公开(公告)号：US20240269358A1

公开(公告)日：2024-08-15

申请号：US18583836

申请日：2024-02-21

Applicant: DEKA Products Limited Partnership

Inventor： Dirk A. van der Merwe ,  Kevin L. Grant ,  Michael J. Wilt ,  Todd A. Ballantyne ,  Jonathan P. Rosse ,  Catharine N. Flynn ,  Brian K. Yee

IPC: A61M1/16 ,  A61K33/00 ,  A61M1/14 ,  A61M1/26 ,  A61M1/30 ,  A61M1/34 ,  A61M1/36 ,  A61M5/172 ,  A61M60/113 ,  A61M60/268 ,  A61M60/37 ,  A61M60/427 ,  A61M60/43 ,  A61M60/837 ,  A61M60/847 ,  A61M60/851 ,  A61M60/892 ,  A61M60/894 ,  G16H20/40

CPC classification number: A61M1/1601 ,  A61K33/00 ,  A61M1/14 ,  A61M1/1524 ,  A61M1/154 ,  A61M1/155 ,  A61M1/156 ,  A61M1/15625 ,  A61M1/15632 ,  A61M1/1565 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/1613 ,  A61M1/1619 ,  A61M1/1654 ,  A61M1/1656 ,  A61M1/1658 ,  A61M1/166 ,  A61M1/1664 ,  A61M1/1666 ,  A61M1/1668 ,  A61M1/1692 ,  A61M1/267 ,  A61M1/301 ,  A61M1/34 ,  A61M1/341 ,  A61M1/3413 ,  A61M1/3609 ,  A61M1/3621 ,  A61M1/362227 ,  A61M1/36224 ,  A61M1/36225 ,  A61M1/36226 ,  A61M1/362264 ,  A61M1/362265 ,  A61M1/362266 ,  A61M1/3627 ,  A61M1/3672 ,  A61M5/172 ,  A61M60/113 ,  A61M60/268 ,  A61M60/37 ,  A61M60/427 ,  A61M60/43 ,  A61M60/837 ,  A61M60/847 ,  A61M60/851 ,  G16H20/40 ,  A61M1/1561 ,  A61M1/362261 ,  A61M1/3638 ,  A61M60/892 ,  A61M60/894 ,  A61M2205/12 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3379 ,  A61M2205/3569 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/65 ,  Y02A50/30 ,  Y02A90/10

Abstract: Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

公开(公告)号：US12059516B2

公开(公告)日：2024-08-13

申请号：US18358840

申请日：2023-07-25

Applicant: DEKA Products Limited Partnership

Inventor： Kevin L. Grant ,  James D. Dale ,  Michael J. Wilt ,  Jason A. Demers ,  David E. Collins ,  Brian D. Tracey

IPC: A61M1/16 ,  A61M1/00 ,  A61M1/36 ,  A61M39/10 ,  A61M60/113 ,  A61M60/268 ,  A61M60/37 ,  A61M60/427 ,  A61M60/523 ,  A61M60/546 ,  B01D61/30 ,  B01D61/32

CPC classification number: A61M1/16 ,  A61M1/1601 ,  A61M1/1633 ,  A61M1/1639 ,  A61M1/1652 ,  A61M1/1668 ,  A61M1/1682 ,  A61M1/3607 ,  A61M1/36225 ,  A61M1/362266 ,  A61M1/3627 ,  A61M1/85 ,  A61M39/1011 ,  A61M39/105 ,  A61M60/113 ,  A61M60/268 ,  A61M60/37 ,  A61M60/427 ,  A61M60/523 ,  A61M60/546 ,  B01D61/30 ,  B01D61/32 ,  A61M1/1656 ,  A61M1/166 ,  A61M1/1686 ,  A61M1/1696 ,  A61M1/3623 ,  A61M1/842 ,  A61M2205/12 ,  A61M2205/15 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/58 ,  A61M2209/08

Abstract: A blood circuit assembly for a dialysis unit may include an organizing tray, a pair of pneumatic pumps mounted to the organizing tray for circulating blood received from a patient through a circuit including a dialyzer unit and returned to the patient, an air trap mounted to the organizing tray arranged to remove air from blood circulating in the circuit, a pair of dialyzer connections arranged to connect to the inlet and outlet of a dialyzer unit, and a pair of blood line connectors, one inlet blood line connector for receiving blood from the patient and providing blood to the pneumatic pumps and the other outlet blood line connector for returning blood to the patient.

