公开(公告)号：US20120115897A1

公开(公告)日：2012-05-10

申请号：US13320101

申请日：2009-12-24

申请人： Luhong Tang ,  Ajuan Dai ,  Ze Wang ,  Yang Sun ,  Xinning Liu ,  Lingyan Xu ,  Xin Fang ,  Shuang Qiu ,  Yaqing Cao ,  Xiaomin Xu ,  Ruixia Jiang ,  Chao Wu

发明人： Luhong Tang ,  Ajuan Dai ,  Ze Wang ,  Yang Sun ,  Xinning Liu ,  Lingyan Xu ,  Xin Fang ,  Shuang Qiu ,  Yaqing Cao ,  Xiaomin Xu ,  Ruixia Jiang ,  Chao Wu

IPC分类号： A61K31/436 ,  C07D491/052 ,  C12P17/04 ,  C12P17/18 ,  A61K31/375 ,  A61K31/407 ,  A61P29/00 ,  A61P19/02 ,  A61P25/00 ,  A61P25/28 ,  A61P35/00 ,  A61P15/00 ,  A61P11/00 ,  A61P9/00 ,  C07D307/62

CPC分类号： C07D307/62 ,  C07D405/12 ,  C07D491/04 ,  C07D491/052 ,  C12P17/04 ,  C12P17/16 ,  C12P17/188 ,  C12Y301/01003

摘要： The present invention designs and synthesizes the ascorbyl ester derivatives of the aryl (ethanoic) propanoic acid non-steroidal anti-inflammatory medicaments, such as ibuprofen, ketoprofen and naproxen, and addition salt of the derivatives with pharmaceutical acid or pharmaceutical alkaline. The non-steroidal anti-inflammatory medicament which takes the ibuprofen as the representative is a common antipyretic analgesic medicament. The invention has remarkable antipyretic and analgesic effects and good safety except for anti-inflammatory effect, thus being not only suitable for adults, but also suitable for the elderly people, infants and children. The aryl (ethanoic) propanoic acid ascorbyl ester can be converted into ascorbyl ester derivatives and the addition salts of the derivatives with pharmaceutical acid or pharmaceutical alkaline, which can improve the water solubility thereof, facilitate intravenously administration, reduce the onset time, improve the bioavailability, reduce the stimulation effect to gastrointestinal tract, and enhance the penetrating capacity to hemato encephalic barrier, and can be used as a novel medicament to be applied for antiphlogistic, antipyresis, analgesia, treatment of arthritis, dysmenorrheal, multiple sclerosis, pneumonia cystic fibrosis and patent ductus arteriosus of premature infants, and prevention and treatment of cerebral apoplexy, hypoxic-ischemic brain damage, senile dementia and certain cancers.

摘要翻译： 本发明设计和合成芳基（乙酸）丙酸非甾体抗炎药物如布洛芬，酮洛芬和萘普生的抗坏血酸酯衍生物，以及衍生物与药物酸或药物碱的加成盐。 以布洛芬为代表的非甾体抗炎药是常见的解热止痛药。 本发明除抗炎作用外，具有明显的解热镇痛作用，安全性好，不仅适用于成人，而且适用于老年人，婴儿和儿童。 芳基（乙酸）丙酸抗坏血酸酯可以转化为抗坏血酸酯衍生物，并且衍生物的加成盐与药物酸或药物碱性可以改善其水溶性，有助于静脉内施用，减少发病时间，提高生物利用度 降低对胃肠道的刺激作用，增强血液渗透屏障的穿透能力，可用作新型药物，用于消炎止痛，止痛，止痛，治疗关节炎，痛经，多发性硬化，肺炎囊性纤维化，以及 早产儿动脉导管未闭，预防和治疗脑中风，缺氧缺血性脑损伤，老年性痴呆和某些癌症。

公开(公告)号：US08703975B2

公开(公告)日：2014-04-22

申请号：US13320101

申请日：2009-12-24

申请人： Luhong Tang ,  Ajuan Dai ,  Ze Wang ,  Yang Sun ,  Xinning Liu ,  Lingyan Xu ,  Xin Fang ,  Shuang Qiu ,  Yaqing Cao ,  Xiaomin Xu ,  Ruixia Jiang ,  Chao Wu

发明人： Luhong Tang ,  Ajuan Dai ,  Ze Wang ,  Yang Sun ,  Xinning Liu ,  Lingyan Xu ,  Xin Fang ,  Shuang Qiu ,  Yaqing Cao ,  Xiaomin Xu ,  Ruixia Jiang ,  Chao Wu

