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公开(公告)号：US07613502B2
公开(公告)日：2009-11-03
申请号：US11205184
申请日：2005-08-17
IPC分类号： A61B5/00
CPC分类号： A61B5/14553 , A61B5/0042 , A61B5/064 , A61B5/6814 , A61B5/7425 , A61B5/743 , A61B34/20 , A61B2034/2051 , A61B2034/2055 , A61B2034/2063
摘要： In a probe positioning technology, an optical bioinstrumentation includes a region selecting unit that is used to delineate a region of interest in an anatomical image of a subject, a computing unit that determines a recommended probe position according to the region of interest, a probe position sensor that detects a current probe position, a computing unit that calculates the distance between the recommended probe position and the current probe position, and an alarm device that generates an alarm sound or the like when the distance falls within a predetermined range. Moreover, the optical bioinstrumentation for living body further includes a memory unit in which the probe position is saved together with measurement data.
摘要翻译： 在探针定位技术中，光学生物仪器包括区域选择单元，其用于描绘对象的解剖图像中的感兴趣区域，计算单元，其根据感兴趣的区域确定推荐的探针位置，探针位置 检测当前探头位置的传感器，计算推荐探测位置与当前探测位置之间的距离的计算单元，以及当距离在预定范围内时产生报警声等的报警装置。 此外，生物体的光学生物仪器还包括存储单元，其中探测位置与测量数据一起被保存。
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公开(公告)号：US20060100526A1
公开(公告)日：2006-05-11
申请号：US11205184
申请日：2005-08-17
IPC分类号： A61B6/00
CPC分类号： A61B5/14553 , A61B5/0042 , A61B5/064 , A61B5/6814 , A61B5/7425 , A61B5/743 , A61B34/20 , A61B2034/2051 , A61B2034/2055 , A61B2034/2063
摘要： In a probe positioning technology, an optical bioinstrumentation includes a region selecting unit that is used to delineate a region of interest in an anatomical image of a subject, a computing unit that determines a recommended probe position according to the region of interest, a probe position sensor that detects a current probe position, a computing unit that calculates the distance between the recommended probe position and the current probe position, and an alarm device that generates an alarm sound or the like when the distance falls within a predetermined range. Moreover, the optical bioinstrumentation for living body further includes a memory unit in which the probe position is saved together with measurement data.
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3.发明授权公开(公告)号：US07974671B2
公开(公告)日：2011-07-05
申请号：US10572357
申请日：2004-09-03
申请人： Michiyuki Fujiwara , Tsuneaki Kawaguchi , Fumio Kawaguchi , Shingo Kawasaki , Atsushi Maki , Yukiko Hirabayashi , Yukari Yamamoto , Masashi Kiguchi , Hiroki Sato , Tsuyoshi Yamamoto , Takushige Katsura , Hideo Kawaguchi
发明人： Michiyuki Fujiwara , Tsuneaki Kawaguchi , Fumio Kawaguchi , Shingo Kawasaki , Atsushi Maki , Yukiko Hirabayashi , Yukari Yamamoto , Masashi Kiguchi , Hiroki Sato , Tsuyoshi Yamamoto , Takushige Katsura , Hideo Kawaguchi
IPC分类号： A61B5/00
CPC分类号： A61B5/14553 , A61B5/0042 , A61B5/0059 , A61B5/0261 , A61B5/0476 , A61B5/0478 , A61B5/0482 , A61B5/0484 , A61B5/0488 , A61B5/11 , A61B5/6822 , A61B5/742 , A61B2562/0209 , A61B2562/0233 , A61B2562/046
摘要： A living body information signal processing system (100) combining organically a living body optical measurement apparatus and a brain wave measurement apparatus, the living body optical measurement apparatus (300) in which inspection light of from visible to near infrared is irradiated on a head portion of a subject (140) and the penetration light is received and which measures an optical characteristic variation induced by a brain activity inside the head portion as a living body optical signal and the brain wave measurement apparatus (400) which measures an electrical characteristic variation induced by a brain activity inside the head portion of the subject as a brain wave signal, is provided with a probe device (50) used for both apparatus; and a living body information signal processing and displaying device (200) which displays the living body optical signal corresponding to respective measurement positions from the living body optical measurement apparatus and the brain wave signal corresponding to respective measurement positions from the brain wave measurement apparatus on a common display device while correlating the respective measurement positions each other, thereby, with the system comprehensive observation of both data can be achieved.