公开(公告)号：US11828279B2

公开(公告)日：2023-11-28

申请号：US16723053

申请日：2019-12-20

Applicant: DEKA Products Limited Partnership

Inventor： Michael J. Wilt ,  Dirk A. van der Merwe ,  James D. Dale ,  Brian D. Tracey ,  Kevin L. Grant ,  Jason A. Demers ,  Catharine N. Flynn

IPC: F04B43/073 ,  A61M1/26 ,  A61M1/36 ,  A61M1/16 ,  A61M1/28 ,  F04B7/02 ,  F04B43/00 ,  F17D3/00 ,  F04B9/109 ,  F04B49/06 ,  F04B49/22 ,  F04B45/02 ,  F04B53/16 ,  F04B53/10 ,  A61M60/268 ,  A61M60/113 ,  A61M60/531 ,  A61M60/37 ,  F04B13/02 ,  F04B53/06 ,  A61M60/523 ,  A61M60/43 ,  A61M60/892 ,  A61M60/894

CPC classification number: F04B43/0733 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/166 ,  A61M1/1639 ,  A61M1/1656 ,  A61M1/1664 ,  A61M1/1666 ,  A61M1/267 ,  A61M1/287 ,  A61M1/3638 ,  A61M1/3672 ,  A61M60/113 ,  A61M60/268 ,  A61M60/37 ,  A61M60/523 ,  A61M60/531 ,  F04B7/02 ,  F04B7/0216 ,  F04B9/109 ,  F04B13/02 ,  F04B43/00 ,  F04B45/02 ,  F04B49/06 ,  F04B49/22 ,  F04B53/06 ,  F04B53/10 ,  F04B53/16 ,  F17D3/00 ,  A61M60/43 ,  A61M60/892 ,  A61M60/894 ,  A61M2205/12 ,  A61M2205/128 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3337 ,  A61M2205/3368 ,  A61M2205/502 ,  A61M2205/52 ,  Y10T137/0324 ,  Y10T137/0379 ,  Y10T137/2521 ,  Y10T137/85978 ,  Y10T137/86139

Abstract: Systems for monitoring fluid flow in an extracorporeal blood circuit are described. The blood circuit of such systems can include plod pump having a pumping chamber of the blood pump separated from a control chamber of the blood pump by a flexible diaphragm. The control chamber can be configured to transmit positive or negative pressure to operate the diaphragm. The system can include a pressure sensor configured to measure pressure in the control chamber of the blood pump, and a controller configured to receive information from the pressure sensor and to control the delivery of pressure to the control chamber of the blood pump. The controller can also be configured to cause the application of a time-varying pressure waveform on the blood pump diaphragm during a fill-stroke of the blood pump, and to monitor a pressure variation in the control chamber measured by the pressure sensor. When so configured, such controller can transmit a value representing a magnitude of the measured pressure variation to a display associated with the extracorporeal blood circuit.

