公开(公告)号：US20070258897A1

公开(公告)日：2007-11-08

申请号：US11630444

申请日：2005-06-23

Applicant: Andrew Devitt ,  Christopher Gregory

Inventor： Andrew Devitt ,  Christopher Gregory

IPC: A61K39/395 ,  A61K48/00 ,  A61P43/00 ,  G01N33/53 ,  G01N33/567 ,  G01N33/574

CPC classification number: C07K16/30 ,  A61K2039/505 ,  C07K16/1203 ,  C07K2317/82

Abstract: The present invention provides a method of enhancing an immune response to apoptotic cells, the method comprising administration of a specific binding member which specifically binds to a microbial antigen. Also provided are pharmaceutical compositions comprising such antibodies and assays to identify specific binding members capable of enhancing an immune response to apoptotic cells. Also described are methods for the treatment of cancer using antibodies which bind to an apoptotic cell intracellular antigen.

Abstract translation: 本发明提供增强对凋亡细胞的免疫应答的方法，所述方法包括施用特异性结合微生物抗原的特异性结合成员。 还提供了包含这种抗体和测定以鉴定能够增强对凋亡细胞的免疫应答的特异性结合成员的药物组合物。 还描述了使用结合凋亡细胞细胞内抗原的抗体治疗癌症的方法。

公开(公告)号：US20070031600A1

公开(公告)日：2007-02-08

申请号：US11497531

申请日：2006-08-02

Applicant: Andrew Devitt

Inventor： Andrew Devitt

IPC: C23C16/00

CPC classification number: C23C16/458 ,  B05C13/00 ,  C03B35/147 ,  C03C15/00 ,  C03C17/002 ,  C03C23/0075 ,  C23C14/562 ,  C23C16/4409 ,  C23C16/50 ,  C23C16/545 ,  F16C32/0614 ,  F16C33/748 ,  F16C2300/62 ,  H01J37/3277 ,  H01J37/32834 ,  H01L21/67028 ,  H01L21/67034 ,  H01L21/67051 ,  H01L21/67739 ,  Y02P40/57

Abstract: A method and apparatus for coating and baking and deposition of surfaces on glass substrate or flexible substrate, such as films and thin glass sheets or other similar work pieces as it transitions thru and between small gaps of aero-static or hydro-static porous media bearings and differentially pumped vacuum grooves, in a non-contact manner, in order to process within a vacuum environment. The process is also intended to incorporate simultaneous and immediately sequential ordering of various processes.

Abstract translation: 一种用于在玻璃基板或柔性基板上涂覆和烘烤和沉积表面的方法和装置，例如薄膜和薄玻璃板或其它类似的工件，当它们穿过静电或静电多孔介质轴承的小间隙 以及差分抽真空槽，以非接触的方式，以在真空环境中进行处理。 该过程还旨在并入并且立即顺序排列各种过程。

公开(公告)号：US20070034228A1

公开(公告)日：2007-02-15

申请号：US11497526

申请日：2006-08-02

Applicant: Andrew Devitt

Inventor： Andrew Devitt

IPC: B08B3/12 ,  B08B3/00 ,  B05D3/12

CPC classification number: C23C16/458 ,  B05C13/00 ,  C03B35/147 ,  C03C15/00 ,  C03C17/002 ,  C03C23/0075 ,  C23C14/562 ,  C23C16/4409 ,  C23C16/50 ,  C23C16/545 ,  F16C32/0614 ,  F16C33/748 ,  F16C2300/62 ,  H01J37/3277 ,  H01J37/32834 ,  H01L21/67028 ,  H01L21/67034 ,  H01L21/67051 ,  H01L21/67739 ,  Y02P40/57

Abstract: A method and apparatus for cleaning, drying, coating, baking etching and deposition of surfaces on glass substrate as it transitions thru and between small gaps between hydro-static porous media bearings. Due to the non-contact nature of the device extremely high pressures can be induced upon the work piece through various fluids without damage to the substrate, allowing the system to utilize the viscous nature of fluids to accomplish the desired cleaning, drying, coating, etching or baking. The process also allows for simultaneous and immediately sequential ordering of processes.

Abstract translation: 一种用于清洗，干燥，涂覆，烘烤蚀刻和沉积玻璃基板上的表面的方法和装置，因为其在水力静力多孔介质轴承之间经过并且在小间隙之间转变。 由于设备的非接触性质，可以通过各种流体在工件上引起非常高的压力而不损坏基板，从而允许系统利用流体的粘性来实现所需的清洁，干燥，涂覆，蚀刻 或烘焙。 该过程还允许同时且立即顺序排序过程。

公开(公告)号：US20060060259A1

公开(公告)日：2006-03-23

申请号：US11206296

申请日：2005-08-18

Applicant: Andrew Devitt

Inventor： Andrew Devitt

IPC: B25B11/00 ,  B65B31/04 ,  B05D3/00 ,  A47J41/00

CPC classification number: H01L21/67784 ,  B05D3/0493 ,  B25B11/005 ,  F16C29/025 ,  F16C32/0618 ,  F16C33/748 ,  F16C2300/62 ,  F16J15/40 ,  F16J15/443 ,  G03F7/70716 ,  G03F7/70816 ,  G03F7/70841 ,  H01J37/20 ,  H01J2237/166 ,  H01J2237/2006 ,  H01J2237/202 ,  H01J2237/28 ,  H01J2237/31701 ,  H01J2237/3175 ,  H01L21/67126 ,  H01L21/68 ,  H01L21/68714

