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    Sound insulating structure
    1.
    发明授权
    Sound insulating structure 失效
    隔音结构

    公开(公告)号：US5677027A

    公开(公告)日：1997-10-14

    申请号：US584278

    申请日：1996-01-11

    申请人： Yuugorou Masuda ,  Shousuke Oku ,  Masashi Ito ,  Tomohiro Ito ,  Hiroshi Sugawara

    发明人： Yuugorou Masuda ,  Shousuke Oku ,  Masashi Ito ,  Tomohiro Ito ,  Hiroshi Sugawara

    IPC分类号： B32B5/02 ,  B32B7/02 ,  B32B27/02 ,  B60N3/04 ,  B60R13/08 ,  D04H1/55 ,  G10K11/168 ,  B32B3/02

    CPC分类号： B60R13/083 ,  B32B27/02 ,  B60N3/048 ,  D04H1/54 ,  G10K11/168 ,  Y10T428/23979 ,  Y10T428/23986 ,  Y10T442/641 ,  Y10T442/656

    摘要： The disclosure relates to a sound insulating structure formed on an automobile floor panel on which at least one of a vibration and a sound is incident. This structure includes a covering layer for covering the panel and a cushioning layer for reducing an impact of the at least one of the vibration and the sound. This cushioning layer is interposed between the covering layer and the panel and made of a nonwoven fabric. This nonwoven fabric includes 5-95 wt % of a first fiber and 5-95% of a second fiber, wherein the total amount of the first and second fibers is 100 wt %. This first fiber has a fineness within a range from 1.5 to 40 deniers, a first melting point, and a first portion including polyethylene terephthalate. The second fiber has a fineness within a range from 1.5 to 15 deniers, a core portion, and a sheath portion covering the core portion. A majority of the core portion includes polyethylene terephthalate. The sheath portion includes an elastic copolyester which has a second melting point that is lower than the first melting point and is not higher than 200.degree. C. The elastic copolyester is prepared by copolymerizing polyethylene terephthalate and at least one other monomer. The sound insulating structure has a high sound-transmission-loss factor within a so-called road-noise frequency range and an adequate cushioning effect and is particularly superior in sound insulating at a normal temperature (15.degree.-40.degree. C.).

    摘要翻译： 本公开涉及一种形成在汽车地板上的隔音结构，其中振动和声音中的至少一个入射。 该结构包括用于覆盖面板的覆盖层和用于减少振动和声音中的至少一个的冲击的缓冲层。 该缓冲层插入在覆盖层和面板之间，由无纺布构成。 该无纺布包括5-95重量％的第一纤维和5-95％的第二纤维，其中第一和第二纤维的总量为100重量％。 该第一纤维的细度在1.5至40旦，第一熔点和包含聚对苯二甲酸乙二醇酯的第一部分的范围内。 第二纤维的细度在1.5至15旦的范围内，芯部分和覆盖芯部分的护套部分。 核心部分的大部分包括聚对苯二甲酸乙二醇酯。 护套部分包括具有低于第一熔点且不高于200℃的第二熔点的弹性共聚酯。弹性共聚酯通过聚对苯二甲酸乙二醇酯和至少一种其它单体共聚来制备。 隔音结构在所谓的道路噪声频率范围内具有高的声音传输损耗因数，并具有足够的缓冲效果，并且在常温（15°-40℃）下隔音性能特别优异。

    POLYPHENYLENE SULFIDE FIBER AND NONWOVEN FABRIC
    2.
    发明申请
    POLYPHENYLENE SULFIDE FIBER AND NONWOVEN FABRIC 审中-公开
    聚苯乙烯纤维和非织造布

    公开(公告)号：US20140187115A1

    公开(公告)日：2014-07-03

    申请号：US14122114

    申请日：2012-06-01

    申请人： Yohei Nakano ,  Yoshikazu Yakake ,  Masashi Ito

    发明人： Yohei Nakano ,  Yoshikazu Yakake ,  Masashi Ito

    IPC分类号： D01F6/76 ,  D04H1/4326

    CPC分类号： D01F6/765 ,  D01D5/08 ,  D04H1/4326 ,  D04H1/44 ,  D04H1/54 ,  Y10T442/60 ,  Y10T442/69

    摘要： Provided are a polyphenylene sulfide fiber including a PPS resin as a main component and having both excellent heat resistance and excellent thermal bonding properties, and a nonwoven fabric including the fiber. The polyphenylene sulfide fiber includes polyphenylene sulfide as a main component and having the sum of the crystallinity and the rigid amorphous fraction of 30% to 90%. The crystallinity is preferably not less than 5% and less than 25%. The polyphenylene sulfide fiber is used to form a nonwoven fabric. The nonwoven fabric is preferably produced by consolidation by thermal bonding or mechanical entanglement.

