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    Multiple flow path microreactor design
    4.
    发明授权
    Multiple flow path microreactor design 有权
    多流路微反应器设计

    公开(公告)号：US08534909B2

    公开(公告)日：2013-09-17

    申请号：US12568318

    申请日：2009-09-28

    申请人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： B01F5/06 ,  B01J19/00

    CPC分类号： B01F5/0641 ,  B01F5/0603 ,  B01F5/061 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01F2005/0022 ,  B01F2005/0621 ,  B01F2005/0636 ,  B01L3/502746 ,  B01L2300/0816 ,  B01L2400/08 ,  B01L2400/086 ,  Y10T137/8593

    摘要： A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

    摘要翻译： 微流体装置包括由壁限定的至少一个反应物通道，并且包括至少一个平行的多个流动路径构造，其包括一组基本设计模式，其能够提供与流体连通串联布置的混合和/或停留时间，以便 构成流动路径并且并联，以便构成多流路基本设计模式，其中所述并行多流路构造包括在两个相邻的平行流动路径的基本设计模式之间的至少两个连通区域，所述连通区域是相同的 平面，如所述基本设计图案所限定的，所述基本设计图案位于所述连通区域之间，并且允许流体通过，以使具有相同流动方向的相邻平行流动路径之间的质量流量差最小化。

    MULTIPLE FLOW PATH MICROREACTOR DESIGN
    5.
    发明申请
    MULTIPLE FLOW PATH MICROREACTOR DESIGN 有权
    多流程路径微处理器设计

    公开(公告)号：US20100078086A1

    公开(公告)日：2010-04-01

    申请号：US12568318

    申请日：2009-09-28

    申请人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Elena Daniela Lavric ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： G01N35/00

    CPC分类号： B01F5/0641 ,  B01F5/0603 ,  B01F5/061 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01F2005/0022 ,  B01F2005/0621 ,  B01F2005/0636 ,  B01L3/502746 ,  B01L2300/0816 ,  B01L2400/08 ,  B01L2400/086 ,  Y10T137/8593

    摘要： A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

    摘要翻译： 微流体装置包括由壁限定的至少一个反应物通道，并且包括至少一个平行的多个流动路径构造，其包括一组基本设计模式，其能够提供与流体连通串联布置的混合和/或停留时间，以便 构成流动路径并且并联，以便构成多流路基本设计模式，其中所述并行多流路构造包括在两个相邻的平行流动路径的基本设计模式之间的至少两个连通区域，所述连通区域是相同的 平面，如所述基本设计图案所限定的，所述基本设计图案位于所述连通区域之间，并且允许流体通过，以使具有相同流动方向的相邻平行流动路径之间的质量流量差最小化。

    Methods for scale-up of continuous reactors
    7.
    发明授权
    Methods for scale-up of continuous reactors 有权

    公开(公告)号：US10046295B2

    公开(公告)日：2018-08-14

    申请号：US14125720

    申请日：2012-06-07

    申请人： Roland Guidat ,  Olivier Lobet ,  Pierre Woehl

    发明人： Roland Guidat ,  Olivier Lobet ,  Pierre Woehl

    IPC分类号： B01J19/00

    摘要： A method for scale-up of a micro reactor process from lab to production scale comprises using a wall material for a lab reactor having thermal conductivity ≤3 W/m·K, and using a wall material for a production reactor having thermal conductivity ≥5 W/m·K. Desirably, flow velocity is kept constant, and the height of the production-scale process channel is determined by: H G = 2 × ( A + B λ W + 1 C × ( D h ) ( b - 1 ) ) - 1 h = H G ⁢ ⁢ 0 wherein A B and C are constants; HG is the overall volumetric heat transfer coefficient, Dh is the hydraulic diameter, λW is the thermal conductivity of the wall, b is the empirically determined power to which the Reynolds number is raised in the equation for the Nusselt criteria (Nu=a·RebPrc) for the type of flow used, and h is the height of the channel, all in the production-scale process; and HG0 is the overall volumetric heat transfer coefficient in the lab-scale process.

    FLUID CONNECTORS FOR MICROREACTOR MODULES
    10.
    发明申请
    FLUID CONNECTORS FOR MICROREACTOR MODULES 有权
    流体连接器用于微型模块

    公开(公告)号：US20130034475A1

    公开(公告)日：2013-02-07

    申请号：US13641323

    申请日：2011-04-12

    申请人： Pierre Brunello ,  Paul Louis Florent Delautre ,  Sylvain Maxime F. Gremetz ,  Olivier Lobet

    发明人： Pierre Brunello ,  Paul Louis Florent Delautre ,  Sylvain Maxime F. Gremetz ,  Olivier Lobet

    IPC分类号： B01L99/00

    CPC分类号： B01J19/0093 ,  B01J2219/0081 ,  B01L3/502715 ,  B01L3/563 ,  B01L3/569 ,  B01L2200/027

    摘要： An end-face sealing fluidic connector [20] for fluidic connection and/or interconnection of glass, glass-ceramic and/or ceramic fluidic modules [12] in a microreactor [10] and includes a connector body [22] having a circular first end face [26] with a recess [28] for retaining one or more O-rings [30]. The connector body [22] has a first end section [32] having a circular cylindrical outer surface [34] having a diameter [36] in the range of from 3 to 25 mm extending along the connector body [22] from the first end face [26]. The outer surface [34] of the first end section [32] is having a circumferential recess [38] dividing the first end section [32] into a proximal portion [40] adjacent the first end face [26] and a distal portion [42] separated from the proximal portion [40] by the circumferential recess [38]. A retaining ring [48] is seated in the circumferential recess and a circular cylindrical circumferential reinforcing and/or protecting ring [50] surrounds the proximal portion [40] of the first end section [32], the ring [50] being comprised of a high-compression-strength polymer. A circular cylindrical sleeve [58] surrounds the first end section [32] and the reinforcing and/or protecting ring [50], the sleeve [58] including a circumferentially extending inside bearing surface for engaging the retaining ring [48] on the distal side thereof. The circular cylindrical sleeve [58] further comprises an external thread [66] on a proximal outer surface [68] thereof and a gripping surface [70] on a distal outer surface [72] thereof.

    摘要翻译： 用于在微反应器[10]中的玻璃，玻璃 - 陶瓷和/或陶瓷流体模块[12]的流体连接和/或互连的端面密封流体连接器[20]，并且包括连接器本体[22] 端面[26]具有用于保持一个或多个O形环[30]的凹部[28]。 连接器主体[22]具有第一端部部分32，其具有从第一端部沿着连接器主体[22]延伸的直径[36]在3至25mm范围内的圆柱形外表面[34] 脸[26]。 第一端部部分[32]的外表面[34]具有将第一端部部分[32]分成邻近第一端面[26]的近端部分[40]的周向凹部[38] 42]通过周向凹部[38]与近侧部分[40]分离。 保持环[48]位于周向凹槽中，并且环形圆周周向增强和/或保护环围绕第一端部[32]的近端部分[40]，环[50]包括 高压缩强度聚合物。 环形圆柱形套筒围绕第一端部部分[32]和加强和/或保护环[50]，套筒（58）包括周向延伸的内部支承表面，用于将保持环[48]接合在远端 侧。 圆柱形套筒[58]还包括在其近端外表面[68]上的外螺纹[66]和位于其远侧外表面[72]上的抓握表面[70]。