公开(公告)号：US11793915B2

公开(公告)日：2023-10-24

申请号：US17493758

申请日：2021-10-04

Applicant: DEKA Products Limited Partnership

Inventor： Michael J. Wilt ,  Jason A. Demers ,  Kevin L. Grant ,  Brian D. Tracey ,  James D. Dale

IPC: A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  A61M1/26 ,  A61M1/14

CPC classification number: A61M1/1601 ,  A61M1/154 ,  A61M1/155 ,  A61M1/1561 ,  A61M1/1565 ,  A61M1/15625 ,  A61M1/16 ,  A61M1/1621 ,  A61M1/1654 ,  A61M1/1694 ,  A61M1/267 ,  A61M1/3401 ,  A61M1/341 ,  A61M1/3413 ,  A61M1/3424 ,  A61M1/365 ,  A61M1/3609 ,  A61M1/3621 ,  A61M1/3638 ,  A61M1/3643 ,  A61M1/3644 ,  A61M1/3646 ,  A61M1/3649 ,  A61M1/3652 ,  A61M1/3672 ,  A61M1/36224 ,  A61M1/362261 ,  A61M1/362263 ,  A61M1/362265 ,  A61M1/362266 ,  A61M2205/07 ,  A61M2205/12 ,  A61M2205/123 ,  A61M2205/128 ,  A61M2205/15 ,  A61M2205/16 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/36 ,  A61M2205/505 ,  A61M2205/82 ,  A61M2205/8218 ,  A61M2205/8225 ,  Y10T137/87893

Abstract: The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.

公开(公告)号：US11779689B2

公开(公告)日：2023-10-10

申请号：US17393268

申请日：2021-08-03

Applicant: DEKA Products Limited Partnership

Inventor： Dirk A. van der Merwe ,  Kevin L. Grant ,  Michael J. Wilt

IPC: A61M1/16 ,  A61M5/172 ,  A61M1/14 ,  A61M1/34 ,  A61M1/36 ,  G16H20/40 ,  A61M60/268 ,  A61M1/26 ,  A61M1/30 ,  A61K33/00 ,  A61M60/43 ,  A61M60/113 ,  A61M60/851 ,  A61M60/427 ,  A61M60/847 ,  A61M60/837 ,  A61M60/37 ,  A61M60/892 ,  A61M60/894

CPC classification number: A61M1/1601 ,  A61K33/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/166 ,  A61M1/1613 ,  A61M1/1619 ,  A61M1/1654 ,  A61M1/1656 ,  A61M1/1658 ,  A61M1/1664 ,  A61M1/1666 ,  A61M1/1668 ,  A61M1/1692 ,  A61M1/267 ,  A61M1/301 ,  A61M1/34 ,  A61M1/341 ,  A61M1/3413 ,  A61M1/3609 ,  A61M1/3621 ,  A61M1/3627 ,  A61M1/3672 ,  A61M5/172 ,  A61M60/113 ,  A61M60/268 ,  A61M60/37 ,  A61M60/427 ,  A61M60/43 ,  A61M60/837 ,  A61M60/847 ,  A61M60/851 ,  G16H20/40 ,  A61M1/3638 ,  A61M60/892 ,  A61M60/894 ,  A61M2205/12 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3379 ,  A61M2205/3569 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/65 ,  Y02A50/30 ,  Y02A90/10

Abstract: Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

公开(公告)号：US20230287876A1

公开(公告)日：2023-09-14

申请号：US18321751

申请日：2023-05-22

Applicant: DEKA Products Limited Partnership

Inventor： Michael J. Wilt ,  Dirk A. van der Merwe ,  James D. Dale ,  Brian D. Tracey ,  Kevin L. Grant ,  Jason A. Demers ,  Catharine N. Flynn

IPC: F04B43/073 ,  A61M1/26 ,  A61M1/36 ,  A61M1/16 ,  A61M1/28 ,  F04B7/02 ,  F04B43/00 ,  F17D3/00 ,  F04B13/02 ,  F04B9/109 ,  F04B49/06 ,  F04B49/22 ,  F04B45/02 ,  F04B53/16 ,  F04B53/06 ,  F04B53/10 ,  A61M60/268 ,  A61M60/113 ,  A61M60/531 ,  A61M60/37 ,  A61M60/523

