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    Integrated circuit implementation and fault control system, device, and method
    1.
    发明授权
    Integrated circuit implementation and fault control system, device, and method 有权
    集成电路实现与故障控制系统，设备及方法

    公开(公告)号：US08473069B2

    公开(公告)日：2013-06-25

    申请号：US12920086

    申请日：2009-02-27

    申请人： Yafei Bi ,  Haifeng Li ,  Mark Zdeblick ,  Todd Thompson ,  Robert Leichner

    发明人： Yafei Bi ,  Haifeng Li ,  Mark Zdeblick ,  Todd Thompson ,  Robert Leichner

    IPC分类号： A61N1/08

    CPC分类号： A61N1/05 ,  A61N1/025 ,  A61N1/37 ,  A61N1/378

    摘要： Apparatus and methods enable robust, reliable control for implantable medical devices, including cardiac pacemakers, defibrillators and cardiac resynchronization devices. Integrated circuits in the devices have minimized interfaces, can derive power from the interface signals, and have high voltage and latch-up protection. A device lead has a power generation circuit and a switching circuit using cascaded PMOS transistors for operating with a stable voltage despite fluctuations in the supplied voltage. The lead has control electronics that provide a very low impedance between an electrode and a lead conductor during most of the duration of a pacing pulse, but during a brief initial portion of the pacing pulse, provide a very high impedance to permit charging up a power supply that is local to the control electronics. A method of stabilizing the external impedance and a system for fault detection and fault recovery for an implantable device are also provided.

    摘要翻译： 装置和方法能够对可植入医疗装置（包括心脏起搏器，除颤器和心脏再同步装置）进行可靠的，可靠的控制。 器件中的集成电路具有最小化的接口，可以从接口信号中获取功率，并具有高电压和闭锁保护。 器件引线具有发电电路和使用级联PMOS晶体管的开关电路，用于尽管工作电压的波动以稳定的电压工作。 引线具有控制电子学，其在起搏脉冲的大部分持续时间期间在电极和引线导体之间提供非常低的阻抗，但是在起搏脉冲的短暂初始部分期间，提供非常高的阻抗以允许充电电力 供应是本地控制电子产品。 还提供了一种稳定外部阻抗的方法和用于可植入装置的故障检测和故障恢复系统。

    Integrated Circuit Implementation and Fault Control System, Device, and Method
    2.
    发明申请
    Integrated Circuit Implementation and Fault Control System, Device, and Method 有权
    集成电路实现与故障控制系统，设备及方法

    公开(公告)号：US20110034964A1

    公开(公告)日：2011-02-10

    申请号：US12920086

    申请日：2009-02-27

    申请人： Yafei Bi ,  Haifeng Li ,  Mark Zdeblick ,  Todd Thompson ,  Robert Leichner

    发明人： Yafei Bi ,  Haifeng Li ,  Mark Zdeblick ,  Todd Thompson ,  Robert Leichner

    IPC分类号： A61N1/08 ,  A61N1/362 ,  A61N1/05 ,  A61N1/39

    CPC分类号： A61N1/05 ,  A61N1/025 ,  A61N1/37 ,  A61N1/378

    摘要： Apparatus and methods enable robust, reliable control for implantable medical devices, including cardiac pacemakers, defibrillators and cardiac resynchronization devices. Integrated circuits in the devices have minimized interfaces, can derive power from the interface signals, and have high voltage and latch-up protection. A device lead has a power generation circuit and a switching circuit using cascaded PMOS transistors for operating with a stable voltage despite fluctuations in the supplied voltage. The lead has control electronics that provide a very low impedance between an electrode and a lead conductor during most of the duration of a pacing pulse, but during a brief initial portion of the pacing pulse, provide a very high impedance to permit charging up a power supply that is local to the control electronics. A method of stabilizing the external impedance and a system for fault detection and fault recovery for an implantable device are also provided.

    摘要翻译： 装置和方法能够对可植入医疗装置（包括心脏起搏器，除颤器和心脏再同步装置）进行可靠的，可靠的控制。 器件中的集成电路具有最小化的接口，可以从接口信号中获取功率，并具有高电压和闭锁保护。 器件引线具有发电电路和使用级联PMOS晶体管的开关电路，用于尽管工作电压的波动以稳定的电压工作。 引线具有控制电子学，其在起搏脉冲的大部分持续时间期间在电极和引线导体之间提供非常低的阻抗，但是在起搏脉冲的短暂初始部分期间，提供非常高的阻抗以允许充电电力 供应是本地控制电子产品。 还提供了一种稳定外部阻抗的方法和用于可植入装置的故障检测和故障恢复系统。

    IMPLANTABLE INTEGRATED CIRCUIT
    3.
    发明申请
    IMPLANTABLE INTEGRATED CIRCUIT 审中-公开
    可嵌入式集成电路

    公开(公告)号：US20100204766A1

    公开(公告)日：2010-08-12

    申请号：US12097959

    申请日：2006-12-22

    申请人： Mark Zdeblick ,  Robert Leichner ,  Behrad Aria ,  Nilay Jani ,  Haifeng Li ,  Todd Thompson ,  Lawrence Arne ,  Timothy Robertson ,  Yafei Bi ,  Vladimier Gelfandbein

    发明人： Mark Zdeblick ,  Robert Leichner ,  Behrad Aria ,  Nilay Jani ,  Haifeng Li ,  Todd Thompson ,  Lawrence Arne ,  Timothy Robertson ,  Yafei Bi ,  Vladimier Gelfandbein

    IPC分类号： A61N1/05

    CPC分类号： A61N1/056 ,  A61B5/0422 ,  A61N1/025 ,  A61N1/362 ,  A61N1/3686 ,  A61N1/372 ,  A61N1/37205 ,  A61N1/37276 ,  A61N1/37288 ,  A61N1/3756

    摘要： Embodiments of the present invention enable robust, reliable control functionality for effectors present on intraluminal, e.g., vascular leads, as well as other types of implantable devices. Embodiments of the invention enable the required functionality for accurate long term control of effectors units, even ones present on multiplex carrier configurations, while provide for low power consumption. Aspects of the invention include implantable integrated circuits that have power extraction; energy storage; communication; and device configuration functional blocks, where these functional blocks are all present in a single integrated circuit on an intraluminal-sized support. Also provided by the invention are effector assemblies that include the integrated circuits, as well as implantable medical devices, e.g., pulse generators that include the same, as well as systems and kits thereof and methods of using the same, e.g., in pacing applications, including cardiac resynchronization therapy (CRT) applications.

    摘要翻译： 本发明的实施例对存在于管腔内（例如血管引线）以及其它类型的可植入装置的效果器提供了鲁棒，可靠的控制功能。 本发明的实施例能够实现对效果器单元的准确的长期控制所需的功能，即使存在于多路载波配置上的单元也能提供低功耗。 本发明的方面包括具有功率提取的可植入集成电路; 储能; 通讯; 以及器件配置功能块，其中这些功能块都存在于腔内尺寸支持体上的单个集成电路中。 本发明还提供了包括集成电路的效应器组件以及可植入的医疗装置，例如包括其的脉冲发生器，以及其系统和套件，以及使用该装置的方法，例如在起搏应用中， 包括心脏再同步治疗（CRT）应用。