公开(公告)号：EP0756633B1

公开(公告)日：2005-06-08

申请号：EP95915003.8

申请日：1995-04-03

申请人： Integrated Research Technology, LLC

发明人： THORNTON, Charles, G.

IPC分类号： C12Q1/00 ,  C12Q1/06

CPC分类号： C12Q1/689 ,  C12Q1/6806 ,  G01N33/5695 ,  Y10S435/863 ,  Y10S435/864 ,  Y10S435/865 ,  Y10S435/866 ,  Y10S435/975 ,  Y10S514/852 ,  Y10S514/863 ,  Y10S514/864

公开(公告)号：EP0608433B1

公开(公告)日：2004-05-19

申请号：EP93914997.7

申请日：1993-07-13

申请人： SHISEIDO COMPANY, LTD.

发明人： YANAGIDA, Takeshi The Shiseido Research Center ,  SAKAMOTO, Okihiko The Shiseido Research Center

IPC分类号： A61K7/00 ,  A61K7/48

CPC分类号： A61K8/738 ,  A61K8/671 ,  A61K31/07 ,  A61K45/06 ,  A61K47/6951 ,  A61K2800/51 ,  A61K2800/52 ,  A61K2800/522 ,  A61K2800/56 ,  A61Q1/06 ,  A61Q19/00 ,  A61Q19/08 ,  B82Y5/00 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/864 ,  Y10S514/88 ,  A61K2300/00

摘要： An external skin treatment composition containing (I) vitamin A (retinol) and (II) as a stabilizer, an oil, polyethylene (propylene) glycol, a hydroxy carboxylate, a neutral amino acid salt, an oil-soluble antioxidant/EDTA/a benzophenone compound, an oil-soluble antioxidant/an acid/a benzophenone compound, an inclusion compound of cyclodextrin including an antioxidant and/or an ultraviolet absorber, butanediol and/or an oil-soluble antioxidant, a water-soluble benzophenone compound, a basic amino acid and the salt thereof, an acidic amino acid and the salt thereof, a polar oil, a water-swellable clay mineral.

公开(公告)号：EP1300138A3

公开(公告)日：2003-05-28

申请号：EP02025465.2

申请日：1995-12-12

申请人： Beiersdorf AG

发明人： Untiedt, Sven, Dr. ,  Stäb, Franz ,  Lanzendörfer, Ghita

IPC分类号： A61K7/48 ,  A61K7/42 ,  A61K31/70

CPC分类号： A61Q19/00 ,  A61K8/36 ,  A61K8/361 ,  A61K8/365 ,  A61K8/37 ,  A61K8/498 ,  A61K8/602 ,  A61K8/97 ,  A61K31/19 ,  A61K31/192 ,  A61K31/70 ,  A61K45/06 ,  A61K2800/522 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/001 ,  A61Q19/08 ,  Y10S514/858 ,  Y10S514/859 ,  Y10S514/86 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/864 ,  Y10T428/193 ,  Y10T428/195 ,  A61K2300/00

摘要： Gegenstand der Erfindung ist die Verwendung von a) einer Verbindung oder mehrerer Verbindungen aus der Gruppe der Flavonoide oder b) einer Wirkstoffkombination, enthaltend eine Verbindung oder mehrere Verbindungen, ausgewählt aus der Gruppe der Flavonoide in Kombination mit einer Verbindung oder mehreren Verbindungen, ausgewählt aus der Gruppe der Zimtsäurederivate, und gegebenenfalls zusätzlich jeweils einer Verbindung oder mehreren Verbindungen aus einer der Gruppen oder mehreren der Gruppen c) der Antioxidantien oder d) der endogenen Energiestoffwechselmetaboliten oder e) der endogenen enzymatischen Antioxydansysteme und deren synthetischen Derivaten (Mimics) oder f) der antimikrobiellen Wirksysteme oder g) der antiviralen Wirksysteme oder h) Wirkstoffen der bekannten, konventionellen Behandlungsformen jeweils zur Behandlung oder prophylaktischen Behandlung von hyperreaktiver und für Dermatiden prädisponierter Haut oder defizitärer, hypoaktiver Haut oder Dermatosen.

公开(公告)号：EP1250116A1

公开(公告)日：2002-10-23

申请号：EP01900239.3

申请日：2001-01-10

申请人： Thixo Ltd.

