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41.发明公开THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE 审中-公开治疗性多肽，编码这些NUKLEINSAÜRE和使用方法
公开(公告)号：EP1549671A2
公开(公告)日：2005-07-06
申请号：EP03726154.2
申请日：2003-04-01
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P. II , BENTO, Patricia , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CRABTREE-BOKOR, Julie, R. , EDINGER, Shlomit, R. , ELLERMAN, Karen , FERNANDES, Elma, R. , GERLACH, Valerie, L. , GROSSE, William M. , GUNTHER, Erik , GUSEV, Vladimir, Y. , HEYES, Melvyn, P. , LEPLEY, Denise, M. , LI, Li , MACDOUGALL, John, R. , MALYANKAR, Uriel, M. , MILLET, Isabelle , PATTURAJAN, Meera , PEYMAN, John A. , RASTELLI, Luca , RIEGER, Daniel K. , SHENOY, Suresh G. , SHIMKETS, Richard D. , SMITHSON, Glennda , STONE, David J. , VERNET, Corine A.M. , VOSS, Edward Z.
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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42.发明公开THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING THE SAME, AND METHODS OF USE 审中-公开治疗性多肽，编码该核酸的核酸及使用方法
公开(公告)号：EP1539806A2
公开(公告)日：2005-06-15
申请号：EP02741692.4
申请日：2002-05-02
申请人： Curagen Corporation
发明人： ALSOBROOK, John P. II , ANDERSON, David W. , BOLDOG, Ferenc L. , BURGESS, Catherine E. , CASMAN, Stacie J. , EDINGER, Schlomit R. , ELLERMAN, Karen , GANGOLLI, Esha A. , GERLACH, Valerie L. , GORMAN, Linda , GUNTHER, Erik , HERRMANN, John L. , JI, Weizhen , LEPLEY, Denise M. , LEWIN, David A. , LI, Li , MACDOUGALL, John R. , MALYANKAR, Uriel M. , MEZES, Peter D. , PADIGARU, Muralidhara , PATTURAJAN, Meera , PEYMAN, John A. , RASTELLI, Luca , RIEGER, Daniel K. , ROTHENBERG, Mark E. , SHENOY, Suresh G. , SMITHSON, Glennda , SPYTEK, Kimberly A. , STONE, David J. , TAUPIER, Raymond J., Jr. , TCHERNEV, Velizar T. , VERNET, Corine A. M. , VOSS, Edward Z. , ZERHUSEN, Bryan D. , ZHONG, Haihong , MILLER, Charles E.
CPC分类号： C07K14/705 , C07K14/47
摘要： Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the-polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
摘要翻译： 本文公开了编码G偶联蛋白质受体相关多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及与多肽免疫特异性结合的抗体，以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明进一步公开了用于诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。
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43.发明公开
公开(公告)号：EP1504026A2
公开(公告)日：2005-02-09
申请号：EP02794126.9
申请日：2002-12-03
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CHILLAKURU, Rajeev, A. , EDINGER, Shlomit, R. , GERLACH, Valerie, L. , GORMAN, Linda , GOULD-ROTHBERG, Bonnie, E. , GUO, Xiaojia , JEFFERS, Michael, E. , JI, Weizhen , LI, Li , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MURPHEY, Ryan , PATTURAJAN, Meera , PEYMAN, John, A. , RASTELLI, Luca , SHENOY, Suresh, G. , SMITHSON, Glennda , RIEGER, Daniel K. , STARLING, Gary , TAUPIER, Raymond J.Jr. , VOSS, Edward Z. , ZHONG, Haihong , ZHONG, Mei
IPC分类号： C07K14/435
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
摘要翻译： 本文公开了编码新多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体，以及对多肽特异的新多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 还包括载体，宿主细胞，抗体和用于产生多肽和多核苷酸的重组方法，以及使用它们的方法。 本发明进一步公开了用于诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。
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44.发明公开NOVEL ANTIBODIES THAT BIND TO ANTIGENIC POLYPEPTIDES,NUCLEIC ACIDS ENCODINGS THE ANTIGENS, AND METHODES OF USE 审中-公开新抗原多肽结合的抗体ANTI编码基因NUCLEIC和使用方法
公开(公告)号：EP1463747A2
公开(公告)日：2004-10-06
申请号：EP02741693.2
申请日：2002-05-02
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , CHAPOVAL, Andrei , EDINGER, Schlomit , GERLACH, Valerie , GORMAN, Linda , GUNTHER, Erik , GUO, Xiaojia , KEKUDA, Ramesh , LEPLEY, Denise, M. , LI, Li , LIU, Xiaohong , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MILLET, Isabelle , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol E.A. , RIEGER, Daniel K. , SHENOY, Suresh g. , SHIMKETS, Richard A. , SPYTEK, Kimberly A. , TAUPIER, Raymond J., Jr. , VERNET, Corine A.M. , VOSS, Edward Z. , ZERHUSEN, Bryan D.
