公开(公告)号：US06743611B2

公开(公告)日：2004-06-01

申请号：US09842347

申请日：2001-04-25

申请人： Tohru Takahashi ,  Nobufusa Serizawa ,  Ryuta Koishi ,  Ichiro Kawashima

发明人： Tohru Takahashi ,  Nobufusa Serizawa ,  Ryuta Koishi ,  Ichiro Kawashima

IPC分类号： C12N902

CPC分类号： C12N9/0051 ,  A61K38/00 ,  C07K14/5431 ,  C07K2319/00 ,  C07K2319/35 ,  C07K2319/40 ,  C07K2319/50 ,  C07K2319/735 ,  C07K2319/75 ,  C07K2319/95 ,  C12N9/506 ,  C12N15/62

摘要： The present invention provides expression systems for exogenous polypeptides wherein the polypeptide is expressed as a fusion protein together with clover yellow virus Nuclear Inclusion a (NIa), the NIa component serving to autolyze the fusion protein after expression. This system can be used to express a novel polypeptide which we have designated KM31-7 protein and which is capable of reducing dichloroindophenol and reduced glutathione. This polypeptide is useful in the treatment of disorders caused by oxidative stress.

摘要翻译： 本发明提供用于外源多肽的表达系统，其中多肽与三叶草黄病毒核包涵a（NIa）一起表达为融合蛋白，其用于在表达后自动融合融合蛋白。 该系统可用于表达我们已经命名为KM31-7蛋白并能够还原二氯靛酚和还原型谷胱甘肽的新型多肽。 该多肽可用于治疗由氧化应激引起的疾病。

公开(公告)号：US06307038B1

公开(公告)日：2001-10-23

申请号：US09167151

申请日：1998-10-06

申请人： Tohru Takahashi ,  Nobufusa Serizawa ,  Ryuta Koishi ,  Ichiro Kawashima

发明人： Tohru Takahashi ,  Nobufusa Serizawa ,  Ryuta Koishi ,  Ichiro Kawashima

IPC分类号： C07H2104

CPC分类号： C12N9/0051 ,  A61K38/00 ,  C07K14/5431 ,  C07K2319/00 ,  C07K2319/35 ,  C07K2319/40 ,  C07K2319/50 ,  C07K2319/735 ,  C07K2319/75 ,  C07K2319/95 ,  C12N9/506 ,  C12N15/62

摘要： The present invention provides expression systems for exogenous polypeptides wherein the polypeptide is expressed as a fusion protein together with clover yellow virus Nuclear Inclusion a (NIa), the NIa component serving to autolyze the fusion protein after expression. This system can be used to express a novel polypeptide which we have designated KM31-7 protein and which is capable of reducing dichloroindophenol and reduced glutathione. This polypeptide is useful in the treatment of disorders caused by oxidative stress.

摘要翻译： 本发明提供用于外源多肽的表达系统，其中多肽与三叶草黄病毒核包涵a（NIa）一起表达为融合蛋白，其用于在表达后自动融合融合蛋白。 该系统可用于表达我们已经命名为KM31-7蛋白并能够还原二氯靛酚和还原型谷胱甘肽的新型多肽。 该多肽可用于治疗由氧化应激引起的疾病。

公开(公告)号：US5955072A

公开(公告)日：1999-09-21

申请号：US500635

申请日：1995-07-11

申请人： Tohru Takahashi ,  Nobufusa Serizawa ,  Ryuta Koishi ,  Ichiro Kawashima

发明人： Tohru Takahashi ,  Nobufusa Serizawa ,  Ryuta Koishi ,  Ichiro Kawashima

IPC分类号： C12N15/53 ,  A61K38/00 ,  A61K38/44 ,  A61K39/12 ,  A61P7/12 ,  A61P9/10 ,  C07K14/08 ,  C07K14/54 ,  C07K16/10 ,  C07K16/40 ,  C12N1/21 ,  C12N5/12 ,  C12N5/18 ,  C12N9/02 ,  C12N9/50 ,  C12N15/24 ,  C12N15/40 ,  C12N15/62 ,  C12N15/70 ,  C12Q1/68 ,  C12R1/19 ,  G01N33/573 ,  A61K38/43 ,  C07K1/00 ,  C12N9/48

