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公开(公告)号：USRE36991E
公开(公告)日：2000-12-19
申请号：US375705
申请日：1999-08-13
申请人： Tomohiro Yamamoto , Mariko Miyashita , Toshihiko Yoshioka , Satoko Tsuji (nee Fujisawa) , Shiro Nankai
发明人： Tomohiro Yamamoto , Mariko Miyashita , Toshihiko Yoshioka , Satoko Tsuji (nee Fujisawa) , Shiro Nankai
CPC分类号： C12Q1/002 , C12Q1/001 , Y10S435/817
摘要： A biosensor for rapid quantification of a specific component contained in various biological samples with high accuracy has an electrically insulating base, an electrode system including a working electrode and a counter electrode formed on one face of the insulating base, and a reaction layer formed on the insulating base in close contact with the electrode system. The reaction layer contains at least a hydrophilic polymer, a buffer and an enzyme which is separated from the buffer.
摘要翻译： 用于以高精度快速定量包含在各种生物样品中的特定成分的生物传感器具有电绝缘基底，包括形成在绝缘基底的一个面上的工作电极和对电极的电极系统，以及形成在绝缘基底上的反应层 绝缘基座与电极系统紧密接触。 反应层至少含有亲水性聚合物，缓冲液和与缓冲液分离的酶。
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2.发明授权Sample treating kit and sample treating method using the same for analysis with a biosensor 失效样品处理试剂盒和使用该试剂处理方法的样品处理方法用于用生物传感器进行分析公开(公告)号：US06867002B2
公开(公告)日：2005-03-15
申请号：US09420719
申请日：1999-10-20
IPC分类号： C12Q1/00 , G01N33/53 , G01N33/543
CPC分类号： C12Q1/001 , Y10S436/825 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/25 , Y10T436/25125 , Y10T436/2525 , Y10T436/25375 , Y10T436/255
摘要： A sample solution treating instrument is provided for facilitating rapid and simplified adjustment of the condition of a sample solution proper for analysis with a biosensor before supplying the solution to the biosensor. The sample solution treating instrument includes, for example, a catalyst or an adsorbent which can remove any interfering substance in order to adjust the sample solution for measurement with a biosensor.
摘要翻译： 提供了一种样品溶液处理仪器，用于在将溶液供给生物传感器之前，利用生物传感器快速和简化调整适于分析的样品溶液的状况。 样品溶液处理仪器包括例如可以除去任何干扰物质的催化剂或吸附剂，以便通过生物传感器调节用于测量的样品溶液。
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公开(公告)号：US07741125B2
公开(公告)日：2010-06-22
申请号：US10550150
申请日：2005-02-02
IPC分类号： G01N33/18
CPC分类号： C12Q1/001 , B01L3/502715 , B01L3/502746 , B01L2200/143 , B01L2300/0645 , B01L2300/0825 , B01L2300/0887 , B01L2300/105 , B01L2400/0406 , G01N31/22
摘要： A biosensor and a biosensor measuring apparatus whose performance can be easily determined by an ordinary user are provided. A biosensor 100 includes a substrate 1 having a quality deciding section 13 and a sample receiving section 15 provided on the substrate 1 to which a sample is supplied. The quality deciding section 13 includes a moisture absorbing material changed in color through absorption of moisture. The sample receiving section 15 has a reagent section 7 including an enzyme reacted with a test substance as a substrate. The quality deciding section 13 includes a recess 17 formed in the substrate 1, the moisture absorbing material 16 disposed in the recess 17 and a film 18 with no air permeability substantially covering the opening of the recess 17 and closely adhered to the moisture absorbing material 16. Cobalt salt is used as the moisture absorbing material 16.
