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公开(公告)号：US5244789A
公开(公告)日：1993-09-14
申请号：US756712
申请日：1991-09-09
IPC分类号： C12Q1/44
CPC分类号： C12Q1/44 , G01N2333/918 , G01N2405/04
摘要： The present invention provides a process for the determination of phospholipase A in body fluids, wherein the body fluid is incubated with a mixture containing a substrate having a fatty acid residue for the phospholipase and at least two emulsifiers of different chemical classes, namely, at least one neutral emulsifier and a bile acid salt, and the amount of the free fatty acids formed by the cleavage of the substrate is determined in known manner.
摘要翻译： 本发明提供了一种用于测定体液中磷脂酶A的方法，其中将体液与含有磷脂酶的脂肪酸残基的底物和至少两种不同化学等级的乳化剂，即至少 一种中性乳化剂和胆汁酸盐，并且以已知方式测定通过基底裂解形成的游离脂肪酸的量。
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公开(公告)号：US5204242A
公开(公告)日：1993-04-20
申请号：US761335
申请日：1991-09-17
IPC分类号： C07C37/00 , C07C39/24 , C07C39/27 , C07C43/178 , C07C59/52 , C07C59/56 , C07C69/732 , C07C205/56 , C07C215/48 , C07C215/66 , C07C235/34 , C07C309/24 , C07C309/68 , C07C311/13 , C07C311/27 , G01N31/22 , G03C7/34
CPC分类号： C07C235/34 , C07C205/56 , C07C309/24 , C07C311/27 , C07C39/27 , C07C59/52 , C07C59/56 , G03C7/346
摘要： The present invention provides a colorimetric process for the detection of an oxidative coupling reaction in which a coupling component is reacted with a developer component in the presence of an oxidation agent to give a colored material, wherein, as coupling component, there is used a compound of the general formula: ##STR1## in which X is a bromine or chlorine atom, n is 1, 2 or 3, Y is COOR, CONRR', SO.sub.3 R, SO.sub.2 NRR', OR, NRR' or NRR'R".sym. and R, R' and R", independently of one another, are hydrogen atoms or C.sub.1 -C.sub.3 -alkyl radicals.The present invention also provides a reagent which contains the above compound, as well as new substituted phenols and a process for the preparation thereof.
摘要翻译： 本发明提供了一种用于检测氧化偶联反应的比色方法，其中偶联组分在氧化剂存在下与显影剂组分反应，得到着色材料，其中作为偶联组分，使用化合物 其中X是溴或氯原子，其中n是1,2或3，Y是COOR，CONRR'，SO3R，SO2NRR'，OR，NRR'或NRR'R “（+）”和“R”，“R”和“R”彼此独立地是氢原子或C1-C3-烷基。 本发明还提供了含有上述化合物的试剂，以及新的取代酚类及其制备方法。
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公开(公告)号：US6057120A
公开(公告)日：2000-05-02
申请号：US934784
申请日：1997-09-22
申请人： Dieter Heindl , Rupert Herrmann , Joachim Hones , Hans-Peter Josel , Martina Junius-Comer , Hartmut Merdes , Axel Schmidt , Ernst Selbertinger
发明人： Dieter Heindl , Rupert Herrmann , Joachim Hones , Hans-Peter Josel , Martina Junius-Comer , Hartmut Merdes , Axel Schmidt , Ernst Selbertinger
IPC分类号： C07D241/38 , C07D241/46 , C07D401/14 , C07D471/04 , C07D487/04 , C07D491/048 , C07D495/04 , C12Q1/26 , G01N31/22 , G01N33/52 , C12Q1/00 , G01N33/53
CPC分类号： C07D241/38 , C07D401/14 , C12Q1/26 , G01N31/22 , G01N33/52 , Y10S435/968
摘要： The invention concerns the use of redox-active compounds for the production of detection reagents for a method for the determination of an analyte as well as reagent kits that contain these redox-active compounds. In addition new redox-active compounds are disclosed.
摘要翻译： 本发明涉及氧化还原活性化合物用于生产用于测定分析物的方法的检测试剂以及含有这些氧化还原活性化合物的试剂盒的用途。 此外，还公开了新的氧化还原活性化合物。
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公开(公告)号：US5854073A
公开(公告)日：1998-12-29
申请号：US822950
申请日：1997-03-21
CPC分类号： G01N33/728 , G01N33/96 , Y10T428/31957 , Y10T436/10 , Y10T436/103332 , Y10T436/106664 , Y10T436/146666 , Y10T436/2525
摘要： The invention concerns a stable control serum or calibration serum containing bilirubin to analytically examine the methodical accuracy of individual parameters in human sera or patients. The control serum or calibration serum according to the invention is used to stabilize bilirubin in solutions and to generally increase the stability of control sera or calibration sera.
摘要翻译： 本发明涉及一种稳定的对照血清或含有胆红素的校准血清，以分析检查人血清或患者个体参数的方法准确性。 根据本发明的对照血清或校正血清用于稳定溶液中的胆红素并且通常提高对照血清或校准血清的稳定性。
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公开(公告)号：US5654163A
公开(公告)日：1997-08-05
申请号：US506261
申请日：1995-07-24
IPC分类号： C07H15/203 , C12Q1/40 , C07H1/00 , C12N9/26 , C12Q1/54
CPC分类号： C07H15/203 , C12Q1/40 , C12Q2334/00
摘要： The invention concerns new indophenyl-substituted maltose derivatives, their use for the determination of the enzymatic activity of .alpha.-amylase and reagents for the determination of .alpha.-amylase which contain the new indophenyl-substituted maltose derivatives as the enzyme substrate.
摘要翻译： 本发明涉及新的吲哚基取代的麦芽糖衍生物，它们用于测定α-淀粉酶的酶活性和用于测定含有新的取代的取代的取代的麦芽糖衍生物作为酶底物的α-淀粉酶的试剂。
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6.发明授权Method for increasing the enzymatic reactivity of .beta.-galactosidase by addition of a cyanate, thiocyanate, azide, or thiosulfate compound 失效通过加入氰酸酯，硫氰酸酯，亚胺或硫代脂肪酸酯化合物来增加（BETA） - 乳糖苷酶的酶促反应活性的方法
公开(公告)号：US5194382A
公开(公告)日：1993-03-16
申请号：US609242
申请日：1990-11-05
CPC分类号： C12Q1/54
摘要： In order to increase the enzymatic reactivity of .beta.-galactosidase, an azide, thiocyanate, cyanate and/or thiosulphate is added to the reaction mixture.
摘要翻译： 为了增加β-半乳糖苷酶的酶反应性，向反应混合物中加入叠氮化物，硫氰酸酯，氰酸酯和/或硫代硫酸盐。
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