公开(公告)号：WO2012048035A3

公开(公告)日：2012-07-19

申请号：PCT/US2011054973

申请日：2011-10-05

Applicant: EDWARDS LIFESCIENCES CORP ,  LEVI TAMIR ,  NGUYEN SON V ,  BENICHOU NETANEL ,  MAIMON DAVID ,  YOHANAN ZIV ,  GUROVICH NIK ,  FELSEN BELLA ,  DADONKIN LARISA

Inventor： LEVI TAMIR ,  NGUYEN SON V ,  BENICHOU NETANEL ,  MAIMON DAVID ,  YOHANAN ZIV ,  GUROVICH NIK ,  FELSEN BELLA ,  DADONKIN LARISA

IPC: A61F2/24 ,  A61M29/02

CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2/2433 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/0036 ,  A61F2250/0097

Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.

Abstract translation: 公开了径向可折叠和可扩张假体心脏瓣膜的实施例。 阀框架在安装在输送轴上时可具有锥形轮廓，其中流入端部的直径小于流出端部的直径。 瓣膜可以包括大致V形小叶，从而减少了在框架流入端内的物质。 外裙部可以固定到框架的流入端部的外侧，当瓣膜膨胀时，外裙部具有纵向松弛并且当瓣膜塌陷时平躺在框架上。 对角编织的内裙部可以与框架轴向延伸。 相邻小叶的侧翼可延伸穿过并固定到框架的窗框部分以形成连合。 当阀压接到输送轴上时，窗框部分可相对于周围框架部分径向向内凹陷。

公开(公告)号：WO2006096813A3

公开(公告)日：2006-09-14

申请号：PCT/US2006/008449

申请日：2006-03-08

Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION ,  SONY CORPORATION ,  NGUYEN, Son, V. ,  LANE, Sarah, L. ,  LINIGER, Eric, G. ,  IDA, Kensaku ,  RESTAINO, Darryl, D.

Inventor： NGUYEN, Son, V. ,  LANE, Sarah, L. ,  LINIGER, Eric, G. ,  IDA, Kensaku ,  RESTAINO, Darryl, D.

IPC: H01L23/48 ,  H01L23/52 ,  H01L29/40

Abstract: A material stack (12) is provided comprising one or more films (14) that have a crack velocity of about IE- 10 m/sec or greater and at least one monolayer (16) within or in direct contact with the one or more films (14), wherein the at least one monolayer (16) reduces the crack velocity of the material stack (12) to a value of less than lE-10 m/sec. The one or more films ( 14) are not limited to low k dielectrics, but may include materials such as a metal. In a preferred embodiment, a low k dielectric stack (12) is provided, having an effective dielectric constant k, of about 3.0 or less, in which the mechanical properties of the stack (12) are improved by introducing at least one nanolayer (16) into the dielectric stack (12). The improvement in mechanical properties is achieved without significantly increasing the dielectric constant of me films within the stack (12) and without the need of subjecting the inventive dielectric stack (12) to any post treatment steps.

公开(公告)号：WO2009134701A3

公开(公告)日：2010-02-11

申请号：PCT/US2009041754

申请日：2009-04-27

Applicant: EDWARDS LIFESCIENCES CORP ,  ROWE STANTON J ,  CHAU MARK ,  NGUYEN SON V

Inventor： ROWE STANTON J ,  CHAU MARK ,  NGUYEN SON V

IPC: A61F2/90 ,  A61F2/24

CPC classification number: A61F2/2418 ,  A61B17/0401 ,  A61B2017/00243 ,  A61B2017/0417 ,  A61B2017/0496 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2/2457 ,  A61F2/90 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0078 ,  A61L27/3625 ,  A61L27/50 ,  A61L2430/20

Abstract: A prosthetic mitral valve assembly is disclosed. In certain disclosed embodiments, the prosthetic mitral valve assembly has a flared upper end and a tapered portion to fit the contours of the native mitral valve. The prosthetic mitral valve assembly includes a stent or outer support frame with a valve mounted therein. The assembly can be adapted to expand radially outwardly and into contact with the native tissue to create a pressure fit. The mitral valve assembly further includes tension members between the leaflets of the valve assembly and a suitable location on the heart.

