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21 条记录 (耗时 0.049 秒)

    Optical Raman system
    3.
    发明授权
    Optical Raman system 有权

    公开(公告)号：US11287383B2

    公开(公告)日：2022-03-29

    申请号：US16333192

    申请日：2017-09-13

    申请人： UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

    发明人： Kishan Dholakia ,  Mingzhou Chen

    IPC分类号： G01N21/65 ,  G01J3/02 ,  G01J3/44

    摘要： A Raman system for use in performing Raman spectroscopy on a sample, comprises an optical source, a spectrometer, and an optical system for coupling light from the optical source to a sample and for coupling light from the sample to the spectrometer and a further spectrometer. A Raman system for use in performing Raman spectroscopy on a sample, comprises an optical source, a spectrometer and an optical system for coupling light from the optical source and a further optical source to a sample and for coupling light from the sample to the spectrometer. The optical system may be configured for coupling light from the optical source and the further optical source to the sample and for coupling light from the sample to the spectrometer and the further spectrometer. The Raman system may be portable and/or may be configured to be transported and/or carried and/or may be handheld.

    Imaging of a sample through a scattering medium
    4.
    发明授权
    Imaging of a sample through a scattering medium 有权

    公开(公告)号：US11204319B2

    公开(公告)日：2021-12-21

    申请号：US16649563

    申请日：2018-09-20

    申请人： University Court of the University of St Andrews, College Gate

    发明人： Kishan Dholakia

    IPC分类号： G01N21/47 ,  G01N21/17 ,  G01N21/64

    摘要： A method and system are disclosed for use in imaging a sample. The method comprises illuminating a sample through a scattering medium, or illuminating a sub-surface region of the sample through a scattering surface region of the sample, with a plurality of spatial patterns of incident electromagnetic radiation, wherein each spatial pattern of incident electromagnetic radiation interacts with the sample, or the sub-surface region of the sample, to generate electromagnetic radiation in the sample or the sub-surface region of the sample. The method comprises measuring, for each spatial pattern of incident electromagnetic radiation, a corresponding value representative of a quantity of at least a portion of the emitted electromagnetic radiation and using the plurality of spatial patterns of incident electromagnetic radiation and the plurality of corresponding measured values to determine an image of the sample, or an image of the sub-surface region of the sample, without using a spatial distribution of the emitted electromagnetic radiation.

    Spatially offset optical coherence tomography
    5.
    发明授权
    Spatially offset optical coherence tomography 有权

    公开(公告)号：US10942023B2

    公开(公告)日：2021-03-09

    申请号：US16044005

    申请日：2018-07-24

    申请人： UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

    发明人： Kishan Dholakia ,  Mingzhou Chen

    IPC分类号： G01B9/02

    摘要： An optical coherence tomography system for imaging a sample is configured so as to illuminate a region of interest of the sample with incident light from an optical source. The optical coherence tomography system is further configured so as to interfere, on an optical detector, reference light from the optical source with offset returning light emerging from the sample along an offset collection path which is spatially offset from the region of interest of the sample, thereby creating interference on the optical detector.

    Three-photon light sheet imaging
    9.
    发明授权
    Three-photon light sheet imaging 有权

    公开(公告)号：US11762180B2

    公开(公告)日：2023-09-19

    申请号：US16622542

    申请日：2018-06-15

    申请人： UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

    发明人： Kishan Dholakia

    IPC分类号： G02B21/00 ,  G01N21/64

    CPC分类号： G02B21/0032 ,  G01N21/6458 ,  G01N21/6486 ,  G02B21/0076 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/06113 ,  G01N2201/08 ,  G02B2207/114

    摘要： A light sheet imaging system, such as a light sheet microscope, comprises an illumination arrangement for generating a light sheet for three-photon excitation of a fluorescent sample, and a fluorescence collection arrangement for collecting fluorescence generated in the sample as a result of three-photon excitation by the light sheet. The light sheet may be a non-diffractive, propagation-invariant light sheet. The light sheet may be formed from and/or comprise a Bessel beam. A method of light sheet imaging comprises using a light sheet for three-photon excitation of a fluorescent sample, and collecting fluorescence generated in the sample as a result of three-photon excitation of the sample by the light sheet. Such a method may be used for light sheet microscopy.

    MINIMIZATION OF CROSS-TALK IN A MULTI-MODE FIBER
    10.
    发明申请
    MINIMIZATION OF CROSS-TALK IN A MULTI-MODE FIBER 审中-公开

    公开(公告)号：US20170261761A1

    公开(公告)日：2017-09-14

    申请号：US15388745

    申请日：2016-12-22

    申请人： University Court of the University of St Andrews

    发明人： Kishan Dholakia ,  Michael Mazilu ,  Anna Chiara De Luca

    IPC分类号： G02B27/58

    CPC分类号： G02B27/58 ,  G02B2207/125

    摘要： A method of minimizing cross-talk between optical modes propagating in a multi-mode optical fiber, comprises superimposing a plurality of optical wavefunctions; determining a relationship between superpositions of at least some of the optical wavefunctions and at least one measure of orthogonality of the optical modes at an output of the multi-mode optical fiber; and identifying a superposition of at least some of the optical wavefunctions that provides a desired or optimized value of the at least one measure of orthogonality using the determined relationship. The method further comprises generating, using light from a laser and at least one optical component, the identified superposition of at least some of the optical wavefunctions that provides the desired or optimized value of the at least one measure of orthogonality.