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公开(公告)号：US20220288021A1
公开(公告)日：2022-09-15
申请号：US17625208
申请日：2020-07-10
Applicant: The Trustees of Princeton University
Inventor： John T. Groves , Micah T. Nelp
IPC: A61K31/404 , A61K47/18
Abstract: A method and compositions of matter for treating or preventing an auto-immune disorder or immune response in a patient, that includes providing a therapeutic dose to the patient of a substituted indole compound having at least one substitution, wherein the substituted indole compound has only one thiol group, and wherein the ring the thiol group is attached to only contains one N or O atom.
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2.发明授权公开(公告)号：US10974235B2
公开(公告)日：2021-04-13
申请号：US16702014
申请日：2019-12-03
Applicant: The Trustees of Princeton University
Inventor： John T. Groves , Xiongyi Huang
IPC: C07B59/00 , C07D213/643 , B01J31/18 , A61K51/04 , C07C41/22 , C07D319/20 , C07C49/80 , C07D209/48 , C07C69/65 , B01J31/22 , C07C67/287 , B01J31/02 , B01J31/04 , C07J1/00 , C07B39/00 , C07C17/363 , C07C45/67 , C07C49/813 , C07C43/225
Abstract: Methods of preparing fluorinated compounds by carboxylative fluorination using fluoride are contained herein. Fluorinated compounds are provided. Methods of using fluorinated compounds are contained herein.
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3.发明申请公开(公告)号：US20180037526A1
公开(公告)日：2018-02-08
申请号：US15549040
申请日：2016-02-09
Applicant: The Trustees of Princeton University
Inventor： John T. Groves , Xiongyi Huang
CPC classification number: C07C17/363 , B01J31/22 , B01J31/32 , C07B39/00 , C07B2200/05 , C07C22/08 , C07C23/46 , C07C41/22 , C07C45/676 , C07C67/297 , C07C253/30 , C07C255/35 , C07C2601/14 , C07C2603/74 , C07D209/46 , C07D209/48 , C07D319/20 , C07D333/12 , C07D493/18 , C07J1/0059 , C07C22/00 , C07C43/225 , C07C49/813 , C07C69/65
Abstract: Methods of preparing fluorinated compounds by carboxylative fluorination using fluoride are contained herein. Fluorinated compounds are provided. Methods of using fluorinated compounds are contained herein.
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4.发明授权公开(公告)号：US10414651B2
公开(公告)日：2019-09-17
申请号：US15228629
申请日：2016-08-04
Applicant: The Trustees of Princeton University
Inventor： John T. Groves , Roy Xiao
Abstract: Methods, kits, cartridges, and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of an iron porphyrin catalyst or an iron porphyrazine catalyst are described.
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公开(公告)号：US20190062255A1
公开(公告)日：2019-02-28
申请号：US16119125
申请日：2018-08-31
Inventor： Thomas Brent Gunnoe , George Fortman , Nicholas C. Boaz , John T. Groves
IPC: C07C67/035 , C10L1/02 , C07C29/00 , C07C29/147 , C07C19/03 , C07C19/043 , B01J19/24 , C07C17/00
CPC classification number: C07C67/035 , B01J19/123 , B01J19/127 , B01J19/24 , B01J2219/00051 , B01J2219/00162 , B01J2219/1278 , B01J2219/24 , C07C17/00 , C07C19/00 , C07C19/03 , C07C19/043 , C07C29/00 , C07C29/03 , C07C29/147 , C07C29/48 , C07C69/14 , C07C69/63 , C07C2602/42 , C07C2603/74 , C10L1/02 , C07C31/04 , C07C31/08 , C07C31/10
Abstract: Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like. Systems and methods as described herein can utilize photocatalysis.
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Patent Agency Ranking
公开(公告)号：US20170152207A1
公开(公告)日：2017-06-01
申请号：US15432380
申请日：2017-02-14
Inventor： Thomas Brent Gunnoe , George Fortman , Nicholas C. Boaz , John T. Groves
IPC: C07C67/035 , C07C19/03 , C07C19/043 , B01J19/24
CPC classification number: C07C67/035 , B01J19/24 , B01J2219/00051 , B01J2219/24 , C07C17/00 , C07C19/00 , C07C19/03 , C07C19/043 , C07C29/00 , C07C29/03 , C07C29/147 , C07C2602/42 , C07C2603/74 , C10L1/02 , C07C69/14 , C07C69/63
Abstract: Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like.