摘要翻译： 一种生物体信息信号处理系统（100），其组织有机地生物体光学测量装置和脑电波测定装置，所述生物体光学测量装置（300）将从所述可见光到近红外线的检查光照射在头部 并且测量由头部内部的脑活动引起的作为生物体光信号的光学特性变化和测量电特性变化的脑波测量装置（400）的穿透光， 通过作为脑波信号的被检体头部内的脑活动，设置有用于两个装置的探针装置（50）; 以及生物体信息信号处理和显示装置（200），其从来自所述生物体光学测量装置的对应于各测量位置的生物体光信号和对应于来自所述脑波测量装置的各测量位置的脑波信号 共同显示装置，同时将各个测量位置相互关联，从而可以实现对两个数据的系统综合观察。
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公开(公告)号：US08003907B2
公开(公告)日：2011-08-23
申请号：US12607209
申请日：2009-10-28
申请人： Takeshi Hoshino , Akiko Obata (nee Nakajima) , Atsushi Maki , Yukari Yamamoto , Manabu Yanagimoto , Yujin Tsukada , Chizuko Sasanabe
发明人： Takeshi Hoshino , Akiko Obata (nee Nakajima) , Atsushi Maki , Yukari Yamamoto , Manabu Yanagimoto , Yujin Tsukada , Chizuko Sasanabe
IPC分类号： H01H13/83
CPC分类号： B66B3/00
摘要： To reduce the number of erroneous operations, on an operation apparatus conducting mutually different operations such as opening and closing operations, a concretized human pictogram indicating mutually different state changes such as state changes represented by use of a face with opened eyes and a face with closed eyes associated with operation signals assigned to a pair of operation switches and a pictogram in which the human pictogram is combined with an operation pictogram representing a state in which a door concretizing an operation target to operate in response to an operation signal is opened or is being completely closed are respectively attached to the operation switches disposed adjacent to each other.
摘要翻译： 为了减少错误操作的数量，在进行诸如打开和关闭操作的相互不同的操作的操作装置上，指示表示相互不同的状态变化的具体化的人象形图，例如使用打开的眼睛的脸部和用闭合的面部表示的状态变化 与分配给一对操作开关的操作信号相关联的眼睛和其中将人体象形图与表示将操作对象混合以操作的门对应于操作信号的状态的操作象形图组合的象形图被打开或正在被 完全闭合分别附接到彼此相邻布置的操作开关。
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公开(公告)号：US20070055136A1
公开(公告)日：2007-03-08
申请号：US11471708
申请日：2006-06-21
申请人： Yukari Yamamoto , Atsushi Maki
发明人： Yukari Yamamoto , Atsushi Maki
IPC分类号： A61B5/05
CPC分类号： G01R33/48 , A61B5/055 , A61B5/417 , A61B5/4509
摘要： A means to predict bone density reduction before it actually begins will be provided. This invention provides a method to detect abnormalities in the bone marrow hemopoietic cells which precede the bone density reduction, by obtaining a nuclear magnetic resonance image containing a flat bone or an a long bone epiphysis, and evaluating the signal intensity in the red marrow area.
