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    Data storage based on encoded DNA sequences
    1.
    发明授权
    Data storage based on encoded DNA sequences 有权

    公开(公告)号：US11630863B2

    公开(公告)日：2023-04-18

    申请号：US17403791

    申请日：2021-08-16

    Applicant: Intel Corporation

    Inventor： Xing Su ,  Kai Wu ,  Noureddine Tayebi ,  Grace Credo

    IPC: G06F16/901 ,  H03M7/30 ,  G06F16/11 ,  G06F16/178 ,  G16B30/00 ,  G16B50/50

    Abstract: Devices, methods, and systems for encoding data as DNA are provided. An encoder device can include circuitry to encode a data file having a bit sequence encoding data and to generate a virtual DNA (VDNA) sequence of virtual nucleotide bases (Vnb) that reversibly encodes the bit sequence of the data file, divide the VDNA sequence into a plurality of VDNA fragments, associate each VDNA fragment with an archive library sequence (Arc_SEQ), and generate a read instruction (READ) sequence of differences between each VDNA fragment and each associated Arc_SEQ including sufficient instruction to facilitate regeneration of each VDNA fragment from each associated Arc_SEQ. A codeword sequence (Code_SEQ) is additionally generated for each VDNA fragment that includes a codename identifying the associated Arc_SEQ, the READ sequence associated with the VDNA fragment, and an index sequence (Idx_SEQ) including an index mapping of the VDNA fragment in the VDNA sequence.

    Data storage based on encoded DNA sequences
    3.
    发明授权
    Data storage based on encoded DNA sequences 有权

    公开(公告)号：US11093547B2

    公开(公告)日：2021-08-17

    申请号：US15929022

    申请日：2018-06-19

    Applicant: Intel Corporation

    Inventor： Xing Su ,  Kai Wu ,  Noureddine Tayebi ,  Grace Credo

    IPC: H03M7/00 ,  G06F16/901 ,  H03M7/30 ,  G06F16/11 ,  G06F16/178 ,  G16B30/00 ,  G16B50/50

    Abstract: Devices, methods, and systems for encoding data as DNA are provided. An encoder device can include an encoder engine configured to encode a data file having a bit sequence encoding data and further configured to generate a virtual DNA (VDNA) sequence of virtual nucleotide bases (Vnb) that reversibly encodes the bit sequence of the data file, divide the VDNA sequence into a plurality of VDNA fragments, associate each VDNA fragment with an archive library sequence (Arc_SEQ), and generate a read instruction (READ) sequence of differences between each VDNA fragment and each associated Arc_SEQ including sufficient instruction to facilitate regeneration of each VDNA fragment from each associated Arc_SEQ. A codeword sequence (Code_SEQ) is additionally generated for each VDNA fragment comprising a codename identifying the associated Arc_SEQ, the READ sequence associated with the VDNA fragment, and an index sequence (Idx_SEQ) including an index mapping of the VDNA fragment in the VDNA sequence.

    DEVICE AND METHOD FOR PARTICLE COMPLEX HANDLING
    4.
    发明申请
    DEVICE AND METHOD FOR PARTICLE COMPLEX HANDLING 审中-公开

    公开(公告)号：US20200166440A1

    公开(公告)日：2020-05-28

    申请号：US16778536

    申请日：2020-01-31

    Applicant: Intel Corporation

    Inventor： Xing Su ,  David J. Liu ,  Kai Wu ,  Kenneth B. Swartz ,  Mineo Yamakawa

    IPC: G01N1/40 ,  G01N35/08 ,  B01L3/00

    Abstract: An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.

    Integrated Photonics Based Sensor System
    5.
    发明申请
    Integrated Photonics Based Sensor System 审中-公开
    集成光子学传感器系统

    公开(公告)号：US20160282265A1

    公开(公告)日：2016-09-29

    申请号：US14669514

    申请日：2015-03-26

    Applicant: Intel Corporation

    Inventor： Xing Su ,  Kadhair Al-Hemyari ,  Kai Wu ,  Grace M. Credo ,  Haisheng Rong ,  Jacob Sendowski

    IPC: G01N21/41

    CPC classification number: G01N21/7746 ,  G01N21/39 ,  G01N21/553 ,  G01N2021/773 ,  G01N2021/7776

    Abstract: An embodiment includes a sensor comprising a substrate die; a photonic ring resonator (RR) on the substrate die; a polymer, on the RR, having an affinity to a chemical analyte; a photonic waveguide on the substrate die and coupled to the RR; a laser, on the substrate die and coupled to the waveguide, to emit optical energy that operates with the RR at a resonance wavelength; and a photodetector, on the substrate die and coupled to the waveguide, to detect a change in refractive index (RI) of the RR operating with the optical energy in response to the polymer coupling to the analyte. Other embodiments are described herein.

    Abstract translation: 一个实施例包括一个包括一个基片的传感器; 在衬底裸片上的光子环谐振器（RR）; RR上的聚合物对化学分析物具有亲和性; 衬底上的光子波导管并耦合到RR; 激光器，在基板裸片上并且耦合到波导，以发射与RR在谐振波长下工作的光能; 以及光电检测器，其在所述基板裸片上并耦合到所述波导，以检测响应于与所述分析物的所述聚合物耦合而用所述光能操作的所述RR的折射率（RI）的变化。 本文描述了其它实施例。

    DATA STORAGE BASED ON ENCODED DNA SEQUENCES
    6.
    发明申请
    DATA STORAGE BASED ON ENCODED DNA SEQUENCES 审中-公开

    公开(公告)号：US20190050495A1

    公开(公告)日：2019-02-14

    申请号：US15929022

    申请日：2018-06-19

    Applicant: Intel Corporation

    Inventor： Xing Su ,  Kai Wu ,  Noureddine Tayebi

    IPC: G06F17/30 ,  G06F19/22 ,  H03M7/30

    Abstract: Devices, methods, and systems for encoding data as DNA are provided. An encoder device can include an encoder engine configured to encode a data file having a bit sequence encoding data and further configured to generate a virtual DNA (VDNA) sequence of virtual nucleotide bases (Vnb) that reversibly encodes the bit sequence of the data file, divide the VDNA sequence into a plurality of VDNA fragments, associate each VDNA fragment with an archive library sequence (Arc_SEQ), and generate a read instruction (READ) sequence of differences between each VDNA fragment and each associated Arc_SEQ including sufficient instruction to facilitate regeneration of each VDNA fragment from each associated Arc_SEQ. A codeword sequence (Code_SEQ) is additionally generated for each VDNA fragment comprising a codename identifying the associated Arc_SEQ, the READ sequence associated with the VDNA fragment, and an index sequence (Idx_SEQ) including an index mapping of the VDNA fragment in the VDNA sequence.

    DEVICE AND METHOD FOR PARTICLE COMPLEX HANDLING
    9.
    发明申请
    DEVICE AND METHOD FOR PARTICLE COMPLEX HANDLING 审中-公开

    公开(公告)号：US20180372601A1

    公开(公告)日：2018-12-27

    申请号：US15865914

    申请日：2018-01-09

    Applicant: Intel Corporation

    Inventor： Xing Su ,  David J. Liu ,  Kai Wu ,  Kenneth B. Swartz ,  Mineo Yamakawa

    IPC: G01N1/40 ,  B01L3/00 ,  G01N35/08 ,  H01F7/20 ,  G01N15/00 ,  G01N35/00 ,  H01F7/06

    Abstract: An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.

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