公开(公告)号：WO2006015494A1

公开(公告)日：2006-02-16

申请号：PCT/CA2005/001244

申请日：2005-08-08

Applicant: KELSAN TECHNOLOGIES CORP. ,  EADIE, Don ,  LU, Xin ,  COTTER, John

Inventor： EADIE, Don ,  LU, Xin ,  COTTER, John

IPC: C10M173/02

CPC classification number: C10M173/02 ,  B61K3/00 ,  C08K5/0008 ,  C10M169/04 ,  C10M2201/02 ,  C10M2201/041 ,  C10M2201/062 ,  C10M2201/066 ,  C10M2201/08 ,  C10M2201/081 ,  C10M2201/084 ,  C10M2201/102 ,  C10M2201/103 ,  C10M2201/1036 ,  C10M2201/105 ,  C10M2201/18 ,  C10M2205/04 ,  C10M2207/022 ,  C10M2207/026 ,  C10M2207/04 ,  C10M2209/04 ,  C10M2209/084 ,  C10M2209/10 ,  C10M2209/101 ,  C10M2209/108 ,  C10M2209/11 ,  C10M2209/12 ,  C10M2213/02 ,  C10M2213/04 ,  C10M2215/064 ,  C10M2217/028 ,  C10M2217/044 ,  C10M2217/045 ,  C10M2219/06 ,  C10M2219/085 ,  C10N2210/01 ,  C10N2210/02 ,  C10N2210/03 ,  C10N2210/08 ,  C10N2230/06 ,  C10N2240/00 ,  C10N2250/08 ,  C10N2250/10 ,  C10N2250/121 ,  C10M2205/08

Abstract: The present invention provides a water based friction control composition comprising a binder a rheological control agent, and optionally a lubricant. The liquid friction control composition may also comprise other components such as a wetting agent, a consistency modifier, and a preservative. The liquid friction control compositions may be used to modify the interfacial friction characteristics in sliding and rolling-sliding contact such as steel wheel-rail systems including mass transit and freight systems. A method of reducing lateral force, reducing energy consumption, or controlling friction between a metal surface and a second metal surface by applying the composition to metal surface, for example a top of rail or wheel, is also provided. The composition may be sprayed onto the rail surface.

Abstract translation: 本发明提供一种水基摩擦控制组合物，其包含粘合剂流变控制剂和任选的润滑剂。 液体摩擦控制组合物还可以包含其它组分，例如润湿剂，稠度调节剂和防腐剂。 液体摩擦控制组合物可用于改变滑动和滚动滑动接触中的界面摩擦特性，例如包括公共运输和货运系统的钢轮轨道系统。 还提供了一种通过将组合物施加到金属表面，例如轨道或车轮的顶部来减小横向力，降低能量消耗或控制金属表面和第二金属表面之间的摩擦力的方法。 组合物可以喷涂到轨道表面上。

公开(公告)号：WO2014110656A1

公开(公告)日：2014-07-24

申请号：PCT/CA2013/050307

申请日：2013-04-19

Applicant: HAGEL, Jeffrey ,  NAQVI, Damian

Inventor： HAGEL, Jeffrey ,  NAQVI, Damian

IPC: A61K8/73

CPC classification number: A61K8/735 ,  A61K9/0019 ,  A61K31/728 ,  A61K31/738 ,  A61K2800/74 ,  A61K2800/91 ,  A61Q19/00

Abstract: A method for increasing muscular volume of a muscle in a human is provided. The method comprises injecting a composition comprising hyaluronic acid (HA) into one or more than one location of a muscle, thereby increasing the muscular volume as compared to before the injection. The muscle may be an arm, leg, chest, back or buttock muscle, or any other desired muscle. A method for altering a contour of a muscle in a human is also provided, which comprises obtaining an image of the contour of the muscle, determining a new contour, injecting an HA composition into one or more than one location of the muscle to obtain the new contour, thereby altering the contour as compared to before the injection. A use of a composition comprising HA for increasing muscular volume of a muscle in a human is also provided, where the composition is for injection into muscle.

