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公开(公告)号：US20150150614A1
公开(公告)日：2015-06-04
申请号：US14554521
申请日：2014-11-26
发明人： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
CPC分类号： A61B17/8625 , A61B17/864 , A61B17/866 , A61L31/146 , A61L2430/02 , B33Y80/00
摘要： A bionic apparatus is provided. The bionic apparatus includes a flexible portion having a plurality of pores, a rigid portion connected with the flexible portion, and a supporting element disposed in the flexible portion. The pore size of each pore is between 50 μm to 500 μm. The flexible portion, the rigid portion and the supporting element are one-piece formed by a additive manufacturing process.
摘要翻译： 提供仿生设备。 仿生装置包括具有多个孔的柔性部分，与柔性部分连接的刚性部分和设置在柔性部分中的支撑元件。 各孔的孔径为50μm〜500μm。 柔性部分，刚性部分和支撑元件是通过添加剂制造工艺形成的一体的。
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公开(公告)号：US20210137698A1
公开(公告)日：2021-05-13
申请号：US16730000
申请日：2019-12-30
发明人： Fang-Jie JANG , Pei-I TSAI , De-Yau LIN , An-Li CHEN , Fon-Yih TSUANG , Chih-Chieh HUANG , Hsin-Hsin SHEN
IPC分类号： A61F2/44
摘要： The disclosure relates to a vertebral body implant including a flexible main body and at least one pedicle screw joint. The flexible main body is an integrally formed single piece having at least one joint-accommodating hole and at least one opening connected to the at least one joint-accommodating hole. The pedicle screw joint is an integrally formed single piece movably accommodated in the at least one joint-accommodating hole.
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公开(公告)号：US20150150557A1
公开(公告)日：2015-06-04
申请号：US14555251
申请日：2014-11-26
发明人： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
IPC分类号： A61B17/08
CPC分类号： A61B17/686 , A61F2/0811 , A61F2002/0835 , A61F2002/0864
摘要： A bionic fixing apparatus is provided. The bionic fixing apparatus includes a body having a through hole and at least one slit. The through hole penetrates the body from the top surface to the bottom surface to form a top opening and a bottom opening. An inner diameter of the top opening is larger than an inner diameter of the bottom opening. The slit is connected to the bottom opening and extends upwardly from the bottom surface of the body, such that the body has a flexible bottom portion.
摘要翻译： 提供仿生定影装置。 仿生定影装置包括具有通孔和至少一个狭缝的主体。 通孔从上表面穿透到底面，形成顶部开口和底部开口。 顶部开口的内径大于底部开口的内径。 狭缝连接到底部开口并从主体的底部表面向上延伸，使得主体具有柔性底部。
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公开(公告)号：US20150147722A1
公开(公告)日：2015-05-28
申请号：US14555204
申请日：2014-11-26
发明人： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
CPC分类号： A61B17/8625 , A61B17/72 , A61C8/0018 , A61C8/0022 , A61C8/0037 , A61C2008/0046 , A61F2/442
摘要： A bionic fixing apparatus is provided. The bionic fixing apparatus includes a flexible portion having at least one trench. The trench is disposed on the surface of the flexible portion and has a first end and a second end. An interval is disposed between the first end and the second end. The trench is disposed for spreading the stress applied on the bionic fixing apparatus and preventing stress concentration and stress shielding.
摘要翻译： 提供仿生定影装置。 仿生定影装置包括具有至少一个沟槽的柔性部分。 沟槽设置在柔性部分的表面上并具有第一端和第二端。 间隔设置在第一端和第二端之间。 沟槽设置用于扩展施加在仿生定影装置上的应力，并且防止应力集中和应力屏蔽。
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公开(公告)号：US20230172720A1
公开(公告)日：2023-06-08
申请号：US17550889
申请日：2021-12-14
发明人： Fang-Chieh CHANG , Pei-I TSAI , Shih-Ping LIN , Ming-Jun LI , Chih-Chieh HUANG , Hsin-Hsin SHEN , Meng-Huang WU
CPC分类号： A61F2/4425 , A61F2/30771 , A61F2002/443 , A61F2002/30599 , A61F2002/30326 , A61F2002/30784 , A61F2002/30354
摘要： An artificial intervertebral disc is configured to be inserted between adjacent human vertebrae. The artificial intervertebral disc includes a first connection block, a joint block and a second connection block. The joint block has a convex surface and a rear surface. The rear surface of the joint block is stacked on the first connection block. The second connection block is slidably stacked on the convex surface of the joint block, such that the second connection block is movable relative to the first connection block. In addition, the convex surface is a curved surface, and the convex surface is arranged off-axis with respect to the rear surface.
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公开(公告)号：US20210338414A1
公开(公告)日：2021-11-04
申请号：US17243858
申请日：2021-04-29
发明人： Chih-Chieh HUANG , Jeng-Liang KUO , Hui-Ting HUANG , Shiun-Yin CHANG , Meng-Hsueh LIN , Cheng-Yi WU , Lih-Tao HSU , Pei-I TSAI , Hsin-Hsin SHEN , Chih-Yu CHEN , Kuo-Yi YANG , Chun-Hsien MA
IPC分类号： A61F2/08
摘要： A tissue repair device and a method for using the same are provided. The tissue repair device includes a body portion and at least one wire. The body portion includes an inner layer and an outer layer. The inner layer is close to a tissue, wherein the inner layer includes a hydrophilic structure, and the outer layer includes a hydrophobic structure. The wire is connected to the body portion to fix the body portion to the tissue.
