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    Gain control circuit
    1.
    发明授权
    Gain control circuit 失效
    增益控制电路

    公开(公告)号：US4101841A

    公开(公告)日：1978-07-18

    申请号：US829244

    申请日：1977-08-30

    申请人： Shigeru Okada ,  Takao Arai ,  Kouichi Tomatsuri ,  Hiroshi Toeda

    发明人： Shigeru Okada ,  Takao Arai ,  Kouichi Tomatsuri ,  Hiroshi Toeda

    IPC分类号： H03G1/04 ,  H03G3/30 ,  H03G7/00

    CPC分类号： H03G7/001 ,  H03G1/04 ,  H03G3/3005

    摘要： Disclosed is a gain control circuit which comprises a gain control section including as its essential component a differential amplifier with which diodes or transistors arranged to act as diodes are connected as a load, and a control signal section including a logarithmic compression circuit and an exponential expansion circuit and providing a control signal for control of the gain of the gain control section. A temperature compensation circuit having a temperature dependence cancelling both the temperature dependence of the gain control section and that of the control signal section is provided in the bias circuit for the transistor in the last stage of the control signal section, so that the desired temperature compensation for the entire gain control circuit can be achieved at a single point.

    Gain control circuit
    2.
    发明授权
    Gain control circuit 失效
    增益控制电路

    公开(公告)号：US4134078A

    公开(公告)日：1979-01-09

    申请号：US823198

    申请日：1977-08-09

    申请人： Takao Arai ,  Shigeru Okada ,  Kouichi Tomatsuri ,  Hiroshi Toeda

    发明人： Takao Arai ,  Shigeru Okada ,  Kouichi Tomatsuri ,  Hiroshi Toeda

    IPC分类号： H03G3/10 ,  H03G1/00 ,  H03G3/30

    CPC分类号： H03G1/0052

    摘要： A gain control circuit comprising a pair of transistors constituting a differential amplifier, and a pair of resistors each connected to the emitter of one of the transistors and having a sufficiently great resistance value compared with 1/gm of the transistor in the transistor operating range, the resistors being connected to a common regulated current supply to supply the halves of control current from the regulated current supply to the respective transistors, a pair of diodes are connected to the collectors of the respective transistors as a load, and a first variable resistor means is disposed in the current path traced from the diodes to the regulated current supply via the transistors and resistors for compensating fluctuation of the diffused resistance of the diodes. Further, a second variable resistor means is disposed in the base bias circuit for the transistors for compensating fluctuation of the base-emitter voltage of the transistors.

    摘要翻译： 一种增益控制电路，包括构成差分放大器的一对晶体管和一对电阻器，每个电阻器连接到晶体管之一的发射极，并且与晶体管工作范围内的晶体管的1 / gm相比具有足够大的电阻值， 电阻器连接到公共调节电流源，以将控制电流的一半从调节电流源提供给相应的晶体管，一对二极管作为负载连接到相应晶体管的集电极，第一可变电阻器装置 被布置在从二极管经由晶体管和电阻器调节的电流源的电流路径中，以补偿二极管扩散电阻的波动。 此外，第二可变电阻器装置设置在用于晶体管的基极偏置电路中，用于补偿晶体管的基极 - 发射极电压的波动。

    B. braunii, race B gene for a triterpene methyltransferase enzyme and uses thereof
    4.
    发明授权
    B. braunii, race B gene for a triterpene methyltransferase enzyme and uses thereof 有权

    公开(公告)号：US08487158B2

    公开(公告)日：2013-07-16

    申请号：US12489038

    申请日：2009-06-22

    申请人： Joseph Chappell ,  Shigeru Okada ,  Scott Kinison ,  Tom Niehaus

    发明人： Joseph Chappell ,  Shigeru Okada ,  Scott Kinison ,  Tom Niehaus

    IPC分类号： C12N15/29 ,  C12N15/52 ,  C12N15/82

    摘要： Provided is an isolated polypeptide having triterpene methyltransferase activity. Also provided is an isolated nucleic acid molecule that encodes the triterpene methyltransferase polypeptides; a vector comprising the nucleic acid molecules that encode the triterpene methyltransferase polypeptides; and a host cell(s) transfected with the aforementioned nucleic acid molecule or vector. In another aspect, a method of producing a methylated triterpene is provided. The method comprises providing a metabolizable carbon source to a host cell transfected with a nucleic acid molecule that encodes a triterpene methyltransferase under conditions sufficient for production of a methylated triterpene. The method optionally further comprises isolating the methylated triterpene produced by the host cell.

