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131 条记录 (耗时 0.037 秒)

    Preventives or remedies for vision disorders
    2.
    发明授权
    Preventives or remedies for vision disorders 失效
    视力障碍的预防或补救措施

    公开(公告)号：US06268359B1

    公开(公告)日：2001-07-31

    申请号：US09601216

    申请日：2000-07-28

    申请人： Takahiro Ogawa ,  Noriko Watanabe ,  Mitsunori Waki

    发明人： Takahiro Ogawa ,  Noriko Watanabe ,  Mitsunori Waki

    IPC分类号： A61K3155

    CPC分类号： A61K31/00 ,  A61K31/55

    摘要： A pharmaceutical composition for preventing or treating visual function disorders caused by ocular circulatory disorders (for example, ocular hypertension and glaucoma) and visual function disorders based on ciliary tension (for example, myopia) whose active component is a vasopressin antagonist.

    摘要翻译： 一种用于预防或治疗由眼部循环障碍（例如眼睛高血压和青光眼）引起的视觉功能障碍的药物组合物和基于睫状肌张力的视觉功能障碍（例如近视），其活性成分是血管加压素拮抗剂。

    Method for controlling axial length of the eye
    3.
    发明授权
    Method for controlling axial length of the eye 失效
    控制眼睛轴向长度的方法

    公开(公告)号：US6010699A

    公开(公告)日：2000-01-04

    申请号：US815941

    申请日：1997-03-13

    申请人： Shigeru Honda ,  Noriko Watanabe ,  Takahiro Ogawa

    发明人： Shigeru Honda ,  Noriko Watanabe ,  Takahiro Ogawa

    IPC分类号： A61K38/49 ,  A61K38/57 ,  A61P27/10 ,  A61K38/16

    CPC分类号： A61K38/49 ,  A61K38/57

    摘要： A method for controlling axial length, comprising administering a pharmaceutically effective amount of a TGF-.beta. regulating substance. More particularly, a method for inhibiting axial elongation and a method for the prophylaxis and treatment of myopia, both comprising administering a TGF-.beta. activator, specifically a plasminogen activator. A method for elongation of axial length and a method for the prophylaxis and treatment of hyperopia, both comprising administering a TGF-.beta. activation inhibitor, particularly a plasminogen activator inhibitor. The method for controlling axial length of the present invention is extremely useful for the prophylaxis and treatment of myopia or hyperopia. It is also useful for preparing experimental model animals having eyes with complete axial myopia or hyperopia exclusive of refractive myopia or hyperopia.

    摘要翻译： 一种用于控制轴向长度的方法，包括施用药学上有效量的TGF-β调节物质。 更具体地说，一种抑制轴向伸长的方法和一种预防和治疗近视的方法，包括给予TGF-β激活剂，特别是施用纤溶酶原激活剂。 一种延长轴向长度的方法和一种预防和治疗远视的方法，其包括施用TGF-β激活抑制剂，特别是纤溶酶原激活物抑制剂。 用于控制本发明的轴向长度的方法对于预防和治疗近视或远视非常有用。 制备具有完全轴向近视或远视的实验模型动物，不包括屈光性近视或远视。

    Drugs for ameliorating ocular circulatory disorders
    4.
    发明授权
    Drugs for ameliorating ocular circulatory disorders 失效
    用于改善眼部循环障碍的药物

    公开(公告)号：US06451799B1

    公开(公告)日：2002-09-17

    申请号：US09297197

    申请日：1999-04-27

    申请人： Takahiro Ogawa ,  Noriko Watanabe ,  Mitsunori Waki

    发明人： Takahiro Ogawa ,  Noriko Watanabe ,  Mitsunori Waki

    IPC分类号： A61K3150

    CPC分类号： A61K31/4439 ,  A61K31/496 ,  A61K31/551 ,  Y10S514/912 ,  Y10S514/913

    摘要： An agent for ameliorating ocular circulatory disorder containing a 1,4-dihydropyridine derivative of the formula (I) wherein each symbol is as defined in the specification, or an acid addition salt thereof as an active ingredient. The agent for ameliorating ocular circulatory disorder containing the compound of the above formula (I) increases optic disc blood flow of normal eye particularly by instillation, and inhibits vasocontraction of retinal blood vessel, decrease in optic disc blood flow and attenuation of the amplitude of VEP caused by ET-1, without increasing the intraocular pressure. Therefore, the inventive compound is suggested to be effective as a therapeutic agent against, from among the types of glaucoma, particularly normal tension glaucoma caused by ocular circulation disorder and retinitis pigmentosa, macular degeneration, ischemic optic neuropathy, iridocyclitis, retinal artery occlusion, retinal vein occlusion, diabetic retinopathy, ischemic optic neuropathy, retinochoroidal disease following choroidal lesion, retinochoroidal disease associated with systemic disease, and the like.

    摘要翻译： 一种用于改善含有式（I）的1,4-二氢吡啶衍生物的眼部循环障碍的药剂，其中每个符号如说明书中所定义，或其酸加成盐作为活性成分。 用于改善含有上述式（I）化合物的眼部循环障碍的药物特别是通过滴注增加正常眼的视盘血流量，并且抑制视网膜血管的血管收缩，视盘血流的减少和VEP的振幅衰减 由ET-1引起，不增加眼内压。 因此，本发明化合物被认为是有效的，作为青光眼的类型，特别是由眼部循环障碍和色素性视网膜炎引起的正常的紧张性青光眼，黄斑变性，缺血性视神经病，虹膜睫状体炎，视网膜动脉闭塞，视网膜 静脉闭塞，糖尿病性视网膜病变，缺血性视神经病变，脉络膜损伤后的视网膜下疾病，与全身性疾病相关的视网膜激素疾病等。

