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1.发明申请公开(公告)号：US20150105764A1
公开(公告)日：2015-04-16
申请号：US14572042
申请日：2014-12-16
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： RAED N. RIZQ , ROGER N. HASTINGS , DAVID J. SOGARD
IPC: A61B18/02
CPC classification number: A61B18/02 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
Abstract: A cryotherapy balloon catheter includes a compliant cryotherapy balloon comprising a distal balloon section dimensioned for placement within a renal artery and a proximal balloon section dimensioned to abut against an ostium of the renal artery and extend into at least a portion of the abdominal aorta. The compliant balloon has a diameter that varies non-uniformly along a length of the compliant balloon, such that a diameter at the proximal balloon section is larger than a diameter of the distal balloon section. The cryotherapy balloon catheter may be configured to deliver cryogenic therapy to at least the ostium of the renal artery sufficient to irreversibly terminate renal sympathetic nerve activity, such as by causing neurotmesis of renal nerve fibers and ganglia at the ostium of the renal artery.
Abstract translation: 冷冻治疗气囊导管包括顺应性冷冻治疗气囊，其包括尺寸适于放置在肾动脉内的远端球囊部分和近端球囊部分，其近似球囊部分的尺寸设置成抵靠肾动脉的口并且延伸到腹主动脉的至少一部分。 顺应性球囊具有沿着柔顺气囊的长度不均匀地变化的直径，使得近端球囊部分处的直径大于远端球囊部分的直径。 冷冻治疗气球导管可以被配置为将低温治疗递送至至少肾动脉的口，足以不可逆地终止肾交感神经活动，例如通过在肾动脉的口处引起肾神经纤维和神经节的神经痛。
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2.发明申请RENAL DENERVATION AND STIMULATION EMPLOYING WIRELESS VASCULAR ENERGY TRANSFER ARRANGEMENT 有权使用无线血管能量转移安排的肾衰竭和刺激公开(公告)号：US20130274735A1
公开(公告)日：2013-10-17
申请号：US13926935
申请日：2013-06-25
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： ROGER N. HASTINGS , ANTHONY C. VRBA , CLARA DAVIS
CPC classification number: A61B18/1206 , A61B5/04001 , A61B5/0538 , A61B18/1492 , A61B2018/00023 , A61B2018/00047 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2018/00875 , A61B2018/167 , A61B2090/3966 , A61F2/82 , A61F2250/0001 , A61N1/36125
Abstract: Devices, systems, and methods provide for intravascular or extravascular delivery of renal denervation therapy and/or renal control stimulation therapy. Wireless vascular thermal transfer apparatuses and methods provide for one or both of production of current densities sufficient to ablate renal nerves and terminate renal sympathetic nerve activity, and production of current densities sufficient to induce endothelium dependent vasodilation of the renal artery bed. A common apparatus may be used for both renal ablation and control of renal function locally after renal denervation.
Abstract translation: 装置，系统和方法提供肾去神经治疗和/或肾脏控制刺激疗法的血管内或血管外递送。 无线血管热转移装置和方法提供足以消融肾神经和终止肾交感神经活动的电流密度的产生中的一种或两种，以及足以诱导肾动脉床的内皮依赖性血管舒张的电流密度的产生。 在肾去神经支配之后，常见的装置可用于肾消融和局部肾功能的控制。
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3.发明申请公开(公告)号：US20130123625A1
公开(公告)日：2013-05-16
申请号：US13676871
申请日：2012-11-14
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： ROGER N. HASTINGS , MICHAEL J. PIKUS , KEVIN D. EDMUNDS , SCOTT R. SMITH , LEONARD B. RICHARDSON , TAT-JIN TEO
CPC classification number: A61N7/00 , A61B8/12 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00636 , A61B2090/3784 , A61N7/022 , A61N2007/003 , A61N2007/0052 , A61N2007/0078 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
Abstract: Intravascular nerve modulation systems and methods for making and using the same are disclosed. An example system may include an elongate shaft having a proximal end region and a distal end region and a central longitudinal axis. An ablation transducer may be disposed at the distal end region. The system may also include a rotational drive configured to rotate the ablation transducer about the central longitudinal axis. A control and power system may be operably connected to the ablation transducer and the rotational drive. In some instances, the ablation transducer may be a combined ablation and imaging transducer.