    摘要翻译： 提供以PPS树脂为主要成分，具有优异的耐热性和优异的热粘合性的聚苯硫醚纤维，以及包含该纤维的无纺布。 聚苯硫醚纤维包括聚苯硫醚作为主要成分，其结晶度和刚性非晶部分之和为30％至90％。 结晶度优选为5％以上且小于25％。 聚苯硫醚纤维用于形成无纺织物。 无纺布优选通过热粘合或机械缠结固结而制成。

    Primary cultured adipocytes for gene therapy
    6.
    发明授权
    Primary cultured adipocytes for gene therapy 有权
    原代培养的脂肪细胞进行基因治疗

    公开(公告)号：US08071085B2

    公开(公告)日：2011-12-06

    申请号：US12175186

    申请日：2008-07-17

    申请人： Masashi Ito ,  Yasushi Saito

    发明人： Masashi Ito ,  Yasushi Saito

    IPC分类号： A61K48/00 ,  C12P21/00 ,  C12P21/02

    CPC分类号： C12N5/0653 ,  A61K35/12 ,  C12N2510/00 ,  C12N2510/02

    摘要： The present invention relates to primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. This invention provides cells suitable for gene therapy, which can replace bone marrow cells and liver cells used for conventional ex vivo gene therapy. The present invention established methods for transferring foreign genes into primary cultured adipocytes, which are suitable for ex vivo gene therapy; can be easily collected and implanted; and can be removed after implantation. Specifically, the present invention established these methods that use retroviral vectors. The present invention also established primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells.

    摘要翻译： 本发明涉及用于基因治疗的原代培养的脂肪细胞，其中脂肪细胞稳定地维持编码在细胞外分泌的蛋白质的外源基因。 本发明提供适用于基因治疗的细胞，其可代替用于常规体外基因治疗的骨髓细胞和肝细胞。 本发明建立了将外源基因转移到适合离体基因治疗的原代培养脂肪细胞中的方法; 可以轻松收集和植入; 并且可以在植入后去除。 具体地，本发明建立了使用逆转录病毒载体的这些方法。 本发明还建立了用于基因治疗的原代培养的脂肪细胞，其中脂肪细胞稳定地保持编码在细胞外分泌的蛋白质的外源基因。

    Spectroscopic module
    7.
    发明授权
    Spectroscopic module 失效
    光谱模块

    公开(公告)号：US08045155B2

    公开(公告)日：2011-10-25

    申请号：US12377343

    申请日：2008-06-05

    申请人： Tomofumi Suzuki ,  Katsumi Shibayama ,  Takafumi Yokino ,  Masashi Ito ,  Helmut Teichmann ,  Dietmar Hiller ,  Ulrich Starker

    发明人： Tomofumi Suzuki ,  Katsumi Shibayama ,  Takafumi Yokino ,  Masashi Ito ,  Helmut Teichmann ,  Dietmar Hiller ,  Ulrich Starker

    IPC分类号： G01J3/26

    CPC分类号： G01J3/02 ,  G01J3/0208 ,  G01J3/0243 ,  G01J3/0259 ,  G01J3/04

    摘要： The spectroscopy module is provided with a body portion for transmitting light, a spectroscopic portion for dispersing light made incident from the front plane of the body portion into the body portion to reflect the light on the front plane, a light detecting element having a light detecting portion for detecting the light dispersed and reflected by the spectroscopic portion and electrically connected to a wiring formed on the front plane of the body portion by face-down bonding, and an underfill material filled in the body portion side of the light detecting element to transmit the light. The light detecting element is provided with a light-passing hole through which the light advancing into the spectroscopic portion passes, and a reservoir portion is formed on a rear plane of the body portion side in the light detecting element so as to enclose a light outgoing opening of the light-passing hole.

    摘要翻译： 光谱模块设置有用于透射光的主体部分，用于将从主体部分的前平面入射的光分散到主体部分中以将光反射到前平面上的光谱部分，具有光检测的光检测元件 用于检测由分光部分分散和反射的光并通过面朝下接合与形成在主体部分的前平面上的布线电连接的光;以及填充在光检测元件的主体部分侧的底部填充材料， 光。 光检测元件设置有通向分光部分的光通过的通光孔，并且在光检测元件中的主体部分侧的后平面上形成储存部分，以便包围光出射 打开通光孔。

