公开(公告)号：EP1317852A4

公开(公告)日：2009-07-22

申请号：EP01970583

申请日：2001-08-24

Applicant: AMNIS CORP

Inventor： BASIJI DAVID ,  ORTYN WILLIAM

IPC: G01N21/64 ,  G01N15/00 ,  G01N15/02 ,  G01N15/14 ,  G01N21/27 ,  G06K9/00 ,  H04N5/232

CPC classification number: G06K9/00127 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0232 ,  G01J3/14 ,  G01J3/2823 ,  G01J3/2889 ,  G01N15/14 ,  G01N21/6458 ,  G01N2015/1497

Abstract: Light from an object (152) moving through an imaging system (154) is collected, dispersed, and imaged onto a time delay integration (TDI) detector (148) that is inclined relative to an axis of motion of the object, producing a pixilated output signal. In one embodiment, the movement of the image object over the TDI detector (148) is asynchronous with the movement of the output signal producing an output signal that is a composite of the image of the object at varying focal point along the focal plane. In another embodiment, light from the object is periodically incident on the inclined TDI, producing a plurality of spaced apart images and corresponding output signals that propagate across the TDI detector (148). The inclined plane enables images of FISH probes or other components within an object to be produced at different focal point, so that the 3D spatial relationship between the FISH probes or components can be resolved.

公开(公告)号：EP1955032A1

公开(公告)日：2008-08-13

申请号：EP06838421.3

申请日：2006-11-27

Applicant: University of South Carolina

Inventor： PRIORE, Ryan, J. ,  FREESE, Robert, P. ,  MYRICK, Michael, L. ,  BLACKBURN, John, C.

IPC: G01J3/06

CPC classification number: G01J3/28 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/08 ,  G01N21/274 ,  G01N21/31 ,  G06F17/18 ,  G06F17/50 ,  G06F17/5009 ,  G06F17/5086

Abstract: Methods of selecting spectral elements and system components for a multivariate optical analysis system include providing spectral calibration data for a sample of interest; identifying a plurality of combinations of system components; modeling performance of a pilot system with one of the combinations of system components; determining optimal characteristics of the pilot system; and selecting optimal system components from among the combinations of system components.

公开(公告)号：EP1938741A1

公开(公告)日：2008-07-02

申请号：EP06782982.0

申请日：2006-08-24

Applicant: OLYMPUS MEDICAL SYSTEMS CORP.

Inventor： GONO, Kazuhiro c/o Olympus Medical Systems Corp.

IPC: A61B1/04 ,  A61B1/00 ,  G02B23/24 ,  G02B23/26 ,  H04N7/18

CPC classification number: A61B1/045 ,  A61B1/0005 ,  A61B1/00163 ,  G01J3/02 ,  G01J3/0232 ,  G01J3/2823 ,  G01J3/30 ,  G01J3/51 ,  H04N9/045 ,  H04N2005/2255

Abstract: A living body imaging system which can reduce costs for narrow band imaging more than before is provided. A living body image pickup apparatus according to the present invention includes: a plurality of image pickup units which pick up images of body tissue illuminated by a white light and output the images of the body tissue as image pickup signals; a first spectroscopic unit which passes light in a first wavelength band, spectrally analyzes an image of the body tissue picked up by a first image pickup unit out of the plurality of image pickup units and thereby allows the image of the body tissue to be displayed on a display unit as a first image; and a second spectroscopic unit which passes light in a second wavelength band different from the first wavelength band, spectrally analyzes an image of the body tissue picked up by a second image pickup unit out of the plurality of image pickup units and thereby allows the image of the body tissue to be displayed on the display unit as a second image in which predetermined part of the body tissue is enhanced compared to the first image.

Abstract translation: 提供了一种能够比以前更多地降低窄带成像成本的生物体成像系统。 根据本发明的生物体摄像装置包括：多个图像拾取单元，其拾取由白光照射的身体组织的图像，并输出身体组织的图像作为摄像信号; 第一光谱单元，其使第一波长带中的光通过，对由多个摄像单元中的第一图像拾取单元拾取的身体组织的图像进行光谱分析，从而允许身体组织的图像显示在 作为第一图像的显示单元; 以及第二分光单元，其使不同于第一波长带的第二波长带的光通过光谱分析由多个图像拾取单元中的第二图像拾取单元拾取的身体组织的图像，从而允许 要显示在显示单元上的身体组织作为其中与第一图像相比增强了身体组织的预定部分的第二图像。

公开(公告)号：EP1929278A1

公开(公告)日：2008-06-11

申请号：EP06769715.1

申请日：2006-08-17

Applicant: GLUCOSTATS SYSTEM PTE LTD

Inventor： ZHANG, Xiqin ,  TING, Choon Meng

IPC: G01N21/35 ,  G01N21/00 ,  A61B5/1455 ,  G01N33/49

CPC classification number: G01J3/108 ,  A61B5/14532 ,  A61B5/1455 ,  G01J3/02 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/0235

Abstract: The present invention relates to an arrangement for a selection of a wavelength including a wavelength source for providing a plurality of wavelengths, a wavelength selector for allowing a selection of a desired wavelength from the wavelength source, and a wavelength detector to detect a selected wavelength for subsequent use.