摘要翻译： 提供一种能够容易地由普通用户确定其性能的生物传感器和生物传感器测量装置。 生物传感器100包括具有质量判定部13的基板1和设置在其上被供给样本的基板1上的样本接收部15。 质量判定部13包括通过吸收水分而变色的吸湿材料。 样品接收部分15具有试剂部分7，其包含与作为基质的测试物质反应的酶。 品质决定部13包括形成在基板1上的凹部17，设置在凹部17中的吸湿材料16和没有透气性的薄膜18，其基本上覆盖凹部17的开口并且紧密地附着在吸湿材料16上 钴盐用作吸湿材料16。
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公开(公告)号：US07238160B2
公开(公告)日：2007-07-03
申请号：US10512939
申请日：2004-01-16
申请人： Yuko Taniike , Mariko Miyashita , Shin Ikeda , Toshihiko Yoshioka
发明人： Yuko Taniike , Mariko Miyashita , Shin Ikeda , Toshihiko Yoshioka
IPC分类号： A61B5/00
CPC分类号： A61B5/6843 , A61B5/14532 , A61B5/150022 , A61B5/150259 , A61B5/150358 , A61B5/150412 , A61B5/150748 , A61B5/150954 , A61B5/15107 , A61B5/15117 , A61B5/15125 , A61B5/1519 , A61B5/157 , A61B5/417
摘要： The present invention relates to a biological component measurement apparatus set, in which a puncture mechanism for puncturing skin of a subject to collect a sample blood is integrated with a biosensor measurement apparatus. The puncture mechanism includes a puncture needle, and a cap which is detachably engaged with a body of the apparatus, wherein the cap has a skin contact surface which is brought into contact with the skin for puncturing. The skin contact surface having an opening through which the puncture needle moves to puncture the skin, and is shaped so as to fit a surface shape of the skin to be punctured. The set includes a plurality of different caps each corresponding to a different sample collection site so that a plurality of different sample collection sites can be selected.
摘要翻译： 生物成分测定装置技术领域本发明涉及一种生物成分测定装置，其特征在于，将生物体测定装置与被检体的皮肤刺穿用于收集血样的穿刺机构一体化。 穿刺机构包括穿刺针和与装置的主体可拆卸地接合的帽，其中，所述帽具有与皮肤接触以进行穿刺的皮肤接触表面。 皮肤接触表面具有穿刺针穿过的穿刺孔，并且被成形为适合要刺穿的皮肤的表面形状。 该集合包括多个不同的盖，每个不同的盖对应于不同的采样站点，从而可以选择多个不同的样本采集站点。
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公开(公告)号：US20050159678A1
公开(公告)日：2005-07-21
申请号：US10512939
申请日：2004-01-16
申请人： Yuko Taniike , Mariko Miyashita , Shin Ikeda , Toshihiko Yoshioka
发明人： Yuko Taniike , Mariko Miyashita , Shin Ikeda , Toshihiko Yoshioka
CPC分类号： A61B5/6843 , A61B5/14532 , A61B5/150022 , A61B5/150259 , A61B5/150358 , A61B5/150412 , A61B5/150748 , A61B5/150954 , A61B5/15107 , A61B5/15117 , A61B5/15125 , A61B5/1519 , A61B5/157 , A61B5/417
摘要： The present invention relates to a biological component measurement apparatus set, in which a puncture mechanism for puncturing skin of a subject to collect a sample blood is integrated with a biosensor measurement apparatus, wherein the puncture mechanism comprises at least: a puncture needle; and a cap which is detachably engaged with a body of the apparatus, wherein the cap has a skin contact surface which is brought into contact with the skin for puncturing, the skin contact surface having an opening through which the puncture needle moves to puncture the skin, and being shaped so as to fit a surface shape of the skin to be punctured, and the set comprises a plurality of different such caps each corresponding to a different sample collection site so that a plurality of different sample collection sites can be selected.