CPC分类号： C12N9/0051 ,  C07K14/5431 ,  C12N15/62 ,  C12N9/506 ,  A61K38/00 ,  C07K2319/00 ,  C07K2319/35 ,  C07K2319/40 ,  C07K2319/50 ,  C07K2319/735 ,  C07K2319/75 ,  C07K2319/95

摘要： The present invention provides expression systems for exogenous polypeptides wherein the polypeptide is expressed as a fusion protein together with clover yellow virus Nuclear Inclusion a (NIa), the NIa component serving to autolyze the fusion protein after expression. This system can be used to express a novel polypeptide which we have designated KM31-7 protein and which is capable of reducing dichloroindophenol and reduced glutathione. This polypeptide is useful in the treatment of disorders caused by oxidative stress.

摘要翻译： 本发明提供用于外源多肽的表达系统，其中多肽与三叶草黄病毒核包涵a（NIa）一起表达为融合蛋白，其用于在表达后自动融合融合蛋白。 该系统可用于表达我们已经命名为KM31-7蛋白并能够还原二氯靛酚和还原型谷胱甘肽的新型多肽。 该多肽可用于治疗由氧化应激引起的疾病。

公开(公告)号：US06972323B1

公开(公告)日：2005-12-06

申请号：US09499662

申请日：2000-02-09

申请人： Nobufusa Serizawa ,  Kimihisa Ichikawa ,  Jun Ohsumi ,  Masahiko Ohtsuki ,  Hideyuki Haruyama ,  Tohru Takahashi ,  Hiroko Yoshida ,  Akio Shiraishi ,  Shin Yonehara

发明人： Nobufusa Serizawa ,  Kimihisa Ichikawa ,  Jun Ohsumi ,  Masahiko Ohtsuki ,  Hideyuki Haruyama ,  Tohru Takahashi ,  Hiroko Yoshida ,  Akio Shiraishi ,  Shin Yonehara

IPC分类号： A61K38/00 ,  C07K14/705 ,  C07K16/28

CPC分类号： C07K14/70575 ,  A61K38/00 ,  A61K2039/505 ,  C07K16/2878 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2319/00

摘要： Anti-Fas antibodies which are cross-reactive with mouse and human Fas and are useful in the treatment of conditions attributable to abnormalities in the Fas/Fas ligand system.

摘要翻译： 抗Fas抗体与小鼠和人Fas交叉反应，可用于治疗归因于Fas / Fas配体系统异常的病症。

公开(公告)号：US07894146B2

公开(公告)日：2011-02-22

申请号：US12844002

申请日：2010-07-27

申请人： Satoshi Komi ,  Tohru Takahashi

发明人： Satoshi Komi ,  Tohru Takahashi

IPC分类号： G02B7/02 ,  G03B21/14

CPC分类号： G02B7/02 ,  B29C65/14 ,  B29C65/1406 ,  B29C65/1435 ,  B29C65/1487 ,  B29C65/48 ,  B29C65/4845 ,  B29C66/5344 ,  B29L2011/0016 ,  G02B3/14

摘要： A liquid lens is mounted in a lens opening provided in a photographic instrument by making use of a mounting member made of a material which transmits light of predetermined wavelength and includes an inner wall shaped and dimensioned to receive the periphery of the lens in spaced, opposed relationship. The mounting member includes a portion mounted or to be mounted to the optical instrument. A bonding material is provided between the lens periphery and the mounting member wall, and the bonding material is activated by exposure to light of the predetermined wavelength, which is injected from outside, through the mounting member. Preferably, the light is injected with a guide member having an opening with an interior wall shaped and dimensioned to conform to an exterior wall of the guide member. The light may be injected from an edge of the guide member remote from the opening, through the guide member, and into the mounting member.

