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公开(公告)号：EP2888351A2
公开(公告)日：2015-07-01
申请号：EP13831449.7
申请日：2013-08-13
发明人： NAESBY, Michael , FOLLY, Christophe , NIELSEN, Curt Aimé Friis , HATSCH, Anaelle , SCHWAB, Markus , ZELDER, Oskar , HAEFNER, Stefan , SCHRÖDER, Hartwig , HOFF, Birgit , MOLT, Andrea , DITRICH, Klaus , BREUER, Michael , HARTMANN, Holger , KÖRBER, Karsten
IPC分类号： C12N1/21 , C12N1/15 , C12N1/16 , C12N15/80 , C12N15/81 , C12N15/31 , C12N15/52 , C12P1/00 , C12P17/10 , C07K14/195 , C07K14/37 , A61K31/48 , C07K16/00
CPC分类号： C12P17/12 , C07D209/90 , C07D487/06 , C07K16/40 , C12N9/0004 , C12N9/001 , C12N9/1007 , C12N9/1085 , C12N9/90 , C12N15/52 , C12P17/10 , C12P17/182 , C12Y205/01
摘要： Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.
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公开(公告)号：EP3802813A1
公开(公告)日：2021-04-14
申请号：EP19728375.7
申请日：2019-05-29
申请人： BASF SE
发明人： URBINA, Hugo , QURESHI, Asfia , HUSTON DAVENPORT, Adrienne , TAN, Xuqiu , KUTSCHER, Jochen , FUNKE, Andreas , SEITTER, Michael , HAEFNER, Stefan , LE, Anh-Huy
IPC分类号： C12N9/26
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公开(公告)号：EP3102675B1
公开(公告)日：2019-03-27
申请号：EP15709418.6
申请日：2015-02-02
申请人： BASF SE
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4.发明公开IMPROVED MICROORGANISMS FOR SUCCINIC ACID PRODUCTION 审中-公开VERBESSERTE MIKROORGANISMENFÜRDIE PRODUKTION VONBERNSTEINSÄURE
公开(公告)号：EP3102675A1
公开(公告)日：2016-12-14
申请号：EP15709418.6
申请日：2015-02-02
申请人： BASF SE
发明人： KRAWCZYK, Joanna Martyna , HAEFNER, Stefan , SCHRÖDER, Hartwig , DANTAS COSTA, Esther , ZELDER, Oskar , VON ABENDROTH, Gregory , WITTMANN, Christoph , STELLMACHER, René , BECKER, Judith , LANGE, Anna , LYONS, Benjamin J. , LYONS, Thomas J. , DE CRECY, Eudes , HUGHES, Ewa
CPC分类号： C12N9/1205 , C12N15/52 , C12P7/46 , C12Y207/0104
摘要： The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the pykA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.
摘要翻译： 本发明涉及与其野生型相比具有由pykA基因编码的酶的活性降低的修饰微生物。 本发明还涉及有机化合物的制造方法和改性微生物的使用。
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公开(公告)号：EP2699674B1
公开(公告)日：2016-01-06
申请号：EP12773585.0
申请日：2012-04-18
申请人： BASF SE
CPC分类号： C12N9/16 , A23K20/189 , C07K2319/21
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公开(公告)号：EP2699675B1
公开(公告)日：2015-08-19
申请号：EP12773864.9
申请日：2012-04-18
申请人： BASF SE
CPC分类号： C12N9/16 , C07K2319/21
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公开(公告)号：EP2699675A1
公开(公告)日：2014-02-26
申请号：EP12773864.9
申请日：2012-04-18
申请人： BASF SE
CPC分类号： C12N9/16 , C07K2319/21
摘要： The invention relates to a synthetic phytase with elevated thermostability, elevated stability to acids at pH 2, elevated stability to pepsin and with a broadened active pH range, and to an iso- lated nucleic acid sequence coding for a synthetic phytase and to the use of the phytase in an animal feed for reducing the phosphate content in the slurry and to animal feed additives and animal feeds comprising the synthetic phytase.
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9.发明公开PRODUCTION PROCESS FOR FINE CHEMICALS USING MICROORGANISMS WITH REDUCED ISOCITRATE DEHYDROGENASE ACTIVITY 审中-公开生产中使用微生物具有降低的异柠檬酸脱氢酶活性精细化工
公开(公告)号：EP2283142A1
公开(公告)日：2011-02-16
申请号：EP09738158.6
申请日：2009-04-28
申请人： BASF SE
发明人： HEROLD, Andrea , SCHRÖDER, Hartwig , JEONG, Weol Kyu , KLOPPROGGE, Corinna , ZELDER, Oskar , HAEFNER, Stefan , RICHTER, Ulrike , BECKER, Judith , WITTMANN, Christoph
CPC分类号： C12P13/001 , C12N9/0006 , C12P13/02 , C12P13/08 , C12P13/12 , C12P13/20
摘要： The present invention is directed to a method utilizing a microorganism with reduced isocitrate dehydrogenase activity for the production of fine chemicals. Said fine chemicals may be amino acids, monomers for polymer synthesis, sugars, lipids, oils, fatty acids or vitamins and are preferably amino acids of the aspartate family, especially methionine or lysine, or derivatives of said amino acids, especially cadaverine. Furthermore, the present invention relates to a recombinant microorganism having a reduced isocitrate dehydrogenase activity in comparison to the initial microorganism and the use of such microorganisms in producing fine chemicals such as aspartate family amino acids and their derivatives.
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公开(公告)号：EP1907559A1
公开(公告)日：2008-04-09
申请号：EP06800212.0
申请日：2006-07-18
申请人： BASF SE
发明人： ZELDER, Oskar , HAEFNER, Stefan , KLOPPROGGE, Corinna , SCHRODER, Hartwig , HEROLD, Andrea , PATTERSON, Thomas, A. , HERMANN, Theron , YOCUM, Rogers, R. , WILLIAMS, Mark, K. , PERO, Janice, G.
IPC分类号： C12P13/12
摘要： This invention relates to methionine producing recombinant microorganisms. Specifically, this invention relates to recombinant strains of Corynebacterium that produce increased levels of methionine compared to their wild-type counterparts and further to methods of generating such microorganisms.
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