Abstract translation: 提供了一种增加人体肌肉体积的方法。 该方法包括将包含透明质酸（HA）的组合物注射到肌肉的一个或多于一个位置，从而与注射之前相比增加肌肉体积。 肌肉可能是手臂，腿部，胸部，背部或臀部肌肉，或任何其他所需的肌肉。 还提供了一种用于改变人体肌肉轮廓的方法，其包括获得肌肉轮廓的图像，确定新轮廓，将HA组合物注射到肌肉的一个或多于一个位置以获得 新轮廓，从而与注射前相比改变轮廓。 还提供使用组合物，其包含HA用于增加人体肌肉的体积，其中组合物用于注射到肌肉中。

公开(公告)号：WO2014053061A1

公开(公告)日：2014-04-10

申请号：PCT/CA2013/050745

申请日：2013-10-02

Applicant: WESTPORT POWER INC.

Inventor： MELANSON, Bradley E. ,  MUMFORD, David K. ,  BLOMERUS, Paul M. ,  MCKINNON, Melissa S.A.

IPC: F02M21/02 ,  F02G5/00

CPC classification number: F02M21/0287 ,  F01P2060/18 ,  F02B63/06 ,  F02B73/00 ,  F02D25/00 ,  F02G5/00 ,  F02G5/04 ,  F02M21/0245 ,  F02M21/06 ,  F02M31/125 ,  F02M31/166 ,  F02M31/18 ,  F02N19/10 ,  Y02T10/126 ,  Y02T10/16 ,  Y02T10/32 ,  Y02T30/16

Abstract: There is an improved method for supplying gaseous fuel from a liquid state to an internal combustion engine comprising employing a second internal combustion engine as a source of energy; pumping the gaseous fuel in the liquid state by transforming energy from the source of energy into mechanical work for the pumping; exchanging waste heat from the second internal combustion engine in a first heat exchange fluid circulating through the second internal combustion engine to a second heat exchange fluid; vaporizing the gaseous fuel pumped from the liquid state with heat from the second heat exchange fluid; and delivering the gaseous fuel vaporized from the liquid state to the internal combustion engine; wherein a pressure of the gaseous fuel delivered to the internal combustion engine is maintained within a predetermined range of tolerance by the pumping.

Abstract translation: 一种用于将气态燃料从液态供应到内燃机的改进方法，包括采用第二内燃机作为能量源; 通过将来自能量源的能量转换成用于泵送的机械作业来泵送处于液态的气态燃料; 在通过所述第二内燃机循环的第一热交换流体中将来自所述第二内燃机的废热换成第二热交换流体; 使来自第二热交换流体的热量从液体状态泵出的气体燃料蒸发; 以及将从所述液态蒸发的所述气态燃料输送到所述内燃机; 其中输送到内燃机的气体燃料的压力通过泵送保持在预定的公差范围内。

公开(公告)号：WO2013123594A1

公开(公告)日：2013-08-29

申请号：PCT/CA2013/050106

申请日：2013-02-08

Applicant: WESTPORT POWER INC.

Inventor： HARPER, Gregory C. ,  LARSON, Nikke E. ,  AGHDAM, Kamal Hatami ,  DIN, Tahir A.

IPC: B65H81/00 ,  F16L59/00 ,  F17C1/12 ,  F17C3/04

CPC classification number: B65H81/00 ,  B29C53/56

Abstract: A method and apparatus for wrapping insulation around a vessel comprising rotating the vessel about an axis; wrapping insulation around the vessel in a plane offset from the axis as the vessel rotates; and translating one end of the vessel relative to the plane as the vessel rotates, the relative translation between the one end and the plane is along a path of translation; whereby a portion of the vessel at the one end remains uncovered, a shape of the portion is influenced by the path of translation.

Abstract translation: 一种围绕容器缠绕绝缘的方法和装置，包括围绕轴线旋转容器; 在容器旋转时在与轴线偏移的平面内围绕容器缠绕绝缘体; 并且随着容器旋转，平移容器的一端相对于平面，一端和平面之间的相对平移沿着平移的路径; 由此一端的容器的一部分保持未被覆盖，该部分的形状受平移路径的影响。

公开(公告)号：WO2013056347A1

公开(公告)日：2013-04-25

申请号：PCT/CA2012/000957

申请日：2012-10-15

Applicant: WESTPORT POWER INC.

Inventor： WICKSTONE, Michael, C.