摘要翻译： 生物成分测定装置技术领域本发明涉及一种生物体成分测定装置，其特征在于，将生物体成分测定装置与生物传感器测定装置一体化，其中，穿刺机构至少包括：穿刺针， 以及与所述装置的主体可拆卸地接合的帽，其中所述帽具有与皮肤接触以刺穿的皮肤接触表面，所述皮肤接触表面具有穿刺针穿过的穿孔刺穿皮肤 并且被成形为适合要刺穿的皮肤的表面形状，并且该组包括多个不同的这样的帽，每个对应于不同的样本收集位置，使得可以选择多个不同的样本收集位置。
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公开(公告)号：US07252804B2
公开(公告)日：2007-08-07
申请号：US10472209
申请日：2003-03-19
IPC分类号： B01L9/00
CPC分类号： A61B5/1486 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B5/157 , A61B2562/0295
摘要： An adaptor for body fluid measurement of the present invention includes a puncture instrument holding section for detachably carrying a puncture instrument for protruding a puncture needle and a measuring instrument holding section for detachably carrying a measuring instrument for analyzing body fluid with a biosensor, the biosensor being attached to the measuring instrument and having a body fluid supply part to which body fluid is supplied. With use of the adaptor, the body fluid can be measured easily and speedily with the puncture instrument and the measuring instrument attached thereto, which are independent from each other. The present invention further provides a measuring instrument including a puncture instrument holding section.
摘要翻译： 本发明的体液测定用适配器包括：可拆卸地携带用于使穿刺针突出的穿刺器具的穿刺器械保持部，以及用于可拆卸地携带用生物传感器分析体液的测量仪器的测量仪器保持部，所述生物传感器 附接到测量仪器并具有供给体液的体液供给部。 通过使用适配器，可以容易且快速地测量体液，其中穿刺器械和附接到其上的测量仪器彼此独立。 本发明还提供一种包括穿刺器械保持部的测量仪器。
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公开(公告)号：US20060188395A1
公开(公告)日：2006-08-24
申请号：US10550150
申请日：2005-02-02
IPC分类号： G01N31/22
CPC分类号： C12Q1/001 , B01L3/502715 , B01L3/502746 , B01L2200/143 , B01L2300/0645 , B01L2300/0825 , B01L2300/0887 , B01L2300/105 , B01L2400/0406 , G01N31/22
摘要： A biosensor and a biosensor measuring apparatus whose performance can be easily determined by an ordinary user are provided. A biosensor 100 includes a substrate 1 having a quality deciding section 13 and a sample receiving section 15 provided on the substrate 1 to which a sample is supplied. The quality deciding section 13 includes a moisture absorbing material changed in color through absorption of moisture. The sample receiving section 15 has a reagent section 7 including an enzyme reacted with a test substance as a substrate. The quality deciding section 13 includes a recess 17 formed in the substrate 1, the moisture absorbing material 16 disposed in the recess 17 and a film 18 with no air permeability substantially covering the opening of the recess 17 and closely adhered to the moisture absorbing material 16. Cobalt salt is used as the moisture absorbing material 16.
摘要翻译： 提供一种能够容易地由普通用户确定其性能的生物传感器和生物传感器测量装置。 生物传感器100包括具有质量判定部13的基板1和设置在其上被供给样本的基板1上的样本接收部15。 质量判定部13包括通过吸收水分而变色的吸湿材料。 样品接收部分15具有试剂部分7，其包含与作为基质的测试物质反应的酶。 品质决定部13包括形成在基板1上的凹部17，设置在凹部17中的吸湿材料16和没有透气性的薄膜18，其基本上覆盖凹部17的开口并且紧密地附着在吸湿材料16上 。 钴盐用作吸湿材料16。
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8.发明申请公开(公告)号：US20050176133A1
公开(公告)日：2005-08-11
申请号：US10516751
申请日：2004-02-18
IPC分类号： C12M1/34 , G01N27/327 , G01N33/487 , G01N33/86
CPC分类号： G01N27/3274
摘要： There are provided a measuring device for a biosensor, capable of performing a simple, accurate and short-time measurement of a specific substance in a sample without being affected by physical properties of a sample, and a measuring method. In the measuring device for a biosensor in accordance with the present invention, a biosensor is used which includes: a sample supply port; an electrode system having a measurement electrode and a counter electrode; and a portion where a sample can be irradiated with light in at least part of a sample supply pathway, to detect electrical and optical variations in the sample and determine a physical factor of the sample, so that a measurement value can be corrected.