Abstract translation: 公开了一种假体二尖瓣组件。 在某些公开的实施例中，假体二尖瓣组件具有扩张的上端和锥形部分以适应天然二尖瓣的轮廓。 假体二尖瓣组件包括其中安装有阀的支架或外部支撑框架。 组件可以适于径向向外膨胀并与天然组织接触以产生压力配合。 二尖瓣组件还包括在阀组件的传单和心脏上的适当位置之间的张力构件。

公开(公告)号：WO2006088881A2

公开(公告)日：2006-08-24

申请号：PCT/US2006/005204

申请日：2006-02-14

Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION ,  SONY CORPORATION ,  NGUYEN, Son, V. ,  LANE, Sarah, L. ,  LEE, Jia ,  IDA, Kensaku ,  RESTAINO, Darryl, D. ,  NOGAMI, Takeshi

Inventor： NGUYEN, Son, V. ,  LANE, Sarah, L. ,  LEE, Jia ,  IDA, Kensaku ,  RESTAINO, Darryl, D. ,  NOGAMI, Takeshi

IPC: H01L21/31

CPC classification number: H01L21/7682 ,  C23C16/401 ,  H01L21/02126 ,  H01L21/02203 ,  H01L21/02216 ,  H01L21/02274 ,  H01L21/0234 ,  H01L21/02348 ,  H01L21/02351 ,  H01L21/02354 ,  H01L21/3122 ,  H01L21/31633 ,  H01L2221/1047

Abstract: A porous low k or ultra low k dielectric film comprising atoms of Si, C, O and H (hereinafter "SiCOH") in a covalently bonded tri-dimensional network structure having a dielectric constant of less than about 3.0, a higher degree of crystalline bonding interactions, more carbon as methyl termination groups and fewer methylene, -CH 2 - crosslinking groups than prior art SiCOH dielectrics is provided. The SiCOH dielectric is characterized as having a FTIR spectrum comprising a peak area for CH 3 +CH 2 stretching of less than about 1.40, a peak area for SiH stretching of less than about 0.20, a peak area for SiCH 3 bonding of greater than about 2.0, and a peak area for Si-O-Si bonding of greater than about 60%, and a porosity of greater than about 20%.

Abstract translation: 在介电常数小于约3.0的共价键合的三维网络结构中，包含Si，C，O和H原子（以下称为“SiCOH”）的多孔低k或超低k电介质膜，结晶度更高 键合相互作用，提供比现有技术的SiCOH电介质更多的碳作为甲基端基和较少的亚甲基-CH 2 - 2交联基团。 SiCOH电介质的特征在于具有包含小于约1.40的CH 3 N 2 CH 2拉伸的峰面积的FTIR光谱，SiH拉伸的峰面积小于 约0.20，SiCH 3键的峰面积大于约2.0，Si-O-Si键合的峰面积大于约60％，孔隙率大于约20％ 。

公开(公告)号：WO2018063198A1

公开(公告)日：2018-04-05

申请号：PCT/US2016/054240

申请日：2016-09-28

Applicant: ALEKSOV, Aleksandar ,  NGUYEN, Son V. ,  GOYAL, Rajat ,  LAMPNER, David B. ,  SENEVIRATNE, Dilan ,  LOPEZ, Albert S. ,  HEPPNER, Joshua D. ,  PIETAMBARAM, Srinivas V. ,  LIFF, Shawna M. ,  DABBY, Nadine L.

Inventor： ALEKSOV, Aleksandar ,  NGUYEN, Son V. ,  GOYAL, Rajat ,  LAMPNER, David B. ,  SENEVIRATNE, Dilan ,  LOPEZ, Albert S. ,  HEPPNER, Joshua D. ,  PIETAMBARAM, Srinivas V. ,  LIFF, Shawna M. ,  DABBY, Nadine L.

IPC: G04G17/04 ,  G04B37/14 ,  A44C5/00 ,  G06F1/16

Abstract: The document discloses a stretchable packaging system for a wearable electronic device. The system includes a first electronic component and a flexible trace connected to the first electronic component. An elastomer layer having a variable thickness at least partially encapsulates the first electronic component and the flexible trace. A first region of the layer has a first thickness that is greater than a second thickness of a second region of the layer that at least partially encapsulates the trace.

Abstract translation: 该文献公开了用于可穿戴电子设备的可拉伸包装系统。 该系统包括第一电子部件和连接到第一电子部件的柔性迹线。 具有可变厚度的弹性体层至少部分地封装第一电子部件和柔性迹线。 该层的第一区域具有第一厚度，该第一厚度大于至少部分地封装迹线的层的第二区域的第二厚度。

公开(公告)号：WO2012048035A2

公开(公告)日：2012-04-12

申请号：PCT/US2011/054973

申请日：2011-10-05

Applicant: EDWARDS LIFESCIENCES CORPORATION ,  LEVI, Tamir ,  NGUYEN, Son, V. ,  BENICHOU, Netanel ,  MAIMON, David ,  YOHANAN, Ziv ,  GUROVICH, Nik ,  FELSEN, Bella ,  DADONKIN, Larisa

Inventor： LEVI, Tamir ,  NGUYEN, Son, V. ,  BENICHOU, Netanel ,  MAIMON, David ,  YOHANAN, Ziv ,  GUROVICH, Nik ,  FELSEN, Bella ,  DADONKIN, Larisa

IPC: A61F2/24 ,  A61M29/02

CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2/2433 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/0036 ,  A61F2250/0097

Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.