公开(公告)号：EP1169624A4

公开(公告)日：2008-02-20

申请号：EP01905490

申请日：2001-02-15

Applicant: VARIAN AUSTRALIA

Inventor： WILSON PHILIP VALMONT ,  WILLIAMS MARK RICHARD ,  BRICKER DOWER CAMERON ,  HAMMER MICHAEL RON ,  MASTERS MARTIN KEITH ,  CAMPBELL STEWART RALPH ,  LAYTON PETER GEORGE

IPC: G01J3/02 ,  G01J3/18 ,  G01J3/28 ,  G01J3/36 ,  G01J5/62 ,  G01N21/27 ,  G01N21/31

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/1809 ,  G01J3/2803 ,  G01J5/62 ,  G01J2003/1828 ,  G01N21/27 ,  G01N21/31

Abstract: A method and apparatus for the spectrochemical analysis of a sample in which a solid state array detector (82) is used to detect radiation (62) of spectrochemical interest. The invention involves the use of a shutter (72) adjacent the entrance aperture (70) of a polychromator (74-80) to expose the detector (82) to the radiation (62) for varying lengths of time whereby for short duration exposure times charge accumulation in elements (i.e. pixels) of the detector (82) due to high intensity components of the radiation is limited and for longer exposure times charge accumulation in elements (pixels) of the detector (82) due to feeble intesity components of radiation (62) is increased. This ensures that each reading of the detector (82) includes at least one exposure in which the amount of charge accumulated at each wavelength of interest is neither too little or too great. The problems of feeble radiation components not being accurately measurable and of high intensity radiation components exceeding the charge carrying capacity of elements (pixels) of the detector (82) are thereby able to be avoided. An attenuator (90) may be placed between the radiation source (60) and the detector (82) to permit longer exposure times to be used for very high intensity radiation.

公开(公告)号：EP1792166A1

公开(公告)日：2007-06-06

申请号：EP05784455.7

申请日：2005-08-09

Applicant: The General Electric Company

Inventor： LEE, Yuan-Hsiang ,  SUTHERLAND, William, Scott

IPC: G01N21/65 ,  G01J3/44

CPC classification number: G01N21/274 ,  G01J3/0232 ,  G01J3/44 ,  G01N21/65 ,  G01N21/658 ,  G01N2021/656

Abstract: An apparatus (100) for generating a Raman signal of a test sample (130) is disclosed. The apparatus (100) includes a first optical path (260), a second optical path (265), a first station (115), and a second station (125). The first optical path (260) is adapted for coupling with a radiation source (105) that produces a test beam (110) at the first optical path (260). The first station (115) is responsive to the test beam (110) and is adapted to house a test standard (120). The second station (125) is responsive to the test beam (110) and is adapted to house the test sample (130). In response to the test beam (110), Raman radiation from the test standard (120) and the test sample (130) are combined and directed to the second optical path (265), which is adapted for coupling with a spectrometer (140) and a detector (135) for producing a Raman spectrum of the test sample (130).

公开(公告)号：EP1610107B1

公开(公告)日：2007-01-03

申请号：EP05253101.9

申请日：2005-05-19

Applicant: NORTHROP GRUMMAN CORPORATION

Inventor： Zastrow, David M. ,  Kruer, Mark A.

IPC: G01J3/02 ,  G02B26/08 ,  G01J3/08

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0232 ,  G01J5/62 ,  G02B26/0825

公开(公告)号：EP1731892A1

公开(公告)日：2006-12-13

申请号：EP05105036.7

申请日：2005-06-09

Applicant: Agilent Technologies Inc

Inventor： Nebendahl, Bernd

IPC: G01M11/00 ,  G01K11/32

CPC classification number: G01M11/3172 ,  G01J3/0232 ,  G01J3/44 ,  G01K11/32 ,  G01M11/3127

Abstract: The present invention relates to detecting different spectral components of a response signal (S2) received from a device under test -DUT- (12) in response to a stimulus signal (S1), with a first splitter (201) receiving the response signal (S2) and wavelength depending splitting from response signal (S2) a first partial signal (S21) and a second partial signal (S22), a second splitter (202) receiving the second partial signal (S22) and wavelength depending splitting there from a third partial signal (S23), an optical detector (104), for receiving the first partial signal (S21) and the third partial signal (S23) and determining a corresponding optical power, and an optical shutter (203) arranged to be moved to either let through to or block from the optical detector (204) one of: the first partial signal (S21) and the third partial signal (S23).