    Agent for prophylaxis and treatment of disturbance of visual function
    6.
    发明授权
    Agent for prophylaxis and treatment of disturbance of visual function 失效
    用于预防和治疗视功能障碍的药剂

    公开(公告)号：US5952338A

    公开(公告)日：1999-09-14

    申请号：US886270

    申请日：1997-07-01

    申请人： Toshiharu Tsuboi ,  Noriko Watanabe ,  Takahiro Ogawa ,  Mitsuyoshi Isaka ,  Mitsunori Waki

    发明人： Toshiharu Tsuboi ,  Noriko Watanabe ,  Takahiro Ogawa ,  Mitsuyoshi Isaka ,  Mitsunori Waki

    IPC分类号： A61K31/436 ,  A61K31/44

    CPC分类号： A61K31/436 ,  Y10S514/912

    摘要： An agent for the prophylaxis and treatment of disturbance of visual function, which comprises a compound of the formula �I! ##STR1## wherein A ring is optionally substituted;R.sub.1 is a hydrogen or an optionally protected amino; andR.sub.2 is a group capable of releasing a proton,or a salt thereof. The agent for the prophylaxis and treatment of disturbance of visual function of the present invention has superior preventive and therapeutic effect on asthenopia, and shows suppression of axial elongation, suppression of degradation of retinal functions and retinal function-recovery action. Hence, the agent can be advantageously used as a clinically applicable agent for the prophylaxis and treatment of disturbance of visual function.

    摘要翻译： 一种用于预防和治疗视功能紊乱的药剂，其包含其中A环任选被取代的式[I]化合物; R1是氢或任选被保护的氨基; R2是能够释放质子的基团，或其盐。 本发明的预防和治疗视功能紊乱的药剂对眼疲劳具有优异的预防和治疗作用，并且显示出轴向伸长的抑制，抑制视网膜功能退化和视网膜功能恢复作用。 因此，该试剂可以有利地用作临床适用的预防和治疗视功能障碍的药剂。

    Substrate holding apparatus, substrate holding method, and substrate processing apparatus
    8.
    发明授权
    Substrate holding apparatus, substrate holding method, and substrate processing apparatus 有权
    基板保持装置，基板保持方法和基板处理装置

    公开(公告)号：US08777198B2

    公开(公告)日：2014-07-15

    申请号：US13398216

    申请日：2012-02-16

    申请人： Masahiko Sekimoto ,  Seiji Katsuoka ,  Naoki Dai ,  Teruyuki Watanabe ,  Takahiro Ogawa ,  Kenichi Suzuki ,  Kenichi Kobayashi ,  Yasuyuki Motoshima ,  Ryo Kato

    发明人： Masahiko Sekimoto ,  Seiji Katsuoka ,  Naoki Dai ,  Teruyuki Watanabe ,  Takahiro Ogawa ,  Kenichi Suzuki ,  Kenichi Kobayashi ,  Yasuyuki Motoshima ,  Ryo Kato

    IPC分类号： B23Q1/00

    CPC分类号： H01L21/67086 ,  H01L21/67051 ,  H01L21/687

    摘要： A substrate holding apparatus can meet the request for a smaller-sized compact apparatus while ensuring a sufficient immersion depth of a substrate in a processing liquid. The substrate holding apparatus includes: a substrate holder for supporting a substrate (W) by bringing a peripheral portion of a surface of the substrate (W) into contact with a first sealing member; and a substrate pressing section for lowering relative to the substrate holder so as to press the substrate (W) held by the substrate holder downward, thereby bringing a first sealing member into pressure contact with the substrate (W). The substrate pressing section is provided with a second ring-shaped sealing member which makes pressure contact with an upper surface of a ring-shaped holding section of the substrate holder, thereby sealing the peripheral region of the substrate pressing section.

    摘要翻译： 基板保持装置可以满足对较小尺寸的小型装置的要求，同时确保基板在处理液体中的足够的浸入深度。 基板保持装置包括：基板保持件，用于通过使基板（W）的表面的周边部分与第一密封构件接触来支撑基板（W）; 以及基板按压部，其相对于基板保持件下降，以将由基板保持件保持的基板（W）向下压，从而使第一密封部件与基板（W）压力接触。 基板按压部设置有与基板保持件的环状保持部的上表面压力接触的第二环状密封部件，从而密封基板按压部的周边区域。

    Anti-shake apparatus
    10.
    发明授权
    Anti-shake apparatus 有权
    防抖装置

    公开(公告)号：US07796873B2

    公开(公告)日：2010-09-14

    申请号：US12044102

    申请日：2008-03-07

    申请人： Yukio Uenaka ,  Takahiro Ogawa

    发明人： Yukio Uenaka ,  Takahiro Ogawa

    IPC分类号： G03B17/00

    CPC分类号： H04N5/23248 ,  H04N5/23287

    摘要： An anti-shake apparatus (an image-stabilization apparatus) of a photographing device comprises a movable unit and a controller. The movable unit has an imaging device and is movable and rotatable for an anti-shake operation. The controller controls the movable unit for the anti-shake operation. The controller calculates a hand-shake angle caused by roll. The controller controls whether the anti-shake operation is performed for correcting hand-shake caused by roll, on the basis of the hand-shake angle caused by roll.

    摘要翻译： 拍摄装置的防抖装置（图像稳定装置）包括可移动单元和控制器。 可移动单元具有成像装置，并且可移动并且可旋转以进行防抖操作。 控制器控制可动单元进行防抖操作。 控制器计算由滚动导致的手抖动角度。 控制器根据由滚动导致的手抖动角度来控制是否执行用于校正由滚动导致的手抖动的防抖操作。