发明人： EINI, Meir ,  TAMARKIN, Dov

IPC分类号： A61K7/00 ,  A61K9/00 ,  A61K9/06 ,  A61K9/08 ,  A61K9/10 ,  A61K9/70 ,  A61K47/00 ,  A61K47/02 ,  A61K47/10

CPC分类号： A21D2/14 ,  A21D2/16 ,  A23C9/1315 ,  A23C11/04 ,  A23C13/12 ,  A23C15/16 ,  A23C19/055 ,  A23C19/093 ,  A23D7/0053 ,  A23D7/0056 ,  A23D7/011 ,  A23D7/013 ,  A23D9/007 ,  A23G1/305 ,  A23G1/36 ,  A23G1/38 ,  A23G3/346 ,  A23G2200/08 ,  A23J3/227 ,  A23L7/109 ,  A23L7/122 ,  A23L7/183 ,  A23L13/43 ,  A23L19/18 ,  A23L23/10 ,  A23L33/115 ,  A23P20/11 ,  A61K8/342 ,  A61K8/922 ,  A61K9/0014 ,  A61K9/0048 ,  A61K31/225 ,  A61K31/351 ,  A61K31/43 ,  A61K31/496 ,  A61K31/545 ,  A61K31/573 ,  A61K31/65 ,  A61K36/738 ,  A61K36/899 ,  A61K45/06 ,  A61K47/06 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/44 ,  A61Q19/00 ,  Y10S514/863 ,  Y10S514/864 ,  A61K2300/00

摘要： A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.

公开(公告)号：EP1206269A1

公开(公告)日：2002-05-22

申请号：EP00946975.0

申请日：2000-06-30

申请人： Girvan, Don H.

发明人： Girvan, Don H.

IPC分类号： A61K33/22

CPC分类号： A61K45/06 ,  A61K33/22 ,  Y10S514/825 ,  Y10S514/826 ,  Y10S514/827 ,  Y10S514/828 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/858 ,  Y10S514/859 ,  Y10S514/86 ,  Y10S514/861 ,  Y10S514/862 ,  Y10S514/863 ,  Y10S514/864 ,  Y10S514/865 ,  Y10S514/871 ,  Y10S514/886 ,  Y10S514/887 ,  Y10S514/928 ,  A61K2300/00

摘要： The present invention is directed to methods and compositions for treating skin disorders. The present invention is easily administered and can be used for both humans and animals. The compositions of the present invention comprise borate compounds and provide relief from skin disorder symptoms and lesions. Additionally, the present invention can be used to provide long term maintenance of symptom-free skin.

公开(公告)号：EP1005345A4

公开(公告)日：2002-01-16

申请号：EP98909996

申请日：1998-02-10

申请人： SEPRACOR INC

发明人： HANDLEY DEAN A ,  RUBIN PAUL D

IPC分类号： A61K31/445 ,  A61K31/4545 ,  A61K45/06 ,  A61P11/06 ,  A61P37/08 ,  A61P43/00

CPC分类号： A61K45/06 ,  A61K31/445 ,  A61K31/4545 ,  Y10S514/826 ,  Y10S514/864

摘要： Methods utilizing descarboethoxyloratadine ("DCL"), for the treatment of allergic disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. Also included are methods for the treatment of allergic asthma using DCL and either a decongestant or a leukotriene inhibitor, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. The invention also encompasses the administration of DCL in a nasal or oral spray.

公开(公告)号：EP1128812A1

公开(公告)日：2001-09-05

申请号：EP99955981.8

申请日：1999-11-12

申请人： Asat AG Applied Science & Technology

发明人： Schmid, Hans W. ,  Burmeister, Gerd

IPC分类号： A61K9/107 ,  A61K31/197 ,  A61K41/00 ,  A61P35/00 ,  A61P17/06

CPC分类号： A61K49/0021 ,  A61K9/1075 ,  A61K31/197 ,  A61K41/0061 ,  Y10S514/863 ,  Y10S514/864

摘要： The present invention relates to a composition comprising a nano-emulsion that contains 5-aminolevulinic acid as well as a carrier in an aqueous phase. This invention also relates to a pharmaceutical preparation containing this composition. The nano-emulsions of this type can be used in photodynamic therapy as well as in the photodiagnostic detection of proliferative cells.