摘要翻译： 将提供在实际开始之前预测骨密度降低的手段。 本发明提供一种检测骨密度降低前的骨髓造血细胞异常的方法，通过获得含有平骨或长骨骨ysis的核磁共振图像，评价红髓区域的信号强度。
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公开(公告)号：US20100272337A1
公开(公告)日：2010-10-28
申请号：US12741086
申请日：2008-07-07
申请人： Toru Shirai , Yoshitaka Bito , Yukari Yamamoto , Satoshi Hirata
发明人： Toru Shirai , Yoshitaka Bito , Yukari Yamamoto , Satoshi Hirata
IPC分类号： G06K9/00
CPC分类号： G01R33/56518 , G01R33/485 , G01R33/5618
摘要： While removing signals unnecessary for measuring signals from a metabolite, data required for eddy current correction are obtained in a short period of time. Signals from an unnecessary substance which is not an object of the measurement are removed, and phase data for correcting spectral distortion caused by an eddy current are obtained by a single measurement. Two kinds of frequency-selective pulses of which intensities are adjusted so that the signals from the unnecessary substance should have the same absolute values of intensities and opposite polarities are applied with changing intensities for every phase encoding for at least one axis, and the obtained signals are arranged in a k-space. By removing aliasing of image data obtained from the k-space data, signals from an unnecessary substance are removed, and phase data for eddy current correction are calculated by using a part of the k-space data.
摘要翻译： 在消除从代谢物测量信号所不必要的信号的同时，在短时间内获得涡流校正所需的数据。 除去不是测量对象的不必要物质的信号，并且通过单次测量获得用于校正由涡流引起的光谱失真的相位数据。 调整强度的两种频率选择脉冲，使得来自不需要的物质的信号应具有相同的强度绝对值和相反的极性，对于至少一个轴的每个相位编码的变化强度，并且获得的信号 被布置在k空间中。 通过去除从k空间数据获得的图像数据的混叠，去除来自不需要的物质的信号，并且通过使用k空间数据的一部分来计算用于涡流校正的相位数据。
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公开(公告)号：US06744251B2
公开(公告)日：2004-06-01
申请号：US10309150
申请日：2002-12-04
IPC分类号： G01V300
CPC分类号： G01R33/4833
摘要： A nuclear-magnetic-resonance inspection apparatus that enables an examiner to designate directly a section of a subject to be imaged. The NMR inspection apparatus has a section-designating unit containing reference objects A, B, and C that can be set at three reference points, and can be held in the hand of an examiner to be moved and operated in close proximity to the subject, wherein a prescribed part of a plane including the reference objects set at up to three reference points is the section of the subject to be imaged. While watching the subject, the examiner can directly designate a section to be imaged. Thus, diagnoses can be made easily and quickly.
摘要翻译： 核磁共振检查装置，使得检查者能够直接指定待成像对象的一部分。 NMR检查装置具有包含可设置在三个参考点上的参考对象A，B和C的区段指定单元，并且可以保持在检查者的手中，以便靠近对象移动和操作， 其中包括设置在多达三个参考点处的参考对象的平面的规定部分是待成像对象的部分。 在观看主题的同时，审查员可以直接指定要成像的部分。 因此，可以容易且快速地进行诊断。
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公开(公告)号：US5449707A
公开(公告)日：1995-09-12
申请号：US177270
申请日：1994-01-04
IPC分类号： C08F8/44 , C08F283/01 , C08J3/03 , C08L67/06
CPC分类号： C08J3/03 , C08F283/01 , C08F8/44 , C08J2351/08 , C08J2367/06
摘要： An aqueous dispersion of a graft-copolymer (A), dispersed in water or a mixed solvent (B) of water and a water-soluble organic solvent, the graft-copolymer (A) comprising a polyester (A-a) graft-polymerized with a radical copolymerizable monomer (A-b) comprising a radical copolymerizable monomer having a hydrophilic group, wherein said graft-copolymer (A) is dispersed as fine particles having an average particle size of not more than 500 nm and a half band width of a signal of a carbon of a carbonyl group of the polyester, as determined by .sup.13 C-NMR, is not less than 300 Hz. The aqueous polyester dispersion of the present invention is superior in re-dispersibility and when a paint prepared from the dispersion is coated on a metal or a plastic, the coated film shows superior appearance, processability and water resistance. Accordingly, the aqueous dispersion of the present invention serves well for use for paints, ink, coating agents, adhesives and various treating agents.