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公开(公告)号：US20150031768A1
公开(公告)日：2015-01-29
申请号：US14510509
申请日：2014-10-09
Applicant: The Trustees of Princeton University
Inventor： John T. Groves , Wei Liu , Xiongyi Huang
IPC: C07C211/42 , A61K31/198 , A61K31/192 , A61K31/135 , C07C57/30
CPC classification number: A61K31/198 , A61K31/135 , A61K31/192 , C07B39/00 , C07B2200/05 , C07C17/10 , C07C22/08 , C07C25/13 , C07C231/12 , C07C233/14 , C07C233/18 , C07C253/30 , C07C255/35 , C07C271/14 , C07C303/40 , C07C311/09 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/18 , C07C2602/42 , C07C2603/32 , C07C2603/74 , C07D209/48 , C07D215/18 , C07D217/20 , C07D231/12 , C07D333/28 , C07D333/54 , C07J11/00 , C07J63/008 , Y02P20/582 , C07C23/16 , C07C23/10 , C07C23/28 , C07C23/14 , C07C23/46
Abstract: Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided.
Abstract translation: 提供了具有sp 3 C-H键的含碳化合物的卤化方法。 提供了用Cl或Br氟化包含卤化的含碳化合物，然后用F进行亲核取代的方法。 提供了具有sp 3 C-H键的含碳化合物的直接氧化C-H氟化方法。 提供了这些方法的卤化产物。
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公开(公告)号：US09701557B2
公开(公告)日：2017-07-11
申请号：US14510543
申请日：2014-10-09
Applicant: The Trustees of Princeton University
Inventor： John T. Groves , Thomas P. Umile
IPC: C01B11/02 , C02F1/76 , C02F1/72 , B01J31/18 , C02F101/18
CPC classification number: C02F1/76 , B01J31/1815 , B01J2231/70 , B01J2531/025 , B01J2531/72 , C02F1/725 , C02F2101/18 , C02F2305/023
Abstract: Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described. Methods, kits, cartridges and compounds related to decomposed cyanide ions and hydrogen cyanide for water decontamination.
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公开(公告)号：US09604890B2
公开(公告)日：2017-03-28
申请号：US14900621
申请日：2014-06-26
Inventor： Thomas Brent Gunnoe , George Fortman , Nicholas C. Boaz , John T. Groves
IPC: C07C29/00 , C07C17/00 , C07C19/00 , C07C67/035 , B01J19/24 , C07C29/147 , C10L1/02 , C07C29/03
CPC classification number: C07C67/035 , B01J19/24 , B01J2219/00051 , B01J2219/24 , C07C17/00 , C07C19/00 , C07C19/03 , C07C19/043 , C07C29/00 , C07C29/03 , C07C29/147 , C07C2103/74 , C07C2602/42 , C07C2603/74 , C10L1/02 , C07C69/14 , C07C69/63
Abstract: Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like.
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10.发明公开公开(公告)号：US20240208815A1
公开(公告)日：2024-06-27
申请号：US18405407
申请日：2024-01-05
Applicant: THE TRUSTEES OF PRINCETON UNIVERSITY
Inventor： John T. Groves , Roy Xiao
IPC: C01B11/02 , A61L2/18 , B01J31/18 , B01J31/22 , B01J31/26 , C02F1/76 , C02F103/02 , C07F15/02 , D21C9/14
CPC classification number: C01B11/024 , A61L2/18 , B01J31/2295 , B01J31/26 , C07F15/025 , D21C9/14 , B01J31/1815 , B01J31/183 , B01J2531/025 , B01J2531/842 , C02F1/76 , C02F2103/023 , C02F2303/04
Abstract: Methods, kits, cartridges, and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of an iron porphyrin catalyst or an iron porphyrazine catalyst are described.
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