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    Electrochemical biosensor test strip
    2.
    再颁专利
    Electrochemical biosensor test strip 有权
    电化学生物传感器试片

    公开(公告)号：USRE41309E1

    公开(公告)日：2010-05-04

    申请号：US10409721

    申请日：2003-04-09

    申请人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn ,  Richard J. Bodensteiner ,  Eric R. Diebold ,  R. Dale Delk ,  David W. Burke ,  Jiaxiong Jason Ho ,  Robert Kitchel Earl ,  Brian A. Heald

    发明人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn ,  Richard J. Bodensteiner ,  Eric R. Diebold ,  R. Dale Delk ,  David W. Burke ,  Jiaxiong Jason Ho ,  Robert Kitchel Earl ,  Brian A. Heald

    IPC分类号： G01N33/48

    CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G01N33/5438 ,  Y10S435/817

    摘要： An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes from about 0.2% by weight to about 2% by weight polyethylene oxide from about 100 kilodaltons to about 900 kilodaltons mean molecular weight, which makes the dried reagent more hydrophilic and sturdier to strip processing steps, such as mechanical punching, and to mechanical manipulation by the test strip user. The roof of the capillary test chamber includes a transparent or translucent window which operates as a “fill to here” line, thereby identifying when enough test sample (a liquid sample, such as blood) has been added to the test chamber to accurately perform a test. The test strip may further include a notch located at the sample application port. The notch reduces a phenomenon called “dose hesitation”.

    摘要翻译： 一种具有四个新特征的电化学生物传感器测试条。 测试条包括针对带样品应用端口的位置的触感的缩进。 样品应用端口通向包括测试试剂的毛细管测试室。 湿试剂包括约0.2重量％至约2重量％的聚环氧乙烷约100千道尔顿至约900千道尔顿的平均分子量，这使得干燥的试剂更具亲水性并且更坚固以进行剥离加工步骤，例如机械冲压，和 由测试用户进行机械操作。 毛细管测试室的屋顶包括透明或半透明的窗口，其作为“填充到这里”线，从而识别何时将足够的测试样品（液体样品，例如血液）添加到测试室以精确地执行 测试。 测试条还可以包括位于样品应用端口处的凹口。 缺口减少了称为“剂量犹豫”的现象。

    Electrochemical biosensor test strip
    4.
    发明授权
    Electrochemical biosensor test strip 有权
    电化学生物传感器试片

    公开(公告)号：US06270637B1

    公开(公告)日：2001-08-07

    申请号：US09386210

    申请日：1999-08-31

    申请人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn ,  Richard J. Bodensteiner ,  Eric R. Diebold ,  R. Dale Delk ,  David W. Burke ,  Jiaxiong Jason Ho ,  Robert Kitchel Earl ,  Brian A. Heald

    发明人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn ,  Richard J. Bodensteiner ,  Eric R. Diebold ,  R. Dale Delk ,  David W. Burke ,  Jiaxiong Jason Ho ,  Robert Kitchel Earl ,  Brian A. Heald

    IPC分类号： G01N2726

    CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G01N33/5438 ,  Y10S435/817

    摘要： An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes from about 0.2% by weight to about 2% by weight polyethylene oxide from about 100 kilodaltons to about 900 kilodaltons mean molecular weight, which makes the dried reagent more hydrophilic and sturdier to strip processing steps, such as mechanical punching, and to mechanical manipulation by the test strip user. The roof of the capillary test chamber includes a transparent or translucent window which operates as a “fill to here” line, thereby identifying when enough test sample (a liquid sample, such as blood) has been added to the test chamber to accurately perform a test. The test strip may further include a notch located at the sample application port. The notch reduces a phenomenon called “dose hesitation”.

    摘要翻译： 一种具有四个新特征的电化学生物传感器测试条。 测试条包括针对带样品应用端口的位置的触感的缩进。 样品应用端口通向包括测试试剂的毛细管测试室。 湿试剂包括约0.2重量％至约2重量％的聚环氧乙烷约100千道尔顿至约900千道尔顿的平均分子量，这使得干燥的试剂更具亲水性并且更坚固以进行剥离加工步骤，例如机械冲压，和 由测试用户进行机械操作。 毛细管测试室的屋顶包括透明或半透明的窗口，其作为“填充到这里”线，从而识别何时将足够的测试样品（液体样品，例如血液）添加到测试室以精确地执行 测试。 测试条还可以包括位于样品应用端口处的凹口。 缺口减少了称为“剂量犹豫”的现象。

    Electrochemical biosensor test strip
    5.
    再颁专利
    Electrochemical biosensor test strip 有权

    公开(公告)号：USRE42560E1

    公开(公告)日：2011-07-19

    申请号：US10693305

    申请日：2003-10-24

    申请人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn

    发明人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn

    IPC分类号： G01N33/48

    CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G01N33/5438 ,  Y10S435/817

    摘要： An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes from about 0.2% by weight to about 2% by weight polyethylene oxide from about 100 kilodaltons to about 900 kilodaltons mean molecular weight, which makes the dried reagent more hydrophilic and sturdier to strip processing steps, such as mechanical punching, and to mechanical manipulation by the test strip user. The roof of the capillary test chamber includes a transparent or translucent window which operates as a “fill to here” line, thereby identifying when enough test sample (a liquid sample, such as blood) has been added to the test chamber to accurately perform a test. The test strip may further include a notch located at the sample application port. The notch reduces a phenomenon called “dose hesitation”.