公开(公告)号：EP1024792A4

公开(公告)日：2001-08-08

申请号：EP98951104

申请日：1998-10-19

申请人： SOLTEC RES PTY LTD

发明人： DAVEY GREG ,  ABRAM ALBERT ZORKO

IPC分类号： A23L27/20 ,  A61K8/00 ,  A61K8/04 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/36 ,  A61K8/368 ,  A61K8/40 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/60 ,  A61K9/12 ,  A61K31/085 ,  A61K31/135 ,  A61K31/19 ,  A61K31/192 ,  A61K31/27 ,  A61K31/343 ,  A61K31/4196 ,  A61K31/496 ,  A61K31/513 ,  A61K31/7048 ,  A61K45/00 ,  A61K47/10 ,  A61K47/18 ,  A61P31/10 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/00 ,  A61K7/00 ,  A61K7/48

CPC分类号： A61K8/046 ,  A61K8/33 ,  A61K8/345 ,  A61K8/36 ,  A61K8/361 ,  A61K8/368 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4946 ,  A61K8/4953 ,  A61K8/4973 ,  A61K8/602 ,  A61K9/0014 ,  A61K9/122 ,  A61K31/496 ,  A61K47/10 ,  A61K47/186 ,  A61Q5/006 ,  Y10S514/863 ,  Y10S514/864 ,  Y10S514/945 ,  Y10S514/947

摘要： The invention relates to a topical, foamable composition including at least one antifungal agent, said composition characterised in that said at least one antifungal agent is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and in that it has a residual non-volatile component content of less than 25 %. The invention furthermore relates to a method of treating fungal diseases including jock itch, tinea, dandruff and sebborheic dermatitis by applying to the affected area of a patient requiring such treatment the antifungal composition as claimed in any one of claims 1-29.

摘要翻译： 本发明涉及一种局部的，可发泡组合物包括至少一种抗真菌剂，所述组合物其特征在于，所述至少一种抗真菌剂是能够穿透皮肤的上层和被保持在或上的区域在延长的待处理 一段时间，并且其残留的不挥发性组分含量小于25％。 本发明还涉及治疗真菌疾病，包括股癣，足癣，头皮屑和sebborheic皮炎通过向需要这种治疗的抗真菌组合物如权利要求1-29中任一项所述的患者的受影响区域的方法。

公开(公告)号：EP1009379A1

公开(公告)日：2000-06-21

申请号：EP98942793.5

申请日：1998-08-27

申请人： L'OREAL

发明人： BRETON, Lionel ,  DE LACHARRIERE, Olivier ,  NONOTTE, Isabelle

IPC分类号： A61K7/48 ,  A61K31/195 ,  A61K31/55

CPC分类号： A61K31/5513 ,  A61K8/44 ,  A61K8/466 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4953 ,  A61K8/63 ,  A61K31/197 ,  A61K31/198 ,  A61K31/4406 ,  A61K31/506 ,  A61Q19/00 ,  A61Q19/005 ,  Y10S514/864 ,  Y10S514/887

摘要： The invention concerns the use of one or several substances agonists of one or several receptors associated with a chlorine canal or a potassium canal in a cosmetic and/or dermatological composition, for treating sensitive skins and more particularly for eliminating itching, pruritus, stabbing pains, tingling and/or erythema. The agonist substance is in particular taurine, gamma-aminobutyric (GABA), isoguvacin, isonipecotic acid, 4,5,6,7-tetrahydroisoazolo-(5,4-c)pyridin-3(2H)-one, benzodiazepines, steroids, cromakalim, pinacidil, nicorandil and minoxidil.

公开(公告)号：EP0986537A2

公开(公告)日：2000-03-22

申请号：EP99910451.6

申请日：1999-03-29

申请人： Galderma Research & Development, S.N.C.

发明人： DIAZ, Philippe ,  BERNARDON, Jean-Michel

IPC分类号： C07C391/02

CPC分类号： C07C323/54 ,  C07C391/02 ,  Y10S514/824 ,  Y10S514/825 ,  Y10S514/859 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/864 ,  Y10S514/866 ,  Y10S514/88 ,  Y10S514/885 ,  Y10S514/886 ,  Y10S514/887 ,  Y10S514/902 ,  Y10S514/909 ,  Y10S514/912

摘要： The invention concerns novel heteroethynylene compounds of general formula (I) and their use in pharmaceutical compositions for use in human or veterinary medicine (dermatologic, rheumatic, respiratory, cardiovascular and ophthalmologic affections in particular), or for cosmetic compositions.