    发明授权
    Multiple flow path microreactor design 有权
    多流路微反应器设计

    公开(公告)号：US08534909B2

    公开(公告)日：2013-09-17

    申请号：US12568318

    申请日：2009-09-28

    申请人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： B01F5/06 ,  B01J19/00

    CPC分类号： B01F5/0641 ,  B01F5/0603 ,  B01F5/061 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01F2005/0022 ,  B01F2005/0621 ,  B01F2005/0636 ,  B01L3/502746 ,  B01L2300/0816 ,  B01L2400/08 ,  B01L2400/086 ,  Y10T137/8593

    摘要： A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

    摘要翻译： 微流体装置包括由壁限定的至少一个反应物通道，并且包括至少一个平行的多个流动路径构造，其包括一组基本设计模式，其能够提供与流体连通串联布置的混合和/或停留时间，以便 构成流动路径并且并联，以便构成多流路基本设计模式，其中所述并行多流路构造包括在两个相邻的平行流动路径的基本设计模式之间的至少两个连通区域，所述连通区域是相同的 平面，如所述基本设计图案所限定的，所述基本设计图案位于所述连通区域之间，并且允许流体通过，以使具有相同流动方向的相邻平行流动路径之间的质量流量差最小化。

    Methods for scale-up of continuous reactors
    8.
    发明授权
    Methods for scale-up of continuous reactors 有权

    公开(公告)号：US10046295B2

    公开(公告)日：2018-08-14

    申请号：US14125720

    申请日：2012-06-07

    申请人： Roland Guidat ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： B01J19/00

    摘要： A method for scale-up of a micro reactor process from lab to production scale comprises using a wall material for a lab reactor having thermal conductivity ≤3 W/m·K, and using a wall material for a production reactor having thermal conductivity ≥5 W/m·K. Desirably, flow velocity is kept constant, and the height of the production-scale process channel is determined by: H G = 2 × ( A + B λ W + 1 C × ( D h ) ( b - 1 ) ) - 1 h = H G ⁢ ⁢ 0 wherein A B and C are constants; HG is the overall volumetric heat transfer coefficient, Dh is the hydraulic diameter, λW is the thermal conductivity of the wall, b is the empirically determined power to which the Reynolds number is raised in the equation for the Nusselt criteria (Nu=a·RebPrc) for the type of flow used, and h is the height of the channel, all in the production-scale process; and HG0 is the overall volumetric heat transfer coefficient in the lab-scale process.

    MULTIPLE FLOW PATH MICROREACTOR DESIGN
    10.
    发明申请
    MULTIPLE FLOW PATH MICROREACTOR DESIGN 有权
    多流程路径微处理器设计

    公开(公告)号：US20100078086A1

    公开(公告)日：2010-04-01

    申请号：US12568318

    申请日：2009-09-28

    申请人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： G01N35/00

    CPC分类号： B01F5/0641 ,  B01F5/0603 ,  B01F5/061 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01F2005/0022 ,  B01F2005/0621 ,  B01F2005/0636 ,  B01L3/502746 ,  B01L2300/0816 ,  B01L2400/08 ,  B01L2400/086 ,  Y10T137/8593

    摘要： A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

    摘要翻译： 微流体装置包括由壁限定的至少一个反应物通道，并且包括至少一个平行的多个流动路径构造，其包括一组基本设计模式，其能够提供与流体连通串联布置的混合和/或停留时间，以便 构成流动路径并且并联，以便构成多流路基本设计模式，其中所述并行多流路构造包括在两个相邻的平行流动路径的基本设计模式之间的至少两个连通区域，所述连通区域是相同的 平面，如所述基本设计图案所限定的，所述基本设计图案位于所述连通区域之间，并且允许流体通过，以使具有相同流动方向的相邻平行流动路径之间的质量流量差最小化。