摘要:
This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
摘要:
The invention relates to compouns derived from betulin, and to the use thereof as antibacterial agents in pharmaceutical and cosmetic applications.
摘要:
The compound which is 2,3,3a,3b,4,5,6,6a,7,7a-decahydro-4,6,7-metheno-1H-cyclopenta[a]pentalene-1,3-dicarboxylic acid is useful as an intermediate for production of the corresponding anhydride from which several of the disclosed antipsychotic/anxiolytic agents are prepared.
摘要:
A resinous condensed cyclic alkane or alkene carboxylic
WHEREIN R1, R2, R3 and R4 are each carboxyl, alkoxycarbonyl or hydrogen but one or two of R1 to R4 are always carboxyl or alkoxycarbonyl of which the alkoxy moeity has 1 to 6 carbon atoms and, when more than one carboxyl or alkoxycarbonyl is present, they can not be present at the adjacent positions; R5 is alkyl having 1 to 6 carbon atoms which may be present at any position from the 1- to 9a-positions; m and n are each an integer of 0 or 1 but at least one of them is 1; x is an integer of 0 to 3; and not more than one double bond may be present between the positions indicated by a dotted line and, when present, carboxyl or alkoxycarbonyl can not exist at such positions, which is useful for the production of an emulsifying agent effective in the emulsion polymerization for the production of synthetic rubber.
摘要:
New herbicidal compounds of the formula IN WHICH R1 and R2 represent hydrogen or certain substituents are described as particularly suitable for controlling weeds and undesirable grasses. Compositions containing these compounds as active ingredients in mixture with agriculturally acceptable carriers and a method of controlling weeds and undesirable grasses with the aid of such compounds or compositions containing them are also described, as well as novel intermediates which are methenopentalene derivatives from which the compounds of the above formula can be produced.
R1 REPRESENTS HYDROGEN, LOWER ALIPHATIC HYDROCARBONS CYCLOALKYL, LOWER ALKOXY, OR PHENYL, R2 REPRESENTS HYDROGEN, LOWER ALKYL, OR LOWER ALKENYL, OR R1 AND R2 TOGETHER REPRESENT ETHYLENEOXYETHYLENE OR A POLYMETHYLENE BRIDGING MEMBER. ARE DESCRIBED AS PARTICULARLY SUITABLE FOR CONTROLLING WEEDS AND UNDESIRABLE GRASSES. COMPOSITIONS CONTAINING THESE COMPOUNDS AS ACTIVE INGREDIENTS IN MIXTURE WITH AGRICULTURALLY ACCEPTABLE CARRIRS AND A METHOD OF CONTROLLING WEEDS AND UNDESIRABLE GRASSES WITH THE AID OF SUCH COMPOUNDS OR COMPOSITIONS CONTAINING THEM ARE ALSO DESCRIBED, AS WELL AS INTERMEDIATES WHICH ARE METHENOPENTALENE DERIVATIVES FROM WHICH THE COMPOUNDS OF THE ABOVE FORMULA CAN BE PRODUCED.
摘要:
The present disclosure is generally directed to neuroactive substituted cyclopent[a]anthracenes as referenced herein, and pharmaceutically acceptable salts thereof, for use as, for example, an anesthetic, and/or in the treatment of disorders relating to GABA function and activity. The present disclosure is further directed to pharmaceutical compositions comprising such compounds.
摘要:
Molecular bulding beams, liquid crystals, and surfactants in the form of compounds based on [1.1.1]propellane, including poly[1.1.1]propellanes. Molecular building beams having a telomeric or polymeric chain staff, and linking groups functionalized on one or both ends of the staff. A system for linking the beams to connecting units to construct molecular structures of various forms, such as whips, combs, scaffoldings, nets, or stars. Other broad aspects of the invention provide liquid crystals and surfactants. The liquid crystals include telomeric or polymeric compounds functionalized with flexible end groups, while the surfactant compounds are functionalized with surface active end groups. Methods of synthesizing the various compounds ar also provided.
摘要:
An industrially advantageous process for producing 4-homoisotwistane-3-carboxylic acid.According to the invention, tricyclo[5.2.1.0.sup.2,6 ]dec-8-yl-methylformate (II) is contacted with an inorganic strongly acidic catalyst to obtain 4-homoisotwistane-3-carboxylic acid (I). ##STR1##