    PROTEIN ISOFORMS FOR DIAGNOSIS
    5.
    发明申请
    PROTEIN ISOFORMS FOR DIAGNOSIS 审中-公开
    用于诊断的蛋白质ISOFORMS

    公开(公告)号：US20110300641A1

    公开(公告)日：2011-12-08

    申请号：US12934807

    申请日：2009-03-27

    申请人： John J. Kopchick ,  Shigeru Okada ,  Sudha Sankaran

    发明人： John J. Kopchick ,  Shigeru Okada ,  Sudha Sankaran

    IPC分类号： G01N33/566 ,  C07K14/775 ,  H01J49/26 ,  C07K16/18 ,  G01N27/26 ,  G01N33/559 ,  C07K14/47 ,  C07K1/16

    CPC分类号： G01N27/44773 ,  C07K14/775 ,  G01N2800/042

    摘要： Several aspects of this invention relate to diagnosis of diabetic states in a mammal using protein isoforms. In some aspects, it relates to a method for determining the diabetic state of a mammal. This method can include, for example, (a) measuring the serum concentration of one or more protein isoforms, (b) analyzing the serum concentration of the one or more protein isoforms, and (c) determining the diabetic state of the mammal. Other aspects include kits used to perform the method. Further aspects are the isolated protein isoforms themselves, and their methods of isolation.

    摘要翻译： 本发明的几个方面涉及使用蛋白质同种型诊断哺乳动物中的糖尿病状态。 在一些方面，本发明涉及确定哺乳动物的糖尿病状态的方法。 该方法可以包括例如（a）测量一种或多种蛋白质同种型的血清浓度，（b）分析一种或多种蛋白质同种型的血清浓度，和（c）确定哺乳动物的糖尿病状态。 其他方面包括用于执行该方法的套件。 其他方面是分离的蛋白质异构体本身及其分离方法。

    Botryoccocus braunii triterpene synthase proteins and nucleic acid molecules, and methods for their use
    6.
    发明授权
    Botryoccocus braunii triterpene synthase proteins and nucleic acid molecules, and methods for their use 有权
    Botryoccocus braunii三萜合酶蛋白和核酸分子及其使用方法

    公开(公告)号：US07985568B2

    公开(公告)日：2011-07-26

    申请号：US12539442

    申请日：2009-08-11

    申请人： Joe Chappell ,  Shigeru Okada ,  Tom Niehaus ,  Tim Devarenne

    发明人： Joe Chappell ,  Shigeru Okada ,  Tom Niehaus ,  Tim Devarenne

    IPC分类号： C12P5/00

    CPC分类号： C12P5/007 ,  C12N9/1085

    摘要： This application relates to the functional identification and characterization of a nucleic acid molecule encoding a triterpene synthase, in particular botryococcene synthase. Also described are host cells comprising the nucleic acid molecules of this invention, proteins encoded by the nucleic acid molecules and methods for using the nucleic acid molecules, transformed hosts and encoded proteins to produce high levels of triterpene hydrocarbons.

    摘要翻译： 本申请涉及编码三萜合酶，特别是山梨酸合成酶的核酸分子的功能鉴定和表征。 还描述了包含本发明的核酸分子，由核酸分子编码的蛋白质和使用核酸分子，转化宿主和编码蛋白质以产生高水平三萜烷烃的方法的宿主细胞。

    B. BRAUNII, RACE B GENE FOR A TRITERPENE METHYLTRANSFERASE ENZYME AND USES THEREOF
    7.
    发明申请
    B. BRAUNII, RACE B GENE FOR A TRITERPENE METHYLTRANSFERASE ENZYME AND USES THEREOF 有权
    B.BRAUNII，RACE B基因的三磷酸甲酯衍生物酶及其用途

