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公开(公告)号：US20190013108A1
公开(公告)日：2019-01-10
申请号：US15998846
申请日：2018-08-17
发明人： Antero Abrunhosa , Vitor Alves , Francisco Alves
IPC分类号： G21G1/00 , B01J47/00 , B01J41/05 , G21G1/10 , C22B58/00 , C07B59/00 , B01J39/05 , B01J41/12 , B01J39/18 , A61K51/08
CPC分类号： G21G1/001 , A61K51/088 , B01J39/05 , B01J39/18 , B01J41/05 , B01J41/12 , B01J47/00 , C07B59/008 , C07B2200/05 , C22B58/00 , G21G1/10 , G21G2001/0021
摘要： The present disclosure relates to a process for purifying and concentrating 68Ga isotope produced by the irradiation with an accelerated particle beam of a 68Zn target in solution. The process according to the present disclosure allows for the production of pure and concentrated 68Ga isotope in hydrochloric acid solution. The present disclosure also relates to a disposable cassette for performing the steps of purification and concentration of the process.
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公开(公告)号：US10124191B2
公开(公告)日：2018-11-13
申请号：US14426913
申请日：2013-09-10
摘要： The invention relates to a hadron therapy installation that comprises an irradiation unit (1) supported by a rotary support structure, so as to be able to rotate around a target volume (15) centered on the axis of rotation (22), to deliver a treatment beam (17) from different angles on the target volume (15). An imaging device (3, 4) is secured in rotation with the irradiation unit (1) and translatable relative to the irradiation unit (1) between a retracted position at the irradiation unit (1) and a lateral deployed position relative to the target volume (15), such that in its deployed position, the imaging device (3, 4) can rotate around the target volume (15) together with the irradiation unit (1). Such an installation can be used for a cone beam computed tomography method and/or a fluoroscopic imaging method on a patient to be treated in the hadron therapy installation.
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93.发明授权公开(公告)号：US09968321B2
公开(公告)日：2018-05-15
申请号：US14975683
申请日：2015-12-18
发明人： David Wikler
CPC分类号： A61B6/486 , A61B6/032 , A61B6/4085 , A61B6/488 , A61B6/5288 , A61N5/1037
摘要： Disclosed systems and methods may include an imaging system. The imaging system may include a 4D-CBCT apparatus able to generate a plurality of CBCT images corresponding to different temporal phases. The imaging system may also include a radiographic apparatus able to generate a radiograph. Further, the imaging system may include a synchronization device for correlating a radiograph of said radiographic apparatus with a CBCT image generated by said 4D-CBCT apparatus, such that a reference radiograph can be determined.
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公开(公告)号：US20180130568A1
公开(公告)日：2018-05-10
申请号：US15805647
申请日：2017-11-07
CPC分类号： G21K5/04 , G21K1/093 , H05H7/18 , H05H13/10 , H05H2245/1225 , H05H2277/14
摘要： An electron accelerator comprising a resonant cavity, an electron source, an RF system, and at least one magnet unit is provided. The resonant cavity further comprises a hollow closed conductor and the electron source is configured to radially inject a beam of electrons into the cavity. The RF system is configured to generate an electric field to accelerate the electrons along radial trajectories. The at least one magnet unit further comprises a deflecting magnet configured to generate a magnetic field that deflects an electron beam emerging out of the resonant cavity along a first radial trajectory and redirects the electron beam into the resonant cavity along a second radial trajectory. The resonant cavity further comprises a first half shell, a second half shell, and a central ring element.
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公开(公告)号：US20180099158A1
公开(公告)日：2018-04-12
申请号：US15727544
申请日：2017-10-06
发明人： Caterina BRUSASCO
IPC分类号： A61N5/10 , G01R33/421
CPC分类号： A61N5/1049 , A61N5/1043 , A61N5/1081 , A61N2005/1055 , A61N2005/1087 , G01R33/3873 , G01R33/4215
摘要： The present disclosure relates to a particle therapy apparatus for irradiating a target with a charged particle beam. In one implementation, the apparatus includes an isocentric gantry rotatable about an axis and configured to direct a particle beam towards an isocenter of gantry and according to a final beam direction, a magnetic resonance imaging system configured to generate a main magnetic field parallel to the final beam direction, and a passive magnetic shield surrounding the magnetic resonance imaging system, the passive magnetic shield and the magnetic resonance imaging system being synchronously rotatable with the gantry about the axis.