CPC classification number: F04B43/0733 ,  A61M1/267 ,  A61M1/3672 ,  A61M1/166 ,  A61M1/3638 ,  A61M1/287 ,  F04B7/02 ,  A61M1/1656 ,  F04B43/00 ,  A61M1/16 ,  F17D3/00 ,  F04B7/0216 ,  F04B13/02 ,  A61M1/1666 ,  A61M1/1639 ,  A61M1/1664 ,  F04B9/109 ,  F04B49/06 ,  F04B49/22 ,  F04B45/02 ,  F04B53/16 ,  F04B53/06 ,  F04B53/10 ,  A61M1/1605 ,  A61M60/268 ,  A61M60/113 ,  A61M60/531 ,  A61M60/37 ,  A61M60/523 ,  A61M2205/3331 ,  A61M2205/3337 ,  A61M2205/502 ,  A61M2205/3317 ,  A61M2205/3368 ,  A61M2205/52 ,  A61M2205/15 ,  A61M2205/18 ,  Y10T137/85978 ,  A61M2205/128 ,  A61M2205/3324 ,  Y10T137/86139 ,  Y10T137/0379 ,  Y10T137/0324 ,  Y10T137/2521 ,  A61M2205/12 ,  A61M60/43

Abstract: Hemodialysis and similar dialysis systems including a variety of systems and methods that make hemodialysis more efficient, easier, and/or more affordable, and include new fluid circuits for fluid flow in hemodialysis systems and a reciprocating diaphragm pump for pumping fluids. The reciprocating diaphragm pump includes a flexible diaphragm, a first rigid body having a curved pumping chamber wall, a second rigid body having an opposing curved control chamber wall. The diaphragm is interposed between the pumping chamber wall and the control chamber wall to define a pumping chamber and a control chamber. The diaphragm of the pump has a peripheral bead arranged to locate the diaphragm between the first rigid body and the second rigid body and a diaphragm body having a curved, semi-spheroid or domed shape. The diaphragm is pre-formed or molded so that during a delivery stroke of the pump, the elastic force of the diaphragm resisting its deployment into the pumping chamber prevents a peripheral portion of the diaphragm body from fully contacting the pumping chamber wall.

公开(公告)号：US11666690B2

公开(公告)日：2023-06-06

申请号：US16901897

申请日：2020-06-15

Applicant: DEKA Products Limited Partnership

Inventor： Michael J. Wilt ,  Todd A. Ballantyne ,  Jason A. Demers

IPC: A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  A61M1/26 ,  G16H20/40 ,  A61M1/14 ,  A61M5/172

CPC classification number: A61M1/1601 ,  A61M1/15 ,  A61M1/1565 ,  A61M1/1566 ,  A61M1/16 ,  A61M1/1621 ,  A61M1/1635 ,  A61M1/1694 ,  A61M1/267 ,  A61M1/341 ,  A61M1/3462 ,  A61M1/3622 ,  A61M1/3626 ,  A61M1/3644 ,  A61M1/3652 ,  A61M1/3672 ,  A61M1/36225 ,  A61M1/362223 ,  A61M1/362227 ,  A61M1/362261 ,  A61M1/362265 ,  A61M1/362266 ,  A61M5/172 ,  G16H20/40 ,  A61M1/1613 ,  A61M1/1619 ,  A61M1/1696 ,  A61M1/3427 ,  A61M1/3441 ,  A61M1/3465 ,  A61M1/365 ,  A61M1/3609 ,  A61M1/3646 ,  A61M2205/12 ,  A61M2205/123 ,  A61M2205/128 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3379 ,  A61M2205/502 ,  Y10T137/87893

Abstract: Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.

