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1.发明申请METHOD AND DEVICE FOR PREPARING AND/OR ANALYZING BIOCHEMICAL REACTION CARRIERS 审中-公开用于制备和/或分析生物化学反应载体的方法和装置公开(公告)号：US20080214412A1
公开(公告)日：2008-09-04
申请号：US11971805
申请日：2008-01-09
IPC分类号： C40B50/14
CPC分类号： G01N21/6454 , B01J19/0046 , B01J19/0093 , B01J2219/00317 , B01J2219/00432 , B01J2219/00436 , B01J2219/00439 , B01J2219/00441 , B01J2219/00448 , B01J2219/00479 , B01J2219/00497 , B01J2219/00511 , B01J2219/00529 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00603 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00702 , B01J2219/00704 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L3/502715 , B01L3/5085 , B01L2300/0654 , B01L2300/069 , B01L2300/0816 , B01L2300/0864 , B82Y30/00 , C12N15/10 , C12P19/34 , C40B40/06 , C40B40/10 , C40B50/14 , G01N21/253 , G01N33/551 , G03F7/70216 , Y10S435/97 , Y10S435/973
摘要： The present invention relates to arrays of biochemical and/or biofunctional elements such as nucleic acids (oligonucleotides, for example) or other biomolecules on a carrier surface and methods of producing such arrays using photoactivation of predetermined areas for synthesis using an illumination matrix that is computer-controlled to generate an exposure pattern. This exposure pattern can be adjusted and monitored by computer using a light sensor matrix, for example a CCD matrix, to allow precise, controlled illumination of specific regions and therefore attachment of array building blocks to those specific regions. The methods and compositions of the invention permit spatially resolved photochemical synthesis of polymer probes on a carrier.
摘要翻译： 本发明涉及生物化学和/或生物功能元件的阵列，例如载体表面上的核酸（例如寡核苷酸）或其它生物分子，以及使用计算机的照明矩阵使用预定区域进行合成的光活化来制备此类阵列的方法 - 控制以产生曝光模式。 可以使用光传感器矩阵（例如CCD矩阵）通过计算机来调整和监视该曝光图案，以允许特定区域的精确控制照明，并因此使阵列构建块附着到那些特定区域。 本发明的方法和组合物允许在载体上空间分辨聚合物探针的光化学合成。
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公开(公告)号：US20080146791A1
公开(公告)日：2008-06-19
申请号：US11946666
申请日：2007-11-28
申请人： Cord F. Stahler , Peer F. Stahler , Manfred Muller
发明人： Cord F. Stahler , Peer F. Stahler , Manfred Muller
IPC分类号： C07H1/08
CPC分类号： B82Y30/00 , B01J2219/00286 , B01J2219/00434 , B01J2219/00436 , B01J2219/00527 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00619 , B01J2219/00626 , B01J2219/0063 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00704 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01J2219/00727 , B01J2219/00729 , C12N15/1006 , C12Q1/6806 , G01N30/02 , C12Q2565/629 , C12Q2565/501 , B01D15/3804
摘要： The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier.
摘要翻译： 本发明涉及使用微流体载体从样品中分离靶分子的提取方法。
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公开(公告)号：US20090170802A1
公开(公告)日：2009-07-02
申请号：US12400493
申请日：2009-03-09
申请人： Peer F. Stahler , Cord F. Stahler , Manfred Muller
发明人： Peer F. Stahler , Cord F. Stahler , Manfred Muller
IPC分类号： A61K31/713 , C12P19/34 , C07H1/00 , C07H21/00
CPC分类号： G06F19/22 , B01J19/0046 , B01J19/0093 , B01J2219/00317 , B01J2219/00432 , B01J2219/00436 , B01J2219/00439 , B01J2219/00441 , B01J2219/00448 , B01J2219/00479 , B01J2219/00497 , B01J2219/00511 , B01J2219/00529 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00603 , B01J2219/00605 , B01J2219/00608 , B01J2219/00621 , B01J2219/00626 , B01J2219/00648 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00702 , B01J2219/00704 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L3/502707 , B01L3/5085 , B01L2300/0654 , B01L2300/069 , B01L2300/0864 , B82Y30/00 , C12N15/10 , C12N15/66 , C12P19/34 , C40B40/06 , C40B40/10 , C40B50/14 , G03F7/70216 , G06F19/28
摘要： The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) provision of a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesis of nucleic acid fragments having in each case different base sequences in several of the individual reaction areas, and (c) detachment of the nucleic acid fragments from individual reaction areas.
摘要翻译： 本发明涉及用于制备聚合物的方法，特别是任选序列的合成核酸双链，包括以下步骤：（a）提供具有包含多个单独反应区域的表面积的载体，（b） 在几种单独的反应区域中解析各种情况下具有不同碱基序列的核酸片段的合成，和（c）从各个反应区域脱离核酸片段。
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