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    Process for preparing major histocompatibility antigen class II protein and materials in which the same is bound
    2.
    发明授权
    Process for preparing major histocompatibility antigen class II protein and materials in which the same is bound 失效
    制备主要组织相容性抗原II类蛋白质的方法及其相同结合的材料

    公开(公告)号：US06630315B1

    公开(公告)日：2003-10-07

    申请号：US08929157

    申请日：1997-09-11

    申请人： Keishi Miwa ,  Mayumi Fukuyama ,  Takehiko Uchiyama

    发明人： Keishi Miwa ,  Mayumi Fukuyama ,  Takehiko Uchiyama

    IPC分类号： B01D1508

    CPC分类号： C07K14/70539 ,  C07K14/47

    摘要： This invention provides a process for producing major histocompatibility antigen class II protein (hereinafter referred to as “MHC class II” for short) which occurs on the surfaces of antigen-presenting cells and the like, and MHC class II-bound materials in which MHC class II, &agr; and/or &bgr; subunit of MHC class II, or a part thereof is bound to a carrier such as beads, fibers and hollow fibers via covalent bond, as well as a module for removing superantigen using the same. This invention also provides a method for detecting or quantifying superantigens using MHC class II or a part thereof having an affinity to the superantigens, as well as an assay kit therefor.

    摘要翻译： 本发明提供了在抗原呈递细胞等表面发生的主要组织相容性抗原II类蛋白（以下简称为“MHC类II”）和MHC II类结合材料的制备方法，其中MHC II类MHC II类的α和/或β亚基，或其一部分通过共价键与载体如珠，纤维和中空纤维结合，以及使用其的去除超抗原的模块。 本发明还提供了使用对超级抗原具有亲和力的MHC II类或其一部分以及其测定试剂盒来检测或定量超级抗原的方法。

    Bonded substrate, liquid discharge head, and liquid discharge apparatus
    3.
    发明授权
    Bonded substrate, liquid discharge head, and liquid discharge apparatus 有权

    公开(公告)号：US10744768B2

    公开(公告)日：2020-08-18

    申请号：US16262247

    申请日：2019-01-30

    申请人： Keishi Miwa

    发明人： Keishi Miwa

    IPC分类号： B41J2/14 ,  B41J2/16

    摘要： A bonded substrate includes a first substrate, a second substrate bonded to the first substrate with adhesive applied to the second substrate, and a checking structure disposed on the first substrate and facing the second substrate. The checking structure includes a bonding surface portion to be adhered to the second substrate with the adhesive and an insufficiency detection surface to detect insufficient adhesion, a height of the insufficiency detection surface being lower than a height of the bonding surface portion. The adhesive does not contact the insufficiency detection surface when an adhesion state of the bonding surface portion to the second substrate with the adhesive is insufficient, and the adhesive contacts the insufficiency detection surface when the adhesion state of the bonding surface portion to the second substrate with the adhesive is sufficient.

    PIEZOELECTRIC ACTUATOR, LIQUID DISCHARGE HEAD, AND LIQUID DISCHARGE APPARATUS
    4.
    发明公开
    PIEZOELECTRIC ACTUATOR, LIQUID DISCHARGE HEAD, AND LIQUID DISCHARGE APPARATUS 审中-公开

    公开(公告)号：US20240316928A1

    公开(公告)日：2024-09-26

    申请号：US18605948

    申请日：2024-03-15

    申请人： Keishi Miwa

    发明人： Keishi Miwa

    IPC分类号： B41J2/14 ,  H10N30/20 ,  H10N30/87

    CPC分类号： B41J2/14233 ,  H10N30/2047 ,  H10N30/87 ,  H10N30/877 ,  B41J2002/14258

    摘要： A piezoelectric actuator includes: a substrate having an opening; a diaphragm: having a first face on one face of the substrate; and facing the opening; and a piezoelectric element including: a lower electrode; a piezoelectric body; and an upper electrode, and the lower electrode, the piezoelectric body, and the upper electrode being sequentially laminated on a second face opposite to the first face of the diaphragm in a lamination direction, wherein the lower electrode includes: a first lower electrode extending in a first direction; and multiple second lower electrodes: each extending in the first direction; on each of both sides of the first lower electrode in a second direction orthogonal to the first direction; and separated from the first lower electrode in the second direction, and the piezoelectric body is interior of both ends of the opening in the second direction.

    Electromechanical transducer, liquid droplet discharge head, and image forming apparatus
    6.
    发明授权
    Electromechanical transducer, liquid droplet discharge head, and image forming apparatus 有权
    机电换能器，液滴喷射头和图像形成装置

    公开(公告)号：US09321263B2

    公开(公告)日：2016-04-26

    申请号：US14748517

    申请日：2015-06-24

    申请人： Toshiaki Masuda ,  Keishi Miwa

    发明人： Toshiaki Masuda ,  Keishi Miwa

    IPC分类号： B41J2/045 ,  B41J2/14 ,  H01L41/047

    CPC分类号： B41J2/14201 ,  B41J2/14233 ,  B41J2/161 ,  B41J2/1628 ,  B41J2/1631 ,  B41J2/1642 ,  B41J2/1645 ,  H01L41/047 ,  H01L41/29 ,  H01L41/332

    摘要： An electromechanical transducer includes a substrate; a diaphragm formed on the substrate; and a piezoelectric element that includes a lower electrode; a piezoelectric member; and an upper electrode, in which a lower electrode film to form the lower electrode, a piezoelectric film to form the piezoelectric member, and an upper electrode film to form the upper electrode are laminated in layers on the diaphragm formed on the substrate. The piezoelectric element is formed such that the lower electrode film, the piezoelectric member film, and the upper electrode film are patterned to form the lower electrode, the piezoelectric member, and the upper electrode, each of which has a desired pattern; and corners of the lower electrode are rounded.