摘要翻译： 接枝共聚物（A）的水分散体（A），分散在水或水和水溶性有机溶剂的混合溶剂（B）中，所述接枝共聚物（A）包含接枝共聚物 自由基可共聚单体（Ab），其包含具有亲水基团的自由基可共聚单体，其中所述接枝共聚物（A）作为平均粒径不大于500nm的细颗粒和信号的半带宽分散 通过13 C-NMR测定的聚酯的羰基碳不小于300Hz。 本发明的水性聚酯分散体的再分散性优异，当由分散体制备的涂料涂覆在金属或塑料上时，涂膜具有优异的外观，加工性和耐水性。 因此，本发明的水性分散体很好地用于油漆，油墨，涂布剂，粘合剂和各种处理剂。
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公开(公告)号：US20080122440A1
公开(公告)日：2008-05-29
申请号：US11987083
申请日：2007-11-27
IPC分类号： G01R33/483
CPC分类号： G01R33/56341
摘要： The present invention provides a measurement system and an image processing system for quantitatively figuring out the fiber bundles which are passing through any VOI. A static magnetic field and an RF signal are applied to a subject, and a nuclear magnetic resonance signal is received from the subject (401). Diffusion tensor is calculated from the nuclear magnetic resonance signals (402). As to a target area for receiving the nuclear magnetic resonance signal from the subject, fiber bundles passing through multiple predetermined origins, respectively, are extracted in a form of a group of coordinate points for each of the fiber bundles, based on the diffusion tensor calculated by the calculating means (406). At least one VOI is set for the target area for receiving the nuclear magnetic resonance signal (408). Out of the multiple fiber bundles extracted by the fiber bundle extracting means, the fiber bundles having at least one coordinate point of the group of coordinate points being included in the VOI are discriminated and the number of which is counted (409).
摘要翻译： 本发明提供一种测量系统和图像处理系统，用于定量地计算穿过任何VOI的纤维束。 对被检体施加静磁场和RF信号，从受检者（401）接收核磁共振信号。 从核磁共振信号（402）计算扩散张量。 对于从对象接收核磁共振信号的目标区域，分别通过多个预定起点的纤维束以每个纤维束的一组坐标点的形式，基于计算出的扩散张量来提取 通过计算装置（406）。 至少一个VOI被设置用于接收核磁共振信号的目标区域（408）。 在由纤维束提取装置提取的多个光纤束中，鉴别具有包括在VOI中的坐标点组中的至少一个坐标点的光纤束，并且其数量被计数（409）。
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10.发明申请公开(公告)号：US20070038076A1
公开(公告)日：2007-02-15
申请号：US11356010
申请日：2006-02-17
申请人： Akiko Osada , Yukari Yamamoto , Yo Taniguchi
发明人： Akiko Osada , Yukari Yamamoto , Yo Taniguchi
IPC分类号： A61B5/05
CPC分类号： G01R33/5601 , G01R33/282
摘要： The invention provides an MRI apparatus capable of using a static magnetic filed magnet provided therein as a magnet for polarization, and performing DNP therein without changing a construction of a conventional MRI apparatus. A DNP means placed in the MRI apparatus includes a sample tube, cooling units for cooling and solidifying a sample in the sample tube, a microwave irradiating unit, and a metal tube. At least a member placed near an imaging space (five-gauss line) of the MRI apparatus is made of a nonmagnetic material, and a static magnetic field generating magnet of the MRI apparatus is used as a magnetic field applying means for applying a magnetic field to the sample for polarization. A contrast agent generated by the DNP can be immediately injected into a patient for imaging, so as to provide an image with high S/N.
摘要翻译： 本发明提供一种MRI设备，其能够使用其中提供的静磁磁体作为磁极用于极化，并且在不改变常规MRI设备的结构的情况下执行DNP。 放置在MRI装置中的DNP装置包括样品管，用于冷却固化样品管中的样品的冷却单元，微波照射单元和金属管。 位于MRI装置的成像空间（五高斯线）附近的至少一个构件由非磁性材料制成，MRI装置的静磁场产生磁体用作施加磁场的磁场施加装置 到样品进行极化。 由DNP产生的造影剂可以立即注射到患者进行成像，以提供高S / N的图像。
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