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公开(公告)号：US20120157717A1
公开(公告)日：2012-06-21
申请号：US13233489
申请日：2011-09-15
Applicant: Mathew A. RUDE , Andreas W. SCHIRMER
Inventor： Mathew A. RUDE , Andreas W. SCHIRMER
CPC classification number: C12Y201/03001 , C12N9/0006 , C12N9/1018 , C12N9/1029 , C12N9/1217 , C12N9/16 , C12N9/18 , C12N9/88 , C12N9/90 , C12P7/6409 , C12Y101/01003 , C12Y101/01085 , C12Y203/01041 , C12Y207/02004 , C12Y301/02001 , C12Y401/01041 , C12Y401/03022 , C12Y402/01033 , C12Y402/03001 , C12Y403/01019 , C12Y504/99002
Abstract: Compositions and methods for producing hydrocarbons using recombinant cells are described herein. Also described herein are recombinant cells, recombinant cell cultures and methods for producing linear alkyl benzenes (LABs) using hydrocarbons produced by such recombinant cell cultures.
Abstract translation: 本文描述了使用重组细胞产生烃的组合物和方法。 本文还描述了使用由这种重组细胞培养物产生的烃的重组细胞，重组细胞培养物和用于生产线性烷基苯（LAB）的方法。
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公开(公告)号：US20120301947A1
公开(公告)日：2012-11-29
申请号：US13576720
申请日：2011-02-10
Applicant: Ron Milo , Arren Bar-Even , Elad Noor
Inventor： Ron Milo , Arren Bar-Even , Elad Noor
CPC classification number: C12N9/93 , C12N9/0006 , C12N9/0008 , C12N9/1018 , C12N9/1205 , C12N9/13 , C12N9/18 , C12N9/88 , C12N9/90 , C12N15/70 , C12N15/8245 , C12N15/8247 , C12N15/8269 , C12P7/40 , C12P7/42 , C12P7/46 , C12P11/00 , C12Y101/01059 , C12Y102/01018 , C12Y201/03001 , C12Y208/03001 , C12Y401/01031 , C12Y402/01017 , C12Y402/01054 , C12Y604/01001 , C12Y604/01002 , G06F19/12 , Y02P20/52
Abstract: A system for carbon fixation is provided. The system comprises enzymes which catalyze reactions of a carbon fixation pathway, wherein at least one of the reactions of the carbon fixation pathway is a carboxylation reaction, wherein products of the reactions of the carbon fixation pathway comprise oxaloacetate and malonyl-CoA, wherein an enzyme which performs the carboxylation reaction is selected from the group consisting of phophoenolpyruvate (PEP) carboxlase, pyruvate carboxylase and acetyl-CoA carboxylase and wherein an export product of the carbon fixation pathway is glyoxylate. Additional carbon fixation pathways are also provided and methods of generating same.
Abstract translation: 提供了一种用于碳固定的系统。 该系统包括催化碳固定通道的反应的酶，其中碳固定通路的至少一个反应是羧化反应，其中碳固定路径的反应产物包括草酰乙酸酯和丙二酰辅酶A，其中酶 进行羧化反应的选自苯丙醇丙酮酸（PEP）羧基酶，丙酮酸羧化酶和乙酰辅酶A羧化酶，其中碳固定路径的出口产物是乙醛酸盐。 还提供了另外的碳固定路径和产生它们的方法。
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公开(公告)号：US20160298103A1
公开(公告)日：2016-10-13
申请号：US15189021
申请日：2016-06-22
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Ron MILO , Arren BAR-EVEN , Elad NOOR
CPC classification number: C12N9/93 , C12N9/0006 , C12N9/0008 , C12N9/1018 , C12N9/1205 , C12N9/13 , C12N9/18 , C12N9/88 , C12N9/90 , C12N15/70 , C12N15/8245 , C12N15/8247 , C12N15/8269 , C12P7/40 , C12P7/42 , C12P7/46 , C12P11/00 , C12Y101/01059 , C12Y102/01018 , C12Y201/03001 , C12Y208/03001 , C12Y401/01031 , C12Y402/01017 , C12Y402/01054 , C12Y604/01001 , C12Y604/01002 , G06F19/12 , Y02P20/52
Abstract: A system for carbon fixation is provided. The system comprises enzymes which catalyze reactions of a carbon fixation pathway, wherein at least one of the reactions of the carbon fixation pathway is a carboxylation reaction, wherein products of the reactions of the carbon fixation pathway comprise oxaloacetate and malonyl-CoA, wherein an enzyme which performs the carboxylation reaction is selected from the group consisting of phophoenolpyruvate (PEP) carboxlase, pyruvate carboxylase and acetyl-CoA carboxylase and wherein an export product of the carbon fixation pathway is glyoxylate. Additional carbon fixation pathways are also provided and methods of generating same.
