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    AUTOMATED PARTICULATE CONCENTRATION SYSTEM
    1.
    发明申请
    AUTOMATED PARTICULATE CONCENTRATION SYSTEM 审中-公开
    自动颗粒浓缩系统

    公开(公告)号：WO2012118539A2

    公开(公告)日：2012-09-07

    申请号：PCT/US2011/060559

    申请日：2011-11-14

    Applicant: UNIVERSITY OF SOUTH FLORIDA ,  LIM, Daniel V. ,  KEARNS, Elizabeth A. ,  LESKINEN, Stephaney D. ,  MAGANA, Sonia

    Inventor： LIM, Daniel V. ,  KEARNS, Elizabeth A. ,  LESKINEN, Stephaney D. ,  MAGANA, Sonia

    IPC: G01N1/40 ,  C12Q1/02 ,  G01N15/00 ,  G01N33/00

    CPC classification number: G01N1/4077 ,  C02F1/44 ,  C02F2209/001 ,  C02F2209/003 ,  C02F2303/16 ,  G01N2001/4088 ,  Y10T436/143333 ,  Y10T436/20 ,  Y10T436/24 ,  Y10T436/255

    Abstract: An automated system for concentrating potentially harmful substances from various water types or other non-viscous liquids to facilitate detection of those substances is disclosed herein. The automated system comprises a water pressure driven or pump driven concentration unit that filters the test fluid through a hollow-fiber filter. Material collected on the filter is backflushed into a collection vessel by passing a small volume of sterile solution through the filter in the reverse direction. The automated system can be configured to be portable or to be integrated into a continuous liquid stream for online monitoring of test fluids. Optionally, an electronic signal at the end of the backflush sequence triggers a detector, such as an automated array biosensor, to begin processing and analyzing the sample.

    Abstract translation: 本文公开了一种用于从各种水类型或其它非粘性液体中浓缩潜在有害物质以便于检测这些物质的自动化系统。 自动化系统包括水压驱动或泵驱动浓缩单元，其通过中空纤维过滤器对测试流体进行过滤。 将过滤器上收集的材料通过相反的方向通过小量的无菌溶液通过过滤器而被反冲洗成采集容器。 自动化系统可以被配置为便携式的或被集成到连续液体流中以在线监测测试流体。 可选地，在反冲洗序列结束时的电子信号触发诸如自动阵列生物传感器的检测器开始处理和分析样品。

    SEMICONDUCTOR DETECTOR FOR PEROXIDE-BASED EXPLOSIVES
    2.
    发明申请
    SEMICONDUCTOR DETECTOR FOR PEROXIDE-BASED EXPLOSIVES 审中-公开
    用于过氧化物的爆炸物的半导体探测器

    公开(公告)号：WO2010010547A3

    公开(公告)日：2010-03-18

    申请号：PCT/IL2009000477

    申请日：2009-05-12

    Applicant: YEDA RES & DEV ,  NAAMAN RON ,  CAPUA EYAL ,  CAO ROBERTO

    Inventor： NAAMAN RON ,  CAPUA EYAL ,  CAO ROBERTO

    IPC: G01N33/22 ,  G01N27/12

    CPC classification number: G01N27/126 ,  G01N33/0057 ,  Y10T436/142222 ,  Y10T436/143333 ,  Y10T436/16 ,  Y10T436/179228 ,  Y10T436/18 ,  Y10T436/20 ,  Y10T436/202499 ,  Y10T436/203332 ,  Y10T436/204165 ,  Y10T436/204998 ,  Y10T436/205831 ,  Y10T436/206664 ,  Y10T436/207497

    Abstract: A device for the detection of a peroxide-based explosive, in particular, triacetone triperoxide (TATP), which is based on a molecular controlled semiconductor resistor (MOCSER) and composed of at least one insulating or semi-insulating layer, at least one conducting semiconductor layer, two conducting pads and a layer of multifunctional organic molecules capable of adsorbing molecules of said peroxide-based explosive. Further is provided an array of semiconductor devices for the selective detection of a peroxide-based explosive, as well as a method for the selective detection of vapors of a peroxide-based explosive in a gaseous mixture using said array. The multifunctional organic molecules are from the group of cyclodextrins, thiols or alkylphosphonates with RPO (OH) 2 wherein R is an aliphatic hydrocarbyl with C6-C22.