IPC: F02M43/00 ,  F02D19/08 ,  F02M61/14

CPC classification number: F02M61/14 ,  F02D19/066 ,  F02D19/08 ,  F02M43/00 ,  F02M43/04 ,  F02M55/02 ,  F02M55/025 ,  Y02T10/36

Abstract: A multifunctional spacer is provided for a dual fuel internal combustion engine. The spacer provides a separate passage for supplying a second fuel to a dual fuel injection valve of the engine wherein the passage for supplying a first fuel to the dual fuel injection valve is provided separately in the cylinder head. The spacer is located on top of the cylinder head and it also serves the purpose of extending the bore provided in the cylinder head for accommodating the dual fuel injection valve. In some embodiments the spacer can provide support for different parts of the actuating mechanism for the cylinder's intake and exhaust valves.

Abstract translation: 为双燃料内燃机提供多功能间隔件。 间隔件提供用于将第二燃料供应到发动机的双燃料喷射阀的单独通道，其中用于向双燃料喷射阀供应第一燃料的通道分别设置在气缸盖中。 间隔件位于气缸盖的顶部，并且其还用于延伸设置在气缸盖中的孔以容纳双燃料喷射阀。 在一些实施例中，间隔件可以为气缸的进气门和排气门的致动机构的不同部分提供支撑。

公开(公告)号：WO2012083445A1

公开(公告)日：2012-06-28

申请号：PCT/CA2011/001427

申请日：2011-12-22

Applicant: MEDICAGO INC. ,  D'AOUST, Marc-Andre ,  COUTURE, Manon ,  LAVOIE, Pierre-Olivier ,  VEZINA, Louis-Philippe

Inventor： D'AOUST, Marc-Andre ,  COUTURE, Manon ,  LAVOIE, Pierre-Olivier ,  VEZINA, Louis-Philippe

IPC: C12N15/00 ,  A61K39/295 ,  A61P31/16 ,  A61P37/04 ,  C07K19/00 ,  C12N15/62 ,  C12N15/82 ,  C12N7/00 ,  C07K14/005 ,  C07K14/11

CPC classification number: A61K39/295 ,  A61K2039/5258 ,  C07K14/005 ,  C07K2319/03 ,  C12N7/00 ,  C12N15/8257 ,  C12N15/8258 ,  C12N2710/16723 ,  C12N2710/16751 ,  C12N2740/16023 ,  C12N2740/16034 ,  C12N2740/16051 ,  C12N2740/16134 ,  C12N2760/14123 ,  C12N2760/14134 ,  C12N2760/14151 ,  C12N2760/16123 ,  C12N2760/20123 ,  C12N2760/20134 ,  C12N2760/20151 ,  C12N2770/20023 ,  C12N2770/20034 ,  C12N2770/20051

Abstract: A method of producing a virus like particle (VLP) in a plant, and compositions comprising VLPs, are provided. The method involves introducing a nucleic acid comprising a regulatory region active in the plant and operatively linked to a chimeric nucleotide sequence encoding, in series, an ectodomain from a virus trimeric surface protein or fragment thereof, fused to an influenza transmembrane domain and cytoplasmic tail, into the plant, or portion of the plant, the ectodomain is from a non- influenza virus trimeric surface protein and heterologous with respect to the influenza transmembrane domain, and the cytoplasmic tail. The plant or portion of the plant are incubated under conditions that permit the expression of the nucleic acid, thereby producing the VLP. A VLP produced by this method are also provided.

Abstract translation: 提供了在植物中产生病毒样颗粒（VLP）的方法和包含VLP的组合物。 所述方法包括将包含在植物中有活性的调节区的核酸引入，并与编码融合至流感跨膜结构域和细胞质尾的病毒三聚体表面蛋白或其片段的胞外域串联编码的嵌合核苷酸序列可操作地连接， 进入植物或植物的部分中，胞外域来自非流感病毒三聚体表面蛋白并且相对于流感跨膜结构域和细胞质尾部是异源的。 在允许核酸表达的条件下孵育植物或植物部分，从而产生VLP。 还提供了由此方法生成的VLP。

公开(公告)号：WO2011035423A1

公开(公告)日：2011-03-31

申请号：PCT/CA2010/001489

申请日：2010-09-21

Applicant: MEDICAGO INC. ,  VEZINA, Louis-Philippe ,  COUTURE, Manon ,  PAQUET, Dany ,  DARGIS, Michele ,  D'AOUST, Marc-Andre