    摘要翻译： 机电换能器包括基板; 形成在所述基板上的隔膜; 以及包括下电极的压电元件; 压电元件; 并且在形成在基板上的隔膜上层叠有形成下电极的下电极膜，形成压电元件的压电膜和形成上电极的上电极膜的上电极。 压电元件形成为使得下电极膜，压电元件膜和上电极膜被图案化以形成每个都具有期望图案的下电极，压电元件和上电极; 并且下电极的角部是圆形的。

    Method for Rapidly and Conveniently Detecting Target Substances and Enzyme Immunological Kit Therefor
    7.
    发明申请
    Method for Rapidly and Conveniently Detecting Target Substances and Enzyme Immunological Kit Therefor 审中-公开
    快速方便地检测目标物质的方法和酶免疫试剂盒

    公开(公告)号：US20080038757A1

    公开(公告)日：2008-02-14

    申请号：US11596385

    申请日：2005-05-13

    申请人： Naoko Shibayama ,  Keishi Miwa

    发明人： Naoko Shibayama ,  Keishi Miwa

    IPC分类号： G01N33/535 ,  C12M1/40

    CPC分类号： G01N33/54393 ,  G01N33/543 ,  G01N33/6869 ,  G01N2333/5412

    摘要： A measurement kit capable of rapidly and conveniently detecting one type or a plurality of types of target substance(s) simultaneously in a sample and a measurement method therefor are provided. Furthermore, with the kit or the measurement method, disease with which a target substance is associated is diagnosed. The enzyme immunological kit comprises: a support upon the surface of which a substance that recognizes a target substance is immobilized; an enzyme-labeled antibody against the target substance; and a substrate whose reaction product is water-insoluble after the enzyme-labeled antibody is caused to undergo color development; with which the target substance in a sample is detected based on color development on the support surface. Alternatively, the measurement method comprises 2 reaction steps: the incubation step and the color development step, by which a target substance in a sample is detected or the concentration of the target substance in the sample is measured through visual determination of color developed on the support surface after the color development reaction.

    摘要翻译： 本发明提供能够快速方便地检测样品中的一种或多种目标物质同时检测的测定试剂及其测定方法。 此外，通过试剂盒或测量方法，诊断出与其相关的目标物质的疾病。 酶免疫试剂盒包括：其表面上的支持物，其识别目标物质的物质被固定; 针对靶物质的酶标记抗体; 以及使酶标记的抗体发生显色后，其反应产物为水不溶性的底物; 基于载体表面上的颜色显现来检测样品中的目标物质。 或者，测量方法包括2个反应步骤：孵育步骤和显色步骤，通过该步骤检测样品中的目标物质或样品中目标物质的浓度，通过目视确定在载体上显影的颜色 表面后发色反应。

    ELECTROMECHANICAL TRANSDUCER, LIQUID DROPLET DISCHARGE HEAD, AND IMAGE FORMING APPARATUS
    9.
    发明申请
    ELECTROMECHANICAL TRANSDUCER, LIQUID DROPLET DISCHARGE HEAD, AND IMAGE FORMING APPARATUS 有权
    机电传感器，液体放电头和图像形成装置

    公开(公告)号：US20160001556A1

    公开(公告)日：2016-01-07

    申请号：US14748517

    申请日：2015-06-24

    申请人： Toshiaki Masuda ,  Keishi Miwa

    发明人： Toshiaki Masuda ,  Keishi Miwa

    IPC分类号： B41J2/14 ,  H01L41/047

    CPC分类号： B41J2/14201 ,  B41J2/14233 ,  B41J2/161 ,  B41J2/1628 ,  B41J2/1631 ,  B41J2/1642 ,  B41J2/1645 ,  H01L41/047 ,  H01L41/29 ,  H01L41/332

    摘要： An electromechanical transducer includes a substrate; a diaphragm formed on the substrate; and a piezoelectric element that includes a lower electrode; a piezoelectric member; and an upper electrode, in which a lower electrode film to form the lower electrode, a piezoelectric film to form the piezoelectric member, and an upper electrode film to form the upper electrode are laminated in layers on the diaphragm formed on the substrate. The piezoelectric element is formed such that the lower electrode film, the piezoelectric member film, and the upper electrode film are patterned to form the lower electrode, the piezoelectric member, and the upper electrode, each of which has a desired pattern; and corners of the lower electrode are rounded.

    摘要翻译： 机电换能器包括基板; 形成在所述基板上的隔膜; 以及包括下电极的压电元件; 压电元件; 并且在形成在基板上的隔膜上层叠有形成下电极的下电极膜，形成压电元件的压电膜和形成上电极的上电极膜的上电极。 压电元件形成为使得下电极膜，压电元件膜和上电极膜被图案化以形成每个都具有期望图案的下电极，压电元件和上电极; 并且下电极的角部是圆形的。