Abstract translation: 提供了一种用于碳固定的系统。 该系统包括催化碳固定通道的反应的酶，其中碳固定通路的至少一个反应是羧化反应，其中碳固定路径的反应产物包括草酰乙酸酯和丙二酰辅酶A，其中酶 进行羧化反应的选自苯丙醇丙酮酸（PEP）羧基酶，丙酮酸羧化酶和乙酰辅酶A羧化酶，其中碳固定路径的出口产物是乙醛酸盐。 还提供了另外的碳固定路径和产生它们的方法。
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4.发明授权Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene 失效通过发酵制备L-氨基酸的方法和编码accDA基因的核苷酸序列公开(公告)号：US06808914B2
公开(公告)日：2004-10-26
申请号：US10024370
申请日：2001-12-21
Applicant: Yvonne Tilg , Bernhard Eikmanns , Lothar Eggeling , Hermann Sahm , Bettina Möckel
Inventor： Yvonne Tilg , Bernhard Eikmanns , Lothar Eggeling , Hermann Sahm , Bettina Möckel
IPC: C12N988
CPC classification number: C12Y201/03001 , C12N9/1018 , C12P13/08
Abstract: The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified.
Abstract translation: 本发明涉及通过使用其中accDA基因被扩增的棒杆菌发酵来编码accDA基因的核苷酸序列和用于制备L-氨基酸，特别是L-赖氨酸的方法。
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5.发明授权Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene 失效通过发酵制备L-氨基酸的方法和编码accDA基因的核苷酸序列公开(公告)号：US06361986B1
公开(公告)日：2002-03-26
申请号：US09362899
申请日：1999-07-29
Applicant: Yvonne Tilg , Bernd Eikmanns , Lothar Eggeling , Hermann Sahm , Bettina Möckel
Inventor： Yvonne Tilg , Bernd Eikmanns , Lothar Eggeling , Hermann Sahm , Bettina Möckel
IPC: C12N900
CPC classification number: C12Y201/03001 , C12N9/1018 , C12P13/08
Abstract: The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the accDA gene is amplified.
Abstract translation: 本发明涉及通过使用其中accDA基因被扩增的棒杆菌发酵来编码accDA基因的核苷酸序列和用于制备L-氨基酸，特别是L-赖氨酸的方法。
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Patent Agency Ranking
公开(公告)号：US10077437B2
公开(公告)日：2018-09-18
申请号：US15189021
申请日：2016-06-22
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Ron Milo , Arren Bar-Even , Elad Noor
IPC: C12N9/00 , C12N15/82 , C12N9/04 , C12N9/02 , C12N9/12 , C12N9/10 , C12N9/18 , C12N9/88 , C12N9/90 , C12P7/40 , C12N15/70 , C12P7/42 , C12P7/46 , C12P11/00 , G06F19/12
CPC classification number: C12N9/93 , C12N9/0006 , C12N9/0008 , C12N9/1018 , C12N9/1205 , C12N9/13 , C12N9/18 , C12N9/88 , C12N9/90 , C12N15/70 , C12N15/8245 , C12N15/8247 , C12N15/8269 , C12P7/40 , C12P7/42 , C12P7/46 , C12P11/00 , C12Y101/01059 , C12Y102/01018 , C12Y201/03001 , C12Y208/03001 , C12Y401/01031 , C12Y402/01017 , C12Y402/01054 , C12Y604/01001 , C12Y604/01002 , G16B5/00 , Y02P20/52
Abstract: A system for carbon fixation is provided. The system comprises enzymes which catalyze reactions of a carbon fixation pathway, wherein at least one of the reactions of the carbon fixation pathway is a carboxylation reaction, wherein products of the reactions of the carbon fixation pathway comprise oxaloacetate and malonyl-CoA, wherein an enzyme which performs the carboxylation reaction is selected from the group consisting of phophoenolpyruvate (PEP) carboxlase, pyruvate carboxylase and acetyl-CoA carboxylase and wherein an export product of the carbon fixation pathway is glyoxylate. Additional carbon fixation pathways are also provided and methods of generating same.