Abstract translation: 公开了径向可折叠和可扩张的假体心脏瓣膜的实施例。 当安装在输送轴上时，阀架可以具有锥形轮廓，流入端部的直径小于流出端部分的直径。 阀可以包括大致V形的小叶，在框架的流入端内还原材料。 外裙可以固定到框架的流入端部分的外部，当阀门膨胀时，外裙部具有纵向松弛，并且当阀门折叠时，外裙部平放在框架上。 对角编织的内裙可以与框架轴向伸长。 相邻小叶的侧翼可以延伸穿过并固定到框架的窗框部分以形成连合。 当阀被压接到输送轴上时，窗框部分可以相对于周围的框架部分径向向内按压。

公开(公告)号：WO2006096813A2

公开(公告)日：2006-09-14

申请号：PCT/US2006008449

申请日：2006-03-08

Applicant: IBM ,  SONY CORP ,  NGUYEN SON V ,  LANE SARAH L ,  LINIGER ERIC G ,  IDA KENSAKU ,  RESTAINO DARRYL D

Inventor： NGUYEN SON V ,  LANE SARAH L ,  LINIGER ERIC G ,  IDA KENSAKU ,  RESTAINO DARRYL D

IPC: H01L21/469 ,  H01L23/52 ,  H01L23/58

CPC classification number: H01L21/76801 ,  H01L21/02126 ,  H01L21/022 ,  H01L21/02216 ,  H01L21/02274 ,  H01L21/0234 ,  H01L21/02348 ,  H01L21/02351 ,  H01L21/02354 ,  H01L21/3105 ,  H01L21/31633 ,  H01L21/76825 ,  H01L21/76826 ,  H01L21/76828 ,  H01L21/76829 ,  H01L21/76834 ,  H01L23/5222 ,  H01L23/53295 ,  H01L2924/0002 ,  H01L2924/00

Abstract: A material stack (12) is provided comprising one or more films (14) that have a crack velocity of about IE- 10 m/sec or greater and at least one monolayer (16) within or in direct contact with the one or more films (14), wherein the at least one monolayer (16) reduces the crack velocity of the material stack (12) to a value of less than lE-10 m/sec. The one or more films ( 14) are not limited to low k dielectrics, but may include materials such as a metal. In a preferred embodiment, a low k dielectric stack (12) is provided, having an effective dielectric constant k, of about 3.0 or less, in which the mechanical properties of the stack (12) are improved by introducing at least one nanolayer (16) into the dielectric stack (12). The improvement in mechanical properties is achieved without significantly increasing the dielectric constant of me films within the stack (12) and without the need of subjecting the inventive dielectric stack (12) to any post treatment steps.

Abstract translation: 提供材料堆叠（12），其包括一个或多个膜（14），其具有大约IE-10m / sec或更大的裂纹速度和至少一个单层（16）在一个或多个膜内或直接接触一个或多个膜 （14），其中所述至少一个单层（16）将所述材料堆叠（12）的裂纹速度降低到小于1E-10m / sec的值。 一个或多个膜（14）不限于低k电介质，而是可以包括诸如金属的材料。 在优选实施例中，提供具有约3.0或更小的有效介电常数k的低k电介质堆叠（12），其中通过引入至少一个纳米层（16）来提高堆叠（12）的机械性能 ）到介电叠层（12）中。 在不显着增加叠层（12）内的薄膜的介电常数并且不需要对本发明的电介质叠层（12）进行任何后处理步骤的情况下，实现机械性能的改善。

公开(公告)号：WO2010099032A2

公开(公告)日：2010-09-02

申请号：PCT/US2010/024665

申请日：2010-02-19

Applicant: EDWARDS LIFESCIENCES CORPORATION ,  CHAU, Mark ,  YI, Seung ,  CORSO, Phillip ,  POPP, Michael, J. ,  OLIN, Jane ,  NGUYEN, Son, V. ,  GOLEMO, Kevin

Inventor： CHAU, Mark ,  YI, Seung ,  CORSO, Phillip ,  POPP, Michael, J. ,  OLIN, Jane ,  NGUYEN, Son, V. ,  GOLEMO, Kevin

IPC: A61F2/24 ,  A61F2/86 ,  A61F2/84 ,  A61M29/00 ,  A61L27/04 ,  A61L27/14

CPC classification number: A61F2/2457 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0039

Abstract: A prosthetic mitral valve assembly and method of inserting the same is disclosed. In certain disclosed embodiments, the prosthetic mitral valve assembly includes a stent and valve combination. The stent is designed so that the anchoring portion is positioned above the annulus of the mitral valve and in the left atrium. The stent is radially expandable so that it can expand into position against the walls of the left atrium and accommodate a wide range of anatomies. Contact between the stent and the native tissue in the left atrium reduces paravalvular leakage and prevents migration of the stent once in place.

