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    Silica Composite Capsules Obtained By Blending Water-Soluble Silane Derivative, Composition Containg The Same, And Transparent Gel-Form Composition
    1.
    发明申请
    Silica Composite Capsules Obtained By Blending Water-Soluble Silane Derivative, Composition Containg The Same, And Transparent Gel-Form Composition 失效
    通过混合水溶性硅烷衍生物获得的二氧化硅复合胶囊，含有它的组合物和透明的凝胶形式组合物

    公开(公告)号：US20100016200A1

    公开(公告)日：2010-01-21

    申请号：US12440614

    申请日：2007-09-11

    申请人： Yuko Nagare ,  Kei Watanabe ,  Kazutami Sakamoto ,  Shun Takahashi ,  Teruhiko Hineno

    发明人： Yuko Nagare ,  Kei Watanabe ,  Kazutami Sakamoto ,  Shun Takahashi ,  Teruhiko Hineno

    IPC分类号： A61K8/06

    CPC分类号： A61Q19/10 ,  A61K8/0291 ,  A61K8/0295 ,  A61K8/042 ,  A61K8/11 ,  A61K8/25 ,  A61K8/585 ,  A61K2800/262 ,  A61K2800/412 ,  A61Q1/02

    摘要： The present invention provides new silica composite capsules that can be easily prepared, a composition containing the silica composite capsules, and a transparent gel-form composition excellent in appearance transparency and texture in use, and in particular, a transparent gel-form composition with improved cleansing properties when used as a cleanser. Micelle/silica composite capsules can easily be obtained, in an aqueous system, by mixing a material capable of forming micelles in water and a water-soluble silane derivative having a specific structure in aqueous solution. In addition, emulsion/silica composite capsules wherein the periphery of emulsion particles in the inner phase is coated with silica, can easily be obtained by mixing a surfactant, water, an oil, and a water-soluble silane derivative having a specific structure. Moreover, a transparent gel-form composition showing excellent appearance transparency, the texture in use and cleansing properties, can be obtained by blending a water-soluble silane derivative having a specific structure into the formulation that contains a surfactant, an oil and water, and capable of taking a surfactant association structure with aqueous continuous phase or both of aqueous continuous phase and oil continuous phase in the formulation.

    摘要翻译： 本发明提供了可以容易地制备的新的二氧化硅复合胶囊，含有二氧化硅复合胶囊的组合物，以及外观透明性和使用质地优异的透明凝胶状组合物，特别是具有改进的透明凝胶状组合物 用作清洁剂时的清洁性能。 通过将能够在水中形成胶束的材料和在水溶液中具有特定结构的水溶性硅烷衍生物混合，可以在水性体系中容易地获得胶束/二氧化硅复合胶囊。 此外，通过混合表面活性剂，水，油和具有特定结构的水溶性硅烷衍生物，可以容易地得到内层的乳液粒子的周围用二氧化硅涂布的乳液/二氧化硅复合胶囊。 此外，通过将具有特定结构的水溶性硅烷衍生物掺入含有表面活性剂，油和水的配方中，可以获得表现出优异的外观透明度，使用质地和清洁性能的透明凝胶状组合物，以及 能够在制剂中具有含水连续相或水相连续相和油连续相的表面活性剂缔合结构。

    Silica composite capsules obtained by blending water-soluble silane derivative, composition containing the same, and transparent gel-form composition
    2.
    发明授权
    Silica composite capsules obtained by blending water-soluble silane derivative, composition containing the same, and transparent gel-form composition 失效
    通过混合水溶性硅烷衍生物，含有它们的组合物和透明凝胶状组合物获得的二氧化硅复合胶囊

    公开(公告)号：US08030267B2

    公开(公告)日：2011-10-04

    申请号：US12440614

    申请日：2007-09-11

    申请人： Yuko Nagare ,  Kei Watanabe ,  Kazutami Sakamoto ,  Shun Takahashi ,  Teruhiko Hineno

    发明人： Yuko Nagare ,  Kei Watanabe ,  Kazutami Sakamoto ,  Shun Takahashi ,  Teruhiko Hineno

    IPC分类号： C11D9/36 ,  C11D3/44

    CPC分类号： A61Q19/10 ,  A61K8/0291 ,  A61K8/0295 ,  A61K8/042 ,  A61K8/11 ,  A61K8/25 ,  A61K8/585 ,  A61K2800/262 ,  A61K2800/412 ,  A61Q1/02

