公开(公告)号：US11298549B2

公开(公告)日：2022-04-12

申请号：US15589726

申请日：2017-05-08

Applicant: NYXOAH SA

Inventor： Adi Mashiach ,  Itzik Mashiach ,  Guy Siman

IPC: A61N1/372 ,  A61N1/375 ,  A61N1/36 ,  A61N1/04 ,  A61N1/378 ,  A61N2/00 ,  A61B5/00 ,  A61F5/56 ,  A61N1/05 ,  A61B5/389 ,  A61B5/11 ,  A61B5/113 ,  A61B17/30 ,  A61B5/01 ,  A61B7/04 ,  A61N2/02

Abstract: A medical device control unit is provided. The control unit may include at least one processing device, a circuit electrically coupled to the at least one processing device, and a flexible housing configured to contain the at least one processing device and the circuit. The flexible housing may include at least one connection portion configured to engage a connector protruding from a flexible carrier, and at least one electrical contact electrically coupled to the circuit and configured to establish an electrical connection with an exposed electrical contact on the flexible carrier when the connection portion is engaged with the at least one connection portion.

公开(公告)号：US11191970B2

公开(公告)日：2021-12-07

申请号：US15988423

申请日：2018-05-24

Applicant: NYXOAH SA

Inventor： Adi Mashiach ,  Tim Ruytjens

IPC: A61N1/378 ,  A61N1/36 ,  H04B5/00

Abstract: A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.

公开(公告)号：US20190239947A1

公开(公告)日：2019-08-08

申请号：US16282613

申请日：2019-02-22

Applicant: Nyxoah SA

Inventor： Adi Mashiach

IPC: A61B18/14 ,  A61N1/36 ,  A61N1/05

CPC classification number: A61B18/1492 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/1465 ,  A61N1/0551 ,  A61N1/36057 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/37223

Abstract: Systems and methods for hypertension control via energy delivery to one or more nerves affecting blood pressure are provided. Systems may include implantable devices configured for non-contacting neuromodulation. Implantable devices may be configured for intravascular implantation. Systems may also include external devices configured to communicated with implantable neuromodulation devices, Additional systems may include non-implantable devices for delivering modulation energy and ablation energy to one or more nerves affecting blood pressure.

公开(公告)号：US09950166B2

公开(公告)日：2018-04-24

申请号：US14307003

申请日：2014-06-17

Applicant: NYXOAH SA

Inventor： Adi Mashiach ,  Itzik Mashiach

IPC: A61N1/05 ,  A61N1/36 ,  A61N1/375 ,  A61N1/378 ,  A61N2/00 ,  A61B5/11 ,  A61B5/113 ,  A61F5/56 ,  A61N1/372 ,  A61B5/08 ,  A61B5/00 ,  A61N2/02 ,  A61B5/0488

CPC classification number: A61N1/3611 ,  A61B5/0031 ,  A61B5/0488 ,  A61B5/08 ,  A61B5/11 ,  A61B5/113 ,  A61B5/4519 ,  A61B5/4818 ,  A61B5/682 ,  A61B5/6822 ,  A61B5/6833 ,  A61B5/6876 ,  A61B2560/0219 ,  A61B2562/164 ,  A61F5/566 ,  A61N1/0514 ,  A61N1/0526 ,  A61N1/0553 ,  A61N1/36003 ,  A61N1/3601 ,  A61N1/36057 ,  A61N1/3606 ,  A61N1/36075 ,  A61N1/36117 ,  A61N1/36135 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/37223 ,  A61N1/37229 ,  A61N1/3756 ,  A61N1/3787 ,  A61N2/006 ,  A61N2/02

Abstract: An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.

公开(公告)号：US09855032B2

公开(公告)日：2018-01-02

申请号：US14059632

申请日：2013-10-22

Applicant: Nyxoah SA

Inventor： Adi Mashiach ,  Tim Ruytjens ,  Itzik Mashiach

IPC: A61N1/36 ,  A61B17/04 ,  A61N1/05 ,  A61N1/378 ,  A61N1/372 ,  H04B5/00 ,  H02J7/02 ,  A61N1/375 ,  H02J50/12

CPC classification number: A61B17/0482 ,  A61N1/0526 ,  A61N1/0548 ,  A61N1/0558 ,  A61N1/36003 ,  A61N1/3601 ,  A61N1/3605 ,  A61N1/3606 ,  A61N1/36071 ,  A61N1/36075 ,  A61N1/3611 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36132 ,  A61N1/36189 ,  A61N1/37229 ,  A61N1/375 ,  A61N1/3787 ,  H02J7/025 ,  H02J50/05 ,  H02J50/12 ,  H04B5/0031 ,  H04B5/0037 ,  H04B5/0081 ,  H04B5/0093 ,  Y10T29/49018

Abstract: Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.

公开(公告)号：US20170065822A1

公开(公告)日：2017-03-09

申请号：US15355981

申请日：2016-11-18

Applicant: NYXOAH SA

Inventor： Adi Mashiach ,  Tim Ruytjens

IPC: A61N1/378 ,  H04B5/00 ,  A61N1/36

CPC classification number: A61N1/3787 ,  A61N1/36075 ,  A61N1/3611 ,  H04B5/0037 ,  H04B5/0093

Abstract: A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.

