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公开(公告)号：US4876127A
公开(公告)日：1989-10-24
申请号：US269030
申请日：1988-11-09
CPC分类号： B29C49/0005 , C08K5/5399 , B29K2077/00 , Y10T428/1352
摘要： This invention relates to a process for blow molding polyamide compositions where the molten polyamide includes an effective amount of one or more aryl phosphoryl azide compounds.
摘要翻译： 本发明涉及一种吹塑聚酰胺组合物的方法，其中熔融聚酰胺包括有效量的一种或多种芳基磷酰基叠氮化合物。
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公开(公告)号：US5403896A
公开(公告)日：1995-04-04
申请号：US938118
申请日：1992-09-01
申请人： Yash P. Khanna , Rakesh Kumar , John P. Sibilia
发明人： Yash P. Khanna , Rakesh Kumar , John P. Sibilia
摘要： New process for blowing molding polyamide compositions, employing a composition comprising a polyamide and one or more cyanate components, specifically cross-linking cyanates which form a triazine upon curing.
摘要翻译： 用于吹塑成型聚酰胺组合物的新方法，使用包含聚酰胺和一种或多种氰酸酯组分的组合物，特别是在固化时交联形成三嗪的氰酸酯。
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公开(公告)号：US5122592A
公开(公告)日：1992-06-16
申请号：US402164
申请日：1989-09-01
CPC分类号： C08J3/00 , C08F6/00 , C08J2327/18
摘要： This invention relates to a process of preparing polytetrafluoroethylene comprising one or more fractions of polyethylene having a melting point of greater than about 340.degree. C. by subjecting a polytetrafluoroethylene to a shear at elevated temperature.
摘要翻译： 本发明涉及通过使聚四氟乙烯在升高的温度下进行剪切而制备聚四氟乙烯的方法，该方法包括熔点大于约340℃的一种或多种聚乙烯部分。
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4.发明授权Matrix-matrix polyblend adhesives and method of bonding incompatible polymers 失效基质矩阵聚合胶粘剂和粘合不相容聚合物的方法
公开(公告)号：US4886689A
公开(公告)日：1989-12-12
申请号：US196819
申请日：1988-05-19
IPC分类号： B29C47/06 , B32B7/12 , C09J123/02
CPC分类号： B32B7/12 , B29C47/06 , C09J123/02 , B29C47/0023 , Y10S525/903 , Y10S525/931 , Y10T428/1352 , Y10T428/31544
摘要： A novel adhesive is described, consisting of a matrix-matrix polyblend of polymer components useful in an adhesive tie layer to bond incompatible polymer layers. The adhesives are a blend of the components making up the incompatible polymer layers themselves, or polymers substantially similar to these, and are melt processed to produce a matrix-matrix morphology with mechanical interlocking of the polymer components that is maintained upon cooling. Additives may be provided in one or both adhesive components to improve the cohesive strength of the adhesive formed by the mechanical interlocking.
摘要翻译： 描述了一种新型粘合剂，其由用于粘合不相容的聚合物层的粘合剂粘合层中的聚合物组分的基质 - 基质聚合物组成。 粘合剂是构成不相容的聚合物层本身的组分或基本上与其相似的聚合物的共混物，并且被熔融加工以产生基体 - 基体形态，其中冷凝时保持的聚合物组分具有机械互锁。 可以在一个或两个粘合剂组分中提供添加剂，以改善通过机械互锁形成的粘合剂的内聚强度。
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公开(公告)号：US11701393B2
公开(公告)日：2023-07-18
申请号：US17885784
申请日：2022-08-11
申请人： Babita Agrawal , Rakesh Kumar , Nancy Gupta
发明人： Babita Agrawal , Rakesh Kumar , Nancy Gupta
摘要： The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
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公开(公告)号：US11419904B2
公开(公告)日：2022-08-23
申请号：US17372614
申请日：2021-07-12
申请人： Babita Agrawal , Rakesh Kumar , Nancy Gupta
发明人： Babita Agrawal , Rakesh Kumar , Nancy Gupta
摘要： The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
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公开(公告)号：US20180000926A1
公开(公告)日：2018-01-04
申请号：US15543216
申请日：2016-01-15
申请人： Babita Agrawal , Rakesh Kumar , Shakti Singh
发明人： Babita Agrawal , Rakesh Kumar , Shakti Singh
CPC分类号： A61K39/12 , A61K39/0011 , A61K2039/5154 , A61K2039/5256 , A61K2039/53 , A61K2039/54 , A61K2039/55561 , A61K2039/57 , A61K2039/572 , A61K2039/575 , C12N7/00 , C12N2710/10043 , C12N2770/24234 , C12N2770/24271
摘要： The present disclosure provides methods for inducing an immune response to hepatitis C virus (HCV) in an individual. The present disclosure provides methods for treating an HCV infection in an individual.