    摘要： The present invention provides new silica composite capsules that can be easily prepared, a composition containing the silica composite capsules, and a transparent gel-form composition excellent in appearance transparency and texture in use, and in particular, a transparent gel-form composition with improved cleansing properties when used as a cleanser. Micelle/silica composite capsules can easily be obtained, in an aqueous system, by mixing a material capable of forming micelles in water and a water-soluble silane derivative having a specific structure in aqueous solution. In addition, emulsion/silica composite capsules wherein the periphery of emulsion particles in the inner phase is coated with silica, can easily be obtained by mixing a surfactant, water, an oil, and a water-soluble silane derivative having a specific structure. Moreover, a transparent gel-form composition showing excellent appearance transparency, the texture in use and cleansing properties, can be obtained by blending a water-soluble silane derivative having a specific structure into the formulation that contains a surfactant, an oil and water, and capable of taking a surfactant association structure with aqueous continuous phase or both of aqueous continuous phase and oil continuous phase in the formulation.

    摘要翻译： 本发明提供了可以容易地制备的新的二氧化硅复合胶囊，含有二氧化硅复合胶囊的组合物，以及外观透明性和使用质地优异的透明凝胶状组合物，特别是具有改进的透明凝胶状组合物 用作清洁剂时的清洁性能。 通过将能够在水中形成胶束的材料和在水溶液中具有特定结构的水溶性硅烷衍生物混合，可以在水性体系中容易地获得胶束/二氧化硅复合胶囊。 此外，通过混合表面活性剂，水，油和具有特定结构的水溶性硅烷衍生物，可以容易地得到内层的乳液粒子的周围用二氧化硅涂布的乳液/二氧化硅复合胶囊。 此外，通过将具有特定结构的水溶性硅烷衍生物掺入含有表面活性剂，油和水的配方中，可以获得表现出优异的外观透明度，使用质地和清洁性能的透明凝胶状组合物，以及 能够在制剂中具有含水连续相或水相连续相和油连续相的表面活性剂缔合结构。

    Composition Containing Vesicle-Silica Complex, And Process For Production Thereof
    5.
    发明申请
    Composition Containing Vesicle-Silica Complex, And Process For Production Thereof 审中-公开
    含有囊泡 - 二氧化硅复合物的组合物及其制备方法

    公开(公告)号：US20100215703A1

    公开(公告)日：2010-08-26

    申请号：US12675462

    申请日：2008-08-27

    申请人： Kei Watanabe ,  Yuko Nagare

    发明人： Kei Watanabe ,  Yuko Nagare

    IPC分类号： A61K8/02 ,  A61K8/25 ,  A61Q13/00 ,  A61Q90/00 ,  A61K8/14

    CPC分类号： A61Q13/00 ,  A61K8/14 ,  A61K8/25 ,  A61K8/585 ,  B01J13/04 ,  B01J13/22

    摘要： To provide a vesicle-containing composition wherein the stability is improved and the rate of releasing drug or perfume is sufficiently restricted during administration in vivo or application to the skin surface. Silica polymerization on the outer surfaces of vesicles is facilitated by adding a specifically structured water-soluble silane derivative to an aqueous composition containing the vesicles composed of a surfactant and mixing them together, and vesicle-silica composites having silica-coated outer surfaces can be obtained, resulting in the improved stability of the vesicle-containing composition as well as the improved effect of restricting the rate of releasing drug or perfume during administration in vivo or application to the skin surface.

    摘要翻译： 提供一种含囊泡的组合物，其中稳定性得到改善，并且释放药物或香料的速率在体内施用或施用于皮肤表面时被充分地限制。 通过将特定结构的水溶性硅烷衍生物加入含有由表面活性剂构成的囊泡的水性组合物并混合在一起，可以获得囊泡外表面的二氧化硅聚合，并且可以获得具有二氧化硅涂覆的外表面的囊泡 - 二氧化硅复合材料 导致含囊泡组合物的稳定性得到改善，以及在体内施用或施用于皮肤表面时限制释放药物或香料的速率的改进效果。

    Vesicle-Containing Composition And Production Method Thereof
    6.
    发明申请
    Vesicle-Containing Composition And Production Method Thereof 审中-公开
    含囊泡的组合物及其制备方法

