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    Multiple flow path microreactor design
    4.
    发明授权
    Multiple flow path microreactor design 有权
    多流路微反应器设计

    公开(公告)号：US08534909B2

    公开(公告)日：2013-09-17

    申请号：US12568318

    申请日：2009-09-28

    申请人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： B01F5/06 ,  B01J19/00

    CPC分类号： B01F5/0641 ,  B01F5/0603 ,  B01F5/061 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01F2005/0022 ,  B01F2005/0621 ,  B01F2005/0636 ,  B01L3/502746 ,  B01L2300/0816 ,  B01L2400/08 ,  B01L2400/086 ,  Y10T137/8593

    摘要： A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

    摘要翻译： 微流体装置包括由壁限定的至少一个反应物通道，并且包括至少一个平行的多个流动路径构造，其包括一组基本设计模式，其能够提供与流体连通串联布置的混合和/或停留时间，以便 构成流动路径并且并联，以便构成多流路基本设计模式，其中所述并行多流路构造包括在两个相邻的平行流动路径的基本设计模式之间的至少两个连通区域，所述连通区域是相同的 平面，如所述基本设计图案所限定的，所述基本设计图案位于所述连通区域之间，并且允许流体通过，以使具有相同流动方向的相邻平行流动路径之间的质量流量差最小化。

    MULTIPLE FLOW PATH MICROREACTOR DESIGN
    5.
    发明申请
    MULTIPLE FLOW PATH MICROREACTOR DESIGN 有权
    多流程路径微处理器设计

    公开(公告)号：US20100078086A1

    公开(公告)日：2010-04-01

    申请号：US12568318

    申请日：2009-09-28

    申请人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： G01N35/00

    CPC分类号： B01F5/0641 ,  B01F5/0603 ,  B01F5/061 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01F2005/0022 ,  B01F2005/0621 ,  B01F2005/0636 ,  B01L3/502746 ,  B01L2300/0816 ,  B01L2400/08 ,  B01L2400/086 ,  Y10T137/8593

    摘要： A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

    摘要翻译： 微流体装置包括由壁限定的至少一个反应物通道，并且包括至少一个平行的多个流动路径构造，其包括一组基本设计模式，其能够提供与流体连通串联布置的混合和/或停留时间，以便 构成流动路径并且并联，以便构成多流路基本设计模式，其中所述并行多流路构造包括在两个相邻的平行流动路径的基本设计模式之间的至少两个连通区域，所述连通区域是相同的 平面，如所述基本设计图案所限定的，所述基本设计图案位于所述连通区域之间，并且允许流体通过，以使具有相同流动方向的相邻平行流动路径之间的质量流量差最小化。

    Methods for scale-up of continuous reactors
    8.
    发明授权
    Methods for scale-up of continuous reactors 有权

    公开(公告)号：US10046295B2

    公开(公告)日：2018-08-14

    申请号：US14125720

    申请日：2012-06-07

    申请人： Roland Guidat ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： B01J19/00

    摘要： A method for scale-up of a micro reactor process from lab to production scale comprises using a wall material for a lab reactor having thermal conductivity ≤3 W/m·K, and using a wall material for a production reactor having thermal conductivity ≥5 W/m·K. Desirably, flow velocity is kept constant, and the height of the production-scale process channel is determined by: H G = 2 × ( A + B λ W + 1 C × ( D h ) ( b - 1 ) ) - 1 h = H G ⁢ ⁢ 0 wherein A B and C are constants; HG is the overall volumetric heat transfer coefficient, Dh is the hydraulic diameter, λW is the thermal conductivity of the wall, b is the empirically determined power to which the Reynolds number is raised in the equation for the Nusselt criteria (Nu=a·RebPrc) for the type of flow used, and h is the height of the channel, all in the production-scale process; and HG0 is the overall volumetric heat transfer coefficient in the lab-scale process.