公开(公告)号：US20220152286A1

公开(公告)日：2022-05-19

申请号：US17528921

申请日：2021-11-17

Applicant: DEKA Products Limited Partnership

Inventor： Michael J. Wilt ,  Jason M. Sachs

IPC: A61M1/36 ,  G01N27/07 ,  G01R27/14

Abstract: An apparatus and method are disclosed for detecting the disconnection of a vascular access device such as a needle, cannula or catheter from a blood vessel or vascular graft segment. A pair of electrodes is placed in direct contact with fluid or blood in fluid communication with the vascular segment. In one embodiment, the electrodes are incorporated into a pair of connectors connecting arterial and venous catheters to arterial and venous tubes leading to and from an extracorporeal blood flow apparatus. Wires leading from the electrodes to a detecting circuit can be incorporated into a pair of double lumen arterial and venous tubes connecting the blood flow apparatus to the blood vessel or vascular graft. The detecting circuit is configured to provide a low-voltage alternating current signal to the electrodes to measure the electrical resistance between the electrodes, minimizing both the duration and amount of current being delivered. Detection of an increase in electrical resistance between the electrodes exceeding a pre-determined threshold value may be used to indicate a possible disconnection of the vascular access device.

公开(公告)号：US11311656B2

公开(公告)日：2022-04-26

申请号：US16594181

申请日：2019-10-07

Applicant: DEKA Products Limited Partnership

Inventor： Dean Kamen ,  Jason A. Demers ,  Michael J. Wilt ,  Kevin L. Grant ,  Shannon Prescott ,  David E. Collins

IPC: A61M1/16 ,  A61M1/36 ,  A61M1/34 ,  A61M60/40 ,  A61M1/00 ,  B01D61/30 ,  B01D61/32 ,  A61M39/10

Abstract: A modular assembly for a portable hemodialysis system may include a dialysis unit, e.g., that contains suitable components for performing hemodialysis, such as a dialyzer, one or more pumps to circulate blood through the dialyzer, a source of dialysate, and one or more pumps to circulate the dialysate through the dialyzer, and a power unit having a housing that contains suitable components for providing operating power to the pumps of the dialysis unit. The power unit may be selectively connected to the dialysis unit and provide power (e.g., pneumatic power in the form of pressure and/or vacuum) to the dialysis unit for the pumps when connected to the dialysis unit, but may be incapable of providing power to the dialysis unit when disconnected from the dialysis unit. The dialysis unit and the power unit are sized and weighted to each be carried by hand by a human.

公开(公告)号：US09987407B2

公开(公告)日：2018-06-05

申请号：US14692801

申请日：2015-04-22

Applicant: DEKA Products Limited Partnership

Inventor： Kevin L. Grant ,  James D. Dale ,  Michael J. Wilt ,  Jason A. Demers ,  David E. Collins ,  Brian D. Tracey

IPC: A61M1/16 ,  A61M1/00 ,  A61M1/36 ,  B01D61/32 ,  A61M39/10 ,  A61M1/10 ,  B01D61/30

CPC classification number: A61M1/16 ,  A61M1/0082 ,  A61M1/0084 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/106 ,  A61M1/1601 ,  A61M1/1633 ,  A61M1/1639 ,  A61M1/1656 ,  A61M1/166 ,  A61M1/1668 ,  A61M1/1682 ,  A61M1/1686 ,  A61M1/1696 ,  A61M1/3607 ,  A61M1/3627 ,  A61M39/1011 ,  A61M39/105 ,  A61M2205/12 ,  A61M2205/15 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/58 ,  A61M2209/08 ,  B01D61/30 ,  B01D61/32

Abstract: A blood circuit assembly for a dialysis unit may include an organizing tray, a pair of pneumatic pumps mounted to the organizing tray for circulating blood received from a patient through a circuit including a dialyzer unit and returned to the patient, an air trap mounted to the organizing tray arranged to remove air from blood circulating in the circuit, a pair of dialyzer connections arranged to connect to the inlet and outlet of a dialyzer unit, and a pair of blood line connectors, one inlet blood line connector for receiving blood from the patient and providing blood to the pneumatic pumps and the other outlet blood line connector for returning blood to the patient.