    公开(公告)号：US20100080832A1

    公开(公告)日：2010-04-01

    申请号：US12598781

    申请日：2008-05-15

    申请人： Kei Watanabe ,  Hidefumi Araki ,  Yuko Nagare ,  Yasunari Nakama ,  Hirokazu Ishino

    发明人： Kei Watanabe ,  Hidefumi Araki ,  Yuko Nagare ,  Yasunari Nakama ,  Hirokazu Ishino

    IPC分类号： A61K8/11 ,  B01J13/02 ,  A61Q13/00

    CPC分类号： A61K8/0241 ,  A61K8/14 ,  A61K8/34 ,  A61K8/345 ,  A61K8/891 ,  A61K8/894 ,  A61Q5/12 ,  A61Q13/00 ,  A61Q19/00

    摘要： To provide a vesicle-containing composition wherein a perfume component is stably incorporated in the vesicle bilayer membrane composed of a silicone surfactant and to provide a simple production method of the vesicle-containing composition wherein a perfume component is stably incorporated. A vesicle-containing composition comprising; (A) a perfume, (B) a silicone oil, (C) a silicone surfactant, (D) one or more selected from the group consisting of ethanol, propylene glycol, dipropylene glycol, and 1,3-butylene glycol, and (E) water; wherein the (C) silicone surfactant forms vesicles, and the (A) perfume and the (B) silicone oil are present in the vesicle bilayer membrane.

    摘要翻译： 本发明提供一种含有囊泡的组合物，其中将香料成分稳定地并入由硅氧烷表面活性剂构成的囊泡双层膜中，并提供其中稳定地配合香料成分的含囊泡组合物的简单制造方法。 一种含囊泡的组合物，其包含： （A）香料，（B）硅油，（C）有机硅表面活性剂，（D）选自乙醇，丙二醇，二丙二醇和1,3-丁二醇中的一种或多种，​​和（D） E）水; 其中（C）硅氧烷表面活性剂形成囊泡，并且（A）香料和（B）硅油存在于泡囊双层膜中。

    WATER-SOLUBLE METAL ALCOHOLATE DERIVATIVES, PRODUCTION METHODS THEREOF, AND SOLID GELATINOUS EXTERNAL PREPARATIONS CONTAINING THE SAME
    7.
    发明申请
    WATER-SOLUBLE METAL ALCOHOLATE DERIVATIVES, PRODUCTION METHODS THEREOF, AND SOLID GELATINOUS EXTERNAL PREPARATIONS CONTAINING THE SAME 审中-公开
    水溶性金属醇盐衍生物，其生产方法和含有其的固体外消旋制剂

    公开(公告)号：US20090149554A1

    公开(公告)日：2009-06-11

    申请号：US12063275

    申请日：2006-08-11

    申请人： Yuko Ishikawa ,  Katzutami Sakamoto ,  Toshikhiko Seki ,  Isao Yajima ,  Shun Takahashi ,  Kei Watanabe

    发明人： Yuko Ishikawa ,  Katzutami Sakamoto ,  Toshikhiko Seki ,  Isao Yajima ,  Shun Takahashi ,  Kei Watanabe

    IPC分类号： A61K47/24 ,  C07F7/28 ,  C07F7/02

    CPC分类号： C07F7/045 ,  A61K9/0014 ,  A61K47/10 ,  C07C31/20

    摘要： The object of the present invention is to provide a production method of water-soluble silane derivatives, the separation and purification of which are easy, and the reaction for which can be conducted under an industrially practicable temperature condition (under the temperature condition of 90° C. or lower) and to provide compounds with which solid gelatinous external preparations, with excellent stability against a temperature change and against an effect of additives and with excellent usability, can be prepared. The water-soluble silane derivative could be formed by the substitution reaction of a metal alkoxide with a polyhydric alcohol under the presence of a solid catalyst. According to this production method, the separation of the catalyst from the product is very easy, and the reaction can be carried out under the temperature condition of 90° C. or lower. The obtained water-soluble metal alcoholate derivative can satisfactory solidify an aqueous formulation of an external preparation by its blending thereinto. The obtained solid gelatinous external preparation has excellent stability against a temperature change and against the effect of additives. In addition, the external preparation is easily disintegrated during use; thus the usability such as easiness to be scooped up with fingers and spreadability during application is excellent.