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公开(公告)号：US20220175432A1
公开(公告)日：2022-06-09
申请号：US17112573
申请日：2020-12-04
发明人： Hsin-Hsin SHEN , Pei-I TSAI , Kuo-Yi YANG , Fang-Jie JANG , An-Li CHEN , Shih-Ping LIN , Chih-Chieh HUANG , Yi-Hung WEN , Wei-Lun FAN , Shin-I HUANG
IPC分类号： A61B17/86
摘要： A bone screw includes an external screw thread, an internal supporter structure and a porous layer. The internal supporter structure is inside the external screw thread. The internal supporter structure includes a screw thread supporter or a polygonal wall supporter. The porous layer is on a surface of the internal supporter structure. Therefore, the bone screw has an increased strength and also provides postoperative healing effect.
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8.发明申请BIOCHEMISTRY REACTIVE MATERIAL AND DEVICE FOR ELIMINATING ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN (LDL) AND METHOD FOR TREATING BLOOD OR PLASMA EX VIVO TO ELIMINATE ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN THEREIN 审中-公开用于消除电子低密度脂蛋白（LDL）的生物化学反应性材料和装置以及用于治疗血液或血浆的方法以消除电子密度低密度脂蛋白公开(公告)号：US20170044516A1
公开(公告)日：2017-02-16
申请号：US14984938
申请日：2015-12-30
发明人： Pei-Yi Tsai , Chih-Hung CHEN , Yi-Hung LIN , Chih-Chieh HUANG , Hsin-Hsin SHEN , Liang-Yin KE , Chu-Huang CHEN
CPC分类号： C12N11/12 , A61M1/3486 , A61M2202/08 , C12M45/09 , C12N11/10 , C12N11/14
摘要： The present disclosure provides a biochemistry reactive material, including a substrate and an enzyme composition immobilized on the substrate. The enzyme composition is selected from a group consisting of a first enzyme, a second enzyme, and a combination thereof. The first enzyme is used for eliminating a glycan residue of an electronegative low-density lipoprotein (electronegative LDL). The second enzyme is used for eliminating ceramide carried by an electronegative low-density lipoprotein. The biochemistry reactive material is capable of eliminating electronegative low-density lipoprotein.
摘要翻译： 本公开提供了生物化学反应性材料，其包括固定在基材上的底物和酶组合物。 酶组合物选自第一酶，第二酶及其组合。 第一种酶用于消除电负性低密度脂蛋白（电负性LDL）的聚糖残基。 第二种酶用于消除由负电性低密度脂蛋白携带的神经酰胺。 生物化学反应性材料能够消除电负性低密度脂蛋白。
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公开(公告)号：US20210137699A1
公开(公告)日：2021-05-13
申请号：US16725481
申请日：2019-12-23
发明人： Fang-Jie JANG , Pei-I TSAI , Chih-Chieh HUANG , De-Yau LIN , Wei-Lun FAN , Yi-Hung WEN , Kuo-Yi YANG , Hsin-Hsin SHEN
摘要： The disclosure relates to a spinal intervertebral body fusion device including an adjustable spacer, a first and second pushing piece, and an operative piece. The adjustable spacer includes a first and second supporting plate. The first supporting plate portion is movably installed on the second supporting plate portion. The first and second supporting plate portions form a first and second opening respectively located at two opposite sides of the adjustable spacer. The first pushing piece located at the first opening and is partially clamped by the first and second supporting plate portions. The second pushing piece located at the second opening is partially clamped by the first and second supporting plate portions. The operative piece is movably disposed through the second pushing piece and screwed to the first pushing piece. The operative piece has an annular slot, and the second pushing piece is partially located in the annular slot.
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公开(公告)号：US20190010483A1
公开(公告)日：2019-01-10
申请号：US16137925
申请日：2018-09-21
发明人： Pei-Yi TSAI , Chih-Hung CHEN , Yi-Hung LIN , Chih-Chieh HUANG , Hsin-Hsin SHEN , Liang-Yin KE , Chu-Huang CHEN
摘要： A method for ex vivo treating blood or plasma is provided. The method includes (a) ex vivo contacting a blood or plasma with an enzyme composition to react the enzyme composition with the blood or plasma, wherein the enzyme composition is capable of eliminating electronegative low-density lipoprotein from the blood or plasma by the activity of the enzyme composition, and the enzyme composition is selected from a group consisting of: a first enzyme for eliminating a glycan residue of an electronegative low-density lipoprotein (LDL); a second enzyme for eliminating ceramide carried by a electronegative low-density lipoprotein (LDL); and a combination thereof; and (b) terminating contact between the blood or plasma and the enzyme composition to terminate the reaction of the enzyme composition with the blood or plasma.
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