    Method for Manufacturing Optically Active Tetrahydrothiophene Derivative and Method for Crystallization of Optically Active Tetrahydrothiophene-3-Ol
    9.
    发明申请
    Method for Manufacturing Optically Active Tetrahydrothiophene Derivative and Method for Crystallization of Optically Active Tetrahydrothiophene-3-Ol 审中-公开
    光学活性四氢噻吩衍生物的制备方法和光活性四氢噻吩-3-O的结晶方法

    公开(公告)号：US20080050787A1

    公开(公告)日：2008-02-28

    申请号：US10581366

    申请日：2004-12-01

    申请人： Hazuki Nagai ,  Kaname Konuki ,  Masashi Ito ,  Tomohiro Sameshima

    发明人： Hazuki Nagai ,  Kaname Konuki ,  Masashi Ito ,  Tomohiro Sameshima

    IPC分类号： C12P17/00 ,  C07D333/32

    CPC分类号： C12P17/167

    摘要： A method for manufacturing (R)-tetrahydrothiophene-3-ol denoted by formula (II): by bioconversion of tetrahydrothiophene-3-one denoted by formula (I): to (R)-tetrahydrothiophene-3-ol denoted by formula (II). It comprises the steps of: (A) incubating the tetrahydrothiophene-3-one denoted by formula (I) in the presence of a strain, or a preparation of a cultured cell thereof, belonging to Penicillium, Aspergillus, or Streptomyces that is capable of said bioconversion; and (B) collecting the (R)-tetrahydrothiophene-3-ol denoted by formula (II) from incubated solution. A method for crystallization of optically active tetrahydrothiophene-3-ol of improved optical purity, characterized by maintaining a solution comprising optically active tetrahydrothiophene-3-ol and organic solvent at equal to or lower than 1° C. to cause optically active tetrahydrothiophene-3-ol to crystallize from said solution, or characterized by adding optically active tetrahydrothiophene-3-ol dropwise to organic solvent at a solution temperature of equal to or lower than 1° C. to cause optically active tetrahydro thiophene-3-ol to crystallize.

    摘要翻译： 由式（II）表示的（R） - 四氢噻吩-3-醇的制造方法：通过式（I）表示的四氢噻吩-3-酮的生物转化：式（II）表示的（R） - 四氢噻吩-3-醇 ）。 其包括以下步骤：（A）在菌株存在下将式（I）表示的四氢噻吩-3-酮或其培养细胞的制剂，属于青霉属，曲霉属或链霉菌属，其能够 说生物转化 和（B）从温育溶液中收集由式（II）表示的（R） - 四氢噻吩-3-醇。 一种提高光学纯度的光学活性四氢噻吩-3-醇的结晶方法，其特征在于将含有光学活性四氢噻吩-3-醇和有机溶剂的溶液保持在等于或低于1℃，使光学活性的四氢噻吩-3 - 醇从所述溶液中结晶，或者特征在于在等于或低于1℃的溶液温度下将光学活性的四氢噻吩-3-醇滴加到有机溶剂中，使光学活性的四氢噻吩-3-醇结晶。

    Primarily cultured adipocytes for gene therapy
    10.
    发明申请
    Primarily cultured adipocytes for gene therapy 有权
    主要培养的脂肪细胞进行基因治疗

    公开(公告)号：US20060121008A1

    公开(公告)日：2006-06-08

    申请号：US10518472

    申请日：2003-06-18

    申请人： Masashi Ito ,  Yasushi Saito

    发明人： Masashi Ito ,  Yasushi Saito

    IPC分类号： A61K48/00 ,  C12N5/08 ,  C12N15/867 ,  C12N15/861

    CPC分类号： C12N5/0653 ,  A61K35/12 ,  C12N2510/00 ,  C12N2510/02

    摘要： The present invention relates to primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. This invention provides cells suitable for gene therapy, which can replace bone marrow cells and liver cells used for conventional ex vivo gene therapy. The present invention established methods for transferring foreign genes into primary cultured adipocytes, which are suitable for ex vivo gene therapy; can be easily collected and implanted; and can be removed after implantation. Specifically, the present invention established these methods that use retroviral vectors. The present invention also established primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells.

    摘要翻译： 本发明涉及用于基因治疗的原代培养的脂肪细胞，其中脂肪细胞稳定地维持编码在细胞外分泌的蛋白质的外源基因。 本发明提供适用于基因治疗的细胞，其可代替用于常规体外基因治疗的骨髓细胞和肝细胞。 本发明建立了将外源基因转移到适合离体基因治疗的原代培养脂肪细胞中的方法; 可以轻松收集和植入; 并且可以在植入后去除。 具体地，本发明建立了使用逆转录病毒载体的这些方法。 本发明还建立了用于基因治疗的原代培养的脂肪细胞，其中脂肪细胞稳定地保持编码在细胞外分泌的蛋白质的外源基因。