摘要:
Disclosed is the use of benzotropolone derivatives of formula (1), wherein R1, R2 and R7 independently from each other are hydrogen; C1-C3alkyl; or COR8; R3 is hydrogen; or COOR9 R4 is hydrogen; or C1-C3alkyl; R5 is hydrogen; hydroxy; C1-C3-alkoxy; or -0-(CO)-R10; R6 is hydrogen; C1-C3alkyl; or COR8; or R5 and R6 together may form a five or six membered ring; or R6 and R7 together form a five or six membered ring; and R8, R9, R10 independently of each other are C1-C30alkyl; for protecting body-care and household products from photolytic and oxidative degradation.
摘要:
The present invention refers to 5,7-dioxatetracyclo[9.2.1.0 1,9 ,0 4,8 ]tetradecane derivatives of formula I,wherein R 1 - R 3 have the same meaning as given in the description. The invention furthermore refers to their preparation and to perfume compositions and fragrance applications comprising them.
摘要:
A compound of the formula (I) in which the moieties R 1 -R 13 are independently selected from the following moieties: R 1 , R 5 , R 6 , R 8 , R 11 - H, methyl, ethyl, propyl, isopropyl; R 3 - H, methyl, ethyl, propyl, isopropyl, vinyl; R 4 - H, methyl, ethyl; R 2 , R 7 , R 9 - H, methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl, t-butyl; R 10 - H, methyl, ethyl, propyl, isopropyl, t-butyl; R 12 , R 13 - H, C 1-6 linear or branched alkyl; or R 4 and R 11 together with the carbon atoms to which they are attached form a 5- or a 6-membered cycloalkyl ring; or R 6 and R 7 together with the carbon atoms to which they are attached form a cycloalkyl ring having 3, 4, 5 or 6 members. The compounds have strong odours and are useful in fragrances and fragrance applications.
摘要翻译:其中部分R 1〜R 13的式(I)化合物独立地选自下列部分:R 1,R 2, H,甲基,乙基,丙基,异丙基; R 6, H,甲基,乙基,丙基,异丙基,乙烯基; R 4,H,甲基,乙基; R 2,R 7,R 9,H,甲基,乙基,丙基,异丙基,正丁基,异丁基,叔丁基; H,甲基,乙基,丙基,异丙基,叔丁基; R 12,R 13,H,C 1-6直链或支链烷基; 或R 4和R 11与它们所连接的碳原子一起形成5-或6-元环烷基环; 或R 6和R 7与它们所连接的碳原子一起形成具有3,4,5或6个成员的环烷基环。 该化合物具有强烈的气味,可用于香料和香料的应用。
摘要:
Compounds of formula (Ia): wherein R1, R2, R3, R4a, R4b, R5 and R6 are defined herein, as well as other indene derivatives are disclosed herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
摘要:
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions comprising these conjugates. Methods of using these conjugates in the treatment of prostate diseases are also provided.
摘要:
Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
摘要:
Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
摘要:
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions comprising these conjugates. Methods of using these conjugates in the treatment of prostate diseases are also provided.