Inventor： VEZINA, Louis-Philippe ,  COUTURE, Manon ,  PAQUET, Dany ,  DARGIS, Michele ,  D'AOUST, Marc-Andre

IPC: C07K1/14 ,  C07K1/34 ,  C07K14/415 ,  C12N5/04 ,  C12N15/00 ,  C12N15/82

CPC classification number: A61K39/145 ,  A61K39/12 ,  A61K2039/517 ,  A61K2039/5258 ,  C12N7/00 ,  C12N15/8203 ,  C12N15/8257 ,  C12N15/8258 ,  C12N2760/16123 ,  C12N2760/16134

Abstract: Methods of preparing plant-derived proteins or suprastructure proteins, are provided. The method may comprise obtaining a plant, or plant matter comprising apoplast-localized proteins, or suprastructure proteins, producing a protoplast/spheroplast fraction and apoplast fraction from the plant or plant matter, and recovering the apoplast fraction. The apoplast fraction comprises plant-derived proteins or suprastructure proteins,. Alternatively, the proteins, or suprastructure proteins, may be obtained from plant or plant matter comprising plant-derived proteins or suprastructure proteins, by digesting the plant matter using a cell wall degrading enzyme composition to produced a digested fraction. The digested fraction is filtered to produced a filtered fraction, and the plant-derived proteins or suprastructure proteins, are recovered from the filtered fraction.

Abstract translation: 提供了制备植物衍生蛋白或超基质蛋白的方法。 该方法可以包括获得植物或包含质外体蛋白质定位蛋白质的植物物质或超基质蛋白，从植物或植物物质产生原生质体/原生质体级分和质外体级分，并回收载脂蛋白级分。 载脂蛋白级分包含植物来源的蛋白质或超基因蛋白质。 或者，可以通过使用细胞壁降解酶组合物消化植物物质以产生消化部分，从包含植物衍生的蛋白质或超基质蛋白质的植物或植物物质获得蛋白质或超基质蛋白质。 将消化的馏分过滤以产生过滤的馏分，从过滤的馏分中回收植物来源的蛋白质或超结构蛋白质。

公开(公告)号：WO2010148511A1

公开(公告)日：2010-12-29

申请号：PCT/CA2010/000983

申请日：2010-06-25

Applicant: MEDICAGO, INC. ,  COUTURE, Manon ,  DARGIS, Michele ,  LAVOIE, Pierre-Olivier ,  VEZINA, Louis-Philippe ,  D'AOUST, Marc-Andre

Inventor： COUTURE, Manon ,  DARGIS, Michele ,  LAVOIE, Pierre-Olivier ,  VEZINA, Louis-Philippe ,  D'AOUST, Marc-Andre

IPC: C07K14/11 ,  A01H5/00 ,  A61K39/145 ,  A61P31/16 ,  C12N15/44 ,  C12N15/82 ,  C12N7/00 ,  C12N7/01 ,  C07K19/00

CPC classification number: A61K39/145 ,  A61K39/12 ,  A61K2039/5258 ,  C07K14/005 ,  C07K2319/00 ,  C07K2319/02 ,  C12N15/8257 ,  C12N2760/16122 ,  C12N2760/16123 ,  C12N2760/16134 ,  C12N2760/16222 ,  C12N2760/16223 ,  C12N2760/16234

Abstract: A method for synthesizing chimeric influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of chimeric influenza HA in a plant or a portion of a plant. The invention is also directed towards a VLP comprising chimeric influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding chimeric influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines.

Abstract translation: 提供了在植物或植物的一部分内合成嵌合型流感病毒样颗粒（VLP）的方法。 该方法包括在植物或植物的一部分中表达嵌合流感HA。 本发明还涉及包含嵌合流感HA蛋白和植物脂质的VLP。 本发明还涉及编码嵌合流感HA以及载体的核酸。 VLP可用于制定流感疫苗，或可用于丰富现有疫苗。

