专利检索 ap:("The Trustees of Princeton University") AND inv:"John T. Groves" 第 1 页

1.

发明申请
METHOD AND COMPOUNDS FOR TREATING OR PREVENTING AUTOIMMUNE DISORDERS OR IMMUNE RESPONSES MODULATED BY THE EXPRESSION OF IDO1 有权

公开(公告)号：US20220288021A1

公开(公告)日：2022-09-15

申请号：US17625208

申请日：2020-07-10

申请人： The Trustees of Princeton University

发明人： John T. Groves , Micah T. Nelp

IPC分类号： A61K31/404 , A61K47/18

摘要： A method and compositions of matter for treating or preventing an auto-immune disorder or immune response in a patient, that includes providing a therapeutic dose to the patient of a substituted indole compound having at least one substitution, wherein the substituted indole compound has only one thiol group, and wherein the ring the thiol group is attached to only contains one N or O atom.

2.

发明授权
Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation 有权

公开(公告)号：US10974235B2

公开(公告)日：2021-04-13

申请号：US16702014

申请日：2019-12-03

申请人： The Trustees of Princeton University

发明人： John T. Groves , Xiongyi Huang

IPC分类号： C07B59/00 , C07D213/643 , B01J31/18 , A61K51/04 , C07C41/22 , C07D319/20 , C07C49/80 , C07D209/48 , C07C69/65 , B01J31/22 , C07C67/287 , B01J31/02 , B01J31/04 , C07J1/00 , C07B39/00 , C07C17/363 , C07C45/67 , C07C49/813 , C07C43/225

摘要： Methods of preparing fluorinated compounds by carboxylative fluorination using fluoride are contained herein. Fluorinated compounds are provided. Methods of using fluorinated compounds are contained herein.

3.

发明申请
TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION 审中-公开

公开(公告)号：US20180037526A1

公开(公告)日：2018-02-08

申请号：US15549040

申请日：2016-02-09

申请人： The Trustees of Princeton University

发明人： John T. Groves , Xiongyi Huang

IPC分类号： C07C17/363 , B01J31/32 , C07B39/00 , B01J31/22 , C07C22/08 , C07C23/46

CPC分类号： C07C17/363 , B01J31/22 , B01J31/32 , C07B39/00 , C07B2200/05 , C07C22/08 , C07C23/46 , C07C41/22 , C07C45/676 , C07C67/297 , C07C253/30 , C07C255/35 , C07C2601/14 , C07C2603/74 , C07D209/46 , C07D209/48 , C07D319/20 , C07D333/12 , C07D493/18 , C07J1/0059 , C07C22/00 , C07C43/225 , C07C49/813 , C07C69/65

摘要： Methods of preparing fluorinated compounds by carboxylative fluorination using fluoride are contained herein. Fluorinated compounds are provided. Methods of using fluorinated compounds are contained herein.

4.

发明授权
Iron porphyrazines as efficient, catalytic and scalable method to produce chlorine dioxide 有权

公开(公告)号：US10414651B2

公开(公告)日：2019-09-17

申请号：US15228629

申请日：2016-08-04

申请人： The Trustees of Princeton University

发明人： John T. Groves , Roy Xiao

IPC分类号： C01B11/02 , B01J31/22 , B01J31/26 , A61L2/18 , D21C9/14 , C07F15/02 , C02F1/76 , C02F103/02

摘要： Methods, kits, cartridges, and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of an iron porphyrin catalyst or an iron porphyrazine catalyst are described.

5.