    公开(公告)号：US20100009423A1

    公开(公告)日：2010-01-14

    申请号：US12489038

    申请日：2009-06-22

    申请人： Joseph Chappell ,  Shigeru Okada ,  Scott Kinison ,  Tom Niehaus

    发明人： Joseph Chappell ,  Shigeru Okada ,  Scott Kinison ,  Tom Niehaus

    IPC分类号： C12P5/02 ,  C12N9/10 ,  C12N15/11 ,  C12N15/00 ,  C12N1/21 ,  C12N1/15 ,  C12N5/04 ,  C12N5/06 ,  C12N1/12

    CPC分类号： C12N9/1007 ,  C12N15/8243 ,  C12P5/007 ,  C12Y201/01

    摘要： Provided is an isolated polypeptide having triterpene methyltransferase activity. Also provided is an isolated nucleic acid molecule that encodes the triterpene methyltransferase polypeptides; a vector comprising the nucleic acid molecules that encode the triterpene methyltransferase polypeptides; and a host cell(s) transfected with the aforementioned nucleic acid molecule or vector. In another aspect, a method of producing a methylated triterpene is provided. The method comprises providing a metabolizable carbon source to a host cell transfected with a nucleic acid molecule that encodes a triterpene methyltransferase under conditions sufficient for production of a methylated triterpene. The method optionally further comprises isolating the methylated triterpene produced by the host cell.

    摘要翻译： 提供了具有三萜甲基转移酶活性的分离的多肽。 还提供了编码三萜甲基转移酶多肽的分离的核酸分子; 包含编码三萜甲基转移酶多肽的核酸分子的载体; 和用上述核酸分子或载体转染的宿主细胞。 另一方面，提供了生产甲基化三萜的方法。 该方法包括向在用于生产甲基化三萜烯的条件下编码三萜甲基转移酶的核酸分子转染的宿主细胞提供可代谢碳源。 所述方法任选进一步包括分离由宿主细胞产生的甲基化三萜烯。

    Water content sensing and informing system for a disposable diaper
    9.
    发明授权
    Water content sensing and informing system for a disposable diaper 失效
    一次性尿布的含水量感应和通报系统

    公开(公告)号：US4704108A

    公开(公告)日：1987-11-03

    申请号：US831288

    申请日：1986-02-20

    申请人： Shigeru Okada ,  Katsutoshi Rokuta

    发明人： Shigeru Okada ,  Katsutoshi Rokuta

    IPC分类号： A61F5/44 ,  A61F13/15 ,  A61F13/42 ,  A61F13/49 ,  A61B19/00

    CPC分类号： A61F5/4401 ,  A61F13/42

    摘要： Water content sensing and informing system for the disposable diaper composed of a water permeable inner sheet, a water absorber and a water impermeable outer sheet, comprises a water content sensing means consisting of a water impermeable sheet, and a first and second metal layers, the first metal layer being formed on one side surface of the water impermeable sheet, and the second metal layer being formed on the other side surface of the sheet and an informing means, electrically connected to the above two metal layers, for informing that the water content in the diaper exceeds a specific level in response to the change of the electric conductivity between the first metal layer and the second metal layer. The water content sensing means is disposed in any suitable section in the diaper such as in the water absorber, between the water absorber and the water impermeable outer sheet, or between the water absorber and the water permeable inner sheet and is adapted to be assembled with the diaper by means of a pressure welding or an adhesive at the same manufacturing process.

    摘要翻译： 由透水内层，吸水体和不透水外层构成的一次性尿布的含水量检测和通知系统包括由不透水片组成的含水量检测装置和第一和第二金属层， 第一金属层形成在不透水性片材的一个侧面上，第二金属层形成在片材的另一个侧面上，以及与上述两个金属层电连接的通知装置，用于通知含水量 在第一金属层和第二金属层之间的电导率的变化中，尿布超过特定水平。 水分检测装置设置在尿布中的任何合适的部分中，例如在吸水器，吸水器和不透水的外部片之间，或在吸水体和水可渗透的内层之间，并且适于与 该尿布通过压力焊接或粘合剂在相同的制造过程中。