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公开(公告)号：US20160310927A1
公开(公告)日：2016-10-27
申请号：US15135434
申请日：2016-04-21
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE , Eugene P. MARSH
IPC: B01J19/00
CPC classification number: B01J19/0046 , B01J2219/00317 , B01J2219/00497 , B01J2219/00511 , B01J2219/00522 , B01J2219/00585 , B01J2219/00596 , B01J2219/00635 , B01J2219/00637 , B01J2219/00662 , B01J2219/00722 , B01L3/50857 , C12N15/1093 , C12Q2563/159 , C12Q2565/513 , C12Q2565/629
Abstract: Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
Abstract translation: 本文提供了用于从头合成大量和高精度的寡核酸文库的装置和方法。 器件包括具有主通道和微通道的结构，其中微通道具有高表面积与体积比。 本文公开的装置提供具有低错误率的寡核酸的从头合成。
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公开(公告)号：US20160251651A1
公开(公告)日：2016-09-01
申请号：US15156134
申请日：2016-05-16
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE
IPC: C12N15/10
CPC classification number: C12N15/1093 , C12Q1/6806 , C12Q2521/501 , C12Q2525/179 , C12Q2525/191 , C12Q2525/204 , C12Q2525/307 , C12Q2527/143 , C12Q2531/113 , C12Q2535/122 , C12Q2563/149 , C12Q2563/159 , C12Q2565/626 , C12Q2531/125
Abstract: Methods and devices for cell-free sorting and cloning of nucleic acid libraries are provided herein.
Abstract translation: 本文提供了用于无细胞分选和克隆核酸文库的方法和装置。
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公开(公告)号：US20230127969A1
公开(公告)日：2023-04-27
申请号：US18047228
申请日：2022-10-17
Applicant: Twist Bioscience Corporation
Inventor： Jeremy LACKEY , William BANYAI
IPC: C12Q1/6869
Abstract: Provided herein are compositions, devices, systems and methods for polynucleotide sequencing. Further provided are devices comprising surfaces for continuous sequencing. The compositions, devices, systems and methods described herein provide improved storage, density, and retrieval of biomolecule-based information.
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公开(公告)号：US20160354752A1
公开(公告)日：2016-12-08
申请号：US15245054
申请日：2016-08-23
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE
IPC: B01J19/00
CPC classification number: B01J19/0046 , B01J2219/00313 , B01J2219/00317 , B01J2219/00378 , B01J2219/00497 , B01J2219/00585 , B01J2219/00587 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00619 , B01J2219/00623 , B01J2219/00637 , B01J2219/00709 , B01J2219/00722 , C12N15/09 , C12N15/1093 , C12N15/1096 , C12N15/66 , C12N15/74 , C40B40/06 , C40B50/00 , C40B50/14 , C40B50/18
Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
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公开(公告)号：US20160096160A1
公开(公告)日：2016-04-07
申请号：US14885963
申请日：2015-10-16
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE
IPC: B01J19/00
CPC classification number: B01J19/0046 , B01J2219/00313 , B01J2219/00317 , B01J2219/00378 , B01J2219/00497 , B01J2219/00585 , B01J2219/00587 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00619 , B01J2219/00623 , B01J2219/00637 , B01J2219/00709 , B01J2219/00722 , C12N15/09 , C12N15/1093 , C12N15/1096 , C12N15/66 , C12N15/74 , C40B40/06 , C40B50/00 , C40B50/14 , C40B50/18
Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
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Patent Agency Ranking
公开(公告)号：US20230338913A1
公开(公告)日：2023-10-26
申请号：US18319356
申请日：2023-05-17
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE , Eugene P. MARSH
CPC classification number: B01J19/0046 , C12N15/1093 , B01J2219/00596 , B01J2219/00722 , B01J2219/00497 , B01J2219/00585 , B01J2219/00317 , B01J2219/00511 , B01J2219/00522 , B01J2219/00635 , B01J2219/00637 , B01J2219/00662 , B01L3/50857
Abstract: Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
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公开(公告)号：US20220325276A2
公开(公告)日：2022-10-13
申请号：US15156134
申请日：2016-05-16
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE , Cheng-Hsien WU , Esteban TORO
IPC: C12N15/10
Abstract: Methods and devices for cell-free sorting and cloning of nucleic acid libraries are provided herein.
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公开(公告)号：US20160090592A1
公开(公告)日：2016-03-31
申请号：US14885962
申请日：2015-10-16
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE
IPC: C12N15/10
CPC classification number: B01J19/0046 , B01J2219/00313 , B01J2219/00317 , B01J2219/00378 , B01J2219/00497 , B01J2219/00585 , B01J2219/00587 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00619 , B01J2219/00623 , B01J2219/00637 , B01J2219/00709 , B01J2219/00722 , C12N15/09 , C12N15/1093 , C12N15/1096 , C12N15/66 , C12N15/74 , C40B40/06 , C40B50/00 , C40B50/14 , C40B50/18
Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
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公开(公告)号：US20160089651A1
公开(公告)日：2016-03-31
申请号：US14885965
申请日：2015-10-16
Applicant: TWIST BIOSCIENCE CORPORATION
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE
IPC: B01J19/00
CPC classification number: B01J19/0046 , B01J2219/00313 , B01J2219/00317 , B01J2219/00378 , B01J2219/00497 , B01J2219/00585 , B01J2219/00587 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00619 , B01J2219/00623 , B01J2219/00637 , B01J2219/00709 , B01J2219/00722 , C12N15/09 , C12N15/1093 , C12N15/1096 , C12N15/66 , C12N15/74 , C40B40/06 , C40B50/00 , C40B50/14 , C40B50/18
Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
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公开(公告)号：US20230211308A1
公开(公告)日：2023-07-06
申请号：US18067652
申请日：2022-12-16
Applicant: Twist Bioscience Corporation
Inventor： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE
CPC classification number: B01J19/0046 , C12N15/1093 , C40B50/18 , C12N15/66 , C12N15/1096 , C12N15/74 , B01J2219/00722 , B01J2219/00596 , B01J2219/0059 , B01J2219/00587 , C40B50/00
Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
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