Abstract translation: 本发明涉及响应于一个激励信号（S1）下测试-DUT-（12）检测从设备接收的响应信号（S2）的不同光谱分量，与接收到响应信号的第一分离器（201）（ S2）和波长从响应信号（S2）的第一局部信号（S21）和接收所述第二部分信号（S22）和波长从第三DEPENDING分裂有第二局部信号（S22），第二分离器（202）根据分离 部分信号（S23）到光检测器（104），用于接收所述第一局部信号（S21）和所述第三部分信号（S23）和确定性采矿对应的光功率，并与设置光学快门（203）被移动到无论哪种 让通过向或从所述光检测器（204）的一个块：第一局部信号（S21）和所述第三部分信号（S23）。

公开(公告)号：EP1724566A1

公开(公告)日：2006-11-22

申请号：EP05720493.5

申请日：2005-03-10

Applicant: Joy World Pacific Co. Ltd.

Inventor： HANAMATSU, Kenkoh, Aomori Industrial Res. Cntr. ,  ONO, Hiroyuki, Hachinohe Technical Laboratory ,  ODAGIRI, Hideo, c/o Joy World Pacific Co., Ltd. ,  SAWA, Takahiro, c/o Joy World Pacific Co., Ltd. ,  MIURA, Katsuyuki, c/o Joy World Pacific Co., Ltd.

IPC: G01N21/35 ,  G01N21/27

CPC classification number: G01N21/4738 ,  G01G19/4146 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/108 ,  G01J3/1256 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/359 ,  G01N33/02 ,  G01N2021/151 ,  G01N2201/0618 ,  G01N2201/067 ,  G01N2201/0696 ,  G01N2201/1293

Abstract: The invention makes it possible to measure a calorie by using near-infrared rays, thereby realizing calorie measurement of an object to be quickly and easily performed using a non-destructive method. A device of measuring calorie of an object includes an object holding unit (1) including a table (2) on which an inspection-target object (M) is placed; a light source unit (20) that supplies light in near-infrared regions to irradiate the inspection-target object (M) placed on the turning table (2); a light reception unit (30) that receives light reflected from or transmitted though the object (M); and a control unit (40) that calculates the calorie of the object (M) in accordance with the absorbances of the light received by the light reception unit (30). In the control unit (40), the calorie of object (M) is calculated in accordance with a regression expression and the absorbances of the light received by the light reception unit (30). In this case, the regression expression is preliminarily calculated in the manner that near-infrared rays are irradiated on a calorie known sample object (M), and multiple-regression analyses are performed on second derivative spectra at the absorbances of light reflected from or transmitted though the sample object (M).

Abstract translation: 本发明使得可以通过使用近红外线，由此实现物体的卡路里测定以快速且容易地使用一种非破坏性的方法测量进行卡路里。 测量物体的卡路里的装置包括：对象保持单元（1）包括（2）上的检查对象物体的哪个（M）被放置的表; 的光源单元（20）做了用品的近红外区域的光照射放置在转台（2）的检查对象物体（M）; （30）做了一个光接收单元接收从光反射式或反式mitted虽然对象（M）; 和（40）做了一个控制单元计算雅舞蹈物体（M）与由光接收单元（30）接收到的光的吸光度的卡路里。 在控制单元（40），物体的卡路里（M）的计算在雅舞蹈与回归表达式和由光接收单元（30）接收到的光的吸光度。 在这种情况下，回归表达式的方式预先计算并近红外线照射卡路里已知样品物体（M）上，和多回归分析是在光的吸光度执行在二阶导数光谱从式或反式mitted反射 虽然样品物体（M）。

公开(公告)号：EP1553399A1

公开(公告)日：2005-07-13

申请号：EP04257407.9

申请日：2004-11-30

Applicant: Samsung Electronics Co., Ltd.

Inventor： Hwang, In-duk ,  Han, Wan-taek ,  Jeon, Kye-jin ,  Park, Kun-kook, Samsung Advanced Inst. of Techn. ,  Choe, Eun-young ,  Hwang, Hyun-tai, Samsung Advanced Inst. of Techn.

IPC: G01N21/35 ,  A61B5/00 ,  G01N33/48

CPC classification number: G01N21/359 ,  A61B5/14532 ,  A61B5/1455 ,  G01J3/0232 ,  G01J3/18

Abstract: There are provided body component measuring apparatus and method using a scanning spectroscopic system. The body component measuring apparatus includes: a light source emitting light; a diffraction grating being movable to disperse the light emitted from the light source into light components having a plurality of wavelength bands; a shutter controlling transmission of the light components having the plurality of wavelength bands; a lens focusing the light components passing through the shutter on the specific portion according to opening or closing of the shutter; and a detector detecting the light components passing through the specific portion. Therefore, by applying different amplifier gains to two specific wavelength bands, it is possible to enhance accuracy of measuring a body component concentration.

Abstract translation: 设置有主体部件使用扫描光谱系统的体成分测定装置包括测量装置和方法：一个发射光的光源;. 衍射光栅是可移动的，以分散来自光源为具有波长带的多个光分量所发射的光; 快门控制具有波长带的多个光分量的传输; 一个透镜聚焦穿过所述特定部分中的快门的光分量gemäß到开口或快门关闭; 和检测器，检测通过所述特定部分的光分量。 因此，通过施加不同的放大器增益，以两个特定波长带，所以能够提高测量身体成分浓度的精确度。