    摘要翻译： 本发明的目的是提供一种水溶性硅烷衍生物的制造方法，其分离纯化容易，其反应可以在工业上可行的温度条件下（在90℃的温度条件下进行） C.或更低），并且可以制备具有优异的耐温度变化稳定性和抗添加剂效果以及优异可用性的固体胶状外用制剂的化合物。 水溶性硅烷衍生物可以通过金属醇盐与多元醇在固体催化剂存在下的取代反应形成。 根据该制造方法，催化剂与产物的分离非常容易，反应可以在90℃以下的温度条件下进行。 所得到的水溶性金属醇化物衍生物可以通过其混合来使外用制剂的水性制剂充分固化。 所得固体凝胶状外用制剂对温度变化和添加剂的效果具有优异的稳定性。 此外，外用制剂在使用过程中容易分解; 因此在使用时易于用手指舀起的可用性和铺展性优异。

    Cosmetic composition
    8.
    发明授权
    Cosmetic composition 有权

    公开(公告)号：US09655830B2

    公开(公告)日：2017-05-23

    申请号：US13519348

    申请日：2010-12-27

    申请人： Minako Sato ,  Takashi Teshigawara ,  Kei Watanabe

    发明人： Minako Sato ,  Takashi Teshigawara ,  Kei Watanabe

    IPC分类号： A61Q19/00 ,  A61K8/55 ,  A61K8/34 ,  A61K8/36

    CPC分类号： A61K8/553 ,  A61K8/342 ,  A61K8/345 ,  A61K8/361 ,  A61K2800/262 ,  A61Q19/00

    摘要： To provide a transparent to translucent cosmetic composition which is highly stable, and can impart excellent actual feelings of effectiveness in use, such as a feeling of skin penetration, a feeling of non-stickiness, and a skin-softening effect after application thereof to the skin. A transparent to translucent cosmetic composition comprising: (a) a hydrogenated phospholipid, (b) one or more selected from among branched higher fatty acids and higher alcohols, and (c) a polyalcohol that acts as a good solvent and/or a poor solvent for component (a). Preferably, component (b) is isostearic acid and/or isostearyl alcohol. Preferably, the ratio of component (a)/component (b) is from 1/0.01 to 1/0.4 (by mass).

    Separator and method for manufacturing separator
    9.
    发明授权
    Separator and method for manufacturing separator 有权
    分离器和制造分离器的方法

    公开(公告)号：US09177729B2

    公开(公告)日：2015-11-03

    申请号：US13977711

    申请日：2012-02-06

    申请人： Ick-soo Kim ,  Byoung-Suhk Kim ,  Kei Watanabe ,  Naotaka Kimura ,  Kyu-oh Kim ,  Jae-hwan Lee

    发明人： Ick-soo Kim ,  Byoung-Suhk Kim ,  Kei Watanabe ,  Naotaka Kimura ,  Kyu-oh Kim ,  Jae-hwan Lee

    IPC分类号： H01G9/02 ,  H01M2/14 ,  H01M2/16

    CPC分类号： H01G9/02 ,  H01M2/145 ,  H01M2/162 ,  H01M2/1686

    摘要： The present invention provides a separator and a method for manufacturing the separator. The separator includes a first nanofiber layer (20) which has a lattice shape when viewed from a plan view, a second nanofiber layer (30) which is provided on a first surface of the first nanofiber layer (20) and is thinner than the first nanofiber layer, and a third nanofiber layer (40) which is provided on a second surface of the first nanofiber layer and is thinner than the first nanofiber layer. The thickness of the first nanofiber layer ranges from 7 μm to 30 μm. The thickness of each of the second and third nanofiber layers ranges from 1 μm to 5 μm. The present invention can provide a separator which has high insulation, high dendrite resistance, high ion conductivity and high mechanical strength.

    摘要翻译： 本发明提供一种分离器及其制造方法。 所述隔板包括从平面观察时具有格子状的第一纳米纤维层（20），设置在所述第一纳米纤维层（20）的第一面上且比所述第一纳米纤维层薄 纳米纤维层和设置在第一纳米纤维层的第二表面上并且比第一纳米纤维层薄的第三纳米纤维层（40）。 第一纳米纤维层的厚度为7μm〜30μm。 第二和第三纳米纤维层的厚度范围为1μm至5μm。 本发明可以提供绝缘性高，耐枝晶性高，离子电导率高，机械强度高的隔膜。