发明申请
COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION 审中-公开

公开(公告)号：US20190062255A1

公开(公告)日：2019-02-28

申请号：US16119125

申请日：2018-08-31

申请人： University of Virginia Patent Foundation , The Trustees of Princeton University

发明人： Thomas Brent Gunnoe , George Fortman , Nicholas C. Boaz , John T. Groves

IPC分类号： C07C67/035 , C10L1/02 , C07C29/00 , C07C29/147 , C07C19/03 , C07C19/043 , B01J19/24 , C07C17/00

CPC分类号： C07C67/035 , B01J19/123 , B01J19/127 , B01J19/24 , B01J2219/00051 , B01J2219/00162 , B01J2219/1278 , B01J2219/24 , C07C17/00 , C07C19/00 , C07C19/03 , C07C19/043 , C07C29/00 , C07C29/03 , C07C29/147 , C07C29/48 , C07C69/14 , C07C69/63 , C07C2602/42 , C07C2603/74 , C10L1/02 , C07C31/04 , C07C31/08 , C07C31/10

摘要： Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like. Systems and methods as described herein can utilize photocatalysis.

6.

发明申请
COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION 审中-公开

公开(公告)号：US20170152207A1

公开(公告)日：2017-06-01

申请号：US15432380

申请日：2017-02-14

申请人： The University of Virginia Patent Foundation , The Trustees of Princeton University

发明人： Thomas Brent Gunnoe , George Fortman , Nicholas C. Boaz , John T. Groves

IPC分类号： C07C67/035 , C07C19/03 , C07C19/043 , B01J19/24

CPC分类号： C07C67/035 , B01J19/24 , B01J2219/00051 , B01J2219/24 , C07C17/00 , C07C19/00 , C07C19/03 , C07C19/043 , C07C29/00 , C07C29/03 , C07C29/147 , C07C2602/42 , C07C2603/74 , C10L1/02 , C07C69/14 , C07C69/63

摘要： Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like.

7.

发明申请
C-HALOGEN BOND FORMATION 审中-公开
标题翻译： C-HALOGEN BOND形成

公开(公告)号：US20150031768A1

公开(公告)日：2015-01-29

申请号：US14510509

申请日：2014-10-09

申请人： The Trustees of Princeton University

发明人： John T. Groves , Wei Liu , Xiongyi Huang

IPC分类号： C07C211/42 , A61K31/198 , A61K31/192 , A61K31/135 , C07C57/30

CPC分类号： A61K31/198 , A61K31/135 , A61K31/192 , C07B39/00 , C07B2200/05 , C07C17/10 , C07C22/08 , C07C25/13 , C07C231/12 , C07C233/14 , C07C233/18 , C07C253/30 , C07C255/35 , C07C271/14 , C07C303/40 , C07C311/09 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07C2602/10 , C07C2602/18 , C07C2602/42 , C07C2603/32 , C07C2603/74 , C07D209/48 , C07D215/18 , C07D217/20 , C07D231/12 , C07D333/28 , C07D333/54 , C07J11/00 , C07J63/008 , Y02P20/582 , C07C23/16 , C07C23/10 , C07C23/28 , C07C23/14 , C07C23/46

摘要： Methods of halogenating a carbon containing compound having an sp3 C—H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provided. Methods of direct oxidative C—H fluorination of a carbon containing compound having an sp3 C—H bond are provided. The halogenated products of the methods are provided.

摘要翻译： 提供了具有sp 3 C-H键的含碳化合物的卤化方法。提供了用Cl或Br氟化包含卤化的含碳化合物，然后用F进行亲核取代的方法。提供了具有sp 3 C-H键的含碳化合物的直接氧化C-H氟化方法。提供了这些方法的卤化产物。

8.

发明授权
Efficient, manganese catalyzed process to decompose cyanide ions and hydrogen cyanide for water decontamination 有权

公开(公告)号：US09701557B2

公开(公告)日：2017-07-11

申请号：US14510543

申请日：2014-10-09

申请人： The Trustees of Princeton University

发明人： John T. Groves , Thomas P. Umile

IPC分类号： C01B11/02 , C02F1/76 , C02F1/72 , B01J31/18 , C02F101/18

CPC分类号： C02F1/76 , B01J31/1815 , B01J2231/70 , B01J2531/025 , B01J2531/72 , C02F1/725 , C02F2101/18 , C02F2305/023

摘要： Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described. Methods, kits, cartridges and compounds related to decomposed cyanide ions and hydrogen cyanide for water decontamination.