    Abstract translation: 一种用于检测基于过氧化物的炸药，特别是三丙酮三过氧化物（TATP）的装置，其基于分子控制半导体电阻器（MOCSER）并由至少一个绝缘或半绝缘层组成，至少一个导电 半导体层，两个导电焊盘和能够吸附所述基于过氧化物的炸药的分子的多官能有机分子层。 还提供了一种用于选择性检测基于过氧化物的炸药的半导体器件的阵列，以及使用所述阵列选择性地检测气体混合物中基于过氧化物的炸药的蒸气的方法。 多官能有机分子来自具有RPO（OH）2的环糊精，硫醇或烷基膦酸酯基团，其中R是具有C 6 -C 22的脂族烃基。

    DETECTION OF PEROXIDES AND EXPLOSIVES
    3.
    发明申请
    DETECTION OF PEROXIDES AND EXPLOSIVES 审中-公开
    过氧化物和爆炸物的检测

    公开(公告)号：WO2008073173A3

    公开(公告)日：2008-12-31

    申请号：PCT/US2007019248

    申请日：2007-08-31

    Applicant: NOMADICS INC ,  DEANS ROBERT ,  ROSE AIMEE ,  BARDON KEVIN M ,  HANCOCK LAWRENCE F ,  SWAGER TIMOTHY M

    Inventor： DEANS ROBERT ,  ROSE AIMEE ,  BARDON KEVIN M ,  HANCOCK LAWRENCE F ,  SWAGER TIMOTHY M

    IPC: G01N21/77

    CPC classification number: G01N21/76 ,  C07D471/14 ,  G01N21/643 ,  G01N21/783 ,  G01N33/0057 ,  G01N2021/7786 ,  G01N2201/0221 ,  Y10T436/10 ,  Y10T436/20 ,  Y10T436/206664

    Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.

    Abstract translation: 本发明提供了一系列与爆炸物的测定相关的系统，装置和方法，例如过氧化物或过氧化物前体以及其他物质。 本发明的实施方案可以允许怀疑含有爆炸物（例如，过氧化物）或其它物质的样品与反应物相互作用，其中样品可能反应并引起来自反应物的光发射。 本发明的优点可以包括用于确定基于过氧化物的爆炸物的装置的简化，其中装置是便携式的，并且在一些情况下是一次性的。 其他优点可以包括制造和操作的相对容易。

    METHODS OF EMPLOYING VASCULAR LEAKAGE TO DIAGNOSE A CAPILLARY LEAK DISORDER
    4.
    发明申请
    METHODS OF EMPLOYING VASCULAR LEAKAGE TO DIAGNOSE A CAPILLARY LEAK DISORDER 审中-公开
    使用血管漏出诊断毛细血管漏诊的方法

    公开(公告)号：WO2008150870A1

    公开(公告)日：2008-12-11

    申请号：PCT/US2008/065088

    申请日：2008-05-29

    Applicant: SCOTT AND WHITE MEMORIAL HOSPITAL AND SCOTT, SHERWOOD AND BRINDLEY FOUNDATION ,  PUSCHETT, Jules B.

    Inventor： PUSCHETT, Jules B.

    IPC: G01N33/50 ,  A61B5/00

    CPC classification number: G01N33/743 ,  G01N2800/125 ,  G01N2800/26 ,  G01N2800/32 ,  G01N2800/368 ,  Y10T436/20

    Abstract: A method of diagnosing a capillary leak disorder in a patient includes monitoring the marinobufagenin level in blood and/or urine as indicators of vascular permeability and, if a substantial elevation in marinobufagenin exists with respect to that of a normal person, concluding that a capillary leak disorder exists. The method may be employed to diagnose preeclampsia, as well as illnesses or abnormal conditions selected from the group consisting of acute respiratory distress syndrome, hemorrhagic shock, septic, endotoxemia, septicemia, burns.

    Abstract translation: 一种诊断患者毛细血管渗漏障碍的方法包括监测血液和/或尿液中的造血干细胞因子水平，作为血管通透性的指标，如果存在相对于正常人的血浆原核生物素的显着升高，则认为毛细血管渗漏 疾病存在 该方法可用于诊断先兆子痫以及选自急性呼吸窘迫综合征，出血性休克，败血症，内毒素血症，败血病，灼伤的疾病或异常状况。

    SAMPLING DEVICE
    7.
    发明申请
    SAMPLING DEVICE 审中-公开
    采样设备

    公开(公告)号：WO2007129965A1

    公开(公告)日：2007-11-15

    申请号：PCT/SE2007/000451

    申请日：2007-05-08

    Applicant: PROVTAGAREN AB ,  SKARPING, Gunnar ,  DALENE, Marianne

    Inventor： SKARPING, Gunnar ,  DALENE, Marianne

    IPC: G01N1/22 ,  G01N21/78

    CPC classification number: G01N1/2214 ,  G01N21/783 ,  G01N31/22 ,  Y10T436/17 ,  Y10T436/172307 ,  Y10T436/173845 ,  Y10T436/20 ,  Y10T436/21

    Abstract: A sampling device for analysis of a substance which is chosen from the group consisting of isocyanates, aminoisocyanates, amines, and isothiocyanates, and which is present in an air flow intended to pass through the sampling device is disclosed, as well as a method for the production of said sampling device, and a method for the analysis of said substance in the air flow.

