中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

134 records (took 0.02 seconds)

    BIOSENSOR DEVICE
    61.
    发明公开
    BIOSENSOR DEVICE 审中-公开
    生物传感器装置

    公开(公告)号：EP2081011A1

    公开(公告)日：2009-07-22

    申请号：EP07807764.1

    申请日：2007-09-21

    Applicant: Fujifilm Corporation

    Inventor： OGURA, Nobuhiko

    IPC: G01N21/27

    CPC classification number: G01N21/253 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: Improving processing power of a biosensor detection apparatus for measurement while preventing structural complication and size increase in the apparatus. Providing one or more spectrometers (20) configured to spectrally separate each light beam (Lr) reflected from each of a plurality of measurement regions defined on a biosensor (10) simultaneously and one or more optical receivers (30) configured to receive each light beam (Ls) spectrally separated by the one or more spectrometers (20) simultaneously, thereby enabling the apparatus to obtain a spectral intensity distribution of each light beam (Ls) separately.

    Abstract translation: 提高测定用生物传感器检测装置的处理能力，同时防止装置中的结构复杂化和尺寸增加。 提供被配置为谱线分离的各光束（LR）的一个或更多个光谱仪（20）从每个对被配置为接收各个光束的生物传感器（10），同时和一个或多个光接收器（30）定义的多个测量区域的反射 （Ls）同时被所述一个或多个光谱仪（20）光谱分离，由此使得所述设备能够分别获得每个光束（Ls）的光谱强度分布。

    MODIFICATION OF THE NORMALIZED DIFFERENCE METHOD FOR REAL-TIME OPTICAL TOMOGRAPHY
    66.
    发明公开
    MODIFICATION OF THE NORMALIZED DIFFERENCE METHOD FOR REAL-TIME OPTICAL TOMOGRAPHY 审中-公开
    为实时光学层析成像的归一化差的方法的变形例

    公开(公告)号：EP1493123A1

    公开(公告)日：2005-01-05

    申请号：EP03717000.8

    申请日：2003-04-07

    Applicant: Barbour, Randall L. ,  Pei, Yaling

    Inventor： Barbour, Randall L. ,  Pei, Yaling

    IPC: G06K9/00

    CPC classification number: G06T11/006 ,  A61B5/0073 ,  A61B5/0091 ,  A61B5/4312 ,  G01N21/359 ,  G01N21/4795 ,  G01N21/49 ,  G01N2021/1787 ,  G01N2021/475 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: Computation -saving techniques and stability-adding techniques provide for fast, accurate reconstructions of a time series of images involving large scale 3D problems, such as real-time image recovery in an optical tomography imaging system. A system equation for a target medium (116) such as a tissue is solved using a Normalized Difference Method (NDM) (250). Because of the inherent stability of the NDM solutions, a weight matrix (W) of the system equation can be provided for a given point in a time series (220), then reused without recalculation at subsequent points. Further saving are achieved by decomposing W using singular value decomposition or direst matrix decomposition, transforming it to reduce its dimensions, and/or scaling it to achieve a more stable numerical solution. Values of measured energy (112) emerging from the target medium are back-substituted into the system equation for the different points to obtain the target medium properties.

    FLUORESCENCE SENSING DEVICE
    67.
    发明授权
    FLUORESCENCE SENSING DEVICE 失效
    DEVICE荧光检测

    公开(公告)号：EP0981734B1

    公开(公告)日：2003-07-30

    申请号：EP98922205.4

    申请日：1998-05-12

    Applicant: Colvin, Arthur E., Jr.

    Inventor： Colvin, Arthur E., Jr.

    IPC: G01N21/64 ,  G01N21/77

    CPC classification number: G01N21/6454 ,  G01N21/6428 ,  G01N21/7703 ,  G01N2021/6484 ,  G01N2201/0833

    Abstract: A fluorescence sensing device for determining the presence or concentration of an analyte in a liquid or gaseous medium is constructed of a fiber optic plate (12) comprising optical fibers having relatively small numerical apertures. The fiber optic plate is positioned on a photodetector and has a layer of analyte-permeable fluorescent matrix (22) or coated waveguide material on its top surface. The fluorescent matrix or waveguide coating contains indicator molecules whose fluorescence is affected by the local presence of analyte. A light source emits light into the fluorescent matrix in a direction generally parallel to the top surface of the fiber optic plate. Upon absorbing light from the light source, indicator molecules in the fluorescent matrix emit fluorescent light which is transmitted through the fiber optic plate to the photodetector.

    METHOD AND DEVICE FOR MEASURING CAVITATION
    68.
    发明公开
    METHOD AND DEVICE FOR MEASURING CAVITATION 审中-公开
    方法和设备测量CAVITATION

    公开(公告)号：EP1317806A1

    公开(公告)日：2003-06-11

    申请号：EP01958904.3

    申请日：2001-07-10

    Applicant: L-Tech Corporation

    Inventor： FERRELL, Gary, W.