Abstract translation: 公开了一种假体二尖瓣组件及其插入方法。 在某些公开的实施例中，假体二尖瓣组件包括支架和瓣膜组合。 支架被设计成使得锚固部分位于二尖瓣环和左心房的环上。 支架是径向可扩张的，使得其能够相对于左心房的壁膨胀到适当的位置并适应宽范围的解剖结构。 支架与左心房中的天然组织之间的接触减少了瓣膜渗漏，并防止了支架移动到位。

公开(公告)号：WO2006088881A3

公开(公告)日：2007-01-18

申请号：PCT/US2006005204

申请日：2006-02-14

Applicant: IBM ,  SONY CORP ,  NGUYEN SON V ,  LANE SARAH L ,  LEE JIA ,  IDA KENSAKU ,  RESTAINO DARRYL D ,  NOGAMI TAKESHI

Inventor： NGUYEN SON V ,  LANE SARAH L ,  LEE JIA ,  IDA KENSAKU ,  RESTAINO DARRYL D ,  NOGAMI TAKESHI

IPC: H01L21/31

CPC classification number: H01L21/7682 ,  C23C16/401 ,  H01L21/02126 ,  H01L21/02203 ,  H01L21/02216 ,  H01L21/02274 ,  H01L21/0234 ,  H01L21/02348 ,  H01L21/02351 ,  H01L21/02354 ,  H01L21/3122 ,  H01L21/31633 ,  H01L2221/1047

Abstract: A porous low k or ultra low k dielectric film comprising atoms of Si, C, O and H (hereinafter "SiCOH") in a covalently bonded tri-dimensional network structure having a dielectric constant of less than about 3.0, a higher degree of crystalline bonding interactions, more carbon as methyl termination groups and fewer methylene, -CH 2 - crosslinking groups than prior art SiCOH dielectrics is provided. The SiCOH dielectric is characterized as having a FTIR spectrum comprising a peak area for CH 3 +CH 2 stretching of less than about 1.40, a peak area for SiH stretching of less than about 0.20, a peak area for SiCH 3 bonding of greater than about 2.0, and a peak area for Si-O-Si bonding of greater than about 60%, and a porosity of greater than about 20%.

Abstract translation: 在介电常数小于约3.0的共价键合的三维网络结构中，包含Si，C，O和H原子（以下称为“SiCOH”）的多孔低k或超低k电介质膜，结晶度更高 键合相互作用，提供比现有技术的SiCOH电介质更多的碳作为甲基端基和更少的亚甲基-CH 2 - 2交联基团。 SiCOH电介质的特征在于具有小于约1.40的CH 3 N 2 CH 2拉伸峰面积的FTIR光谱，SiH拉伸的峰面积小于 约0.20，SiCH 3键的峰面积大于约2.0，Si-O-Si键合的峰面积大于约60％，孔隙率大于约20％ 。

公开(公告)号：WO2010099032A3

公开(公告)日：2011-01-06

申请号：PCT/US2010024665

申请日：2010-02-19

Applicant: EDWARDS LIFESCIENCES CORP ,  CHAU MARK ,  YI SEUNG ,  CORSO PHILLIP ,  POPP MICHAEL J ,  OLIN JANE ,  NGUYEN SON V ,  GOLEMO KEVIN

Inventor： CHAU MARK ,  YI SEUNG ,  CORSO PHILLIP ,  POPP MICHAEL J ,  OLIN JANE ,  NGUYEN SON V ,  GOLEMO KEVIN

IPC: A61F2/24 ,  A61F2/84 ,  A61F2/86 ,  A61L27/04 ,  A61L27/14 ,  A61M29/00

CPC classification number: A61F2/2457 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0039

Abstract: A prosthetic mitral valve assembly and method of inserting the same is disclosed. In certain disclosed embodiments, the prosthetic mitral valve assembly includes a stent and valve combination. The stent is designed so that the anchoring portion is positioned above the annulus of the mitral valve and in the left atrium. The stent is radially expandable so that it can expand into position against the walls of the left atrium and accommodate a wide range of anatomies. Contact between the stent and the native tissue in the left atrium reduces paravalvular leakage and prevents migration of the stent once in place.

Abstract translation: 公开了一种假体二尖瓣组件及其插入方法。 在某些公开的实施例中，假体二尖瓣组件包括支架和瓣膜组合。 支架被设计成使得锚固部分位于二尖瓣环和左心房的环上。 支架是径向可扩张的，使得其能够相对于左心房的壁膨胀到适当的位置并适应宽范围的解剖结构。 支架与左心房中的天然组织之间的接触减少了瓣膜渗漏，并防止了支架移动到位。