Abstract:
The invention relates to a cartridge(400), a sensor device, and a method for the optical examination of a sample. A first output light beam that originates from a total internal reflection at a detection surface of a TIR chamber and a second output light beam(L2') that comes from the interior of an inspectable chamber(420) are both received within an observation region(OR). Preferably, these output light beams are detected with the same light detector, e.g. an image sensor. The invention hence allows for observing a total internal reflection at the TIR chamber and for looking into the inspectable chamber(420) from the same observation region(OR). This is for example enabled by different inclinations of the windows encountered by the first and the second output light beams, by different optical elements(407) in the paths of the output light beams, and/or by light scattering surface structures in the inspectable chamber.
Abstract:
Systems and methods for producing an evaporation barrier in a polymerase chain reaction (PCR) vial. Beads with a particular distribution in diameters can be used to produce a barrier for reducing the evaporation of liquid PCR samples within the PCR vial. The beads can be pre-filled in the PCR vial. Liquid samples and/or liquid reagents can be introduced in the PCR vial pre-filled with the beads, such that the beads can be driven to the surface of the liquid PCR sample through the buoyancy of the beads.
Abstract:
Analysesystem zur Analyse einer Körperflüssigkeitsprobe auf einen darin enthaltenen Analyten umfassend ein Testelement (3), das jeweils ein Gehäuse (15) und einen von dem Gehäuse (15) umschlossenen Analysefunktionskanal (16) aufweist, und ein Auswertegerät (2) mit einer Messstation (6) zum Messen einer für das Analyseresultat charakteristischen Messgröße an der Messzone (19) des Testelements (3) und mit einer vorzugsweise rotierbaren Halterung zum Halten eines Testelements (3), wobei das Testelement (3) einen Luftströmungskanal (25) mit zwei Erweiterungsabschnitten (26a, b) und einem zwischen diesen Erweiterungsabschnitten (26a, b) angeordneten engen Abschnitt (27) aufweist, wobei die Erweiterungsabschnitte (26a, b) eine im Vergleich zu dem engen Abschnitt (27) in Richtung von diesem weg zunehmende Querschnittsfläche aufweisen, und ein Verbindungskanal (24) zwischen dem engen Abschnitt (27) und dem Analysefunktionskanal (16) derart angeordnet ist, dass eine Luftaustauschverbindung gebildet wird, der Luftströmungskanal (25) derart angeordnet ist, dass ein mittels einer durch den Luftströmungskanal (25) fließenden Luftströmung erzeugter Unterdruck auf den Analysefunktionskanal (16) wirkt.
Abstract:
A device for fluid assay comprising a carousel (12), mounted about a hub (14), disposed in a complementary shaped housing (16). The carousel (12) is divided into a plurality of chambers (20, 22, 24, 26, 28, 30) disposed radially about the hub (14). The chambers (20, 22, 24, 26, 28, 30) are arranged into pairs which are disposed diametrically opposite one another and which communicate with each other via the hub (14).
Abstract:
In one example, testing cells extend along a length of a slot. Each testing cell includes a microfluidic channel extending from the slot, a pump to move fluid from the slot into the channel, a discharge nozzle through which fluid exits the channel, a fluid discharger to discharge fluid from the channel through the nozzle and a photosensor. A light guide is provided to receive light from an external light source and is to serially transmit the light to the microfluidic channel of each of the plurality of testing cells.
Abstract:
The present invention provides self-contained systems for performing an assay for determining a chemical state, the system including a stationary cartridge for performing the assay therein, at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with said sample to report a result of the assay, wherein the at least one reagent, the sample and the at least one reporter functionality are contained within the cartridge.
Abstract:
A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.
Abstract:
Die vorliegende Erfindung betrifft eine Vorrichtung und ein Verfahren zum Nachweis und zur quantitativen Analyse von Analyten und ihre Verwendung zum Nachweis und zur quantitativen Analyse von Mykotoxinen.
Abstract:
The present invention provides self-contained systems, apparatus and methods for determining a chemical state, the system includes a stationary cartridge for performing the assay therein, the cartridge adapted to house at least one reagent adapted to react with a sample; and at least one reporter functionality adapted to report a reaction of the at least one reagent with the sample to report a result of the assay, a mechanical controller including a first urging means adapted to apply a force externally onto the cartridge to release the at least one reagent; and at least one second urging means adapted to apply a removable force to induce fluidic movement in a first direction in the cartridge and upon removal of the force causing fluidic movement in an opposite direction to the first direction, an optical reader adapted to detect the reaction and a processor adapted to receive data from the optical reader and to process the data to determine said chemical state.