CPC分类号： C07K14/47 , A61K38/00 , C07K14/705
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
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公开(公告)号：EP1409536A2
公开(公告)日：2004-04-21
申请号：EP02765832.7
申请日：2002-02-12
申请人： Curagen Corporation
发明人： GUO, Xiaojia , FERNANDES, Elma , LI, Li , KEKUDA, Ramesh , LIU, Yi , LEITE, Mario , SPYTEK, Kimberly, A. , JI, Weizhen , CASMAN, Stacie J. , BOLDOG, Ference L. , PATTURAJAN, Meera , VERNET, Corine A.M. , BALLINGER, Robert, A. , MALYANKAR, Uriel, M. , TCHERNEV, Velizar, T. , BLALOCK, Angela, D. , GUSEV, Vladimir, Y. , RASTELLI, Luca , MEZES, Peter, D. , ELLERMAN, Karen , HEYES, Melvyn , HERRMANN, John L. , SHIMKETS, Richard A. , IOIME, Noelle , PENA, Carel E.A. , SHENOY, Suresh G. , TAUPIER, Raymond J., Jr. , GERLACH, Valerie , GORMAN, Linda
IPC分类号： C07K14/47 , C12N15/12 , C07K16/18 , G01N33/53 , C12Q1/68 , G01N33/50 , A61K38/17 , A61K31/7088 , A61K39/395
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving anyone of these novel human nucleic acids and proteins.
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46.发明公开HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME 审中-公开人类蛋白质，多核苷酸编码它们及其使用方法
公开(公告)号：EP1407018A2
公开(公告)日：2004-04-14
申请号：EP01993355.5
申请日：2001-10-26
申请人： Curagen Corporation
发明人： GANGOLLI, Esha, A. , SPYTEK, Kimberly, A. , GILBERT, Jennifer , CASMAN, Stacie , BLALOCK, Angela , LI, Li , VERNET, Corine, A., M. , SHENOY, Suresh , MISHRA, Vishnu , FURTAK, Katarzyna , GERLACH, Valerie , EDINGER, Shlomit , MALYANKAR, Uriel , STONE, David , MILLET, Isabelle , SMITHSON, Glennda , GUNTHER, Erik , PADIGARU, Muralidhara , TAUPIER, Raymond, J., Jr. , ANDERSON, David , ELLERMAN, Karen
IPC分类号： C12N15/12 , C07K14/47 , C07K16/18 , G01N33/53 , C12Q1/68 , G01N33/50 , A61K39/395 , A61K31/7088 , A61K38/17
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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47.发明公开NOVEL ANTIBODIES THAT BIND TO ANTIGENIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING THE ANTIGENS, AND METHODS OF USE 审中-公开新抗体的抗基因多肽结合抗基因编码核酸及使用方法
公开(公告)号：EP1401470A2
公开(公告)日：2004-03-31
申请号：EP02732027.4
申请日：2002-06-04
申请人： Curagen Corporation
发明人： ANDERSON, David, W. , ZERHUSEN, Bryan, D. , LI, Li , ZHONG, Mei , CASMAN, Stacie, J. , GERLACH, Valerie, L. , SHIMKETS, Richard, A. , GORMAN, Linda , PENA, Carol, E., A. , KEKUDA, Ramesh , PATTURAJAN, Meera , SPYTEK, Kimberly, A. , LEITE, Mario, W. , RASTELLI, Luca , MACDOUGALL, John, R. , TAUPIER, Raymond, J., Jr. , GUO, Xiaojia , MILLER, Charles, E. , SHENOY, Suresh, G. , HJALT, Tord , VOSS, Edward Z. , BOLDOG, Ferenc L. , MALYANKAR, Uriel M. , PADIGARU, Muralidhara , JI, Weizhen , SMITHSON, Glennda , EDINGER, Shlomit R. , MILLET, Isabelle , ELLERMAN, Karen
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