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96.发明申请公开(公告)号：US20180099157A1
公开(公告)日：2018-04-12
申请号：US15727379
申请日：2017-10-06
CPC分类号： A61N5/1048 , A61B5/055 , A61B5/742 , A61B5/7425 , A61B5/743 , A61N5/103 , A61N5/1049 , A61N5/1067 , A61N5/1077 , A61N2005/1055 , A61N2005/1087 , G01R33/4808 , G01R33/4838 , G01R33/5602
摘要： The present disclosure relates to a method and a medical apparatus for visualizing a hadron beam traversing an organic body. In one implementation, the method may include capturing a magnetic resonance (MR) image including a volume of irradiated excitable atoms surrounding a hadron beam and having a magnetic susceptibility modified by the hadron beam captured as a hyposignal. For example, a hyposignal may be obtained by saturating the spins of the irradiated excitable atoms before capturing an MR image based on excitation of excitable atoms not affected by the hadron beam.
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公开(公告)号：US09941027B2
公开(公告)日：2018-04-10
申请号：US14350524
申请日：2012-10-10
发明人： Eric Kral , Xavier Wilputte , Michel Ghyoot , Jean-Michel Geets
IPC分类号： G21G1/10
CPC分类号： G21G1/10
摘要： The invention relates to a method for producing a radioisotope, which method comprises irradiating a volume of radioisotope-precursor fluid contained in a sealed cell of a target using a beam of particles of a given current, which beam is produced by a particle accelerator. The target is cooled and the internal pressure in the sealed cell is measured. During the irradiation, the internal pressure (P) in the sealed cell is allowed to vary freely. The irradiation is interrupted or its intensity is reduced when the internal pressure (P) in the sealed cell departs from a first tolerated range defined depending on various parameters that influence the variation in the internal pressure in the sealed cell during the irradiation. These parameters for example comprise, for a given target, particle beam and radioisotope-precursor fluid: the degree of filling of the hermetic cell, the cooling power used to cool the given target, and the beam current (I). The invention also relates to an installation for implementing the method.
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公开(公告)号：US09901752B2
公开(公告)日：2018-02-27
申请号：US14426892
申请日：2013-09-10
发明人： Vincent Piret
IPC分类号： A61N5/10
CPC分类号： A61N5/1081 , A61N5/1048 , A61N2005/105 , A61N2005/1061 , A61N2005/1085 , A61N2005/1087
摘要： The present disclosure relates to a hadron therapy installation comprising a moving floor in the form of a deformable band guided in a guide structure. The moving floor comprises a lower segment and an upper segment. The lower segment can be pulled by the irradiation unit from a lower docked position to a position in which the lower segment forms a substantially horizontal floor surface when the irradiation unit is in a first angular position. The upper segment can be pulled by the irradiation unit from an upper docked position to a position in which the upper segment at least partially forms the substantially horizontal floor surface when the irradiation unit is in a second angular position. The lower segment and the upper segment may have a finite length and a counterweight further connected to the free end of the upper segment.
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公开(公告)号：US20170332475A1
公开(公告)日：2017-11-16
申请号：US15594527
申请日：2017-05-12
发明人： Willem Kleeven , Michel Abs
CPC分类号： H05H7/10 , H01F3/10 , H01F7/02 , H01F7/20 , H05H7/001 , H05H7/04 , H05H13/005 , H05H13/08 , H05H2007/002 , H05H2007/043
摘要： The present disclosure relates to a magnet pole for an isochronous sector-focused cyclotron having hill and valley sectors alternatively distributed around a central axis, Z, each hill sector having an upper surface bounded by four edges: an upper peripheral edge, an upper central edge, a first and a second upper lateral edges. The upper peripheral edge of a hill sector may be an arc of circle whose center is offset with respect to the central axis, and whose radius, Rh, is not more than 85% of a distance, Lh, from the central axis to a midpoint of the upper peripheral edge. Furthermore, the midpoint may be equidistant to the first and second upper distal ends.
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公开(公告)号：US09789343B2
公开(公告)日：2017-10-17
申请号：US14779790
申请日：2014-03-26
IPC分类号： A61N5/10
CPC分类号： A61N5/1083 , A61N5/1042 , A61N5/1043 , A61N5/1077 , A61N2005/1074 , A61N2005/1087 , A61N2005/1095
摘要： The present disclosure relates to an accessory holder attachable to or integrated in the nozzle of an apparatus for particle beam irradiation treatment. The accessory may be an aperture piece, a range shifter or any other element that can be placed in the beam path between the outer end of the nozzle and the irradiated target. The accessory holder may be equipped with first displacement means for moving the accessory away from or towards the nozzle, thereby moving the accessory forwards and backwards in the direction of the beam and second displacement means for moving the accessory into or out of the beam path. Measurements or treatment steps may be performed with and without the accessory in the beam path, without interrupting the treatment.
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