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公开(公告)号：US20150150614A1
公开(公告)日：2015-06-04
申请号：US14554521
申请日：2014-11-26
发明人： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
CPC分类号： A61B17/8625 , A61B17/864 , A61B17/866 , A61L31/146 , A61L2430/02 , B33Y80/00
摘要： A bionic apparatus is provided. The bionic apparatus includes a flexible portion having a plurality of pores, a rigid portion connected with the flexible portion, and a supporting element disposed in the flexible portion. The pore size of each pore is between 50 μm to 500 μm. The flexible portion, the rigid portion and the supporting element are one-piece formed by a additive manufacturing process.
摘要翻译： 提供仿生设备。 仿生装置包括具有多个孔的柔性部分，与柔性部分连接的刚性部分和设置在柔性部分中的支撑元件。 各孔的孔径为50μm〜500μm。 柔性部分，刚性部分和支撑元件是通过添加剂制造工艺形成的一体的。
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公开(公告)号：US20150150557A1
公开(公告)日：2015-06-04
申请号：US14555251
申请日：2014-11-26
发明人： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
IPC分类号： A61B17/08
CPC分类号： A61B17/686 , A61F2/0811 , A61F2002/0835 , A61F2002/0864
摘要： A bionic fixing apparatus is provided. The bionic fixing apparatus includes a body having a through hole and at least one slit. The through hole penetrates the body from the top surface to the bottom surface to form a top opening and a bottom opening. An inner diameter of the top opening is larger than an inner diameter of the bottom opening. The slit is connected to the bottom opening and extends upwardly from the bottom surface of the body, such that the body has a flexible bottom portion.
摘要翻译： 提供仿生定影装置。 仿生定影装置包括具有通孔和至少一个狭缝的主体。 通孔从上表面穿透到底面，形成顶部开口和底部开口。 顶部开口的内径大于底部开口的内径。 狭缝连接到底部开口并从主体的底部表面向上延伸，使得主体具有柔性底部。
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公开(公告)号：US20150147722A1
公开(公告)日：2015-05-28
申请号：US14555204
申请日：2014-11-26
发明人： Pei-Yi TSAI , Chih-Chieh HUANG , Yi-Hung WEN , Hsin-Hsin SHEN , Yi-Hung LIN , De-Yau LIN , Jui-Sheng SUN , Chuan-Sheng CHUANG , An-Li CHEN , Ching-Chih LIN
CPC分类号： A61B17/8625 , A61B17/72 , A61C8/0018 , A61C8/0022 , A61C8/0037 , A61C2008/0046 , A61F2/442
摘要： A bionic fixing apparatus is provided. The bionic fixing apparatus includes a flexible portion having at least one trench. The trench is disposed on the surface of the flexible portion and has a first end and a second end. An interval is disposed between the first end and the second end. The trench is disposed for spreading the stress applied on the bionic fixing apparatus and preventing stress concentration and stress shielding.
摘要翻译： 提供仿生定影装置。 仿生定影装置包括具有至少一个沟槽的柔性部分。 沟槽设置在柔性部分的表面上并具有第一端和第二端。 间隔设置在第一端和第二端之间。 沟槽设置用于扩展施加在仿生定影装置上的应力，并且防止应力集中和应力屏蔽。
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公开(公告)号：US20190010483A1
公开(公告)日：2019-01-10
申请号：US16137925
申请日：2018-09-21
发明人： Pei-Yi TSAI , Chih-Hung CHEN , Yi-Hung LIN , Chih-Chieh HUANG , Hsin-Hsin SHEN , Liang-Yin KE , Chu-Huang CHEN
摘要： A method for ex vivo treating blood or plasma is provided. The method includes (a) ex vivo contacting a blood or plasma with an enzyme composition to react the enzyme composition with the blood or plasma, wherein the enzyme composition is capable of eliminating electronegative low-density lipoprotein from the blood or plasma by the activity of the enzyme composition, and the enzyme composition is selected from a group consisting of: a first enzyme for eliminating a glycan residue of an electronegative low-density lipoprotein (LDL); a second enzyme for eliminating ceramide carried by a electronegative low-density lipoprotein (LDL); and a combination thereof; and (b) terminating contact between the blood or plasma and the enzyme composition to terminate the reaction of the enzyme composition with the blood or plasma.
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5.发明申请BIOCHEMISTRY REACTIVE MATERIAL AND DEVICE FOR ELIMINATING ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN (LDL) AND METHOD FOR TREATING BLOOD OR PLASMA EX VIVO TO ELIMINATE ELECTRONEGATIVE LOW-DENSITY LIPOPROTEIN THEREIN 审中-公开用于消除电子低密度脂蛋白（LDL）的生物化学反应性材料和装置以及用于治疗血液或血浆的方法以消除电子密度低密度脂蛋白公开(公告)号：US20170044516A1
公开(公告)日：2017-02-16
申请号：US14984938
申请日：2015-12-30
发明人： Pei-Yi Tsai , Chih-Hung CHEN , Yi-Hung LIN , Chih-Chieh HUANG , Hsin-Hsin SHEN , Liang-Yin KE , Chu-Huang CHEN
CPC分类号： C12N11/12 , A61M1/3486 , A61M2202/08 , C12M45/09 , C12N11/10 , C12N11/14
摘要： The present disclosure provides a biochemistry reactive material, including a substrate and an enzyme composition immobilized on the substrate. The enzyme composition is selected from a group consisting of a first enzyme, a second enzyme, and a combination thereof. The first enzyme is used for eliminating a glycan residue of an electronegative low-density lipoprotein (electronegative LDL). The second enzyme is used for eliminating ceramide carried by an electronegative low-density lipoprotein. The biochemistry reactive material is capable of eliminating electronegative low-density lipoprotein.
摘要翻译： 本公开提供了生物化学反应性材料，其包括固定在基材上的底物和酶组合物。 酶组合物选自第一酶，第二酶及其组合。 第一种酶用于消除电负性低密度脂蛋白（电负性LDL）的聚糖残基。 第二种酶用于消除由负电性低密度脂蛋白携带的神经酰胺。 生物化学反应性材料能够消除电负性低密度脂蛋白。
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公开(公告)号：US20140220085A1
公开(公告)日：2014-08-07
申请号：US14251472
申请日：2014-04-11
发明人： Pei-Yi TSAI , Yi-Hung WEN , Zhi-Jie HUANG , Pei-Shan LI , Hsin-Hsin SHEN , Yi-Hung LIN , Chih-Hung CHEN
CPC分类号： A61L27/10 , A61L27/12 , A61L27/28 , A61L27/54 , A61L2300/624 , A61L2400/12 , C12N5/0068
摘要： In an embodiment of the disclosure, a biomedical material is provided. The biomedical material includes a biocompatible material having a surface and a carrier distributed over the surface of the biocompatible material, wherein both of the biocompatible material and the carrier have no charges, one of them has charges or both of them have charges with different electricity. The biomedical material is utilized for dentistry, orthopedics, wound healing or medical beauty and applied in the repair and regeneration of various soft and hard tissues.
摘要翻译： 在本公开的一个实施方案中，提供生物医学材料。 生物医学材料包括具有分布在生物相容性材料的表面上的表面和载体的生物相容性材料，其中生物相容性材料和载体都不具有电荷，其中之一具有电荷，或者两者都具有不同电荷的电荷。 生物医学材料用于牙科，骨科，伤口愈合或医疗美容，并用于各种软组织和硬组织的修复和再生。
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