Abstract:
This document provides methods and materials for treating brain injuries. For example, methods and materials for using nucleic acid encoding a NeuroD1 polypeptide to convert reactive astrocytes within a brain ( e.g. , cerebral cortex) into functional neurons ( e.g. , neurons that can be functionally integrated into the brain of a living mammal ( e.g. , a human)) are provided.
Abstract:
Provided herein are processes for synthesizing compounds useful as EGFR modulators. In particular, provided herein are processes for synthesizing Compound A:
Abstract:
A method and system for allocating video scaling resources in a deep learning model across a communication network. The method comprises estimating a first set of layers of the deep learning model for downscaling of a video content stream generated at a video server of the communication network; estimating a second set of layers of the deep learning model for upscaling of the video content stream at a rendering device of the communication network; and allocating resources amongst the video server and the rendering device at least partly in accordance with the first set and the second set, wherein the allocating minimizes resources allocated for upscaling at the rendering device and optimizes the video quality of the video displayed at the rendering device.
Abstract:
A method for interactive image caricaturing by an electronic device is described. The method includes detecting at least one feature location of an image, The method further includes generating, based on the at least one feature location, an image mesh that comprises a grid of at least one horizontal line and at least one vertical line. The method additionally includes obtaining a gesture input. The method also includes determining at least one caricature action based on the at least one gesture input. The method further includes generating a caricature image based on the image mesh, the at least one caricature action and the image.
Abstract:
A system for controlling operation of a motor drive during fast start-up of an induction motor includes an AC motor drive having a PWM inverter and a control system to generate a command signal to cause the PWM inverter to control an output of the AC motor drive. The control system includes a start-up modulator that is selectively operable during start-up acceleration of the AC motor, the start-up modulator programmed to determine a motor current applied to the AC motor and a voltage of a DC bus, generate a first frequency offset that causes a frequency reference of the command signal to be decreased when the motor current is greater than a reference current threshold, and generate a second frequency offset that causes the frequency reference of the command signal to be increased when the DC bus voltage is greater than a reference voltage threshold.
Abstract:
Catalyst Systems, processes of forming the same and polymers and polymerization processes are described herein. The process of forming the catalyst system generally includes providing a first compound including a magnesium dialkoxide and aluminum alkoxide; contacting the first compound with a first agent and a second agent to form a solution of reaction product "A", the first agent including a titanating agent and the second agent including a first metal halide; contacting the solution of reaction product "A" with a third agent to form a solid reaction product "B", the third agent including a second metal halide; contacting the solid reaction product "B" with a fourth agent to form a solid reaction product "C", the fourth agent including a third metal halide; optionally contacting the solid reaction product "C" with a fifth agent to form a solid reaction product "D", the fifth agent including a fourth metal halide; and contacting the solid reaction product "C" or "D" with a sixth agent to form a catalyst component, the sixth agent including a first organoaluminum compound.
Abstract:
Die Erfindung betrifft eine Kabeltrommel zur selbsttätigen Aufwicklung eines Kabels, mit einem inneren Trommelteil (2), einen äußeren Trommelteil (1) und einer Rücken platte (3). An dem inneren Trommelteil (2) ist eine hohlzylindrische Kulisse (23) angeformt, in deren Innenwandung wenigstens eine Einwölbung (24) eingebracht ist, wobei an der Rückenplatte (3) ein Bremshebel (6) radial verschiebbar gelagert ist, der wenigstens ein Langloch (63) aufweist, in dem die Achse (71 ) eines Bremsrades (7) geführt ist, das in die Kulisse (23) hineinragt und an deren Innenwandung anliegt, wobei das wenigstens eine Langloch (63) derart winklig positioniert ist, dass das Bremsrad (7) bei Rotation der Kulisse (23) in Aufwickelrichtung der Kabeltrommel gegen die Innenwandung der Kulisse (23) gepresst wird und wobei an dem Bremshebel (6) ein Blockierelement dem Bremsrad (7) in Aufwickelrichtung der Kabeltrommel nachgelagert angeordnet ist, das derart mit wenigstens einem an dem inneren Trommelteil (2) angeordneten Fangteil zusammenwirkt, dass dieses nur bei Passieren des Fangteils in Aufwickelrichtung der Kabeltrommel blockiert wird.
Abstract:
The present invention relates to compounds of Formula I as described herein or a 1 pharmaceutically acceptable salt thereof, pharmaceutical composition comprising a compound of Formula I or a pharmaceutically acceptable salt thereof and methods of treating, or manufacture of a medicament to treat, a disease, disorder, or condition of the central nervous system, including bipolar disorder, depressive disorders, anxiety disorders, cognitive disorders, pain disorders, urogenital disorders, and epilepsy, among the other diseases, disorders or conditions discussed herein as mono-therapy or in combination with another active pharmaceutical ingredient.
Abstract:
A method of forming catalysts including contacting an alkyl magnesium compound with a viscosity modifier prior to contact with an alcohol to form a magnesium dialkoxide compound; contacting the magnesium dialkoxide compound with a first titanium alkoxide and a first agent to form a first solution reaction product "A", wherein the titanium alkoxide and the first agent are non-blended individual components prior to contacting the magnesium dialkoxide; contacting the first solution reaction product ?A? with a second titanium alkoxide to form a second solulion reaction product ?B?contacting the second solution reaction product ?B? with a second agent to form a first solid reaction product ?C?; contacting the first solid reaction product ?C? with a third agent to form a second solid reaction product ?D? and contacting the second solid reaction product ?D? with a reducing agent to form a catalyst component.
Abstract:
The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating PDK1-mediated diseases.