摘要翻译： 提供了一种用于生物传感器的测量装置，其能够对样品中的特定物质进行简单，准确和短时间的测量而不受样品的物理性质的影响，以及测量方法。 在根据本发明的生物传感器的测量装置中，使用生物传感器，其包括：样品供给口; 具有测量电极和对电极的电极系统; 以及可以在样品供给路径的至少一部分中用光照射样品的部分，以检测样品中的电和光学变化并确定样品的物理因子，从而可以校正测量值。
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公开(公告)号：US06969450B2
公开(公告)日：2005-11-29
申请号：US10616305
申请日：2003-07-10
IPC分类号： A61B5/00 , G01N27/30 , G01N33/487 , C12M1/00
CPC分类号： G01N33/4875 , A61B5/1486 , A61B2562/0295
摘要： In biosensor system 1, biosensor 2 is mounted in measuring apparatus 3 for quantifying or detecting existence of a targeted substrate in a sample solution. Mounting end portion 20 of biosensor 2 to be mounted in measuring apparatus 3 has an extension of one base plate in the length direction, and further extensions of the other base plate in the width direction. Sensor mounting portion 30 of measuring apparatus 3 has a shape matching up with the shape of mounting end portion 20. Thereby wrong insertion of biosensor 2 in measuring apparatus 3 can be prevented.Further, varying shapes of plural biosensors 5 and 6 to have a common part and a non-common part, such biosensors can be handily measured by one measuring apparatus 7.
摘要翻译： 在生物传感器系统1中，将生物传感器2安装在用于定量或检测样品溶液中目标基板的存在的测量装置3中。 安装在测量装置3中的生物传感器2的安装端部20在长度方向上具有一个基板的延伸部，另一个底板在宽度方向上延伸。 测量装置3的传感器安装部30具有与安装端部20的形状相匹配的形状。 从而可以防止生物传感器2在测量装置3中错误插入。 此外，多个生物传感器5和6的不同形状具有公共部分和非共同部分，可以通过一个测量装置7轻松测量这样的生物传感器。
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公开(公告)号：US07323098B2
公开(公告)日：2008-01-29
申请号：US10653257
申请日：2003-09-03
IPC分类号： G01N27/327
CPC分类号： C12Q1/004 , G01N27/3272
摘要： A biosensor capable of measuring the concentration of one or more specific substances in one or more sample solutions almost simultaneously is provided. The biosensor comprises a plurality of sensor units, and each of the sensor units comprises an electrode system including a working electrode and a counter electrode on an insulating base plate and a reagent system including an oxidoreductase and an electron mediator. The biosensor is so configured that sample solutions supplied to the respective sensor units reach the respective reagent systems at different times. Specifically, each of the sensor units has a controlling system between a sample supply inlet and the reagent system, and the controlling system controls the time it takes for the sample solution to reach the reagent system from the sample supply inlet.
摘要翻译： 提供能够几乎同时测量一种或多种样品溶液中的一种或多种特定物质的浓度的生物传感器。 生物传感器包括多个传感器单元，并且每个传感器单元包括在绝缘基板上包括工作电极和对电极的电极系统和包括氧化还原酶和电子介体的试剂系统。 生物传感器被配置成使得提供给各个传感器单元的样品溶液在不同时间到达相应的试剂系统。 具体地，每个传感器单元具有在供样入口和试剂系统之间的控制系统，控制系统控制样品溶液从样品供应入口到达试剂系统所花费的时间。
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