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公开(公告)号：US20160317637A1
公开(公告)日：2016-11-03
申请号：US15108744
申请日：2015-01-07
申请人： Babita Agrawal , Rakesh Kumar
发明人： Babita Agrawal , Rakesh Kumar
IPC分类号： A61K39/02 , A61K39/35 , A61K39/395 , A61K39/00
CPC分类号： A61K39/02 , A61K39/0011 , A61K39/015 , A61K39/04 , A61K39/12 , A61K39/35 , A61K39/39 , A61K39/395 , A61K2039/505 , A61K2039/521 , A61K2039/55516 , A61K2039/55572 , A61K2039/58 , C12N2710/10343 , C12N2730/10134 , C12N2760/16134 , C12N2760/16234 , C12N2770/24234 , Y02A50/41 , Y02A50/412 , Y02A50/423 , Y02A50/487 , Y02A50/489 , Y02A50/491
摘要： The present disclosure provides immunomodulatory compositions comprising heat-killed Caulobacter crescentus (HKCC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising HKCC to the individual.
摘要翻译： 本公开提供了包含热灭活的新月牙菌（HKCC）的免疫调节组合物。 本公开的免疫调节组合物可用于调节个体的免疫应答。 本公开因此提供调节个体的免疫应答的方法，包括向个体施用包含HKC的免疫调节组合物。
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9.发明授权Method and apparatus for generating three-dimensional pose using multi-modal sensor fusion 有权使用多模式传感器融合产生三维姿势的方法和装置公开(公告)号：US09031809B1
公开(公告)日：2015-05-12
申请号：US13182987
申请日：2011-07-14
申请人： Rakesh Kumar , Supun Samarasekera , Han-Pang Chiu , Zhiwei Zhu , Taragay Oskiper , Lu Wang , Raia Hadsell
发明人： Rakesh Kumar , Supun Samarasekera , Han-Pang Chiu , Zhiwei Zhu , Taragay Oskiper , Lu Wang , Raia Hadsell
CPC分类号： G01C21/165 , G01C21/005 , G01S1/00 , G01S5/163 , G06F3/012 , G06F3/017 , G06F3/0304 , G06K9/00671 , G06T7/246 , G06T7/277 , G06T7/285 , G06T2207/10021 , G06T2207/30244
摘要： A method and apparatus for providing three-dimensional navigation for a node comprising an inertial measurement unit for providing gyroscope, acceleration and velocity information (collectively IMU information); a ranging unit for providing distance information relative to at least one reference node; at least one visual sensor for providing images of an environment surrounding the node; a preprocessor, coupled to the inertial measurement unit, the ranging unit and the plurality of visual sensors, for generating error states for the IMU information, the distance information and the images; and an error-state predictive filter, coupled to the preprocessor, for processing the error states to produce a three-dimensional pose of the node.
摘要翻译： 一种用于为节点提供三维导航的方法和装置，包括用于提供陀螺仪，加速度和速度信息（统称IMU信息）的惯性测量单元; 测距单元，用于相对于至少一个参考节点提供距离信息; 至少一个视觉传感器，用于提供围绕该节点的环境的图像; 耦合到惯性测量单元，测距单元和多个视觉传感器的预处理器，用于产生IMU信息，距离信息和图像的误差状态; 以及耦合到所述预处理器的错误状态预测滤波器，用于处理所述错误状态以产生所述节点的三维姿态。
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10.发明授权Pharmaceutical combination of pazopanib and topotecan to treat neuroblastoma, osteosarcoma, and rhabdomyosarcoma in a human 失效帕可帕尼与托泊替康的药物联合治疗人类的神经母细胞瘤，骨肉瘤和横纹肌肉瘤公开(公告)号：US08709420B2
公开(公告)日：2014-04-29
申请号：US13990515
申请日：2011-11-23
申请人： Rakesh Kumar , Sylvain Baruchel
发明人： Rakesh Kumar , Sylvain Baruchel
IPC分类号： A61K45/06
CPC分类号： A61K31/506 , A61K31/4375 , A61K31/4745 , A61K2300/00
摘要： The present invention relates to methods of treating neuroblastoma, osteosarcoma, and rhabdomyosarcoma in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a neuroblastoma treatment method that includes administering 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, or a pharmaceutically acceptable salt thereof, and (S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione, or a pharmaceutically acceptable salt thereof, to a human in need thereof.
摘要翻译： 本发明涉及治疗人类的神经母细胞瘤，骨肉瘤和横纹肌肉瘤的方法以及用于这种治疗的药物组合。 特别地，该方法涉及神经母细胞瘤治疗方法，其包括施用5 - [[4 - [（2,3-二甲基-2H-吲唑-6-基）甲基氨基] -2-嘧啶基]氨基] -2-甲基苯磺酰胺， 或其药学上可接受的盐，和（S）-10 - [（二甲基氨基）甲基] -4-乙基-4,9-二羟基-1H-吡喃并[3'，4'：6,7]吲哚并[1,2 b]喹啉-3,14-（4H，12H） - 二酮或其药学上可接受的盐。
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