    IPC: H04B17/00 ,  G01N29/02

    CPC classification number: G01N21/8507 ,  G01N21/1702 ,  G01N21/70 ,  G01N2021/8411 ,  G01N2201/0833 ,  H01L21/67028

    Abstract: A method, probe (14) and system for detecting presence of cavitation in a liquid and measuring cavitation density and intensity of a specific locale in the fluid. A first cavitation void (11-1 ) and associated energy perturbation, produced in a first liquid (L1), moves within the first liquid (L1) and is received at a very thin plate (13), which separates the first liquid (L1) from a second liquid (L2) and is part of a light-proof chamber (15) containing the second liquid (L2). An energy perturbation in the first liquid (L1) is received at the thin plate (13) and produces at least one cavitation void or associated energy perturbation (11-1 ) in the second liquid (L2); and the energy perturbation in the second liquid (L2) is eventually converted into an electromagnetic signal. This signal is received by a photomultiplier (19) and converted to an electronic signal that indicates the presence of cavitation. The system can distinguish between cavitation voids produced at one location and/or time interval and voids produced at another location and/or another time interval.

    IMAGING SYSTEM FOR LUMINESCENCE ASSAYS
    69.
    发明公开
    IMAGING SYSTEM FOR LUMINESCENCE ASSAYS 有权
    图片SYSTEM FOR发光分析

    公开(公告)号：EP1099107A1

    公开(公告)日：2001-05-16

    申请号：EP99934902.0

    申请日：1999-07-20

    Applicant: PACKARD INSTRUMENT COMPANY

    Inventor： RUSHBROOKE, John Gordon ,  HOOPER, Claire, Elizabeth

    IPC: G01N21/64

    CPC classification number: G01N21/6452 ,  G01N21/76 ,  G01N2021/6421 ,  G01N2021/6484 ,  G01N2201/0826 ,  G01N2201/0833 ,  G01N2201/0866

    Abstract: Apparatus for detecting light emitted by assay samples is provided, in which light emitted by the sample is collected for transmission to a charge coupled device camera (74) by an optical fibre bundle. The cross-sectional area of the optical fibre bundle corresponds to the area of the sample, the end of which is located close to the sample for detecting any light emitted therefrom, and selected fibres (30) of those making up the bundle are separated from the remainder and extend to a source of excitation radiation (76) and serve to convey excitation radiation (if required) directly to a corresponding plurality of points distributed over the area of the end face of the bundle and therefore over the area of the sample. The remaining fibres (32, 38) of the bundle serve to collect emitted light (whether generated by fluorescence caused by excitation or otherwise) and provide a light path to the charge coupled device camera, wherein the ends of the excitation fibres and the ends of the emitted light collecting fibres are distributed uniformly over the area of the fibre bundle presented to the reaction site.

    HIGH DENSITY ARRAY FABRICATION AND READOUT METHOD FOR A FIBER OPTIC BIOSENSOR
    70.
    发明公开
    HIGH DENSITY ARRAY FABRICATION AND READOUT METHOD FOR A FIBER OPTIC BIOSENSOR 失效
    准备再现为一个光纤生物传感器的高密度的Martix，以及方法

    公开(公告)号：EP0879299A1

    公开(公告)日：1998-11-25

    申请号：EP97903922.0

    申请日：1997-01-24

    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  MEDICAL RESEARCH COUNCIL

    Inventor： PINKEL, Daniel ,  SEGRAVES, Richard ,  ZHAI, Ye ,  ALBERTSON, Donna, G.

    IPC: C12N15 ,  C12Q1 ,  G01N21 ,  G01N33 ,  G01N37 ,  G02B6

    CPC classification number: G01N21/6452 ,  B01J2219/00605 ,  B01J2219/00659 ,  C12Q1/6825 ,  G01N21/7703 ,  G01N2201/0833 ,  G02B6/04

    Abstract: The invention relates to the fabrication and use of biosensors comprising a plurality of optical fibers each fiber having attached to its 'sensor end' biological 'binding partners' (molecules that specifically bind other molecules to form a binding complex such as antibody-antigen, lectin-carbohydrate, nucleic acid-nucleic acid, biotin-avidin, etc.). The biosensor preferably bears two or more different species of biological binding partner. The sensor is fabricated by providing a plurality of groups of optical fibers. Each group is treated as a batch to attach a different species of biological binding partner to the sensor ends of the fibers comprising that bundle. Each fiber, or group of fibers within a bundle, may be uniquely identified so that the fibers, or group of fibers, when later combined in an array of different fibers, can be discretely addressed. Fibers or groups of fibers are then selected and discretely separated from different bundles. The discretely separated fibers are then combined at their sensor ends to produce a high density sensor array of fibers capable of assaying simultaneously the binding of components of a test sample to the various binding partners on the different fibers of the sensor array. The transmission ends of the optical fibers are then discretely addressed to detectors - such as a multiplicity of optical sensors. An optical signal, produced by binding of the binding partner to its substrate to form a binding complex, is conducted through the optical fiber or group of fibers to a detector for each discrete test. By examining the addressed transmission ends of fibers, or groups of fibers, the addressed transmission ends can transmit unique patterns assisting in rapid sample identification by the sensor.

Patent Agency Ranking