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48.发明公开
公开(公告)号：EP1379554A2
公开(公告)日：2004-01-14
申请号：EP02739088.9
申请日：2002-02-21
申请人： Curagen Corporation
发明人： PENA, Carol, E., A. , SHIMKETS, Richard, A. , LI, Li , SHENOY, Suresh, G. , KEKUDA, Ramesh , SPYTEK, Kimberly, A. , VERNET, Corine, A., M. , MALYANKAR, Uriel, L. , GUO, Xiaojia , GUSEV, Vladimir, Y. , CASMAN, Stacie, J. , BOLDOG, Ferenc, L. , FURTAK, Katarzyna , TCHERNEV, Velizar, T. , PATTURAJAN, Meera , GANGOLLI, Esha, A. , PADIGARU, Muralidhara , LIU, Xiaohong , BAUMGARTNER, Jason, C. , GERLACH, Valerie L. , SPADERNA, Steven K. , ZERHUSEN, Bryan D.
IPC分类号： C07K14/47 , C12N15/12 , C12N5/10 , C07K16/18 , G01N33/53 , G01N33/50 , A61K48/00 , A61K31/713
CPC分类号： G05B19/408 , A61K31/713 , A61K38/00 , A61K48/00 , C07K14/47
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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49.发明公开HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME 审中-公开人类蛋白质，多核苷酸编码它们的和使用方法
公开(公告)号：EP1356047A2
公开(公告)日：2003-10-29
申请号：EP01989235.5
申请日：2001-12-17
申请人： Curagen Corporation
发明人： SHIMKETS, Richard, A. , COLMAN, Steven, D. , SPYTEK, Kimberly, A. , BALLINGER, Robert, A. , GUO, Xiaojia , TCHERNEV, Velizar, T. , SHENOY, Suresh, G. , LI, Li , ELLERMAN, Karen, E. , ZERHUSEN, Bryan, D. , PATTURAJAN, Meera , CASMAN, Stacie, J. , BOLDOG, Ferenc , GUSEV, Vladimir, Y. , BURGESS, Catherine, E. , EDINGER, Schlomit , GANGOLLI, Esha, A. , MALYANKAR, Uriel, M. , GUNTHER, Erik , SMITHSON, Glennda , MILLET, Isabelle , GERLACH, Valerie L.
IPC分类号： C12N15/12 , C07K14/47 , C07K14/705 , C07K14/485 , C07K14/81 , C12N9/02 , C07K16/18 , G01N33/53 , G01N33/68 , A61K38/17 , A61K39/00 , C12Q1/68
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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50.发明公开HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME 审中-公开人类蛋白质，多核苷酸编码它们及其使用方法
公开(公告)号：EP1349930A2
公开(公告)日：2003-10-08
申请号：EP01977537.8
申请日：2001-10-05
申请人： Curagen Corporation
发明人： SHIMKETS, Richard, A. , TAUPIER, Raymond, J., Jr. , BURGESS, Catherine, E. , ZERHUSEN, Bryan, D. , MEZES, Peter, S. , RASTELLI, Luca , MALYANKAR, Uriel, M. , GROSSE, William, M. , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , SPYTEK, Kimberly, Ann , LI, Li , EDINGER, Shlomit , GERLACH, Valerie , ELLERMAN, Karen , MACDOUGALL, John , GUNTHER, Erik , MILLET, Isabelle , STONE, David , SMITHSON, Glennda , SZEKERES, Edward S., Jr.
IPC分类号： C12N15/12 , C07K14/47 , C07K14/475 , C07K14/705 , C12N15/63 , C12N1/21 , C12N5/10 , C12Q1/68 , G01N33/68
CPC分类号： C12Q1/6883 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K14/47 , C12Q2600/156 , C12Q2600/158
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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