Abstract translation: 用于将动力从受试者外部的位置输送到对象内的位置的装置可以包括柔性载体和在载体的第一侧上的粘合剂。 导电材料的线圈可以与柔性载体相关联。 机械连接器可以与载体相对的粘合剂相关联，其中机械连接器构造成保持壳体并允许壳体相对于柔性载体旋转。 至少一个电气部分可以以允许在壳体旋转时在柔性载体和壳体之间保持电连接的方式与载体相关联。

公开(公告)号：US11730469B2

公开(公告)日：2023-08-22

申请号：US16911667

申请日：2020-06-25

Applicant: NYXOAH SA

Inventor： Adi Mashiach ,  Itzik Mashiach ,  Guy Siman

IPC: A61B17/04 ,  H04B5/00 ,  A61B17/30 ,  A61N1/378 ,  A61N1/05 ,  A61N1/36 ,  A61N1/372 ,  A61B5/24 ,  A61B5/389

CPC classification number: A61B17/0491 ,  A61B5/24 ,  A61B5/389 ,  A61B17/0482 ,  A61B17/30 ,  A61N1/0526 ,  A61N1/0558 ,  A61N1/3601 ,  A61N1/3611 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36189 ,  A61N1/3787 ,  A61N1/37229 ,  H04B5/0037 ,  H04B5/0043 ,  H04B5/0093 ,  H04B5/0031 ,  H04B5/0081

Abstract: An implant unit delivery tool is provided. The implant delivery tool may include a body, a holder disposed at a distal end of the body and adapted to hold an implant unit, and an implant activator associated with the body, the implant activator configured to receive power from a power source. The implant activator may be configured to selectively and wirelessly transfer power from the power source to the implant unit during implantation of the implant unit into the body of a subject to cause modulation of at least one nerve in the body of the subject, and determine a degree of nerve modulation response resulting from the selective and wireless transfer of power from the power source to the implant unit claims.

公开(公告)号：US11478240B2

公开(公告)日：2022-10-25

申请号：US16297974

申请日：2019-03-11

Applicant: NYXOAH SA

Inventor： Adi Mashiach

IPC: A61B17/04 ,  A61N1/36 ,  A61N1/05 ,  A61N1/378 ,  A61N1/372 ,  H04B5/00 ,  H02J50/12 ,  H02J7/02 ,  H02J50/05

Abstract: A delivery system is disclosed having an implant retainer configured to releasably hold an implant unit and maintain the implant unit in a fixation location relative to target tissue in a subject's body during an implantation procedure. A first suture guide portion may be disposed on a first side of the implant retainer and configured to guide a suture needle during the implantation procedure. A second suture guide portion may be disposed on a second side of the implant retainer, opposite the first side, and configured to guide the suture needle after the suture needle exits the first suture guide portion.

公开(公告)号：US10751537B2

公开(公告)日：2020-08-25

申请号：US15938100

申请日：2018-03-28

Applicant: NYXOAH SA

Inventor： Adi Mashiach ,  Itzik Mashiach

IPC: A61N1/36 ,  A61N1/05 ,  A61N1/375 ,  A61N1/378 ,  A61N2/00 ,  A61B5/00 ,  A61B5/11 ,  A61B5/113 ,  A61F5/56 ,  A61N1/372 ,  A61B5/08 ,  A61N2/02 ,  A61B5/0488

Abstract: An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.

公开(公告)号：US20180325509A1

公开(公告)日：2018-11-15

申请号：US16044668

申请日：2018-07-25

Applicant: NYXOAH SA

Inventor： Adi Mashiach ,  Itzik Mashiach ,  Guy Siman

IPC: A61B17/04 ,  A61B17/30 ,  A61B5/04 ,  H04B5/00 ,  A61N1/36 ,  A61N1/372 ,  A61N1/05 ,  A61N1/378 ,  A61B5/0488

CPC classification number: A61B17/0491 ,  A61B5/04001 ,  A61B5/0488 ,  A61B17/0482 ,  A61B17/30 ,  A61N1/0526 ,  A61N1/0558 ,  A61N1/3601 ,  A61N1/36071 ,  A61N1/3611 ,  A61N1/36125 ,  A61N1/36189 ,  A61N1/37229 ,  A61N1/3787 ,  H04B5/0031 ,  H04B5/0037 ,  H04B5/0043 ,  H04B5/0081 ,  H04B5/0093

Abstract: An implant unit delivery tool is provided. The implant delivery tool may include a body, a holder disposed at a distal end of the body and adapted to hold an implant unit, and an implant activator associated with the body, the implant activator configured to receive power from a power source. The implant activator may be configured to selectively and wirelessly transfer power from the power source to the implant unit during implantation of the implant unit into the body of a subject to cause modulation of at least one nerve in the body of the subject, and determine a degree of nerve modulation response resulting from the selective and wireless transfer of power from the power source to the implant unit claims.