IPC分类号： C07D307/62

CPC分类号： C07D307/62 ,  C07D405/12 ,  C07D491/04 ,  C07D491/052 ,  C12P17/04 ,  C12P17/16 ,  C12P17/188 ,  C12Y301/01003

摘要： The present invention designs and synthesizes the ascorbyl ester derivatives of the aryl (ethanoic) propanoic acid non-steroidal anti-inflammatory medicaments, such as ibuprofen, ketoprofen and naproxen, and addition salt of the derivatives with pharmaceutical acid or pharmaceutical alkaline. The non-steroidal anti-inflammatory medicament which takes the ibuprofen as the representative is a common antipyretic analgesic medicament. The invention has remarkable antipyretic and analgesic effects and good safety except for anti-inflammatory effect, thus being not only suitable for adults, but also suitable for the elderly people, infants and children. The aryl (ethanoic) propanoic acid ascorbyl ester can be converted into ascorbyl ester derivatives and the addition salts of the derivatives with pharmaceutical acid or pharmaceutical alkaline, which can improve the water solubility thereof, facilitate intravenously administration, reduce the onset time, improve the bioavailability, reduce the stimulation effect to gastrointestinal tract, and enhance the penetrating capacity to hemato encephalic barrier, and can be used as a novel medicament to be applied for antiphlogistic, antipyresis, analgesia, treatment of arthritis, dysmenorrheal, multiple sclerosis, pneumonia cystic fibrosis and patent ductus arteriosus of premature infants, and prevention and treatment of cerebral apoplexy, hypoxic-ischemic brain damage, senile dementia and certain cancers.

摘要翻译： 本发明设计和合成芳基（乙酸）丙酸非甾体抗炎药物如布洛芬，酮洛芬和萘普生的抗坏血酸酯衍生物，以及衍生物与药物酸或药物碱的加成盐。 以布洛芬为代表的非甾体抗炎药是常见的解热止痛药。 本发明除抗炎作用外，具有明显的解热镇痛作用，安全性好，不仅适用于成人，而且适用于老年人，婴儿和儿童。 芳基（乙酸）丙酸抗坏血酸酯可以转化为抗坏血酸酯衍生物，并且衍生物的加成盐与药物酸或药物碱性可以改善其水溶性，有助于静脉内施用，减少发病时间，提高生物利用度 降低对胃肠道的刺激作用，增强血液渗透屏障的穿透能力，可用作新型药物，用于消炎止痛，止痛，止痛，治疗关节炎，痛经，多发性硬化，肺炎囊性纤维化，以及 早产儿动脉导管未闭，预防和治疗脑中风，缺氧缺血性脑损伤，老年性痴呆和某些癌症。

公开(公告)号：US09647808B2

公开(公告)日：2017-05-09

申请号：US14402708

申请日：2012-06-11

申请人： Chao Wu ,  Peter Skov ,  Li Zhang ,  Timo Erkki Lunttila

发明人： Chao Wu ,  Peter Skov ,  Li Zhang ,  Timo Erkki Lunttila

IPC分类号： H04L5/00 ,  H04W88/08

CPC分类号： H04L5/0039 ,  H04L5/0005 ,  H04L5/001 ,  H04L5/0023 ,  H04L5/0037 ,  H04L5/0064 ,  H04W88/08

摘要： Definition of a combined bandwidth is disclosed. Bandwidths for components of a combined bandwidth can be defined by selecting configurations for the bandwidths from a group of available bandwidth configurations. The bandwidths are combined to define a contiguously combined bandwidth in a resource block unit. At least one set of coefficients corresponding to the available bandwidth configurations are used. The contiguously combined bandwidth shall not exceeds a predefined maximum bandwidth. A transmission bandwidth can be defined. A channel bandwidth can be defined based on the defined transmission bandwidth.

公开(公告)号：US20110101856A1

公开(公告)日：2011-05-05

申请号：US12916913

申请日：2010-11-01

申请人： Mark E. Thompson ,  Chao Wu ,  Hsiao-Fan Chen

发明人： Mark E. Thompson ,  Chao Wu ,  Hsiao-Fan Chen

IPC分类号： H01J1/62 ,  C07F15/00 ,  B05D5/06

CPC分类号： H01L51/0085 ,  C07F15/0033 ,  C09K11/06 ,  C09K2211/1029 ,  C09K2211/185 ,  H01L51/0037 ,  H01L51/0059 ,  H01L51/006 ,  H01L51/008 ,  H01L51/5012 ,  H05B33/14

摘要： Organometallic soft salt compounds are provided. In particular, the compounds comprise mononuclear Ir-based soft salts. The compounds may be used in organic light emitting diodes (OLED) and light emitting cells (LEC).