Abstract translation: 公开了血管内神经调节系统及其制造和使用方法。 示例性系统可以包括具有近端区域和远端区域以及中心纵向轴线的细长轴。 消融换能器可以设置在远端区域。 该系统还可以包括旋转驱动器，其构造成围绕中心纵向轴线旋转消融换能器。 控制和动力系统可以可操作地连接到消融换能器和旋转驱动器。 在一些情况下，消融换能器可以是组合消融和成像换能器。
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公开(公告)号：US20170224983A1
公开(公告)日：2017-08-10
申请号：US15495612
申请日：2017-04-24
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： GRAIG L. KVEEN , DOUGLAS R. SAHOLT , ROGER N. HASTINGS , RICHARD C. GUNDERSON
CPC classification number: A61N1/0573 , A61M25/0082 , A61M2025/0095 , A61N1/362 , A61N1/37205 , A61N1/37288 , A61N1/3756
Abstract: Some embodiments of an electrical stimulation system employ wireless electrode assemblies to provide pacing therapy, defibrillation therapy, or other stimulation therapy. In certain embodiments, the wireless electrode assemblies may include a guide wire channel so that each electrode assembly can be advanced over a guide wire instrument through the endocardium. For example, a distal tip portion of a guide wire instrument can penetrate through the endocardium and into the myocardial wall of a heart chamber, and the electrode assembly may then be advanced over the guide wire and into the heart chamber wall. In such circumstances, the guide wire instrument (and other portions of the delivery system) can be retracted from the heart chamber wall, thereby leaving the electrode assembly embedded in the heart tissue.
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公开(公告)号：US20170120079A1
公开(公告)日：2017-05-04
申请号：US15403970
申请日：2017-01-11
Applicant: Boston Scientific Scimed, Inc.
Inventor： TORSTEN SCHEUERMANN , TAT-JIN TEO , ROGER N. HASTINGS
CPC classification number: A61N7/02 , A61B5/0071 , A61B5/0095 , A61B5/01 , A61B5/04001 , A61B5/201 , A61B5/4029 , A61B8/4461 , A61B18/02 , A61B18/1492 , A61B18/24 , A61B18/26 , A61B2018/00023 , A61B2018/00214 , A61B2018/0022 , A61B2018/00285 , A61B2018/00386 , A61B2018/00404 , A61B2018/00494 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2090/3966 , A61N1/403 , A61N7/00 , A61N2007/003 , A61N2007/0082 , A61N2007/0091
Abstract: Apparatuses for identifying nerve tissue and methods for making and using the same are disclosed. An example apparatus may include an elongate shaft having a distal region configured to be percutaneously deployed within a patient. An active imaging structure may be disposed on the distal region. The active imaging structure may be configured to remotely image nerve tissue by exciting a signal in nerve tissue from a percutaneous location and receiving the signal from a percutaneous location. The active imaging structure may include one or more probes.
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Patent Agency Ranking
6.发明申请ULTRASOUND RENAL NERVE ABLATION AND IMAGING CATHETER WITH DUAL-FUNCTION TRANSDUCERS 审中-公开带双功能传感器的超声波神经线吸收和成像导管公开(公告)号：US20140276050A1
公开(公告)日：2014-09-18
申请号：US14194371
申请日：2014-02-28
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： MARK L. JENSON , ROGER N. HASTINGS , SCOTT R. SMITH
CPC classification number: A61B8/445 , A61B8/085 , A61B8/12 , A61B8/4483 , A61B8/56 , A61B17/320016 , A61B2090/3784 , A61N7/00 , A61N7/022 , A61N2007/003 , A61N2007/0043 , A61N2007/0052 , A61N2007/0095
Abstract: Systems for nerve and tissue modulation are disclosed. An example system may include an intravascular nerve modulation system including an elongated shaft having a proximal end region and a distal end region. The system may further include one or more dual-function ultrasound transducers for performing imaging and tissue modulation.