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公开(公告)号：US09410131B2
公开(公告)日：2016-08-09
申请号：US13576720
申请日：2011-02-10
Applicant: Ron Milo , Arren Bar-Even , Elad Noor
Inventor： Ron Milo , Arren Bar-Even , Elad Noor
IPC: C12N9/04 , C12N15/82 , C12N9/02 , C12N9/12 , C12N9/10 , C12N9/18 , C12N9/88 , C12N9/90 , C12N9/00 , C12P7/40 , G06F19/12
CPC classification number: C12N9/93 , C12N9/0006 , C12N9/0008 , C12N9/1018 , C12N9/1205 , C12N9/13 , C12N9/18 , C12N9/88 , C12N9/90 , C12N15/70 , C12N15/8245 , C12N15/8247 , C12N15/8269 , C12P7/40 , C12P7/42 , C12P7/46 , C12P11/00 , C12Y101/01059 , C12Y102/01018 , C12Y201/03001 , C12Y208/03001 , C12Y401/01031 , C12Y402/01017 , C12Y402/01054 , C12Y604/01001 , C12Y604/01002 , G06F19/12 , Y02P20/52
Abstract: A system for carbon fixation is provided. The system comprises enzymes which catalyze reactions of a carbon fixation pathway, wherein at least one of the reactions of the carbon fixation pathway is a carboxylation reaction, wherein products of the reactions of the carbon fixation pathway comprise oxaloacetate and malonyl-CoA, wherein an enzyme which performs the carboxylation reaction is selected from the group consisting of phophoenolpyruvate (PEP) carboxlase, pyruvate carboxylase and acetyl-CoA carboxylase and wherein an export product of the carbon fixation pathway is glyoxylate. Additional carbon fixation pathways are also provided and methods of generating same.
Abstract translation: 提供了一种用于碳固定的系统。 该系统包括催化碳固定通道的反应的酶，其中碳固定通路的至少一个反应是羧化反应，其中碳固定路径的反应产物包含草酰乙酸和丙二酰辅酶A，其中酶 进行羧化反应的选自苯丙醇丙酮酸（PEP）羧基酶，丙酮酸羧化酶和乙酰辅酶A羧化酶，其中碳固定路径的出口产物是乙醛酸盐。 还提供了另外的碳固定路径和产生它们的方法。
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8.发明授权Production of odd chain fatty acid derivatives in recombinant microbial cells 有权在重组微生物细胞中生产奇链脂肪酸衍生物公开(公告)号：US08372610B2
公开(公告)日：2013-02-12
申请号：US13232927
申请日：2011-09-14
Applicant: Grace J. Lee , John R. Haliburton , Zhihao Hu , Andreas W. Schirmer
Inventor： Grace J. Lee , John R. Haliburton , Zhihao Hu , Andreas W. Schirmer
CPC classification number: C12P7/6409 , C07C53/126 , C07C57/03 , C12N9/0006 , C12N9/1018 , C12N9/1029 , C12N9/1217 , C12N9/16 , C12N9/18 , C12N9/88 , C12N9/90 , C12Y101/01003 , C12Y101/01085 , C12Y201/03001 , C12Y203/01041 , C12Y207/02004 , C12Y301/02001 , C12Y401/01041 , C12Y401/03022 , C12Y402/01033 , C12Y402/03001 , C12Y403/01019 , C12Y504/99002
Abstract: Recombinant microbial cells are provided which have been engineered to produce fatty acid derivatives having linear chains containing an odd number of carbon atoms by the fatty acid biosynthetic pathway. Also provided are methods of making odd chain fatty acid derivatives using the recombinant microbial cells, and compositions comprising odd chain fatty acid derivatives produced by such methods.