    SYSTEMS AND METHODS FOR SCALE-UP OF CONTINUOUS FLOW REACTORS
    9.
    发明申请
    SYSTEMS AND METHODS FOR SCALE-UP OF CONTINUOUS FLOW REACTORS 审中-公开
    连续流动反应器定标系统及方法

    公开(公告)号：US20140115871A1

    公开(公告)日：2014-05-01

    申请号：US14125720

    申请日：2012-06-07

    申请人： Roland Guidat ,  Olivier Lobet ,  Pierr Woehl

    发明人： Roland Guidat ,  Olivier Lobet ,  Pierr Woehl

    IPC分类号： B01J19/00

    CPC分类号： B01J19/0053 ,  B01J19/0093 ,  B01J2219/00015 ,  B01J2219/00824 ,  B01J2219/00831 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00995 ,  Y10T29/49

    摘要： A method is disclosed for the seamless scale-up of a micro reactor process, to transfer lab test to a pilot or production unit, the process comprising the steps of using a wall material for the lab reactor with a thermal conductivity lower than 3 W/m-K, and using a wall material for the production reactor with a thermal conductivity higher than 5 W/m-K. According to one preferred embodiment, the velocity is kept constant, and the height of the channel is determined, in order to keep the volumetric heat transfer properties constant, according to the formula: wherein HG is the overall volumetric heat transfer coefficient in the pilot or production process; A B and C are constants; Dh is the hydraulic diameter of the channel in the pilot or production process; λw is the thermal conductivity of the wall in the pilot or production process; b is the empirically determined power to which the Reynolds number is raised in the equation for the Nusselt criteria (Nu=a−RebPrc) for the type of flow in the pilot or production process; h is the height of the channel in the pilot or production process; and HG0 is the overall volumetric heat transfer coefficient in the lab-scale process.

    摘要翻译： 公开了一种用于微反应器过程的无缝放大以将实验室测试转移到先导或生产单元的方法，该方法包括以下步骤：使用导热率低于3W / mK，并且使用导热率高于5W / mK的生产反应器的壁材料。 根据一个优选实施例，速度保持恒定，并且确定通道的高度，以便保持体积传热性能恒定，其中HG是飞行员中的总体积传热系数，或 生产过程; A B和C是常数; Dh是先导或生产过程中通道的液压直径; λw是先导或生产过程中墙壁的导热系数; b是在试点或生产过程中的流量类型的努塞尔标准（Nu = a-RebPrc）的方程中提高雷诺数的经验确定的功率; h是飞行员或生产过程中通道的高度; HG0是实验室规模过程中的总体积传热系数。

    Heat exchanger and related exchange module
    10.
    发明授权
    Heat exchanger and related exchange module 有权
    热交换器及相关交换模块

    公开(公告)号：US07044207B1

    公开(公告)日：2006-05-16

    申请号：US10048371

    申请日：2000-07-26

    申请人： Roland Guidat ,  Michel Claudel ,  Florent Noel

    发明人： Roland Guidat ,  Michel Claudel ,  Florent Noel

    IPC分类号： F28F3/12 ,  B21D53/04

    CPC分类号： F28F3/14 ,  F28D9/0006 ,  F28D9/0031 ,  F28F9/005 ,  F28F9/0221 ,  F28F2250/102 ,  F28F2255/10

    摘要： A heat exchange module is disclosed comprising two metal sheets welded along weld lines defining between them a group of channels disposed side by side substantially in a common plane, intended to be passed through by an exchange fluid and, from the fluidic point of view, being in parallel with each other between two connection orifices of the module. The group of channels has a generally U-shape configuration, which connects together the said connection orifices that are laterally separated from each other.

    摘要翻译： 公开了一种热交换模块，其包括沿焊缝线焊接的两个金属板，在它们之间形成一组通道，这些通道大致在共同的平面内并排设置，用于通过交换流体通过，并且从流体的角度来看， 在模块的两个连接孔之间彼此并联。 通道组具有大致U形构造，其将所述连接孔连接在一起，所述连接孔彼此横向分离。