Abstract translation: 公开了用于神经和组织调节的系统。 示例性系统可以包括血管内神经调节系统，其包括具有近端区域和远端区域的细长轴。 该系统还可以包括用于执行成像和组织调制的一个或多个双功能超声换能器。
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7.发明申请公开(公告)号：US20140088629A1
公开(公告)日：2014-03-27
申请号：US14032553
申请日：2013-09-20
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： ROGER N. HASTINGS , MARK L. JENSON
IPC: A61B17/32
CPC classification number: A61N7/022 , A61N2007/0026 , A61N2007/003 , A61N2007/0043 , A61N2007/0078
Abstract: Systems for nerve and tissue modulation are disclosed. An example system may include a first elongate element having a distal end and a proximal end and having at least one nerve modulation element disposed adjacent the distal end. The nerve modulation element may be positioned or moveable to target a particular target region. The nerve modulation element may be an ultrasound transducer. The nerve modulation element may be configured to be operated at a low intensity to provide a thermal nerve block or a high intensity to effect tissue modulation.
Abstract translation: 公开了用于神经和组织调节的系统。 示例性系统可以包括具有远端和近端的第一细长元件，并且具有邻近远端设置的至少一个神经调制元件。 神经调制元件可以被定位或可移动以靶向特定的目标区域。 神经调制元件可以是超声换能器。 神经调制元件可以被配置为以低强度操作以提供热神经阻滞或高强度来实现组织调制。
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公开(公告)号：US20170136233A1
公开(公告)日：2017-05-18
申请号：US15380160
申请日：2016-12-15
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： ROGER N. HASTINGS , ANUPAMA SADASIVA , MICHAEL J. PIKUS , GRAIG L. KVEEN
CPC classification number: A61N1/0573 , A61N1/057 , A61N1/0587 , A61N1/059 , A61N1/08 , A61N1/362 , A61N1/37205 , A61N1/37229 , A61N1/375 , A61N1/3756 , A61N1/3787
Abstract: Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Also disclosed are various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
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公开(公告)号：US20160175583A1
公开(公告)日：2016-06-23
申请号：US15058941
申请日：2016-03-02
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： GRAIG L. KVEEN , DOUGLAS R. SAHOLT , ROGER N. HASTINGS , RICHARD C. GUNDERSON
CPC classification number: A61N1/0573 , A61M25/0082 , A61M2025/0095 , A61N1/362 , A61N1/37205 , A61N1/37288 , A61N1/3756
Abstract: Some embodiments of an electrical stimulation system employ wireless electrode assemblies to provide pacing therapy, defibrillation therapy, or other stimulation therapy. In certain embodiments, the wireless electrode assemblies may include a guide wire channel so that each electrode assembly can be advanced over a guide wire instrument through the endocardium. For example, a distal tip portion of a guide wire instrument can penetrate through the endocardium and into the myocardial wall of a heart chamber, and the electrode assembly may then be advanced over the guide wire and into the heart chamber wall. In such circumstances, the guide wire instrument (and other portions of the delivery system) can be retracted from the heart chamber wall, thereby leaving the electrode assembly embedded in the heart tissue.
Abstract translation: 电刺激系统的一些实施例采用无线电极组件来提供起搏治疗，除颤疗法或其它刺激疗法。 在某些实施例中，无线电极组件可以包括引导线通道，使得每个电极组件可以通过心内膜在导丝器械上前进。 例如，导丝器械的远侧末端部分可以穿透心内膜并进入心脏室的心肌壁，然后可以将电极组件推进到导丝上并进入心室壁。 在这种情况下，引导线器械（和输送系统的其它部分）可以从心室壁缩回，从而使电极组件嵌入在心脏组织中。
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公开(公告)号：US20140081301A1
公开(公告)日：2014-03-20
申请号：US14029452
申请日：2013-09-17
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： BINH C. TRAN , ROGER N. HASTINGS , MARK L. JENSON , LEONARD B. RICHARDSON , MICHAEL J. PIKUS
IPC: A61B17/32
CPC classification number: A61N7/022 , A61B2017/0011 , A61B2017/320069 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/3784 , A61N2007/0026 , A61N2007/0078 , A61N2007/0091 , A61N2007/027
Abstract: Systems for nerve and tissue modulation are disclosed. An example system may include a first elongate element having a distal end and a proximal end and having at least one nerve modulation element disposed adjacent the distal end. The nerve modulation element may be positioned or moveable to target a particular tissue region. The nerve modulation element may be an ultrasound transducer.
Abstract translation: 公开了用于神经和组织调节的系统。 示例性系统可以包括具有远端和近端的第一细长元件，并且具有邻近远端设置的至少一个神经调制元件。 神经调制元件可以被定位或可移动以靶向特定的组织区域。 神经调制元件可以是超声换能器。
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