摘要翻译： 提供有机金属软盐化合物。 特别地，这些化合物包括单核Ir-基软盐。 该化合物可用于有机发光二极管（OLED）和发光单元（LEC）。

公开(公告)号：US20050208638A1

公开(公告)日：2005-09-22

申请号：US10806053

申请日：2004-03-22

申请人： Chao Wu ,  Tedd Struckmeyer

发明人： Chao Wu ,  Tedd Struckmeyer

IPC分类号： A23C21/00 ,  A23J1/20 ,  A23J3/08 ,  A23L1/305 ,  A61K8/64 ,  A61K8/98 ,  A61K35/20 ,  A61Q11/00 ,  A61Q19/00 ,  C07K14/495 ,  C07K14/65 ,  C12N5/00 ,  C12N9/08

CPC分类号： A61Q19/00 ,  A23C21/00 ,  A23J1/205 ,  A23J3/08 ,  A23L33/19 ,  A61K8/64 ,  A61K8/986 ,  A61K35/20 ,  A61Q11/00 ,  C12N5/0018

摘要： The present invention involves the discovery that various liquid (whey) streams drained or expelled from cheese curd after salt addition in the preparation of cheese contain enriched levels of bioactive proteins such as lactoferrin, lactoperoxidase, immunoglobulins, and growth factors. According to the invention, these proteins may be further enriched through manipulation of the cheese salting process as described herein. The methods of the invention may be used to produce various whey products with enriched levels of all the above bioactive proteins present and, through manipulation of salting conditions, to enrich these proteins selectively.

摘要翻译： 本发明涉及发现，在酪乳制品中加入盐后，从干酪凝乳中排出或排出的各种液体（乳清）流含有富含水平的生物活性蛋白如乳铁蛋白，乳过氧化物酶，免疫球蛋白和生长因子。 根据本发明，这些蛋白质可以通过如本文所述的奶酪盐化过程的操作进一步富集。 本发明的方法可用于生产具有所有上述生物活性蛋白质富集水平的各种乳清产品，并且通过操作盐析条件来选择性富集这些蛋白质。

公开(公告)号：US06312755B1

公开(公告)日：2001-11-06

申请号：US09356124

申请日：1999-07-16

申请人： Chao Wu

发明人： Chao Wu

IPC分类号： A23J100

CPC分类号： A23C9/1425 ,  A23J1/205 ,  A23V2002/00 ,  A23V2250/54242 ,  A23V2300/34

摘要： A method of making an &agr;-lactalbumin enriched whey protein product is described. The method involves the treatment of a whey protein product with an acid to lower the pH of the whey protein product to 4.0 or below. This pH-lowering step allows the &agr;-lactalbumin molecules to be concentrated more efficiently.

摘要翻译： 描述了制备富含α-乳白蛋白的乳清蛋白产物的方法。 该方法涉及用酸处理乳清蛋白产物以将乳清蛋白产物的pH降至4.0或更低。 该pH降低步骤可以更有效地浓缩α-乳白蛋白分子。

公开(公告)号：US08389039B2

公开(公告)日：2013-03-05

申请号：US12366343

申请日：2009-02-05

申请人： Chao Wu ,  Tedd Struckmeyer

发明人： Chao Wu ,  Tedd Struckmeyer

IPC分类号： A23C21/00

CPC分类号： A61Q19/00 ,  A23C21/00 ,  A23J1/205 ,  A23J3/08 ,  A23L33/19 ,  A61K8/64 ,  A61K8/986 ,  A61K35/20 ,  A61Q11/00 ,  C12N5/0018

摘要： The present invention involves the discovery that various liquid (whey) streams drained or expelled from cheese curd after salt addition in the preparation of cheese contain enriched levels of bioactive proteins such as lactoferrin, lactoperoxidase, immunoglobulins, and growth factors. According to the invention, these proteins may be further enriched through manipulation of the cheese salting process as described herein. The methods of the invention may be used to produce various whey products with enriched levels of all the above bioactive proteins present and, through manipulation of salting conditions, to enrich these proteins selectively.