    Abstract translation: 公开了一种用于分析选自异氰酸酯，氨基异氰酸酯，胺和异硫氰酸酯并且存在于旨在通过取样装置的空气流中的物质的取样装置，以及一种用于 所述采样装置的生产，以及用于分析空气流中所述物质的方法。

    NITRIC OXIDE DETECTION
    8.
    发明申请
    NITRIC OXIDE DETECTION 审中-公开
    氮氧化物检测

    公开(公告)号：WO2007029164A3

    公开(公告)日：2007-10-11

    申请号：PCT/IB2006053095

    申请日：2006-09-04

    Applicant: KONINKL PHILIPS ELECTRONICS NV ,  BURDINSKI DIRK

    Inventor： BURDINSKI DIRK

    IPC: G01N33/00 ,  G01N33/497

    CPC classification number: G01N33/0037 ,  Y02A50/245 ,  Y10T436/173076 ,  Y10T436/177692 ,  Y10T436/20 ,  Y10T436/204165

    Abstract: The present invention relates to a method for amplifying the detected signal in a gas sensor. More specifically, the present invention relates to a method for increasing the concentration of the gas which is being detected in a sample or increasing the concentration of a gas which is directly obtained from the gas in the sample by chemical reaction. The gas which is to be detected is nitric oxide (NO). In particular, the method concerns the selective conversion of NO to NO2 which allows a threefold amplification of the number of analyte molecules in NO trace gas analysis in a single amplification cycle. Subsequent reduction or thermal decomposition of the obtained NO2 can provide NO again, which can again be introduced in a new amplification cycle. Multiple (n) amplification cycles can provide a sensitivity amplification by a factor 3 n . The method can be combined with a multitude of detection methods and tolerates a high humidity. The method is therefore of general use in the analysis of NO from a variety of sources.

    Abstract translation: 本发明涉及一种在气体传感器中放大检测信号的方法。 更具体地说，本发明涉及一种提高样品中检测的气体浓度的方法，或通过化学反应增加直接从样品中的气体获得的气体的浓度。 要检测的气体是一氧化氮（NO）。 特别地，该方法涉及NO向NO 2的选择性转化，其允许在单个放大循环中在NO痕量气体分析中分析物分子数量的三倍放大。 所得到的NO 2的还原或热分解可以再次提供NO，这可以再次在新的扩增循环中引入。 多个（n）个放大循环可以通过因子3进行灵敏度放大。 该方法可以与多种检测方法相结合，并能承受高湿度。 因此，该方法通常用于分析来自各种来源的NO。

    DETECTION SYSTEMS AND DOPANTS
    10.
    发明申请
    DETECTION SYSTEMS AND DOPANTS 审中-公开
    检测系统和DOPANTS

    公开(公告)号：WO2006123107A1

    公开(公告)日：2006-11-23

    申请号：PCT/GB2006/001739

    申请日：2006-05-12

    Applicant: SMITHS GROUP PLC ,  WYNN, Paul, Grant ,  MCINTYRE, Henry, Paul

    Inventor： WYNN, Paul, Grant ,  MCINTYRE, Henry, Paul

    IPC: H01J49/40

    CPC classification number: G01N27/622 ,  Y10T436/13 ,  Y10T436/17 ,  Y10T436/20 ,  Y10T436/202499 ,  Y10T436/24 ,  Y10T436/25875

    Abstract: An ion mobility spectrometer has a drift chamber (1) with an inlet (2) at one end by which a gas or vapour being analysed is supplied to the chamber. After ionization, molecules are admitted through a gate 8 and flow along a drift region (9) to a collector plate (11). A drift gas is flowed through the drift region against the flow of ionized molecules and is circulated along a flow path (31, 32, 40) and (30), which includes a chamber (50) including a dopant. The dopant is 2,4-pentanedione, which has been found to enhance the detection of a number of compounds especially toxic industrial chemicals and nitrogen compounds, such as those present in the breath of mammals.

    Abstract translation: 离子迁移谱仪具有在一端具有入口（2）的漂移室（1），通过该入口将所分析的气体或蒸汽供应到室。 电离后，分子通过栅极8进入，并沿着漂移区（9）流到集电板（11）。 漂移气体抵抗离子化分子的流动流过漂移区，并且沿着包括包含掺杂剂的室（50）的流动路径（31,32,40）和（30）循环。 掺杂剂是2,4-戊二酮，已经被发现增强了许多化合物的检测，特别是有毒的工业化学品和氮化合物，例如存在于哺乳动物呼吸中的化合物。

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