摘要翻译： 液体透镜通过使用由透射预定波长的光的材料制成的安装构件安装在设置在照相器具中的透镜开口中，该安装构件包括形状和尺寸的内壁，以便以间隔相对的方式接纳透镜的周边 关系。 安装构件包括安装或安装到光学仪器的部分。 在透镜周边和安装构件壁之间设置接合材料，并且通过暴露于从外部注入的预定波长的光通过安装构件来激活接合材料。 优选地，光被注入具有开口的引导构件，该引导构件的内壁的形状和尺寸被设计成符合引导构件的外壁。 光可以从引导构件的远离开口的边缘通过引导构件注入并进入安装构件。

公开(公告)号：US07383126B2

公开(公告)日：2008-06-03

申请号：US11142011

申请日：2005-06-01

申请人： Tohru Takahashi

发明人： Tohru Takahashi

IPC分类号： G01C21/30 ,  G08G1/123

CPC分类号： G01C21/3632 ,  G08G1/096861 ,  G08G1/0969

摘要： When the vehicle approaches an intersection, traffic signals located at the intersection are displayed on an intersection view, a traffic signal to be considered is displayed in a manner so as to be identifiable from the other traffic signals, arrows in the same directions as those of arrow signals for the traffic signal to be considered are displayed; and an arrow corresponding to an arrow signal permitting the vehicle to proceed in the direction of a guidance route is displayed in a manner so as to be identifiable from the other arrows.

摘要翻译： 当交通工具接近交叉路口时，交叉路口的交通信号显示在十字路口视图中，将要考虑的话务信号以与其他话务信号相同的方式显示，箭头与 显示要考虑的交通信号的箭头信号; 并且以与从其他箭头可识别的方式显示对应于允许车辆沿着引导路线的方向前进的箭头信号的箭头。

公开(公告)号：US20050273256A1

公开(公告)日：2005-12-08

申请号：US11142011

申请日：2005-06-01

申请人： Tohru Takahashi

发明人： Tohru Takahashi

IPC分类号： G09B29/00 ,  G01C21/00 ,  G01C21/30 ,  G01C21/36 ,  G08G1/0968 ,  G08G1/0969 ,  G08G1/123 ,  G09B29/10

CPC分类号： G01C21/3632 ,  G08G1/096861 ,  G08G1/0969

摘要： When the vehicle approaches an intersection, traffic signals located at the intersection are displayed on an intersection view, a traffic signal to be considered is displayed in a manner so as to be identifiable from the other traffic signals, arrows in the same directions as those of arrow signals for the traffic signal to be considered are displayed; and an arrow corresponding to an arrow signal permitting the vehicle to proceed in the direction of a guidance route is displayed in a manner so as to be identifiable from the other arrows.

摘要翻译： 当交通工具接近交叉路口时，交叉路口的交通信号显示在十字路口视图中，将要考虑的话务信号以与其他话务信号相同的方式显示，箭头与 显示要考虑的交通信号的箭头信号; 并且以与从其他箭头可识别的方式显示对应于允许车辆沿着引导路线的方向前进的箭头信号的箭头。

公开(公告)号：US5075855A

公开(公告)日：1991-12-24

申请号：US576076

申请日：1990-09-25

申请人： Fukashi Sugasawa ,  Ken Ito ,  Tohru Takahashi ,  Sadahiro Takahashi ,  Takeshi Fujishiro

发明人： Fukashi Sugasawa ,  Ken Ito ,  Tohru Takahashi ,  Sadahiro Takahashi ,  Takeshi Fujishiro

