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公开(公告)号：EP2888351A2
公开(公告)日：2015-07-01
申请号：EP13831449.7
申请日：2013-08-13
发明人： NAESBY, Michael , FOLLY, Christophe , NIELSEN, Curt Aimé Friis , HATSCH, Anaelle , SCHWAB, Markus , ZELDER, Oskar , HAEFNER, Stefan , SCHRÖDER, Hartwig , HOFF, Birgit , MOLT, Andrea , DITRICH, Klaus , BREUER, Michael , HARTMANN, Holger , KÖRBER, Karsten
IPC分类号： C12N1/21 , C12N1/15 , C12N1/16 , C12N15/80 , C12N15/81 , C12N15/31 , C12N15/52 , C12P1/00 , C12P17/10 , C07K14/195 , C07K14/37 , A61K31/48 , C07K16/00
CPC分类号： C12P17/12 , C07D209/90 , C07D487/06 , C07K16/40 , C12N9/0004 , C12N9/001 , C12N9/1007 , C12N9/1085 , C12N9/90 , C12N15/52 , C12P17/10 , C12P17/182 , C12Y205/01
摘要： Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.
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公开(公告)号：EP4281574A1
公开(公告)日：2023-11-29
申请号：EP22703461.8
申请日：2022-01-20
申请人： AJINOMOTO CO., INC. , Evolva SA
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公开(公告)号：EP3341476A1
公开(公告)日：2018-07-04
申请号：EP16763598.6
申请日：2016-08-24
申请人： Ajinomoto Co., Inc. , Evolva SA
发明人： SCHWAB, Markus , BABAU, Maud , FISCHER, David , HATSCH, Anaelle , TAVARES, Sabina de Andrade Pereira , NIELSEN, Curt Aime Friis , KLEIN, Jens , WIRDNAM, Corina Daniela
CPC分类号： C12P13/001 , C07C215/10 , C07F9/09 , C12N1/16 , C12N9/12 , C12N9/1205 , C12P1/02 , C12P7/6481 , C12Y207/01091 , C12Y207/11001
摘要： A method for producing an objective substance such as phytosphingosine and sphinganine using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance and modified so that the expression and/or activities of proteins encoded by LCB4 and CKA2 genes are reduced in a culture medium, and collecting the objective substance from cells of the yeast and/or the culture medium.
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公开(公告)号：EP4281575A1
公开(公告)日：2023-11-29
申请号：EP22703462.6
申请日：2022-01-20
申请人： AJINOMOTO CO., INC. , Evolva SA
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公开(公告)号：EP3341476B1
公开(公告)日：2019-08-07
申请号：EP16763598.6
申请日：2016-08-24
申请人： Ajinomoto Co., Inc. , Evolva SA
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公开(公告)号：EP3341488A1
公开(公告)日：2018-07-04
申请号：EP16763597.8
申请日：2016-08-24
申请人： Ajinomoto Co., Inc. , Evolva SA
发明人： SCHWAB, Markus , WIRDNAM, Corina Daniela , TANGE, Thomas Oestergaard , BABAU, Maud , HATSCH, Anaelle , DELEGRANGE, Fanny , FISCHER, David , TAVARES, Sabina de Andrade Pereira
IPC分类号： C12P13/02
CPC分类号： C12P13/02 , C12N2500/05 , C12N2500/30 , C12P13/001 , C12Y101/01102 , C12Y114/13169 , C12Y114/18 , C12Y203/01 , C12Y203/01024 , C12Y203/0105 , C12Y203/01199 , C12Y204/0108 , C12Y207/01091 , C12Y207/11001 , C12Y305/01023 , C12Y403/01017
摘要： A method for producing an objective substance such as sphingoid bases and sphingolipids using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture medium containing an additive that is able to associate with, bind to, solubilize, and/or capture the objective substance, and collecting the objective substance from cells of the yeast and/or the culture medium.
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