Abstract translation: 提供了重组微生物细胞，其已被工程化以通过脂肪酸生物合成途径产生具有含有奇数个碳原子的直链的脂肪酸衍生物。 还提供了使用重组微生物细胞制备奇数链脂肪酸衍生物的方法，以及包含通过这些方法产生的奇数链脂肪酸衍生物的组合物。
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9.发明申请PRODUCTION OF ODD CHAIN FATTY ACID DERIVATIVES IN RECOMBINANT MICROBIAL CELLS 审中-公开在重组微生物细胞中生产链状脂肪酸衍生物公开(公告)号：US20150167033A1
公开(公告)日：2015-06-18
申请号：US14344658
申请日：2012-03-08
Applicant: Grace J. Lee , John R. Haliburton , Zhihao Hu , Andreas W. Schirmer
Inventor： Grace J. Lee , John R. Haliburton , Zhihao Hu , Andreas W. Schirmer
IPC: C12P7/64 , C07C57/03 , C07C53/126
CPC classification number: C12P7/6409 , C07C53/126 , C07C57/03 , C12N9/0006 , C12N9/1018 , C12N9/1029 , C12N9/1217 , C12N9/16 , C12N9/18 , C12N9/88 , C12N9/90 , C12Y101/01003 , C12Y101/01085 , C12Y201/03001 , C12Y203/01041 , C12Y207/02004 , C12Y301/02001 , C12Y401/01041 , C12Y401/03022 , C12Y402/01033 , C12Y402/03001 , C12Y403/01019 , C12Y504/99002
Abstract: Recombinant microbial cells are provided which have been engineered to produce fatty acid derivatives having linear chains containing an odd number of carbon atoms by the fatty acid biosynthetic pathway. Also provided are methods of making odd chain fatty acid derivatives using the recombinant microbial cells, and compositions comprising odd chain fatty acid derivatives produced by such methods.
Abstract translation: 提供了重组微生物细胞，其已被工程化以通过脂肪酸生物合成途径产生具有含有奇数个碳原子的直链的脂肪酸衍生物。 还提供了使用重组微生物细胞制备奇数链脂肪酸衍生物的方法，以及包含通过这些方法产生的奇数链脂肪酸衍生物的组合物。
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10.发明申请PRODUCTION OF ODD CHAIN FATTY ACID DERIVATIVES IN RECOMBINANT MICROBIAL CELLS 有权在重组微生物细胞中生产链状脂肪酸衍生物公开(公告)号：US20120070868A1
公开(公告)日：2012-03-22
申请号：US13232927
申请日：2011-09-14
Applicant: Grace J. Lee , John R. Haliburton , Zhihao Hu , Andreas W. Schirmer
Inventor： Grace J. Lee , John R. Haliburton , Zhihao Hu , Andreas W. Schirmer
IPC: C07C53/126 , C12P7/04 , C12P5/02 , C07C31/02 , C12N1/21 , C12N15/63 , C12N1/19 , C12N1/13 , C12N5/10 , C07C57/03 , C07C9/00 , C12P7/64 , C12N1/15
CPC classification number: C12P7/6409 , C07C53/126 , C07C57/03 , C12N9/0006 , C12N9/1018 , C12N9/1029 , C12N9/1217 , C12N9/16 , C12N9/18 , C12N9/88 , C12N9/90 , C12Y101/01003 , C12Y101/01085 , C12Y201/03001 , C12Y203/01041 , C12Y207/02004 , C12Y301/02001 , C12Y401/01041 , C12Y401/03022 , C12Y402/01033 , C12Y402/03001 , C12Y403/01019 , C12Y504/99002
Abstract: Recombinant microbial cells are provided which have been engineered to produce fatty acid derivatives having linear chains containing an odd number of carbon atoms by the fatty acid biosynthetic pathway. Also provided are methods of making odd chain fatty acid derivatives using the recombinant microbial cells, and compositions comprising odd chain fatty acid derivatives produced by such methods.
Abstract translation: 提供了重组微生物细胞，其已被工程化以通过脂肪酸生物合成途径产生具有含有奇数个碳原子的直链的脂肪酸衍生物。 还提供了使用重组微生物细胞制备奇数链脂肪酸衍生物的方法，以及包含通过这些方法产生的奇数链脂肪酸衍生物的组合物。
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