IPC分类号： B60G17/015 ,  B60G17/0165 ,  B60G17/019 ,  F16F9/46 ,  G01S15/88

CPC分类号： G01S15/88 ,  B60G17/0165 ,  B60G17/019 ,  B60G17/01941 ,  F16F9/467 ,  B60G2202/154 ,  B60G2202/42 ,  B60G2400/102 ,  B60G2400/106 ,  B60G2400/204 ,  B60G2400/252 ,  B60G2400/50 ,  B60G2400/60 ,  B60G2400/82 ,  B60G2400/821 ,  B60G2400/91 ,  B60G2401/10 ,  B60G2401/12 ,  B60G2401/176 ,  B60G2401/22 ,  B60G2500/102 ,  B60G2500/22 ,  B60G2600/02 ,  B60G2600/182 ,  B60G2600/184 ,  B60G2600/602 ,  B60G2600/604 ,  B60G2800/916

摘要： A suspension control system for automotive vehicles automatically adjusts the damping strength of variable shock absorbers or other dampers in accordance with road surface conditions as recognized by frequency analysis of a vehicle height or vibration sensor signal. The sensor signal reflects vertical displacement of the vehicle body from the road surface and includes high-frequency components due solely to displacement of the wheels or unsprung mass relative to the road surface and low-frequency components due to displacement of the vehicle body or sprung mass. The sensor signal is filtered into these separate frequency bands, the amplitude of each of which is compared to a corresponding reference level. The results of comparison give an indication of the degree and scale of irregularities in the road surface; specifically, a high-amplitude low-frequency component indicates larger-scale bumps and dips capable of bouncing the vehicle whereas a strong high-frequency component reflects a rough-textured road surface, such as gravel. The comparison information is sent to a suspension system controller which causes actuation of the shock absorbers to a stiffer mode of operation when the low-frequency sensor signal components are relatively strong.

公开(公告)号：US4906072A

公开(公告)日：1990-03-06

申请号：US105012

申请日：1987-10-06

申请人： Shuzo Kaneko ,  Tohru Takahashi

发明人： Shuzo Kaneko ,  Tohru Takahashi

IPC分类号： G09G3/36

CPC分类号： G09G3/3681 ,  G09G3/3629 ,  G09G2310/063

摘要： A driving apparatus suitable as, e.g., an electrode plate for an optical modulation device such as a liquid crystal device, comprises a conductor film, a plurality of voltage supply lines electrically connected to the conductor film respectively by the medium of a resistor, means for simultaneously applying a voltage signal to at least two voltage supply lines among the plurality of voltage supply lines, and means for changing a potential level provided to the conductor film defined between the at least two voltage supply lines.

摘要翻译： 适用于例如液晶装置等光调制装置的电极板的驱动装置包括：导体膜，分别通过电阻体的介质与导体膜电连接的多个电压供给线， 同时向所述多个电源线中的至少两个电压供给线施加电压信号，以及用于改变设置在所述至少两个电压供给线之间限定的所述导体膜的电位电平的装置。

公开(公告)号：US4806813A

公开(公告)日：1989-02-21

申请号：US027173

申请日：1987-03-17

申请人： Akiyasu Sumi ,  Shigeru Yoshida ,  Akira Kurosawa ,  Tohru Takahashi ,  Yoshitaka Kondoh ,  Tatsuo Chigira

发明人： Akiyasu Sumi ,  Shigeru Yoshida ,  Akira Kurosawa ,  Tohru Takahashi ,  Yoshitaka Kondoh ,  Tatsuo Chigira

IPC分类号： G02B7/08 ,  H02K29/08 ,  H02K1/12

CPC分类号： G02B7/08 ,  H02K29/08 ,  Y10S310/06

摘要： A motor comprises a rotor made of a permanent magnet and pairs of yokes having pairs of magnetic pole parts arranged round the circumference of the rotor. The rotor is arranged to be pivotally carried by a bearing part disposed at one end of the yoke. A position detecting element which detects the magnetic pole position of the rotor is carried by the yoke. An exciting coil is wound round each pair of the yokes.

摘要翻译： 电动机包括由永磁体制成的转子和成对的磁轭，所述磁轭具有绕转子圆周布置的磁极部对。 转子被布置成由设置在轭的一端的轴承部分枢转地承载。 检测转子的磁极位置的位置检测元件由轭支承。 励磁线圈缠绕在每对轭上。