摘要翻译： 本发明涉及发现，在酪乳制品中加入盐后，从干酪凝乳中排出或排出的各种液体（乳清）流含有富含水平的生物活性蛋白如乳铁蛋白，乳过氧化物酶，免疫球蛋白和生长因子。 根据本发明，这些蛋白质可以通过如本文所述的奶酪盐化过程的操作进一步富集。 本发明的方法可用于生产具有所有上述生物活性蛋白质富集水平的各种乳清产品，并且通过操作盐析条件来选择性富集这些蛋白质。

公开(公告)号：US20060164884A1

公开(公告)日：2006-07-27

申请号：US11043854

申请日：2005-01-25

申请人： Chao Wu

发明人： Chao Wu

IPC分类号： G11C16/04

CPC分类号： G11C11/5628 ,  G11C11/5642 ,  G11C16/3454 ,  G11C16/3459 ,  G11C2211/5621

摘要： Pre-program verify levels for a multilevel read-only memory cell are generated dynamically. A determination takes into account a program verify level, an over-program budget, and a second-bit effect budget to generate pre-program verify levels. The generated pre-program verify levels mitigate issues of over-programming, hard-to-program, and second-bit effect.

摘要翻译： 动态生成多级只读存储单元的预编程验证级别。 确定考虑到程序验证级别，过程计划预算和第二位效应预算，以生成预编程验证级别。 生成的预编程验证级别可以减轻过度编程，难以编程和第二位影响的问题。

公开(公告)号：US20060078266A1

公开(公告)日：2006-04-13

申请号：US11188183

申请日：2005-07-22

申请人： Chao Wu ,  Yuan Wang ,  Jui Pan

发明人： Chao Wu ,  Yuan Wang ,  Jui Pan

IPC分类号： G02B6/10

CPC分类号： G02B27/0927 ,  G02B27/0994 ,  H04N9/315

摘要： An optical engine for an image projector comprises a light source, a taper rod, at least one light condenser, a prism module, a Digital Micromirror Device (DMD) and a projection lens set. One end of the taper rod is adjacent to the light source. Light generated by the light source is guided by the taper rod following a light path. The taper rod has increasing sizes of cross-sections along the light path, so as to decrease the dispersion angle of light, make the light more uniform, and increase the brightness of light. The prism module includes a first prism having a right triangle cross-section and a second prism having a wedge cross-section. The prism module receives the light from the condenser, passes the light toward the DMD, receives the light reflected by the DMD, and then passes the reflected light toward the projection lens set. The projection lens set projects the light on an external projection plane.

摘要翻译： 用于图像投影仪的光学引擎包括光源，锥形杆，至少一个光聚光器，棱镜模块，数字微镜器件（DMD）和投影透镜组。 锥形杆的一端与光源相邻。 由光源产生的光由沿着光路的锥形杆引导。 锥形杆具有沿着光路的横截面增大的尺寸，以减小光的色散角，使光线更均匀，并增加光的亮度。 棱镜模块包括具有直角三角形横截面的第一棱镜和具有楔形横截面的第二棱镜。 棱镜模块接收来自聚光器的光，将光朝向DMD传递，接收由DMD反射的光，然后使反射光朝向投影透镜组。 投影透镜组将光投射到外部投影平面上。

公开(公告)号：US20060077353A1

公开(公告)日：2006-04-13

申请号：US11187481

申请日：2005-07-22

申请人： Chao Wu

发明人： Chao Wu

IPC分类号： G03B21/16

CPC分类号： H04N9/3144 ,  G03B21/12 ,  G03B21/16

摘要： An image projector having a LED light source comprises: an optical engine using the LED as the light source, a PCB module, a heat sink module and a main frame. The printed circuit board (PCB) module further comprises: a first circuit board, a second circuit board, at least one I/O interface for connecting an external device, at least one card reader for connecting an external memory card, and a control unit for processing the image data received from the I/O interface or card reader and projecting the image by using the optical engine. The first circuit board and second circuit board are furnished in an overlap and parallel manner to decrease the space consumption. The heat sink module comprises a fan, an air inlet and an air outlet, which substantially forms a heat dissipating passage from the air inlet through the fan toward the air outlet. The LED and control unit are located in the heat dissipating passage for increasing better heat dissipation effect.

摘要翻译： 具有LED光源的图像投影仪包括：使用LED作为光源的光学引擎，PCB模块，散热模块和主框架。 印刷电路板（PCB）模块还包括：第一电路板，第二电路板，用于连接外部设备的至少一个I / O接口，用于连接外部存储卡的至少一个读卡器和控制单元 用于处理从I / O接口或读卡器接收的图像数据，并通过使用光学引擎投影图像。 第一电路板和第二电路板以重叠和平行的方式设置以减少空间消耗。 散热器模块包括风扇，空气入口和空气出口，其基本形成从空气入口通过风扇朝向空气出口的散热通道。 LED和控制单元位于散热通道中，以提高散热效果。