Abstract: A stage for processing a substrate, especially useful for vacuum applications, has a recess just large enough to hold a substantially flat substrate and a chuck or holder but not much more. The perimeter of the recessed side has an air bearing surface separated from the recess by differentially pumped groves and seal lands. The air bearing lands are urged against a reference plate guide surface and the seal lands being substantially coplanar create a resistance to flow between the groves and recess, on the other side of the base reference plate mounts the radiation source. The VCS may operate in a vacuum environment itself, or in another preferred embodiment, it provides the possibility for multiple stages moving between process or inspection steps within the same tool or process sequence.

Abstract translation: 用于处理衬底的阶段，特别适用于真空应用，具有刚好足够大以容纳基本上平坦的衬底和卡盘或保持器而不是更多的凹部。 凹入侧的周边具有空隙部分，该空气轴承表面通过差分泵送的格栅和密封接头与凹部分离。 空气轴承平台被推靠在参考板引导表面上，并且密封平台基本上共面地在基部参考板的另一侧上安装辐射源而产生在凹槽和凹槽之间的流动阻力。 VCS可以在真空环境中操作，或者在另一个优选实施例中，其提供在相同工具或处理顺序内的过程或检查步骤之间的多个阶段移动的可能性。

公开(公告)号：US20130195940A1

公开(公告)日：2013-08-01

申请号：US13877956

申请日：2011-10-05

Applicant: Andrew Devitt

Inventor： Andrew Devitt

IPC: C07K16/28 ,  A61K38/17 ,  G01N33/50

CPC classification number: C07K16/2821 ,  A61K38/1774 ,  C07K2317/76 ,  G01N33/5047

Abstract: The present disclosure relates generally to methods and materials for modulating the recruitment of macrophages or monocytes to sites at which they may contribute to disease initiation or progression. Embodiments of the disclosure comprise providing a modulator of the activity of ICAM-3 or proximal to the site.

Abstract translation: 本公开一般涉及用于调节巨噬细胞或单核细胞募集到其可能有助于疾病发生或进展的部位的方法和材料。 本公开的实施方案包括提供ICAM-3的活性或位于该位点附近的调节剂。

公开(公告)号：US20080305043A1

公开(公告)日：2008-12-11

申请号：US11667973

申请日：2005-11-16

Applicant: Christopher D. Gregory ,  Andrew Devitt ,  Ian Tennant

Inventor： Christopher D. Gregory ,  Andrew Devitt ,  Ian Tennant

IPC: A61K49/00 ,  G01N33/53

CPC classification number: G01N33/56966 ,  G01N1/30 ,  G01N33/92 ,  G01N2400/50 ,  G01N2510/00

Abstract: Described is a method of detecting non-viable cells in a sample of cells, the method comprising contacting a sample of the cells with a detectable reagent and detecting binding of said reagent to cells of said sample. The detectable reagent is milk, a milk product or component thereof. A component which may be used is a lipopolysaccharide-binding protein, for example lactoferrin. The method may be performed in low Ca2+ or Ca2+-free conditions.

Abstract translation: 描述了一种检测细胞样品中的非活细胞的方法，所述方法包括使细胞样品与可检测试剂接触并检测所述试剂与所述样品细胞的结合。 可检测试剂是牛奶，奶制品或其成分。 可以使用的组分是脂多糖结合蛋白，例如乳铁蛋白。 该方法可以在低Ca2 +或无Ca2 +的条件下进行。

公开(公告)号：US20060219605A1

公开(公告)日：2006-10-05

申请号：US11274513

申请日：2005-11-08

Applicant: Andrew Devitt

Inventor： Andrew Devitt

IPC: B07B9/00

CPC classification number: C03B23/008 ,  B65G49/065 ,  B65G51/03 ,  B65G2249/02 ,  B65G2249/04 ,  C03B23/0235 ,  F16C29/025 ,  F16C32/0618 ,  H01L21/67784

Abstract: Thin substrates, such as flat glass panels, are levitated on a porous media air bearing creating a pressurized film of air and preloaded against the air film by negative pressure areas. The pressure can be distributed most uniformly across the pressure areas by defusing the pressure through a porous medium. Such a bearing can be used for glass flattening by holding the glass such that the unevenness is migrated to the side opposite the side to be worked on.

Abstract translation: 诸如平板玻璃面板的薄基底在多孔介质空气轴承上悬浮，产生加压的空气膜，并通过负压区域预压在空气膜上。 压力通过多孔介质排除压力可以最均匀地分布在压力区域上。 这样的轴承可以通过保持玻璃而使玻璃变平，使得凹凸迁移到与被加工面相反的一侧。