公开(公告)号：WO2010096903A1

公开(公告)日：2010-09-02

申请号：PCT/CA2010/000212

申请日：2010-02-16

Applicant: WESTPORT POWER INC. ,  BROOK, Thomas ,  LEBLANC, Valerie

Inventor： BROOK, Thomas ,  LEBLANC, Valerie

IPC: F17C13/00 ,  B65D90/34 ,  F02M21/04 ,  F17C9/02

CPC classification number: F17C9/00 ,  F02D19/022 ,  F02D19/027 ,  F02M21/0215 ,  F02M21/0221 ,  F02M21/0287 ,  F02M21/06 ,  F17C9/02 ,  F17C13/025 ,  F17C2221/011 ,  F17C2221/012 ,  F17C2221/013 ,  F17C2221/014 ,  F17C2221/033 ,  F17C2223/0161 ,  F17C2223/033 ,  F17C2223/043 ,  F17C2223/046 ,  F17C2225/033 ,  F17C2225/044 ,  F17C2227/0107 ,  F17C2227/0309 ,  F17C2227/039 ,  F17C2227/0393 ,  F17C2250/032 ,  F17C2250/043 ,  F17C2250/0626 ,  F17C2265/031 ,  F17C2265/036 ,  F17C2265/066 ,  Y02E60/321 ,  Y02T10/32

Abstract: A pressure control system comprises separate conduits for supplying liquefied gas and vapour from a cryogen space defined by a cryogenic storage tank. A first conduit can deliver liquefied gas to a use device through a heater and then a first flow controller. A second conduit can deliver vapour to the use device with flow therethrough controlled by a second flow controller. The first flow controller is not exposed to liquefied gas at cryogenic temperatures because it is located downstream from the heater. For automatic operation a pressure sensor measures pressure inside the cryogen space and the first and second flow controllers are independently operable to maintain the pressure inside the cryogen space within a predetermined range. In a preferred embodiment the liquefied gas is a combustible fuel that is consumed by an internal combustion engine, which is the use device.

Abstract translation: 压力控制系统包括用于从由低温储罐限定的冷冻剂空间供应液化气体和蒸气的分离的管道。 第一管道可以通过加热器然后第一流量控制器将液化气体输送到使用装置。 第二导管可以将蒸气输送到使用装置，其中流动通过第二流量控制器控制。 第一个流量控制器在低温下不会暴露于液化气体，因为它位于加热器的下游。 为了自动操作，压力传感器测量制冷剂空间内的压力，并且第一和第二流量控制器可独立地操作以将冷冻剂空间内的压力保持在预定范围内。 在优选实施例中，液化气体是被作为使用装置的内燃机消耗的可燃燃料。

公开(公告)号：WO2009026722A1

公开(公告)日：2009-03-05

申请号：PCT/CA2008/001546

申请日：2008-08-29

Applicant: IOGEN ENERGY CORPORATION ,  SCOTT, Brian R. ,  HILL, Christopher ,  TOMASHEK, John ,  LIU, Chengsong

Inventor： SCOTT, Brian R. ,  HILL, Christopher ,  TOMASHEK, John ,  LIU, Chengsong

IPC: C12P19/02 ,  C12N9/24 ,  C12N9/42 ,  C12P19/00

CPC classification number: C12N9/2437 ,  C12N9/2445 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004 ,  C12Y302/01021 ,  C12Y302/01091 ,  Y02E50/17

Abstract: Provided is an enzyme mixture for hydrolyzing a pretreated lignocellulosic feedstock to soluble sugars. The enzyme mixture comprises EG4 at a fractional concentration (fEG4) of about 0.09 to about 0.91 (w/w), Swollenin at a fractional concentration (f S wo1 ) of about 0 to about 0.91(w/w), and Cip1 at a fractional concentration (f Cip1 ) of 0 to about 0.42 measured relative to all of the accessory enzymes present in the enzyme mixture. Also provided are processes for converting a pretreated lignocellulosic feedstock to soluble sugars using the enzyme mixtures, and methods of using and producing such enzyme mixtures.

Abstract translation: 提供了用于将预处理的木质纤维素原料水解成可溶性糖的酶混合物。 酶混合物包含约0.09至约0.91（w / w）的分数浓度（fEG4）的EG4，分数浓度（fSw1）为约0至约0.91（w / w）的溶血素，和分数浓度的Cip1 相对于存在于酶混合物中的所有辅助酶，测量的浓度（fCip1）为0至约0.42。 还提供了使用酶混合物将预处理的木质纤维素原料转化为可溶性糖的方法，以及使用和生产这种酶混合物的方法。