    Electrochemical biosensor test strip
    6.
    再颁专利
    Electrochemical biosensor test strip 有权
    电化学生物传感器试片

    公开(公告)号：USRE43815E1

    公开(公告)日：2012-11-20

    申请号：US13301334

    申请日：2011-11-21

    申请人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn

    发明人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn

    IPC分类号： G01N33/48

    CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G01N33/5438 ,  Y10S435/817

    摘要： An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes from about 0.2% by weight to about 2% by weight polyethylene oxide from about 100 kilodaltons to about 900 kilodaltons mean molecular weight, which makes the dried reagent more hydrophilic and sturdier to strip processing steps, such as mechanical punching, and to mechanical manipulation by the test strip user. The roof of the capillary test chamber includes a transparent or translucent window which operates as a “fill to here” line, thereby identifying when enough test sample (a liquid sample, such as blood) has been added to the test chamber to accurately perform a test. The test strip may further include a notch located at the sample application port. The notch reduces a phenomenon called “dose hesitation”.

    摘要翻译： 一种具有四个新特征的电化学生物传感器测试条。 测试条包括针对带样品应用端口的位置的触感的缩进。 样品应用端口通向包括测试试剂的毛细管测试室。 湿试剂包括约0.2重量％至约2重量％的聚环氧乙烷约100千道尔顿至约900千道尔顿的平均分子量，这使得干燥的试剂更具亲水性并且更坚固以进行剥离加工步骤，例如机械冲压，和 由测试用户进行机械操作。 毛细管测试室的顶部包括透明或半透明的窗口，其作为填充物进行操作，从而识别何时将足够的测试样品（液体样品，例如血液）添加到测试室以准确地进行测试。 测试条还可以包括位于样品应用端口处的凹口。 缺口减少了称为剂量犹豫的现象。

    Electrochemical biosensor test strip
    7.
    再颁专利
    Electrochemical biosensor test strip 有权
    电化学生物传感器试片

    公开(公告)号：USRE42924E1

    公开(公告)日：2011-11-15

    申请号：US10692031

    申请日：2003-10-23

    申请人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn

    发明人： William F. Crismore ,  Nigel A. Surridge ,  Daniel R. McMinn

    IPC分类号： G01N33/48

    CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G01N33/5438 ,  Y10S435/817

    摘要： An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes from about 0.2% by weight to about 2% by weight polyethylene oxide from about 100 kilodaltons to about 900 kilodaltons mean molecular weight, which makes the dried reagent more hydrophilic and sturdier to strip processing steps, such as mechanical punching, and to mechanical manipulation by the test strip user. The roof of the capillary test chamber includes a transparent or translucent window which operates as a “fill to here” line, thereby identifying when enough test sample (a liquid sample, such as blood) has been added to the test chamber to accurately perform a test. The test strip may further include a notch located at the sample application port. The notch reduces a phenomenon called “dose hesitation”.

    摘要翻译： 一种具有四个新特征的电化学生物传感器测试条。 测试条包括针对带样品应用端口的位置的触感的缩进。 样品应用端口通向包括测试试剂的毛细管测试室。 湿试剂包括约0.2重量％至约2重量％的聚环氧乙烷约100千道尔顿至约900千道尔顿的平均分子量，这使得干燥的试剂更具亲水性并且更坚固以进行剥离加工步骤，例如机械冲压，和 由测试用户进行机械操作。 毛细管测试室的屋顶包括透明或半透明的窗口，其作为“填充到这里”线，从而识别何时将足够的测试样品（液体样品，例如血液）添加到测试室以精确地执行 测试。 测试条还可以包括位于样品应用端口处的凹口。 缺口减少了称为“剂量犹豫”的现象。

    Electrochemical sensor
    9.
    发明授权
    Electrochemical sensor 失效
    电化学传感器

    公开(公告)号：US5437999A

    公开(公告)日：1995-08-01

    申请号：US200174

    申请日：1994-02-22

    申请人： Eric R. Diebold ,  Richard J. Kordal ,  Nigel A. Surridge ,  Christopher D. Wilsey

    发明人： Eric R. Diebold ,  Richard J. Kordal ,  Nigel A. Surridge ,  Christopher D. Wilsey

    IPC分类号： G01N27/28 ,  C12M1/40 ,  C12Q1/00 ,  C25B11/00 ,  G01N27/26 ,  G01N27/30 ,  G01N27/327 ,  G01N27/403 ,  G01N27/416 ,  G01N33/487 ,  C12M1/34

    CPC分类号： C12Q1/001 ,  G01N27/3272 ,  Y10S435/817

    摘要： A method for fabricating high-resolution, biocompatible electrodes is disclosed, allowing production of an electrochemical sensor which is capable of precise analyte concentration determination on a very small sample size. Electrically conducting material is affixed to a first insulating substrate. A second insulating substrate is then affixed to the electrically conducting material and patterned using photolithography to define an electrode area. Alternatively, the electrically conducting material may be screen printed directly onto a standard printed circuit board substrate in the case of a counter or reference electrode. In either case, the substrate may be rigid or flexible. When the electrodes produced in accordance with the present invention are then used in an electrochemical sensor which includes a reagent, the small and highly-defined electrode areas permit highly-accurate electrochemical analyte measurements to be performed on very small sample sizes.

    摘要翻译： 公开了一种用于制造高分辨率生物相容性电极的方法，其允许生产能够在极小样品尺寸上精确分析物浓度测定的电化学传感器。 导电材料固定在第一绝缘基片上。 然后将第二绝缘基板固定到导电材料上，并使用光刻法图案化以限定电极区域。 或者，在计数器或参考电极的情况下，导电材料可以直接丝网印刷到标准印刷电路板基底上。 在任一情况下，衬底可以是刚性的或柔性的。 当根据本发明生产的电极然后用于包括试剂的电化学传感器中时，小且高度限定的电极区域允许在非常小的样品尺寸上进行高精度的电化学分析物测量。